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Search Results: 1 - 10 of 958 matches for " Strive Tanja "
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A sensitive and specific blocking ELISA for the detection of rabbit calicivirus RCV-A1 antibodies
Liu June,Kerr Peter J,Strive Tanja
Virology Journal , 2012, DOI: 10.1186/1743-422x-9-182
Abstract: Background Antibodies to non-pathogenic rabbit caliciviruses (RCVs) cross-react in serological tests for rabbit hemorrhagic disease virus (RHDV) and vice versa, making epidemiological studies very difficult where both viruses occur. It is important to understand the distribution and interaction of the two viruses because the highly pathogenic RHDV has been used as a biocontrol agent for wild rabbits in Australia and New Zealand for the past 17 years. The presence of the benign RCV Australia 1 (RCV-A1) is considered a key factor for the failure of RHDV mediated rabbit control in cooler, wetter areas of Australia. Results A highly sensitive and specific blocking ELISA was developed for the detection of RCV-A1 antibodies. When sera from rabbits with a known infection history for either RCV-A1 or RHDV were tested, this assay showed 100% sensitivity and no cross-reactivity with RHDV sera (100% specificity). Conclusions This new ELISA not only allows the detection of RCV-A1 at a population level, but also permits the serological status of individual rabbits to be determined more reliably than previously described methods. This robust and simple to perform assay is therefore the tool of choice for studying RCV-A1 epidemiology in Australian wild rabbit populations.
Histo-Blood Group Antigens Act as Attachment Factors of Rabbit Hemorrhagic Disease Virus Infection in a Virus Strain-Dependent Manner
Kristina Nystr?m,Ghislaine Le Gall-Reculé,Paola Grassi,Joana Abrantes,Nathalie Ruvo?n-Clouet,Beatrice Le Moullac-Vaidye,Ana M. Lopes,Pedro J. Esteves,Tanja Strive,Stéphane Marchandeau,Anne Dell,Stuart M. Haslam,Jacques Le Pendu
PLOS Pathogens , 2011, DOI: 10.1371/journal.ppat.1002188
Abstract: Rabbit Hemorrhagic disease virus (RHDV), a calicivirus of the Lagovirus genus, and responsible for rabbit hemorrhagic disease (RHD), kills rabbits between 48 to 72 hours post infection with mortality rates as high as 50–90%. Caliciviruses, including noroviruses and RHDV, have been shown to bind histo-blood group antigens (HBGA) and human non-secretor individuals lacking ABH antigens in epithelia have been found to be resistant to norovirus infection. RHDV virus-like particles have previously been shown to bind the H type 2 and A antigens. In this study we present a comprehensive assessment of the strain-specific binding patterns of different RHDV isolates to HBGAs. We characterized the HBGA expression in the duodenum of wild and domestic rabbits by mass spectrometry and relative quantification of A, B and H type 2 expression. A detailed binding analysis of a range of RHDV strains, to synthetic sugars and human red blood cells, as well as to rabbit duodenum, a likely gastrointestinal site for viral entrance was performed. Enzymatic cleavage of HBGA epitopes confirmed binding specificity. Binding was observed to blood group B, A and H type 2 epitopes in a strain-dependent manner with slight differences in specificity for A, B or H epitopes allowing RHDV strains to preferentially recognize different subgroups of animals. Strains related to the earliest described RHDV outbreak were not able to bind A, whereas all other genotypes have acquired A binding. In an experimental infection study, rabbits lacking the correct HBGA ligands were resistant to lethal RHDV infection at low challenge doses. Similarly, survivors of outbreaks in wild populations showed increased frequency of weak binding phenotypes, indicating selection for host resistance depending on the strain circulating in the population. HBGAs thus act as attachment factors facilitating infection, while their polymorphism of expression could contribute to generate genetic resistance to RHDV at the population level.
Teaching PCA through Letter Recognition  [PDF]
Tanja Van Hecke
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.23040
Abstract: This article presents the use of a real life problem to reach a deeper understanding among students of the benefits of principal components analysis. Pattern recognition applied on the 26 letters of the alphabet is a recognizable topic for the students. Moreover it is still verifiable with computer algebra software. By means of well defined exercises the student can be guided in an active way through the learning process.
Influence of Random Pinning on the Crystallization Process in Suspensions of Hard Spheres  [PDF]
Sven Dorosz, Tanja Schilling
Journal of Crystallization Process and Technology (JCPT) , 2014, DOI: 10.4236/jcpt.2014.42012
Abstract: We discuss crystal formation in supersaturated suspensions of monodisperse hard spheres with a concentration of hard spheres randomly pinned in space and time. The pinning procedure introduces an external length scale and an external time scale that restrict the accessible number of configureurations and ultimately the number of pathways leading to crystallization. We observe a significant drop in the nucleation rate density at a characteristic pinning concentration that can be directly related to the structure of the critical nucleus and the dynamics of its formation in the unpinned system.
Appendix 3: Summary of the Evaluation of the Seminar The Effective Library”
Tanja Notten
Liber Quarterly : The Journal of European Research Libraries , 2002,
Abstract:
Steuergruppen von Schulnetzwerken: Gestaltungsm glichkeiten durch Distinktionen in Erweiterungsprozessen Steering Committee Members in School Networks: Distinctions in Admission Processes Miembros del Comité Directivo en las redes escolares: Distinciones en los procesos de admisión
Tanja Sturm
Forum : Qualitative Social Research , 2010,
Abstract: Netzwerke, in denen Personen kooperieren, um im Schulsystem nachhaltige Schul- und Professionalit tsentwicklung zu initiieren und zu etablieren, werden seit Ende der 1990er Jahre zunehmend aufgebaut. Netzwerke sind meist interessiert, sich auszuweiten, um m glichst viele Lehrende in Innovationen einzubeziehen. Steuergruppen stellen das operative Zentrum von Netzwerken dar. Sie übernehmen die Koordination und Organisation der Schulentwicklungsinitiativen eines Netzwerks und dienen als solche u.a. als Schnittstelle zwischen den bereits kooperierenden und potenziell neuen Mitgliedern. Bislang gibt es jedoch kaum Erkenntnisse darüber, wie die Steuergruppenmitglieder diesen Vermittlungsprozess gestalten und woran sie sich dabei orientieren. In diesem Beitrag soll an diesem Forschungsdesiderat angesetzt werden, indem die von Steuergruppenmitgliedern formulierten Zugangsm glichkeiten zum Netzwerk untersucht werden, die im Rahmen einer qualitativ angelegten Studie mithilfe problemzentrierter Interviews erhoben wurden. Die Befragungen wurden im Winter 2007/8 im Rahmen der sterreichischen Regionalen Netzwerke, einer von vier Ma nahmen eines landesweiten Projekts zur St rkung des mathematisch-naturwissenschaftlichen Unterrichts, durchgeführt. Drei unterschiedlich ausgestaltete Vermittlungsprozesse, die sich im Spannungsfeld von Sach- und Schulstrukturorientierung einerseits und den Vorstellungen zu inhaltlichen Gemeinsamkeiten und Unterschieden innerhalb des Netzwerks andererseits bewegen, konnten aus den Interviews generiert werden. Die drei rekonstruierten Typen von Zugangsm glichkeiten – sachlich-homogen, sachlich-heterogen und bürokratisch-homogen – die durch sogenannte Distinktionen, d.h. habituell vorgenommene Bewertungsformen, realisiert werden, werden anhand von Fallbeispielen illustriert und miteinander kontrastiert. Auf der Grundlage der Ergebnisse werden (Forschungs-) Perspektiven für den Einsatz des Entwicklungsansatzes der Schulnetzwerke formuliert. URN: urn:nbn:de:0114-fqs1003234 School networks—defined as people cooperating in order to initiate and emphasize school and professional development—have been established in German speaking areas since the beginning of the 1990s. One of their common goals is to raise the number of their active members. This purpose is connected to the idea of incorporating as many teachers as possible into possible innovations of the network. Steering committees are the operation centers of these kinds of school networks. They coordinate and organize the school and professional development initiatives of a network. Therefo
Music libraries and collections in Slovenia and abroad: characteristics and development trends
Tanja Curhalek
Knji?nica : Revija za Podro?je Bibliotekarstva in Informacijske Znanosti , 2003,
Abstract: Music libraries and collections with their materials, equipment and activities differ from general libraries, which mostly contain book materials. Library users are searching daily for more non-book music materials, specific for music libraries and collections, therefore detailed research on the situation and organization of such libraries and collections should be made. A detailed research was carried out on comprehensive Slovenian music libraries and collections. Consequently, a view was obtained of the situation of music librarianship in Slovenia, using a questionnaire and by communicating with librarians of the Music Collection of the National and University Library in Ljubljana, the Library of Department of Musicology at the Faculty of Arts in Ljubljana and the Library of the Academy of Music in Ljubljana, during the years 2000 and 2002. The research showed that music librarianship is not developed enough and that the Slovene public knows little about it, while in foreign countries libraries are contemporarily developed, well organized and extended, forming professional associations.
Ethno linguistic material regarding Christmas rituals among the Serbs in Bela Krajina
Petrovi? Tanja
Ju?noslovenski Filolog , 2002, DOI: 10.2298/jfi0258065p
Abstract: The paper aims at presenting the current ethno linguistic situation in four Orthodox Serbian villages in the Bela Krajina region of Slovenia. Ethno linguistic material collected in these villages enables the synchronic state of traditional culture to be established. Special attention is payed to the way the interviewees describe Christmas rituals and interpret and evaluate then-present state; apart from description of Christmas interviewees' statements (here named ethno linguistic texts) also carry precious information about attitudes of carriers of a certain culture towards its values, and indicate in- and out-group relations, establishing oppositions such as then vs. now, me vs. them, us vs. them. These subjective comments provided by the interviewees help obtain a complete, multilevel picture of a traditional culture, with all interactions that characterize it, both within the ethno linguistic community and in relation to other communities. It is especially important that these interactions be taken into account for isolated ethnic and linguistic groups such as the Orthodox Serbs in Bela Krajina.
Sonderf lle der Regelungen des Blutgeldes und des Ehrenpreises bei den Kelten
Tanja Wegner
Forum Historiae Iuris , 1998,
Abstract:
Ideological functions of reported speech in the process of language shift: The case of the Serbs of Bela Krajina
Petrovi? Tanja
Ju?noslovenski Filolog , 2005, DOI: 10.2298/jfi0561191p
Abstract: The article deals with ideological functions of direct and indirect speech the discursive forms which, due to their reflexive potential, enable speakers to express their views on social reality through language use. The use of reported speech combined with code switching enables speakers to establish various relations and attitudes towards other members of their community as well as towards other communities' members. For the members of the oldest generation of the Serbs of Bela Krajina, reported speech is also employed to express authority, which is one of the principal ideological dimensions that may be read out from their discourse.
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