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Search Results: 1 - 10 of 18952 matches for " Srinivasa U "
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Srinivasa U,Amrutia Jay N,Katharotiya Reena,Moses Semuel Rajan
International Research Journal of Pharmacy , 2011,
Abstract: Petroleum ether, chloroform, methanol and aqueous extracts of leaves of Moringa oleifera were screened for various bioactive constituents like glycosides, carbohydrates, tannins, flavonoids, triterpenoids and alkaloids. The chloroform and methanol extracts were evaluated for anthelmintic activity on adult Indian earthworms Pheritima postuma using Piperazine citrate and Rajah Pravartani Vati (Ayurvedic preparation) as a reference standards. The results obtained indicated that the chloroform extract was more potent compared to other extracts.
Amrutia Jay N,Lala Minaxi,Srinivasa U.,Shabaraya A. R.
International Research Journal of Pharmacy , 2011,
Abstract: Moringa oleifera which is commonly known as drumstick tree has been used for its nutrition value and extensively used as a CNS depressant traditionally. Present work has been carried out to evaluate the anticonvulsant activity of methanolic extract of M. oleifera leaves against pentylenetetrazole (PTZ) and maximal electroshock (MES) induced convulsions at different dose level (200 mg/kg and 400 mg/kg i.p.). Diazepam and phenytoin (5mg/kg i.p. and 25mg/kg i.p., respectively) were used as a reference standard. At both the doses it significantly (P < 0.0001) delayed the onset of clonic seizures in PTZ induced convulsions and significantly reduced (P < 0.0001) duration of hind limb extension in MES test. The phytochemical investigation of plant revealed the presence of alkaloids, flavonoids, tannins and saponins as major constituents. The data obtained indicates that methanolic extract of M. oleifera leaves may help to control grand mal and petit mal epilepsy.
The effects of climatic factors on the distribution and abundance of Japanese encephalitis vectors in Kurnool district of Andhra Pradesh, India
U. Suryanarayana Murty, M. Srinivasa Rao , N. Arunachalam,N. Arunachalam
Journal of Vector Borne Diseases , 2010,
Abstract: Background & objectives: Climatic attributes have been associated with relative mosquito abundanceand transmission of mosquito borne infections in many parts of the world, especially in warm andtropical climatic regions. The main objectives of this study were to assess the change in seasonalpattern of Japanese encephalitis (JE) vectors, their density, to elucidate whether the lagged climatevariables (precipitation, temperature and humidity) are associated with JE vector density, and todetermine if temperature and precipitation are similarly important for the rise in the number ofpotential mosquito vectors for JE virus in the temperate climate of Andhra Pradesh, India.Methods: Mosquito samples were collected from Kurnool district of Andhra Pradesh using handcatch and light-trap methods during 2002 to 2006. The type and abundance of recovered specieswere compared to ecological correlates. In each geographic area, temperature and precipitationare the two possible proxy variables for mosquito density, in conjunction with other seasonalfactors for JE epidemics.Results: Out of the various mosquito species collected, Culex gelidus and Cx. tritaeniorhynchuswere noticed in high numbers. There was considerably high prevalence of Cx. gelidus (68.05%) inurban area than in rural areas whereas, Cx. tritaeniorhynchus (57.51%) was found to be more inrural areas than in the urban area. It is noticed that the factors such as rainfall and temperaturewere found to be correlated with the per man hour (PMH) density, whereas the humidity wasinversely correlated with the PMH.Interpretation & conclusion: The environmental and eco-climatic factors are assisting in enhancingthe breeding of these mosquitoes in Kurnool district of Andhra Pradesh, India. Both Cx.tritaeniorhyncus and Cx. gelidus are quite adaptable to these environmental conditions and thisnecessitates immediate control measures in both rural and urban areas of Kurnool district.
Increased chickpea yield and economic benefits by improved crop production technology in rainfed areas of Kurnool district of Andhra Pradesh, India
A Ramakrishna,SP Wani,Ch Srinivasa Rao,U Srinivas Reddy
Journal of SAT Agricultural Research , 2005,
Abstract: Sixteen on-farm trials in 2002 and 9 trials in 2003 were conducted during the post-wet season in Kurnool, Andhra Pradesh, India, to demonstrate the beneficial effects of improved production technologies over farmers' practice. The improved technology package included improved chickpea cv. ICCC 37, a seed rate of 60 kg/ha, seed treatment with thiram (3 g/kg seed), inoculation with Rhizobium, a fertilizer dose of 20 kg N and 50 kg P/ha, basal application of micronutrient mixture of 0.5 kg B, 10 kg Zn and 30 kg S/ha, together with need-based pest and disease control measures. The farmers' method included a local cultivar, a seed rate of 50 kg/ha and a fertilizer dose of 14 kg N and 35 kg P/ha. The improved production technology gave higher grain yield and recorded a mean yield of 2.09 t/ha, which was 53% higher than that obtained with farmers' practice yields of 1.37 t/ha. The increased grain yield with improved production technology was mainly because of increased total dry matter, higher 100-grain weight and harvest index. An additional cost of $56/ha incurred in the improved technology compared to farmers' practice was mainly due to balanced fertilizer application (micronutrients and additional N and P), additional seed cost, seed treatment, integrated pest management and one additional intercultivation. However, the improved technology increased the mean income to $190 with a cost benefit ratio of 2.9
Effect of improved crop production technology on pigeonpea yield in resource poor rainfed areas
A Ramakrishna,SP Wani,Ch Srinivasa Rao,U Srinivas Reddy
Journal of SAT Agricultural Research , 2005,
Abstract: Twelve on-farm trials were conducted during the 2002/03 wet season in Andhra Pradesh, India, to study the effect of improved production technologies over farmers' practice. The improved technology package included medium duration high-yielding cv. ICPL 87119, resistant to Fusarium wilt and sterility mosaic disease [Pigeon pea sterility mosaic virus]; seed rate of 12 kg/ha; seed treatment with thiram (3 g/kg seed); inoculation with Rhizobium; 20 kg N and 50 kg P/ha; basal application of 0.5 kg B, 10 kg Zn and 30 kg S/ha together with appropriate need-based pest and disease control measures. The farmers' method included a seed rate of 10 kg/ha and basal application of 12 kg N and 30 kg P/ha. The improved production technology gave the highest total dry matter (5.26 t/ha), pod weight (2.33 t/ha), shelling percentage (69.1%), 100-grain weight (10.3 g) and harvest index (0.31)
Headache In Children
Srinivasa R
Annals of Indian Academy of Neurology , 2002,
Abstract: Headaches are common in children. The presentation of headache in children is varied and hence the characterization of headache is more challenging. This situation is worsened further by inadequacies in the history and the effect of maturational factors. Relevant epidemiological and limitations in the applicability of International Headache Society criteria in childhood headache and the rationale for newer criteria are discussed. Migraine and tension-type headache are the common primary headache seen in children. Although there is a paucity of clinical trials the management of childhood migraine, the important role of correct pharmacological approach has been delineated. The pivotal role of non-pharmacological treatment is emphasized.
Self-Oscillating Structural Polymer Gels  [PDF]
Srinivasa R. Pullela, Qingsheng Wang, Zhengdong Cheng
Advances in Nanoparticles (ANP) , 2013, DOI: 10.4236/anp.2013.22016
Abstract: self-oscillating polymer gel has become a distinguished class of smart soft materials. Here we fabricated and demonstrated a self-oscillating structural gel network with the incorporation of the Belousov-Zhabotinsky (BZ) reaction. The structural polymer gel oscillates at a macroscopic level with remarkably faster kinetics compared to a normal gel of similar chemical compositions. The structural polymer gel also displays larger oscillating amplitude compared to the normal gel because of the increased diffusion of fluids surrounding the gel particles. This type of structural polymer gels can be harnessed to provide novel and feasible applications in a wide variety of fields, such as drug delivery, nanopatterning, chemical and biosensing, and photonic crystals.

Ultra-Low Power Designing for CMOS Sequential Circuits  [PDF]
Patikineti Sreenivasulu, Srinivasa Rao, Vinaya Babu
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2015, DOI: 10.4236/ijcns.2015.85016
Abstract: Power consumption is the bottleneck of system performance. Power reduction has become an important issue in digital circuit design, especially for high performance portable devices (such as cell phones, PDAs, etc.). Many power reduction techniques have also been proposed from the system level down to the circuit level. High-speed computation has thus become the expected norm from the average user, instead of being the province of the few with access to a powerful mainframe. Power must be added to the portable unit, even when power is available in non-portable applications, the issue of low-power design is becoming critical. Thus, it is evident that methodologies for the design of high-throughput, low-power digital systems are needed. Techniques for low-power operation are shown in this paper, which use the lowest possible supply voltage coupled with architectural, logic style, circuit, and technology optimizations. The threshold vol-tages of the MTCMOS devices for both low and high Vth are constructed as the low threshold Vth is approximately 150 - 200 mv whereas the high threshold Vth is managed by varying the thickness of the oxide Tox. Hence we are using different threshold voltages with minimum voltages and hence considered this project as ultra-low power designing.
Fast and Accurate Identification of M. tuberculosis Complex Using an Immunochromatographic MPT64 Antigen Detection Test  [PDF]
Anto Jesuraj Uday Kumar, Hiresave Srinivasa
Journal of Tuberculosis Research (JTR) , 2015, DOI: 10.4236/jtr.2015.34021
Abstract: Background: A new rapid Immunochromatographic test (ICT) kit (MPT64 TB Ag Kit) for detection of MPT64 Antigen in M. tuberculosis (MTB) isolates used for rapid identification of MTB isolates developed by SD (Standard Diagnostics) Bio line, South Korea was evaluated. The ICT is a rapid, reliable and cheaper method that can be used instead of conventional biochemical tests for confirming MTB in culture isolates in resource limited laboratories. The study also evaluated the ability of ICT to detect MPT64-Antigen before the micro MGIT could signal positive. Material/Methods: A total of 450 sputum samples of individual patients were used for the study. 152 isolates of Mycobacteria were recovered from solid and liquid media. These strains were tested for the detection of MPT64-antigen. H37Rv strain was served as the positive reference control and also used for early detection of Antigen experiment. Findings: The development of bands on both test and sample region when H37Rv strain was tested were seen (MPT64 antigen positive). When 138 MTB isolates were tested, it showed a similar banding pattern indicating 100% sensitivity. MPT64 band formation was not detected in any of the 14 isolates indicating 100% specificity. Both PPV & NPV were 100%. All the isolates negative for MPT64 Ag were confirmed as MOTT by conventional bio-chemical PNBA. The H37Rv strain showed a faint band from the 2nd day onwards from inoculation till 3rd day in the earlier Antigen detection experiment. Conclusion: Rapid identification of MTB culture isolate is a pressing need for diagnosis and proceeding to perform drug susceptibility testing. MPT64 TB Ag detection ICT kit is a rapid, reliable method, good substitute for molecular identification methods, and conventional biochemical test which is time-consuming and technically demanding. The early detection of Antigen can be used as an effective tool in diagnosis.
Anti-inflammatory activity of theophylline on carrageenan-induced paw edema in male wistar rats
K Srinivasa,BVS Chandrasekhar,J Srinivasa
International Journal of Basic & Clinical Pharmacology , 2013, DOI: 10.5455/2319-2003.ijbcp20130612
Abstract: Background: Evaluate the anti-inflammatory property of theophylline on rat hind paw edema using carrageenan-induced acute inflammatory model. Methods: Wistar male rats (150-200 gm) were divided into 7 groups- 3 standard groups, 3 test groups and 1 control group. Each group consists of six rats. A control group was treated with 0.2ml of normal saline, 3 standard groups were treated with different doses of Diclofenac (Standard drug): 5 mg/kg, 10 mg/kg, 15 mg/kg body weight, respectively and 3 test groups were treated with different doses of Theophylline (Test drug): 5 mg/kg , 10 mg/kg and 15 mg/kg, respectively. The anti-inflammatory property was assessed by plethysmograph. Results: Theophylline demonstrated a significant anti-inflammatory property at different dose levels when compared to controls (p > 0.05). However this anti-inflammatory activity was less as compared to standard drug. Conclusions: Theophylline exhibited a dose dependent anti-inflammatory activity in a carrageenan model of inflammation. [Int J Basic Clin Pharmacol 2013; 2(3.000): 298-301]
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