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Search Results: 1 - 10 of 170083 matches for " Stephanie E. Burgess "
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Psychometric Assessment of the Burgess-Partner Abuse Scale for Teens (B-PAST)
Burgess,Stephanie E; Tavakoli,Abbas;
Aquichán , 2005,
Abstract: purpose. the purpose of this study was to assess the psychometric properties of the burgess-partner abuse scale for teens (b-past) by examining internal consistency and construct validity. methods. a convenience sample of 239 teen girls ages 13 to 19 years old that were seen in three private primary health care practices agreed to participate. subjects were administered two measures of interpersonal violence, two measures of psychosocial well-being, and a demographic questionnaire. construct validity was assessed by 1) conducting exploratory factor analysis with a priori decision to retain two factors, and 2) measuring differential correlates of interpersonal violence and psychosocial well-being using pearson correlation. in order to determine the instrument's ability to discriminate between teen girls who reported partner abuse and those who did not report partner abuse, differences in contrasted group means (abused vs. non-abused) were examined. one-way anova was used to determine differences in interpersonal violence and psychosocial wellbeing. the internal consistency of the b-past was examined by setting a criterion for the alpha coefficient above .70. results. the results showed that 70.9% of the variance was explained by the b-past. factor analysis demonstrated a 22-item scale with two distinct subscales. the b-past correlated with one measure of interpersonal peer violence (r = .39) and two measures of poor psychosocial well-being, low level of hope and increased depression (r = -.42, r = .46). differences in contrasted means showed that teen girls who were abused by a partner reported higher scores for interpersonal violence. one-way anova showed that abused teen girls scored higher for interpersonal violence and depression but lower in hope. the internal consistency for the final total scale was .97 and .95 for physical/sexual abuse and .91 for the social/emotional abuse subscales. conclusions. results provide support for reliability and validity for the b
Psychometric Assessment of the Burgess-Partner Abuse Scale for Teens (B-PAST)
Stephanie E. Burgess,Abbas Tavakoli
Aquichán , 2005,
Abstract: Propósito. Evaluar las propiedades psicométricas de la Escala para adolescentes Burgués-Partner Abuse Scale (B-PAST), examinando la consistencia interna y validándola. Métodos. A una muestra de 239 ni as adolescentes, entre 13 y 19 a os, que formaron parte de la práctica privada y que aceptaron participar, se le aplicó dos medidas de violencia interpersonal, dos de bienestar psicoló- gico y un cuestionario demográfico. La validez fue valorada por 1) un factor de análisis de conducta exploratoria con una decisión a priori para retener dos factores, y 2) medición de la correlación diferencial de la violencia interpersonal y el bienestar psicosocial usando la correlación de Pearson. Con el fin de determinar la habilidad del instrumento para discriminar entre ni as que informaron abuso de sus compa eros y aquéllas que no lo informaron, se examinaron las diferencias de la media de los grupos (abusadas vs. no abusadas). Un ANOVA de una vía se utilizó para determinar las diferencias de la violencia interpersonal y el bienestar psicosocial. Se examinó la consistencia interna del B-PAST, estableciendo un criterio para el coeficiente alfa sobre .70. Resultados. El 70.9% de la variable se explicó por medio del B-PAST. El factor de análisis demostró una escala de 22 ítemes con dos subescalas diferentes. El B-PAST correlacionado con una medida de violencia interpersonal de los compa eros (r=.39) y dos medidas de bienestar psicosocial pobre, bajo nivel de esperanza y aumento de la depresión (r=-.42, r=.46). Las diferencias en los contrastes de la media mostraron que las ni as adolescentes que habían sido abusadas por un compa ero reportaron cifras más altas de violencia interpersonal. El ANOVA de una vía mostró que las ni as tenían cifras más altas para violencia interpersonal y depresión y bajas para esperanza. La consistencia interna para la escala total final fue de .97 y .95 para abuso físico/sexual y .91 para las subescalas de abuso social/emocional. Conclusión. Los resultados respaldan la confiabilidad y validez del B-PAST como una medida para el abuso entre compa eros en ni as adolescentes entre los 13 y 19 a os.
Moderate-Intensity Exercise Improves Body Composition and Improves Physiological Markers of Stress in HIV-Infected Men
Wesley David Dudgeon,Jason Reed Jaggers,Kenneth Doyle Phillips,John Larry Durstine,Stephanie E. Burgess,George William Lyerly,John Mark Davis,Gregory Alan Hand
ISRN AIDS , 2012, DOI: 10.5402/2012/145127
Abstract: HIV/AIDS and its treatment often alter body composition and result in poorer physical functioning. The aim of this study was to determine the effects of a moderate-intensity exercise program on body composition and the hormones and cytokines associated with adverse health outcomes. HIV-infected males ( ) were randomized to an exercise group (EX) who completed 6 weeks of moderate-intensity exercise training, or to a nonintervention control group (CON). In pre- and postintervention, body composition was estimated via DXA, peak strength was assessed, and resting blood samples were obtained. There was a decrease in salivary cortisol at wake ( ) in the EX and a trend ( ) for a decrease 1 hour after waking. The EX had a significant increase in lean tissue mass (LTM) ( ) following the intervention. Those in the EX below median body fat (20%) increased LTM ( ) only, while those above 20% decreased fat mass ( ), total fat ( ), and trunk fat ( ), while also increasing LTM ( ). Peak strength increased between 14% and 28% on all exercises in the EX group. These data indicate that 6 weeks of moderate-intensity exercise training can decrease salivary cortisol levels, improve physical performance, and improve body composition in HIV-infected men. 1. Introduction Over 33.3 million people are living with HIV-1 [1]. Since it was introduced in the mid to late 1990s, highly active antiretroviral therapy (HAART) has increased the time from HIV infection to acquired immunodeficiency syndrome (AIDS) diagnosis by 3 years and life expectancy of those with AIDS by up to 15 years [2]. In fact, these advances have allowed those living with HIV-1, and receiving treatment, to have life expectancies similar to uninfected persons with lifestyles that include smoking, heavy drinking, and obesity [3]. Mortality rates of HIV-infected persons dropped drastically within 18 months after the introduction of HAART, from 29.4 deaths per 100 person years to 8.8 deaths per 100 person years [4]. In fact, in younger (~30 years of age) persons with favorable disease markers (i.e., high CD4+ cell counts and low viral load) survival has been estimated at 31 years, with 45% of deaths attributable to non-HIV-related conditions, such as cardiovascular disease and cancer [5]. This brings about new challenges in treating persons with HIV-1, changing the focus from purely survival to improving quality of life by decreasing risk factors for other chronic conditions. Thus, it is important to understand how exercise training, which has been shown to be beneficial at reducing risk factors for both
Effect of Dietary EGCG on Normal and Vitamin E and Selenium Deficient Rats  [PDF]
Juan E. Andrade, John R. Burgess
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.48A020
Abstract: The tea catechin EGCG has been postulated to provide health benefits in humans, to some extent, as an antioxidant. The dose-response effect of dietary EGCG (0, 30, 60, or 120 mg/kg diet) was tested in rats under high versus low oxidative stress conditions that were created by feeding diets adequate in vitamin E and Se (Lox), or deficient in both (Hox) for six weeks. Effects on growth, quinone reductase (NQO1) activity, F2-isoprostanes and nutrient antioxidant amounts in the liver were evaluated as markers of nutrient deficiency and oxidative status. Under Hox conditions consumption of EGCG only at the lowest dose was partially associated with a protection against oxidative stress, reflected by a delay in growth deceleration, but no protection against lipid oxidation. Elevated liver NQO1 activity was observed in this group (>4-fold) increasing with the dose; but it was not associated with antioxidant protection. In contrast, under Lox conditions consumption of EGCG was associated with antioxidant activity reflected in a reduction (>30%) in F2-isoprostanes and protection of CoQ reduced status in the liver. Overall these results suggest that the antioxidant effect of EGCG in vivo depends on the level of oxidative stress and the presence of other nutrient antioxidants.
Automated DNA mutation detection using universal conditions direct sequencing: application to ten muscular dystrophy genes
Richard R Bennett, Hal E Schneider, Elicia Estrella, Stephanie Burgess, Andrew S Cheng, Caitlin Barrett, Va Lip, Poh Lai, Yiping Shen, Bai-Lin Wu, Basil T Darras, Alan H Beggs, Louis M Kunkel
BMC Genetics , 2009, DOI: 10.1186/1471-2156-10-66
Abstract: These factors have severely hampered diagnostic testing services, leaving many families without an answer for the exact cause of a familial genetic disease. A search of GeneTests for sequencing analysis of the entire coding sequence for genes that are known to cause muscular dystrophies returns only a small list of laboratories that perform comprehensive gene panels.The hypothesis for the study was that a complete set of universal assays can be designed to amplify and sequence any gene or family of genes using computer aided design tools. If true, this would allow automation and optimization of the mutation detection process resulting in reduced cost and increased throughput.An automated process has been developed for the detection of deletions, duplications/insertions and point mutations in any gene or family of genes and has been applied to ten genes known to bear mutations that cause muscular dystrophy: DMD; CAV3; CAPN3; FKRP; TRIM32; LMNA; SGCA; SGCB; SGCG; SGCD. Using this process, mutations have been found in five DMD patients and four LGMD patients (one in the FKRP gene, one in the CAV3 gene, and two likely causative heterozygous pairs of variations in the CAPN3 gene of two other patients). Methods and assay sequences are reported in this paper.This automated process allows laboratories to discover DNA variations in a short time and at low cost.This study focused on ten muscular dystrophy genes described in Online Mendelian Inheritance in Man [1], (Table 1); however the resulting process can be applied to any gene or family of genes.There are over 40 primary congenital muscle disorders (Additional file 1) determined now more by the defective genes causing the disorders rather than specific clinical descriptions. Many of these diseases are rare. The incidence, defined as the number of new cases per million live births, (or alternatively as the fraction of live births represented by one new case) is not known for many of the more rare diseases; nevertheless, th
BIOTECHNOLOGY IN THE STUDY OF PROTOZOAN PARASITES
Donald E. Burgess
Bulletin of Health Research , 2012,
Abstract: Over the past decade extraordinary advances have been made in the study of protozoan parasites. Particular progress has occurred in areas such as cultivation of protozoan parasites, immunobiology of protozoan parasitic diseases, the biochemistry of protozoa and molecular genetics of these organisms. The application of sophisticated culture, monoclonal antibody and recombinant DNA technologies has resulted in elucidation of many of the biochemical and molecular bases of such phenomena as antigenic variation in African trypanosomas, the autoimmune basis of the pathogenesis of Chagas' disease, protective immunity in malaria and parasite evasion of host defense mechanisms. As a result a new generation of diagnostic procedures have to provide more accurate detection of protozoan infections and thus improved epidemiological information. Vigorous vaccine development efforts are underway which will lead to molecularly defined vaccines taylored to specific applications and will provide new weapons to combat protozoan diseases. Perhaps most importantly the molecular bases of host-parasite interactions are being established and will allow identification of unique biochemical aspects of the biology of protozoa thereby revealing appropriate targets for development of vaccines, accurate detection procedures and more efficacious chemotherapeutic agents.
The properties and causes of rippling in quasi-perpendicular collisionless shock fronts
R. E. Lowe,D. Burgess
Annales Geophysicae (ANGEO) , 2003,
Abstract: The overall structure of quasi-perpendicular, high Mach number collisionless shocks is controlled to a large extent by ion reflection at the shock ramp. Departure from a strictly one-dimensional structure is indicated by simulation results showing that the surface of such shocks is rippled, with variations in the density and all field components. We present a detailed analysis of these shock ripples, using results from a two-dimensional hybrid (particle ions, electron fluid) simulation. The process that generates the ripples is poorly understood, because the large gradients at the shock ramp make it difficult to identify instabilities. Our analysis reveals new features of the shock ripples, which suggest the presence of a surface wave mode dominating the shock normal magnetic field component of the ripples, as well as whistler waves excited by reflected ions. Key words. Space plasma physics (numerical simulation studies; shock waves; waves and instabilities)
An Abdominal Presentation of Churg-Strauss Syndrome
J. R. E. Rees,P. Burgess
Case Reports in Medicine , 2010, DOI: 10.1155/2010/290654
Abstract: Churg-Strauss syndrome is a small and medium vessel vasculitis that is also known as allergic granulomatous angiitis. It most commonly presents with an asthma like symptoms. It was first described in Mount Siani Hospital, New York in 1951 by Jacob Churg and Lotte Stauss and was recognised after the study of a series of 13 patients who had asthma, eosinophilia, granulomatous inflammation necrotising systemic vasculitis and necrotising glomerulonephritis. We describe a case of Churg-Strauss syndrome presenting with abdominal pain and later during the hospital admission a mono-neuritis multiplex syndrome affecting the lower limbs. The patient presented in such an atypical fashion with abdominal signs and symptoms that they required laparotomy and the diagnosis was made after histological examination of tissue taken at the time of surgery. Treatment with immunosuppression and aggressive rehabilitation achieved a progressive recovery which continued on discharge from hospital.
The Impending Crisis
Raymond L. Kaplan,Thomas E. Burgess
Journal of Microbiology & Biology Education , 2010, DOI: 10.1128/jmbe.v11i2.230
Abstract: When you are ill and consult a physician for his or her expertise, many times laboratory testing is part of the clinical workup. This testing is critical to the physician's ability to diagnose the patient's condition. What if testing was not available ... because there was no one to do the testing? Although seemingly far-fetched, this scenario could play itself out in the next ten years due to an impending manpower crisis in laboratory medicine. The profession of Medical Technology, also known as Clinical Laboratory Science, is experiencing a shortage of qualified individuals for a variety of reasons - not the least of which is the closure of almost 70% of the schools teaching this critical profession. Health care workers (HCW) rely on accurate and timely clinical laboratory results in order to make decisions for their patients. Because ~ 70% of patient care decisions are based on clinical laboratory results, it is important to have a well-trained supply of laboratory professionals. This article will give an overview of the situation and the possible causes of this shortage, and pose challenges to our profession as to how this crisis can be averted. Visibility of this profession must be a prime focus of this effort in order for the population in general to be aware of the role Clinical Laboratory Scientists play in the health care consortium. This effort should begin early in the educational process, potentially as early as Middle School (junior high school), bringing awareness of the profession not only to students but to educators as well.
Biomarker Symptom Profiles for Schizophrenia and Schizoaffective Psychosis  [PDF]
Stephanie Fryar-Williams, J?rg E. Strobel
Open Journal of Psychiatry (OJPsych) , 2015, DOI: 10.4236/ojpsych.2015.51011
Abstract: Background: Neuroscience can assist clinical understanding and therapy by finding neurobiological markers for mental illness symptoms. Objectives: To quantify biomarkers for schizophrenia and schizoaffective disorder and relate these to discrete symptoms of psychosis. Methods: Within a case-control design with multiple exclusion criteria to exclude organic causes and confounding variables, 67 DSM IV-R diagnosed and 67 control participants from a defined hospital, clinic and community catchment area were investigated for candidate markers. Participants underwent protocol-based diagnostic-checking and symptom rating via Brief Psychiatric Rating Scale and Positive and Negative Syndrome Scale, functional-rating scales, biological sample-collection and sensory-processing assessment. Blood and urine samples were analysed for monoamine neurotransmitters, their metabolites, vitamin cofactors and intermediate-substances related to oxidative stress and metabolism of monoamines. Neurocognitive assessment of visual and auditory processing was conducted at both peripheral and central levels. Biomarkers were defined by Receiver Operating Curve (ROC) analysis. Spearman’s analysis explored correlations between discrete symptoms and the biomarkers. Results: Receiver Operating Curve (ROC) analysis identified twenty-one biomarkers: elevated urinary dopamine, noradrenaline, adrenaline and hydroxy pyrroline-2-one as a marker of oxidative stress. Other biomarkers were deficits in vitamins D, B6 and folate, elevation of serum B12 and free serum copper to zinc ratio, along with deficits in dichotic listening, distance vision, visual and auditory speed of processing, visual and auditory working memory and six middle ear acoustic reflex parameters. Discrete symptoms such as delusions, hostility, suicidality and auditory hallucinations were biomarker-defined and symptom biomarker correlations assumed an understandable pattern in terms of the catecholamines and their relationship to biochemistry, brain function and disconnectivity. Conclusions: In the absence of a full diagnosis, biomarker-symptom-signatures inform psychiatry about the structure of psychosis and provide an understandable pattern that points in the direction of a new neurobiological system of symptom-formation and treatment.
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