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Search Results: 1 - 10 of 6303 matches for " Stefano Filippi "
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Feasibility Evaluation of Integrating UsabilityEngineering Issues in a Design for Multi-XCollaborative Framework  [PDF]
Stefano Filippi
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.31004
Abstract: Design for manufacturing, design for assembly, and, in general, design for X, are methods helping an effective generation of industrial products. In parallel with the development of these methods, the research about usability engineering has generated many important results, both from the design, and the evaluation and testing points of view. The research described in this paper aims at evaluating the feasibility of the integration of two new usability methods, the design for innovative usability - DFIU -, and the integrated method for usability evaluation and testing - IMUET -, in an existing design for X named design guidelines collaborative framework - DGLs-CF -. Indeed, the DGLs-CF is a design for multi-X method, given that it covers both the manufacturing and the verification phases of the industrial product lifecycle. All these methods are currently under development by the author’s research group. To evaluate this feasibility, the first task of the research aims at describing and classifying the components of the three methods. Next, these components are semantically related to each other. Finally, the last activity verifies the compatibility between the components of the two usability methods and the data structures of the DGLs-CF to check the feasibility from the implementation point of view. The result of this research will consist of precise indications both for the development of a design for multi-X collaborative framework covering homogeneously the design, manufacturing, verification, and use phases of the industrial product lifecycle, and to be used as a reference for researchers interested in considering the integration of usability issues in their design tools, methods, and processes.
Using Rapid Prototyping Data to Enhance a Knowledge-Based Framework for Product Redesign  [PDF]
Stefano FILIPPI, Ilaria CRISTOFOLINI
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2010.21001
Abstract: The particular characteristics of Rapid Prototyping technologies, both in terms of constrains and opportunities, often require the reconfiguration of the product model to obtain the best compliance with the product functionalities and performances. Within this field of research, a knowledge-based tool named Design GuideLines Collaborative Framework (DGLs-CF) was developed to support both the designers defining the product consistently with the manufacturing technologies and the manufacturers defining the building setup consistently with the product requirements. Present work is focused on enhancing the DGLs-CF knowledge base and on updating the DGLs-CF knowledge management by using the information gathered on some RP technologies. The added-value of this research is represented by an improvement in the Redesign/Reconfig- uration Package, the final result of the DGLs-CF adoption. This is a list of actions to be performed on the product model and on the process parameters to avoid the limitations of the technology and to exploit at best its opportunities.
Classification and Selection of Prototyping Activities for Interaction Design  [PDF]
Stefano Filippi, Daniela Barattin
Intelligent Information Management (IIM) , 2012, DOI: 10.4236/iim.2012.44022
Abstract: Because of the evolution of markets and technologies, prototyping concerns should be kept updated almost day by day. Moreover, user centered design moves the focus towards interaction issues. Prototyping activities matching such characteristics are already available, but they are not so diffused in the industrial domain. This is due to many reasons; an important one is that a rigorous classification of them is missing, as well as an effective helping tool for the selection of the best activities, given the design context. The research described in this paper aims at defining a new classification of prototyping activities, as well as at developing a selection algorithm to choose the best ones in an automatic way. These goals are pursued by defining a set of characteristics that allow describing accurately the prototyping activities. The resulting classification is made by five classes, based on eighteen characteristics. This classification is exploited by the first release of an algorithm for the selection of the best activities, chosen in order to satisfy design situations described thanks to a different set of eleven indices. Five experiences in the field have been used up to now as a starting point for validating the research outcomes.
Mixed ab initio quantum mechanical and Monte Carlo calculations of secondary emission from SiO2 nanoclusters
Simone Taioli,Stefano Simonucci,Lucia Calliari,Massimiliano Filippi,Maurizio Dapor
Physics , 2009, DOI: 10.1103/PhysRevB.79.085432
Abstract: A mixed quantum mechanical and Monte Carlo method for calculating Auger spectra from nanoclusters is presented. The approach, based on a cluster method, consists of two steps. Ab initio quantum mechanical calculations are first performed to obtain accurate energy and probability distributions of the generated Auger electrons. In a second step, using the calculated line shape as electron source, the Monte Carlo method is used to simulate the effect of inelastic losses on the original Auger line shape. The resulting spectrum can be directly compared to 'as-acquired' experimental spectra, thus avoiding background subtraction or deconvolution procedures. As a case study, the O K-LL spectrum from solid SiO2 is considered. Spectra computed before or after the electron has traveled through the solid, i.e., unaffected or affected by extrinsic energy losses, are compared to the pertinent experimental spectra measured within our group. Both transition energies and relative intensities are well reproduced.
Search for genetic variants in the p66Shc longevity gene by PCR-single strand conformational polymorphism in patients with early-onset cardiovascular disease
Federica Sentinelli, Stefano Romeo, Fabrizio Barbetti, Andrea Berni, Emanuela Filippi, Marzia Fanelli, Mara Fallarino, Marco G Baroni
BMC Genetics , 2006, DOI: 10.1186/1471-2156-7-14
Abstract: We searched for sequence variations in the p66Shc specific region of the Shc gene and its upstream promoter by PCR-SSCP in a selected group of early onset coronary artery disease (CAD) subjects (n. 78, mean age 48.5 ± 6 years) and in 93 long-living control subjects (mean age 89 ± 6 years).The analysis revealed two variant bands. Sequencing of these variants showed two SNPs: -354T>C in the regulatory region of p66Shc locus and 92C>T in the p66 specific region (CH2). Both these variants have never been described before. The first substitution partially modifies the binding consensus sequence of the Sp1 transcription factor, and was detected only in two heterozygous carriers (1 CAD subjects and 1 control subject). The 92C>T substitution in the CH2 region consists in an amino acid substitution at codon 31 (proline to leucine, P31L), and was detected in heterozygous status only in one CAD subject. No subjects homozygous for the two newly described SNPs were found.Only two sequence variations in the p66Shc gene were observed in a total of 171 subjects, and only in heterozygotes. Our observations, in accordance to other studies, suggest that important variations in the p66Shc gene may be extremely rare and probably this gene is not involved in the genetic susceptibility to CAD.Increasing evidence indicates that reactive oxygen species (ROS) may participate in the pathogenesis of various diseases, including cardiovascular disorders. Support to this comes from the experimental demonstration that vessel walls of patients with atherosclerotic risk factors are characterized by a significant increase in vascular ROS production [1].It has been reported that the p66Shc longevity gene increases intracellular reactive oxygen species (ROS), thereby affecting the rate of oxidative damage to nucleic acids [2]. The human Shc locus (Src homologous and collagen) encodes three proteins with relative molecular masses of 46K (p46Shc), 52K (p52Shc) and 66K (p66Shc). All three proteins share a
Cristianismo y neoplatonismo en San Agustín: la crítica heideggeriana
Filippi,Silvana;
Enfoques , 2010,
Abstract: heidegger believes to find in st. augustine, as in the case of paul, the expression of human existence as a historic fact, and of history as non objectively or available fate. this radical facticity of self belongs to the christian earliest form of experience that appears with strong clearness in st. augustine's confessions, particularly in book x. there are two relevant aspects that stand out in the heideggerian reading of confessions: for one, the phenomenology of self, and secondly, the understanding of dasein as time. however, in st. augustine, the dramatic finitude of existence is metaphysically and theologically transcended and grounded; while in heidegger's reflection, the finitude of human existence tends to close itself on its own limits.
Gelassenheit: el desapego como forma de vida en la mística eckhartiana
Filippi,Silvana;
Enfoques , 2010,
Abstract: the notorious importance that eckhart gives to the detachment from things (gelassenheit) may suggest that the mystical german disdains active life. inversely, eckhart understands that the detachment in respect of the created being is perfectly compatible with the action and he even interprets the attitude of martha and mary towards jesus in a way which is opposite to the habitual.
Discursos en la ceremonia de entrega de la Medalla al Mérito Abate Juan Ignacio Molina a Guillermo Blanco: EL PERIODISTA GUILLERMO BLANCO
Emilio Filippi
Universum : Revista de Humanidades y Ciencias Sociales , 2005,
Abstract:
Martin heidegger y la mística eckhartiana
Silvana Filippi
Invenio , 2003,
Abstract: Esta exposición intenta poner de manifiesto cierta semejanza entre algunos aspectos de la mística eckhartiana y el pensamiento del último Heidegger. El propio pensador alemán ha aludido en más de una ocasión al místico medieval, evidenciando en su lenguaje y en el modo de presentar su pensamiento acerca del ser, la influencia que aquella tradición ha ejercido sobre él. Considerando, además que Heidegger intentaba eludir el discurso argumentativo característico de la metafísica, no resulta difícil conjeturar que el lenguaje místico de Meister Eckhart pudo constituir hasta cierto punto, un estilo de expresión alternativo, aun cuando el objeto y el fin de ambos pensadores fuesen diferentes
MODERN MR TECHNIQUES TO MONITOR THE EVOLUTION OF MULTIPLE SCLEROSIS
Massimo Filippi
Erciyes Medical Journal , 2002,
Abstract: Conventional magnetic resonance imaging (cMRI) is widely used for diagnosing multiple sclerosis (MS) and as a paraclinical tool to monitor disease activity and evolution in natural history studies and clinical trials. However, the correlation between cMRI and clinical findings is far from being strict. Among the reasons for this "clinical-MRI paradox", a major role has been attributed to the limited specificity of cMRI to the heterogeneous pathological substrates of MS and to its inability to quantify the extent of damage in the normalappearing tissues. Modern quantitative MR techniques have the potential to overcome some of the limitations of cMRI. Metrics derived from magnetization transfer and diffusion-weighted MRI enable us to quantify the extent of structural changes occurring within and outside macroscopic MS lesions with increased pathological specificity over cMRI. MR spectroscopy can add information on the biochemical nature of such changes, with the potential to improve significantly our ability to monitor inflammatory demyelination and axonal injury. Finally, functional MRI might provide new insights into the role of cortical adaptive changes in limiting the clinical consequences of white matter structural damage. Although the application of modern MR techniques is changing dramatically our understanding of how MS causes irreversible disability, their use for clinical trial monitoring is still very limited. Whereas there is increasing perception that modern quantitative MR techniques should be more extensively employed in clinical trials to advance the understanding of MS and derive innovative information, their use in clinical practice should still be regarded as premature.
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