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Search Results: 1 - 10 of 873 matches for " Stanciu Anca "
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Checkmate to liver biopsy in chronic hepatitis C?
Anca Trifan,Carol Stanciu
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i39.5514
Abstract: Liver biopsy (LB) has traditionally been considered the gold standard for pretreatment evaluation of liver fibrosis in patients with chronic hepatitis C (CHC). However, LB is an invasive procedure with several shortcomings (intra- and interobserver variability of histopathological interpretation, sampling errors, high cost) and the risk of rare but potentially life-threatening complications. In addition, LB is poorly accepted by patients and it is not suitable for repeated evaluation. Furthermore, the prevalence of CHC makes LB unrealistic to be performed in all patients with this disease who are candidates for antiviral therapy. The above-mentioned drawbacks of LB have led to the development of noninvasive methods for the assessment of liver fibrosis. Several noninvasive methods, ranging from serum marker assays to advanced imaging techniques, have proved to be excellent tools for the evaluation of liver fibrosis in patients with CHC, whereas the value of LB as a gold standard for staging fibrosis prior to antiviral therapy has become questionable for clinicians. Despite significant resistance from those in favor of LB, noninvasive methods for pretreatment assessment of liver fibrosis in patients with CHC have become part of routine clinical practice. With protease inhibitors-based triple therapy already available and substantial improvement in sustained virological response, the time has come to move forward to noninvasiveness, with no risks for the patient and, thus, no need for LB in the assessment of liver fibrosis in the decision making for antiviral therapy in CHC.
COLORECTAL CANCER SCREENING OF AVERAGE–RISK POPULATION FROM SUCEAVA COUNTY
Liliana Croitoru,Anca Trifan,C. Stanciu
Jurnalul de Chirurgie , 2010,
Abstract: Colorectal cancer (CRC) is the second leading cause of cancer death both in the USA and Europe. Although CRC is the most preventable visceral form of cancer, there is tremendous variation in screening practices around the world and most people do not have access to CRC screening. In Romania, the incidence of CRC has doubled during the last decade and despite evidence that CRC screening decreases CRC–related incidence and mortality only a minority of Romanians undergoes CRC screening. The aim of our study was to detect CRC and assess the feasibility of a fecal occult blood test (FOBT) – based screening program of average-risk population from Suceava County. From January 2006 to December 2009 invitations were sent to 1116 asymptomatic individuals aged ≥ 50 years from Suceava County. They were invited to an interview where a gastroenterologist suggested FOBT as a screening option. 546 (48.9%) subjects were interviewed and 521 agreed to a FOBT (Hemoccult SENSA); out of them, 501 have returned the tests for interpretation, so that the overall compliance was 44.9%. There were 48 (9.6%) subjects with FOBT positive and 43 (90%) of them accepted to undergo colonoscopy. Cancers and advanced adenomas (defined as adenomas ≥ 10 mm or histological high-degree dysplasia or villous component) were found in 5 (0.99%) and 11 (2.19%) subjects, respectively. The caecum was intubated in 40 (92%) colonoscopies, and the procedure was generally well tolerated without complications. In conclusion, a FOBT-based screening study for CRC in average-risk population from Suceava County was feasible, well accepted and safe in identifying a significant number of advanced neoplasms and cancers at a curable stage, suggesting the necessity of a national CRC screening in our country.
Experimental Research Concerning Mechanical Properties of Materials for Biomedical Use
Diana Cotoros,Anca Stanciu,Mihaela Baritz
Lecture Notes in Engineering and Computer Science , 2010,
Abstract:
Update on adrenal insufficiency in patients with liver cirrhosis
Anca Trifan,Stefan Chiriac,Carol Stanciu
World Journal of Gastroenterology , 2013, DOI: 10.3748/wjg.v19.i4.445
Abstract: Liver cirrhosis is a major cause of mortality worldwide, often with severe sepsis as the terminal event. Over the last two decades, several studies have reported that in septic patients the adrenal glands respond inappropriately to stimulation, and that the treatment with corticosteroids decreases mortality in such patients. Both cirrhosis and septic shock share many hemodynamic abnormalities such as hyperdynamic circulatory failure, decreased peripheral vascular resistance, increased cardiac output, hypo-responsiveness to vasopressors, increased levels of proinflammatory cytokines [interleukine(IL)-1, IL-6, tumor necrosis factor-alpha] and it has, consequently, been reported that adrenal insufficiency (AI) is common in critically ill cirrhotic patients. AI may also be present in patients with stable cirrhosis without sepsis and in those undergoing liver transplantation. The term hepato-adrenal syndrome defines AI in patients with advanced liver disease with sepsis and/or other complications, and it suggests that it could be a feature of liver disease per se, with a different pathogenesis from that of septic shock. Relative AI is the term given to inadequate cortisol response to stress. More recently, another term is used, namely “critical illness related corticosteroid insufficiency” to define “an inadequate cellular corticosteroid activity for the severity of the patient’s illness”. The mechanisms of AI in liver cirrhosis are not completely understood, although decreased levels of high-density lipoprotein cholesterol and high levels of proinflammatory cytokines and circulatory endotoxin have been suggested. The prevalence of AI in cirrhotic patients varies widely according to the stage of the liver disease (compensated or decompensated, with or without sepsis), the diagnostic criteria defining AI and the methodology used. The effects of corticosteroid therapy on cirrhotic patients with septic shock and AI are controversial. This review aims to summarize the existing published information regarding AI in patients with liver cirrhosis.
Microscopic Analysis of Breakage in Materials for Hard Implants
Cotoros Diana,Stanciu Anca,Baritz Mihaela,Cristea Luciana
Lecture Notes in Engineering and Computer Science , 2011,
Abstract:
Analysis of Bending Specific Deformation in Composite Materials Using Comparative Methods
Cotoros Diana,Stanciu Anca,Baritz Mihaela,Duta Violeta
Lecture Notes in Engineering and Computer Science , 2011,
Abstract:
Socio-economic factors and hygienic food-illness involved in determining dental caries of 12- year -old children in rural and urban
Cornel Gh. BOITOR,Anca FR??IL?,Liana STANCIU,Alina PITIC
Revista de Cercetare ?i Interven?ie Social? , 2011,
Abstract: Age of 12 is considered in most current research, reference age influencing both the incidence and intensity of dental caries and harmonious development of the dento - jaws of life of future periods. Two groups of students 12 years old, were studied, living in rural and urban areas, which were examined by a dentist and then they were questioned about the dental control method. The children’s parents were also asked to complete a questionnaire on maternal age at childbirth, mother’s education level, monthly family income, brushing supervision and control of children’s dentistry. The obtained data were registered in individual files and then centralized and statistically processed. Tags in rural areas have the following values: 89.6% caries frequency, intensity indicators DMF-T = 4.38, DMF-S = 9.11 and 6 year molars decayed percentage 69.44%. The values are the same indicators of urban decay rate 79.2%, DMF-T = 2.76, DMF-S = 5.69 and 6 year molars decayed percentage 30.55%. The study said that risk factors can act differently in rural areas where dental health problems are 1.48 higher than in urban areas. Regular dental check up, tooth brushing and effectively change your toothbrush every three months can significantly influence dental health at the age of 12 years in both environments.
HEAVY METALS ABUNDANCE IN THE SOILS OF THE PANTELIMON – BR NE TI AREA, ILFOV COUNTY a) CADMIUM, COBALT, CHROMIUM, COPPER
Radu Lacatusu,Mihaela Lungu,Mihaela Monica Stanciu Burileanu,Anca Rovena Lacatusu
Soil Forming Factors and Processes from the Temperate Zone , 2011,
Abstract: More than 20 years later, a new research on heavy metals (cadmium, cobalt, chromium, copper) contents in the soil cover of the Pantelimon – Br ne ti area located East of the Bucharest Municipality and exposed for several decades to the influence of industrial emissions from two non-ferrous metallurgy plants is presented. A 5,912.72 ha area was investigated, 544 samples taken by geometric horizons (0-20; 20-40; 40-60 cm) from 215 points have been analyzed.The dominant soils are: Preluvosols, Chernozems, Phaeozems. The analytical data showed that all the heavy metals contents are below the maximum allowable limits and of the alarm thresholds. Higher cadmium and copper concentrations have been registered in the 40-60 cm layer and higher chromium and copper concentrations in the 0-20 cm layer. Cadmium and cobalt distributions are non-central, with a right asymmetry, and the chromium and copper ones are slightly symmetric. The surface distribution of the heavy metals shows the presence of some high contents areas distributed insularly, with a higher frequency around the industrial units. The geochemical abundance indexes are higher than 1 for cadmium and lower for cobalt, chromium, and copper, and the pedo-geochemical abundance indexes are lower than 1 only for chromium.
The Univalence Conditions of Some Integral Operators
Laura Stanciu
Abstract and Applied Analysis , 2012, DOI: 10.1155/2012/924645
Abstract: We introduce new integral operators of analytic functions and defined in the open unit disk . For these operators, we discuss some univalence conditions.
PARTICULARITIES CONCERNING THE CREATION AND IMPLEMENTATION OF THE MARKETING MIX IN PUBLIC INSTITUTIONS
Sica STANCIU
Lex et Scientia , 2010,
Abstract: The marketing mix is the essential instrument in implementing marketing in the public sector. This paper brings into evidence the particularities of conceiving, elaborating and applying the marketing mix in public institutions. The particularities of the marketing mix that is applied in public institutions are imposed, on one hand, by the role played by the public institution and the place it occupies in the contemporary society and, on the other hand, by the objectives it defines by its marketing strategy. The tactic by which the marketing strategy is applied refers to the optimum combination of at least four controllable variables (service/product, tariff/price, distribution and promotion) accomplished by the public institution. The analysis of the classic marketing mix components – used in the public institution – allows the underlining of the significant aspects that improve the public institution activity, as well as its image in the future.
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