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Search Results: 1 - 10 of 6108 matches for " Stéphanie Bocs "
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Re-annotation of genome microbial CoDing-Sequences: finding new genes and inaccurately annotated genes
Stéphanie Bocs, Antoine Danchin, Claudine Médigue
BMC Bioinformatics , 2002, DOI: 10.1186/1471-2105-3-5
Abstract: We have developed a new program that automatically identifies biologically significant candidate genes in a bacterial genome. Twenty-six complete prokaryotic genomes were analyzed using this tool, and the accuracy of gene finding was assessed by comparison with existing annotations. This analysis revealed that, despite the enormous effort of genome program annotators, a small but not negligible number of genes annotated within the framework of sequencing projects are likely to be partially inaccurate or plainly wrong. Moreover, the analysis of several putative new genes shows that, as expected, many short genes have escaped annotation. In most cases, these new genes revealed frameshifts that could be either artifacts or genuine frameshifts. Some entirely unexpected new genes have also been identified. This allowed us to get a more complete picture of prokaryotic genomes. The results of this procedure are progressively integrated into the SWISS-PROT reference databank.The results described in the present study show that our procedure is very satisfactory in terms of gene finding accuracy. Except in few cases, discrepancies between our results and annotations provided by individual authors can be accounted for by the nature of each annotation process or by specific characteristics of some genomes. This stresses that close cooperation between scientists, regular update and curation of the findings in databases are clearly required to reduce the level of errors in genome annotation (and hence in reducing the unfortunate spreading of errors through centralized data libraries).The main goal of large-scale genome sequencing projects is to obtain new insights into physiological and biological processes underlying the very organization of life. An essential step in this quest is gene identification, with subsequent functional annotation of the corresponding gene products. Gene recognition in bacteria is far from being always straightforward, despite the fact that bacterial g
Mechanisms of haplotype divergence at the RGA08 nucleotide-binding leucine-rich repeat gene locus in wild banana (Musa balbisiana)
Franc-Christophe Baurens, Stéphanie Bocs, Mathieu Rouard, Takashi Matsumoto, Robert NG Miller, Marguerite Rodier-Goud, Didier MBéguié-A-MBéguié, Nabila Yahiaoui
BMC Plant Biology , 2010, DOI: 10.1186/1471-2229-10-149
Abstract: Sequence comparison revealed two regions of contrasting features. The first is a highly colinear gene-rich region where the two haplotypes diverge only by single nucleotide polymorphisms and two repetitive element insertions. The second corresponds to a large cluster of RGA08 genes, with 13 and 18 predicted RGA genes and pseudogenes spread over 131 and 152 kb respectively on each haplotype. The RGA08 cluster is enriched in repetitive element insertions, in duplicated non-coding intergenic sequences including low complexity regions and shows structural variations between haplotypes. Although some allelic relationships are retained, a large diversity of RGA08 genes occurs in this single M. balbisiana genotype, with several RGA08 paralogs specific to each haplotype. The RGA08 gene family has evolved by mechanisms of unequal recombination, intragenic sequence exchange and diversifying selection. An unequal recombination event taking place between duplicated non-coding intergenic sequences resulted in a different RGA08 gene content between haplotypes pointing out the role of such duplicated regions in the evolution of RGA clusters. Based on the synonymous substitution rate in coding sequences, we estimated a 1 million year divergence time for these M. balbisiana haplotypes.A large RGA08 gene cluster identified in wild banana corresponds to a highly variable genomic region between haplotypes surrounded by conserved flanking regions. High level of sequence identity (70 to 99%) of the genic and intergenic regions suggests a recent and rapid evolution of this cluster in M. balbisiana.Comparative genomics studies at the interspecies and intraspecies levels have revealed the dynamics of genome evolution and the plasticity of plant genomes. Within monocotyledons, the grass species of the order Poales have been extensively studied for their genome structure and evolution [1], but little is known about monocotyledon plants outside this group. Musa species are giant herbs from the
Emotion Regulation, Personality and Social Adjustment in Children with Autism Spectrum Disorders  [PDF]
Nathalie Nader-Grosbois, Stéphanie Mazzone
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.515182
Abstract: The study examines how emotion regulation and emotion dysregulation in 3 - 12 years old children with autism spectrum disorders (n = 39) are linked with the five factors of personality and their social adjustment. Children were assessed by means of the Differential Scales of Intellectual Efficiency-Revised edition (EDEI-R). The teachers have completed the CARS-T, the Bipolar Rating Scales based on the Five Factor Model (EBMCF) and the French version of Emotion Regulation Checklist (ERC-vf) and a Social Adjustment scale (including items related to Theory of Mind, EASE-ToM, and related to social rules, EASE-Social-Skills). Positive and significant correlations are obtained between emotion regulation scores and verbal developmental age, personality factors of openness, agreeableness, and extraversion. The emotion dysregulation score is negatively and significantly linked with the factor of emotional stability, but positively and significantly linked with extraversion. Moreover, emotion regulation scores are positively and significantly linked with scores in social adjustment. Linear regression by stepwise shows that both extraversion and agreeableness explain 66.5% of the variance of the emotion regulation score; and extraversion, agreeableness and emotional stability explain 68.3% of the variance of the emotion dysregulation score. The openness explains 55.9% of the variance of the EASE-ToM score. Both agreeableness and extraversion explain 61.6% of the variance of the EASE-Social Skills score.
How Are Parental Reactions to Children’s Emotions Related to Their Theory of Mind Abilities?  [PDF]
Stéphanie Mazzone, Nathalie Nader-Grosbois
Psychology (PSYCH) , 2016, DOI: 10.4236/psych.2016.72019
Abstract: In this study, parents’ reactions to their children’s emotions were investigated as correlates of children’s abilities in Theory of Mind (ToM). 175 parents completed questionnaires about their reactions to their children’s emotions. Children’s ToM abilities were assessed by direct measures and a questionnaire completed by mothers. Inter-parental comparisons and intra-parental inter-actions were explored. The maternal model was significant for children’s ToM-emotions and ToM-thinking. The paternal model was significant for children’s ToM-beliefs. Maternal supportive reactions (SR) to positive emotions were related to children’s ToM-emotions and ToM-thinking. Moreover, maternal non-supportive reactions (NSR) to negative emotions were negatively associated with children’s ToM-thinking. The interaction between paternal SR to children’s positive emotions and a low level of NSR to positive emotions was associated with a high level of ToM-beliefs. The results suggest that exploring the parental gender effect and the combined effects of parental reactions is useful for understanding children’s ToM development.
Emotion-Related Socialization Behaviours in Parents of Children with an Autism Spectrum Disorder  [PDF]
Stéphanie Mazzone, Nathalie Nader-Grosbois
Psychology (PSYCH) , 2017, DOI: 10.4236/psych.2017.88074
Abstract: Eisenberg, Cumberland and Spinrad (1998) defined Emotion-Related Socialization Behaviours (ERSBs) as parents’ behaviours that tend to promote their children’s emotional and social abilities. They distinguish three types of ERSBs in parents: their reactions to their children’s emotions, their emotion-related conversations and their emotional expressiveness. The two present studies compare these reactions (Study 1) and conversations (Study 2) in parents of children with an Autism Spectrum Disorder (ASD) and parents of typically developing (TD) children. Moreover, by applying several linear regression analyses by the stepwise method, they examined the extent to which such ERSBs vary according to individual characteristics in children and parents. Study 1 included 39 mothers and 31 fathers of ASD children and 39 mothers and 31 fathers of TD children. In Study 2, 29 mothers and 15 fathers of ASD children and 29 mothers and 15 fathers of TD children participated. For the two studies, children were matched for gender and global developmental age. Parents’ ERSBs, their openness to emotional processes and children’s personality were assessed by means of questionnaires. Children’s developmental age was assessed using the Differential Scales of Intellectual Efficiency. For each study, we considered mothers and fathers independently in our analyses, with a view to adapt parenting programmes for each parent if necessary. Results revealed that there are few differences between the two groups of parents in their ERSBs. Regression analyses showed that the variance in ERSBs in parents of ASD children was explained partially by their openness to emotional processes and by their children’s personality. Our results suggest that, although parents of ASD children are good “socializers of emotions”, intervention programs should take account of the fact that their ERSBs vary according to their own emotional abilities and their children’s personality. These studies emphasize the importance of identifying which individual characteristics are protective or risk factors for parent’s behaviours.
Variability and Predictors of Mothers and Fathers’ Socialization Behaviors and Bidirectional Links with Their Preschoolers Socio-Emotional Competences  [PDF]
Stéphanie Mazzone, Nathalie Nader-Grosbois
Journal of Behavioral and Brain Science (JBBS) , 2017, DOI: 10.4236/jbbs.2017.712043
Abstract: In their Parental Socialization of Emotions model, Eisenberg, Cumberland and Spinrad (1998) differentiated parents’ Emotion-Related Socialization Behaviours (ERSBs) that support their child’s socio-emotional development: their reactions to their child’s emotions, their discussions about emotions with the child and the expressions of their own emotions in the family. The cross- sectional study focused on the variability of parents’ ERSBs according to children’s and parents’ characteristics (Study 1) and included 167 mothers and 152 fathers of preschoolers. The short-term longitudinal study examined the interaction between parents’ ERSBs and children’s socio-emotional abilities (Theory of Mind, emotional regulation and social adjustment) (Study 2) in 53 two-parent families and their children, with a 6 months interval. In Study 1, parents’ ERSBs, their emotional competences and children’s personality were assessed by means of questionnaires. In Study 2, we combined direct and indirect measures to assess children’s socio-emotional competences. Results of Study 1 indicated that parental ERSBs were mainly predicted by children’s personality, such as emotional stability and parents’ emotional competences, such as communication about their own emotions. Moreover, we observed a differential sensitivity between mothers and fathers toward children’s personality. Results of Study 2 revealed that both mothers and fathers socialized their children’s socio-emotional competences, particularly by the way of emotion-related conversations with their children. Mothers’ emotion-related conversations predicted children’s Theory of mind abilities and social adjustment, while fathers’ emotion-related conversations predicted children’s emotional regulation. In addition, fathers’ reactions to their children’s emotions were predicted by children’s socio-emotional competences. These studies highlighted bidirectional effects between parents’ behaviours and children’s development. They emphasized also the importance to better identify predictors of parents’ ERSBs in order to know on which target the professionals should intervene.
Theoretical and Methodological Contributions of a Multi-Situated Approach and the Analysis of Migration Routes: The Example of Migration between Morocco and Canada
Garneau, Stéphanie;
Frontera norte , 2010,
Abstract: based on a series of research results on moroccan migration to canada, this paper seeks to prove how focusing on the migration routes of a specific national group of migrants and using a multi-situated methodological approach will not lead to the "ethnisizing", culturalizing or nationalizing of the experienced realities, but rather to the placing of actions within their political, cultural, social and economic structuring contexts. by resorting to an inductive approach, this perspective allows us to identify frontiers (in a symbolic sense) other than cultural or national belonging, reminding us of the internal heterogeneity of the studied national group, allowing us to apprehend other decisive factors in the migration route, and favoring our understanding of the plurality of the space practices and integration strategies developed by social actors when facing the concrete opportunities and limitations found during the whole migration process.
Transnacionalización de la subsistencia familiar: El caso de los refugiados colombianos en Quebec
Arsenault, Stéphanie;
Migraciones internacionales , 2009,
Abstract: the movement of money between the province of quebec and colombia is managed primarily by relatives, usually for the purpose of daily family subsistence. the monetary flows between these places occur within heart of the families, their frequency is highly variable, and the amounts involved are modest. statements gathered from people who send money to relatives in colombia reveal that for most, the frequency and the amount sent diminish once the person has settled in quebec when compared to the situation prior to exile. for many, their role as the family's economic provider has declined considerably, and for some, it has entirely ceased. generally, we can assert that people do not make major changes in their intention to help their families economically once they have left colombia. instead, the changes arise from their specific ability to do so, which declines or disappears altogether.
Las políticas de salud reproductiva en el Perú: reformas sociales y derechos ciudadanos
Rousseau, Stéphanie;
Revista Estudos Feministas , 2007, DOI: 10.1590/S0104-026X2007000200003
Abstract: the article analyzes the case of reproductive health policy-making in peru in the context of recent social policy reforms. health-sector reforms have only partially redressed peruvian women's unequal access to family planning, reproductive rights and maternal care. the main sources of inequalities are related to the segmented character of the health-care system, with the highest burden placed on the public sector. the majority of women from popular classes, who are not protected by an insurance plan, are dependent upon what and how public services are provided. simultaneously, the continuing role of conservative sectors in public debates about reproductive health policy has a strong impact on public family planning services and other reproductive rights.
Caracterización de un acuífero kárstico por sísmica de reflexión de alta resolución
KLARICA,STéPHANIE;
Revista de la Facultad de Ingeniería Universidad Central de Venezuela , 2006,
Abstract: the present study was carried out in the pyrenean foothills (southwest of france) and shows a good application of high resolution seismic reflection to the knowledge of the first hundred meters of the subsurface. we have clearly characterized a karstic aquifer localized in the old glacial valley of ossau. all measurements were registered with a 24 channels seismograph, a sledgehammer stroked on a metallic plate or a shotgun and 24 vertical geophones. the processing of the seismic reflection data follows a traditional sequence: the signals were initially processed with frequency filters, fk filters and deconvolution; finally, a depth seismic migrated section was created. the subsurface coverage of the acquisition scheme and the complete processing sequence allowed us to produce seismic sections of high quality which show reflexions down to 200m depth. the geometric and geological context where the oasis springs emerge is now clearly defined. the springs are encountered in this part of the ossau valley because of the near outcrop of the upper aptien limestones. additionally, the lock of the glacial formed by the north pyrenean fault, represents an insuperable border that allow the oasis springs to emerge.
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