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Search Results: 1 - 10 of 55258 matches for " Stephen Kin Yong Chang "
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Intestinal Obstruction in Pregnancy: A Case Report
Shakina Rauff,Stephen Kin Yong Chang,Eng Kien Tan
Case Reports in Obstetrics and Gynecology , 2013, DOI: 10.1155/2013/564838
Abstract:
Single Port Laparoscopic Liver Resection for Hepatocellular Carcinoma: A Preliminary Report
Stephen Kin Yong Chang,Maria Mayasari,Iyer Shridhar Ganpathi,Victor Lee Tswen Wen,Krishnakumar Madhavan
International Journal of Hepatology , 2011, DOI: 10.4061/2011/579203
Abstract: Single port laparoscopic surgery is an emerging technique, now commonly used in cholecystectomy. The experience of using this technique in liver resection for hepatocellular carcinoma is described in a series of 3 cases with single port laparoscopic liver resection performed during 2010. All patients were male aged 61 to 70 years, with several comorbidities. There were no complications in this early series. The length of hospital stay was 3–5 days. The blood loss was 200–450 mL, with operating time between 142 and 171 minutes. We conclude that this technique is feasible and safe to perform in experienced centers.
Single Port Laparoscopic Liver Resection for Hepatocellular Carcinoma: A Preliminary Report
Stephen Kin Yong Chang,Maria Mayasari,Iyer Shridhar Ganpathi,Victor Lee Tswen Wen,Krishnakumar Madhavan
International Journal of Hepatology , 2011, DOI: 10.4061/2011/579203
Abstract: Single port laparoscopic surgery is an emerging technique, now commonly used in cholecystectomy. The experience of using this technique in liver resection for hepatocellular carcinoma is described in a series of 3 cases with single port laparoscopic liver resection performed during 2010. All patients were male aged 61 to 70 years, with several comorbidities. There were no complications in this early series. The length of hospital stay was 3–5 days. The blood loss was 200–450?mL, with operating time between 142 and 171 minutes. We conclude that this technique is feasible and safe to perform in experienced centers. 1. Introduction Laparoscopic liver resection has been increasingly performed over the last two decades. The technique has improved since the first time it was published [1] in 1992. Each year, there has been considerable number of cases undergoing this technique. Consecutive reports have shown that liver resection can be done efficiently and safely using laparoscopic approach. Several potential advantages include less abdominal pain, less hospital stay, and some reports [2, 3] even suggest less operating time with less morbidity. Single port laparoscopic surgery was reported as early as 1992 [4]. First described as an effort to reduce abdominal trauma in appendix removal, this approach has extended its indications to a variety of cases. One potential problem arising from this approach is the loss of triangular movement traditionally achieved with conventional laparoscopic surgery. In 2010, there were several publications [5–9] regarding single port laparoscopic liver resections. However these reports have limited coverage of this technique as a treatment for hepatocellular carcinoma (HCC). This study aims to report the feasibility and safety of single port laparoscopic liver resection technique for treatment of hepatocellular cancer in a single institution. 2. Methods During 2010, all single port laparoscopic liver resection cases with proven histology findings of HCC were included in this paper. Demographic data, length of operation, operation technique, resection margin, blood loss, early post-op complications, and length of stay were evaluated for these patients. Postoperative followup was done until the end of 2010. 3. Surgical Technique Patients were put under general anaesthesia in the French position. Incision was made according to the need to place the port. For GelPort (Applied Medical, Calif, USA), a 5?cm upper umbilical midline incision was made. For the SILS port (Covidien, Dublin, Ireland), a midline incision through the umbilicus
SILC for SILC: Single Institution Learning Curve for Single-Incision Laparoscopic Cholecystectomy
Chee Wei Tay,Liang Shen,Mikael Hartman,Shridhar Ganpathi Iyer,Krishnakumar Madhavan,Stephen Kin Yong Chang
Minimally Invasive Surgery , 2013, DOI: 10.1155/2013/381628
Abstract: Objectives. We report the single-incision laparoscopic cholecystectomy (SILC) learning experience of 2 hepatobiliary surgeons and the factors that could influence the learning curve of SILC. Methods. Patients who underwent SILC by Surgeons A and B were studied retrospectively. Operating time, conversion rate, reason for conversion, identity of first assistants, and their experience with previous laparoscopic cholecystectomy (LC) were analysed. CUSUM analysis is used to identify learning curve. Results. Hundred and nineteen SILC cases were performed by Surgeons A and B, respectively. Eight cases required additional port. In CUSUM analysis, most conversion occurred during the first 19 cases. Operating time was significantly lower (62.5 versus 90.6?min, P = 0.04) after the learning curve has been overcome. Operating time decreases as the experience increases, especially Surgeon B. Most conversions are due to adhesion at Calot’s triangle. Acute cholecystitis, patients’ BMI, and previous surgery do not seem to influence conversion rate. Mean operating times of cases assisted by first assistant with and without LC experience were 48 and 74 minutes, respectively (P = 0.004). Conclusion. Nineteen cases are needed to overcome the learning curve of SILC. Team work, assistant with CLC experience, and appropriate equipment and technique are the important factors in performing SILC. 1. Introduction Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed for benign gallbladder disease over the last few years with comparable operative results with conventional 4-port laparoscopic cholecystectomy (CLC). With results from randomized controlled trials (RCTs) [1–5] and series of publications [6–9] showing that SILC is equally safe, with no obvious additional scar and potentially have less postoperative pain and earlier return to daily activity [5], more surgeons are embarking on learning the technique. As SILC is a new approach to gallbladder disease, many aspects of this new technique have not been studied in detail. Most surgeons embarking on this technique are concerned with its learning curve, conversions, and potential longer operating time. To date, very limited work has been done to look into this important issue and few publications have looked into learning curve of SILC from conversion point of view. To perform SILC safely and successfully, there may be changes in surgical technique, need of new equipment, and modifications in the role of assistant. In this study, we report an SILC learning experience of a tertiary university hospital
Comparative distribution of human and avian type sialic acid influenza receptors in the pig
Rahul K Nelli, Suresh V Kuchipudi, Gavin A White, Belinda Perez, Stephen P Dunham, Kin-Chow Chang
BMC Veterinary Research , 2010, DOI: 10.1186/1746-6148-6-4
Abstract: Both SAα2,3-Gal and SAα2,6-Gal receptors were extensively detected in the major porcine organs examined (trachea, lung, liver, kidney, spleen, heart, skeletal muscle, cerebrum, small intestine and colon). Furthermore, distribution of both SA receptors in the pig respiratory tract closely resembled the published data of the human tract. Similar expression patterns of SA receptors between pig and human in other major organs were found, with exception of the intestinal tract. Unlike the limited reports on the scarcity of influenza receptors in human intestines, we found increasing presence of SAα2,3-Gal and SAα2,6-Gal receptors from duodenum to colon in the pig.The extensive presence of SAα2,3-Gal and SAα2,6-Gal receptors in the major organs examined suggests that each major organ may be permissive to influenza virus entry or infection. The high similarity of SA expression patterns between pig and human, in particular in the respiratory tract, suggests that pigs are not more likely to be potential hosts for virus reassortment than humans. Our finding of relative abundance of SA receptors in the pig intestines highlights a need for clarification on the presence of SA receptors in the human intestinal tract.Influenza A viruses have a wide host range for birds and mammals, posing a major threat to animal health as well as a zoonotic threat to humans [1]. Influenza pandemics can arise from genetic reassortment between avian and human influenza viruses or alternatively by the direct adaptation of avian or mammalian viruses to efficient human to human transmission [2]. Swine influenza is a major respiratory problem in pigs; in uncomplicated infections the condition is usually mild to moderate and non-fatal, with complete recovery within 2 weeks after the onset of clinical signs. The 2009 pandemic H1N1 virus in experimentally infected pigs has been shown to produce similarly mild to moderate signs and pathology [3] as in most human cases of the same virus. The pig is often de
Standard Colonic Lavage Alters the Natural State of Mucosal-Associated Microbiota in the Human Colon
Laura Harrell, Yunwei Wang, Dionysios Antonopoulos, Vincent Young, Lev Lichtenstein, Yong Huang, Stephen Hanauer, Eugene Chang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032545
Abstract: Background & Aims Past studies of the human intestinal microbiota are potentially confounded by the common practice of using bowel-cleansing preparations. We examined if colonic lavage changes the natural state of enteric mucosal-adherent microbes in healthy human subjects. Methods Twelve healthy individuals were divided into three groups; experimental group, control group one, and control group two. Subjects in the experimental group underwent an un-prepped flexible sigmoidoscopy with biopsies. Within two weeks, subjects were given a standard polyethylene glycol-based bowel cleansing preparation followed by a second flexible sigmoidoscopy. Subjects in control group one underwent two un-prepped flexible sigmoidoscopies within one week. Subjects in the second control group underwent an un-prepped flexible sigmoidoscopy followed by a second flexible sigmoidoscopy after a 24-hour clear liquid diet within one week. The mucosa-associated microbial communities from the two procedures in each subject were compared using 16S rRNA gene based terminal restriction fragment length polymorphism (T-RFLP), and library cloning and sequencing. Results Clone library sequencing analysis showed that there were changes in the composition of the mucosa-associated microbiota in subjects after colonic lavage. These changes were not observed in our control groups. Standard bowel preparation altered the diversity of mucosa-associated microbiota. Taxonomic classification did not reveal significant changes at the phylum level, but there were differences observed at the genus level. Conclusion Standard bowel cleansing preparation altered the mucosal-adherent microbiota in all of our subjects, although the degree of change was variable. These findings underscore the importance of considering the confounding effects of bowel preparation when designing experiments exploring the gut microbiota.
The Call-by-need Lambda Calculus, Revisited
Stephen Chang,Matthias Felleisen
Computer Science , 2012,
Abstract: The existing call-by-need lambda calculi describe lazy evaluation via equational logics. A programmer can use these logics to safely ascertain whether one term is behaviorally equivalent to another or to determine the value of a lazy program. However, neither of the existing calculi models evaluation in a way that matches lazy implementations. Both calculi suffer from the same two problems. First, the calculi never discard function calls, even after they are completely resolved. Second, the calculi include re-association axioms even though these axioms are merely administrative steps with no counterpart in any implementation. In this paper, we present an alternative axiomatization of lazy evaluation using a single axiom. It eliminates both the function call retention problem and the extraneous re-association axioms. Our axiom uses a grammar of contexts to describe the exact notion of a needed computation. Like its predecessors, our new calculus satisfies consistency and standardization properties and is thus suitable for reasoning about behavioral equivalence. In addition, we establish a correspondence between our semantics and Launchbury's natural semantics.
A Model for Teaching, Assessment and Learning in Engineering Education for Working Adults
Kin Chew Lim,Stephen Low,Samir Attallah,Philip Cheang
International Journal of Advanced Corporate Learning (iJAC) , 2012, DOI: 10.3991/ijac.v5i4.2249
Abstract: This paper examines the engineering education programs provided by SIM University (UniSIM) especially in the teaching, assessment, and learning for working adults. In terms of engineering education, the paper emphasized the changes brought about especially in areas like blended learning, capstone project, continuous assessment, quality control and working with engineering accreditation bodies like ABET. All these helped to ensure that UniSIM is able to offer a quality engineering education that is comparable to other institutions in the region and can serve as a model for working adults to upgrade themselves.
Electric-field control of spin-orbit torque in a magnetically doped topological insulator
Yabin Fan,Xufeng Kou,Pramey Upadhyaya,Qiming Shao,Lei Pan,Murong Lang,Xiaoyu Che,Jianshi Tang,Mohammad Montazeri,Koichi Murata,Li-Te Chang,Mustafa Akyol,Guoqiang Yu,Tianxiao Nie,Kin L. Wong,Jun Liu,Yong Wang,Yaroslav Tserkovnyak,Kang L. Wang
Physics , 2015,
Abstract: Electric-field manipulation of magnetic order has proved of both fundamental and technological importance in spintronic devices. So far, electric-field control of ferromagnetism, magnetization and magnetic anisotropy has been explored in various magnetic materials, but the efficient electric-field control of spin-orbit torque (SOT) still remains elusive. Here, we report the effective electric-field control of a giant SOT in a Cr-doped topological insulator (TI) thin film using a top-gate FET structure. The SOT strength can be modulated by a factor of 4 within the accessible gate voltage range, and it shows strong correlation with the spin-polarized surface current in the film. Furthermore, we demonstrate the magnetization switching by scanning gate voltage with constant current and in-plane magnetic field applied in the film. The effective electric-field control of SOT and the giant spin-torque efficiency in Cr-doped TI may lead to the development of energy-efficient gate-controlled spin-torque devices compatible with modern field-effect semiconductor technologies.
Quantum algorithms for a set of group theoretic problems
Stephen Fenner,Yong Zhang
Physics , 2004,
Abstract: We study two group theoretic problems, GROUP INTERSECTION and DOUBLE COSET MEMBERSHIP, in the setting of black-box groups, where DOUBLE COSET MEMBERSHIP generalizes a set of problems, including GROUP MEMBERSHIP, GROUP FACTORIZATION, and COSET INTERSECTION. No polynomial-time classical algorithms are known for these problems. We show that for solvable groups, there exist efficient quantum algorithms for GROUP INTERSECTION if one of the underlying solvable groups has a smoothly solvable commutator subgroup, and for DOUBLE COSET MEMBERSHIP if one of the underlying solvable groups is smoothly solvable. We also study the decision versions of STABILIZER and ORBIT COSET, which generalizes GROUP INTERSECTION and DOUBLE COSET MEMBERSHIP, respectively. We show that they reduce to ORBIT COSET under certain conditions. Finally, we show that DOUBLE COSET MEMBERSHIP and DOUBLE COSET NONMEMBERSHIP have zero knowledge proof systems.
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