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Search Results: 1 - 10 of 6757 matches for " St?hr "
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Mich interessierten kostengünstige Alternativen zu Citavi“: über den Fortbildungsworkshop Literaturverwaltung im Fokus“ im Rahmen der AGMB-Tagung 2012 [“I was interested in competitive alternatives to Citavi”: About the workshop “Reference Management at the focal point”, held at the AGMB-Conference 2012]
Sthr, Matti
GMS Medizin-Bibliothek-Information , 2012, DOI: 10.3205/mbi000261
Abstract: [english] A two hour taking workshop on reference management, covering several software types, library services and more were part of the program at the AGMB-Conference 2012 in Aachen. This article is dealing less with the offered workshop contents itself. Moreover the attendees’ perspective is described. With an email-based survey the following main question wanted to be answered: Was the workshop fruitful for the participants? [german] Zum Programm der AGMB-Tagung 2012 in Aachen geh rte u.a. der zweistündige Fortbildungsworkshop Literaturverwaltung im Fokus – Softwaretypen, bibliothekarische Services und mehr“. Im Beitrag werden weniger die referierten Workshopinhalte beschrieben, als vielmehr die Perspektive der Teilnehmerinnen und Teilnehmer anhand einer eMail-basierten Umfrage vorgestellt. Die Kernfrage lautet hierbei: War der Workshop für sie gewinnbringend?
Literaturpropaganda als Bibliothekskultur. Ideologie und Wirklichkeit im ffentlichen Bibliothekswesen der frühen DDR
Matti Sthr
Libreas : Library Ideas , 2006,
Avian influenza and influenza pandemics
Lazzari Stefano,Sthr Klaus
Bulletin of the World Health Organization , 2004,
Creation of X-Ray Transparency of Matter by Stimulated Elastic Forward Scattering
Joachim Sthr,Andreas Scherz
Physics , 2015, DOI: 10.1103/PhysRevLett.115.107402
Abstract: X-ray absorption by matter has long been described by the famous Beer-Lambert law. Here we show how this fundamental law needs to be modified for high-intensity coherent x-ray pulses, now available at x-ray free electron lasers, due to the onset of stimulated elastic forward scattering. We present an analytical expression for the modified polarization-dependent Beer-Lambert law for the case of resonant core-to-valence electronic transitions and incident transform limited x-ray pulses. Upon transmission through a solid, the absorption and dichroic contrasts are found to vanish with increasing x-ray intensity, with the stimulation threshold lowered by orders of magnitude through a super-radiative coherent effect. Our results have broad implications for the study of matter with x-ray lasers.
Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain
Bettina Beyreuther, No?lle Callizot, Thomas Sthr
Arthritis Research & Therapy , 2007, DOI: 10.1186/ar2121
Abstract: Osteoarthritis is the most common form of joint disease and a leading cause of chronic pain and disability [1]. Its prevalence after age 65 is about 60% in men and 70% in women [2]. Osteoarthritis is primarily noted in hands, knees, hips, and spine and involves degeneration of articular cartilage as well as changes to the subchondral bone, variable degrees of mild synovitis and thickening of the joint capsule. Characteristic osteoarthritis features are seen in X-ray examination of joints. However, the pathophysiology behind the structural changes associated with this disease is complex and the link to pain is poorly understood [3].Pain is the predominant clinical feature, yet therapy is ineffective for many patients. Drugs that modify disease progression represent the ultimate goal of treatment but are not clinically available. Treatment is currently based on symptomatic relief of pain and inflammation associated with osteoarthritis to increase joint function. Non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are the most widely used drugs but cyclooxygenase 2 inhibitors, steroids, and opiates are prescribed as well [4].Several arthritis animal models have been established [5]. One of the best characterized rat models for analyzing properties of drugs on the pathology of osteoarthritis is the injection of the metabolic inhibitor monosodium iodoacetate (MIA) into the joint, which inhibits the activity of glyceraldehyde-3-phosphate dehydrogenase in chondrocytes, resulting in disruption of glycolysis and eventually in cell death [6,7]. The progressive loss of chondrocytes results in histological and morphological changes of the articular cartilage, closely resembling those seen in osteoarthritis patients. However, analysis of pain behavior has only recently been established in the iodoacetate model [8-11]. In a previous study the anticonvulsant gabapentin was able to reduce secondary mechanical allodynia but not hyperalgesia in the iodoacetate rat model
Power, knowledge, and conflict in the shaping of commons governance. The case of EU Baltic fisheries
Tom R. Burns,Christian Sthr
International Journal of the Commons , 2011,
Abstract: This article aims at contributing to governance conceptualization and its application to case study analyses. Two of the challenges which the theoretical and empirical work in the article addresses concern the facilitation of comparability of diverse governance cases and a specification of several key mechanisms of governance formation and reform. A proposed model of the architecture of governance systems – their major components and inter-linkages – contributes, as argued and illustrated here, to greater comparability among cases and with the possibility of improved accumulation of knowledge about governance systems. These tools are applied to empirical cases of governance structure and their functioning and reformation. Baltic fisheries, a complex, multi-level case of commons governance, is considered in some detail in order to illustrate and elaborate the key factors of power, knowledge, and conflict in the functioning and transformation of governance systems. In addition to the Baltic fisheries case, we consider briefly for comparative purposes chemicals and gender relations as additional areas of EU governance. The paper is divided into four sections. Section I introduces the basic conceptualization and tools of analysis. Section II presents the case of Baltic fisheries. Section III elaborates the key concepts and tools presented in Section I, in particular considering additional cases of the functioning of governance systems. Section IV is a brief conclusion.
Upper bounds for the dimension of moduli spaces of curves with symmetric Weierstrass semigroups
André Contiero,Karl-Otto Sthr
Mathematics , 2012, DOI: 10.1112/jlms/jdt034
Abstract: We present an explicit method to produce upper bounds for the dimension of the moduli spaces of complete integral Gorenstein curves with prescribed symmetric Weierstrass semigroups.
Global Diversity of Brittle Stars (Echinodermata: Ophiuroidea)
Sabine Sthr,Timothy D. O'Hara,Ben Thuy
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031940
Abstract: This review presents a comprehensive overview of the current status regarding the global diversity of the echinoderm class Ophiuroidea, focussing on taxonomy and distribution patterns, with brief introduction to their anatomy, biology, phylogeny, and palaeontological history. A glossary of terms is provided. Species names and taxonomic decisions have been extracted from the literature and compiled in The World Ophiuroidea Database, part of the World Register of Marine Species (WoRMS). Ophiuroidea, with 2064 known species, are the largest class of Echinodermata. A table presents 16 families with numbers of genera and species. The largest are Amphiuridae (467), Ophiuridae (344 species) and Ophiacanthidae (319 species). A biogeographic analysis for all world oceans and all accepted species was performed, based on published distribution records. Approximately similar numbers of species were recorded from the shelf (n = 1313) and bathyal depth strata (1297). The Indo-Pacific region had the highest species richness overall (825 species) and at all depths. Adjacent regions were also relatively species rich, including the North Pacific (398), South Pacific (355) and Indian (316) due to the presence of many Indo-Pacific species that partially extended into these regions. A secondary region of enhanced species richness was found in the West Atlantic (335). Regions of relatively low species richness include the Arctic (73 species), East Atlantic (118), South America (124) and Antarctic (126).
Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
Jelena Stojic, Heidi Sthr, Bernhard HF Weber
BMC Molecular Biology , 2007, DOI: 10.1186/1471-2199-8-42
Abstract: Two additional exons within intron 5 of the ABCC5 gene were identified; one of the exons exhibits alternative donor splice sites. Differential usage of these exons generates three short ABCC5 transcripts named ABCC5_SV1, ABCC5_SV2 and ABCC5_SV3. The variants share the first five exons with the ABCC5 gene but differ in their 3' sequences. ABCC5 and its novel isoforms are abundantly expressed in the human retina. Splice variant ABCC5_SV1 and ABCC5_SV2 contain premature stop codons. While inhibition of nonsense-mediated mRNA decay selectively stabilized ABCC5_SV1 but not ABCC5_SV2, the amount of full length ABCC5 mRNA was simultaneously reduced. A negative regulatory effect on full length ABCC5 expression was also observed when the ABCC5 isoforms were silenced with siRNA duplexes. Finally, we show that the evolutionarily conserved ABCC5_SV2 transcript is translated into a protein abundantly present in endothelial cells of inner retinal blood vessels and along RPE membranes.Our data suggest that alternative splicing of the ABCC5 gene has functional consequences by modulating ABCC5 gene expression. In addition, at least one ABCC5 splice variant is protein-coding and produces a truncated ABCC5 protein isoform with thus far unknown functional properties in the retina.ATP-binding cassette (ABC) transporters are integral membrane proteins which mediate the ATP-dependent translocation of a wide variety of compounds across extra- and intracellular membranes [1]. The substrate diversity ranges from small inorganic ions, amino acids, peptides, sugars, lipids, and anticancer drugs to large proteins. ABC transporters are characterized by a basic modular architecture consisting of two membrane spanning segments and two intracellular nucleotide binding domains with Walker motifs A and B and an ATP-binding cassette signature [1].Based on protein sequence homology and phylogenetic analyses, the 56 mammalian ABC transporters have been classified into seven subfamilies with the closely
Fibration by non-smooth projective curves of arithmetic genus two in characteristic two
Alejandro Simarra Ca?ate,Karl-Otto Sthr
Mathematics , 2014,
Abstract: Looking in positive characteristic for failures of the Bertini-Sard theorem, we determine, up to birational equivalence, the separable proper morphisms of smooth algebraic varieties in characteristic two, whose fibres are non-smooth curves of arithmetic genus two.
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