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Search Results: 1 - 10 of 130471 matches for " Srikumar V "
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Biochemical evaluation of low dose methyl 2-benzimidazole carbamate fungicide on male albino rats
V. Muthuviveganandavel,P. Muthuraman,S. Muthu,K. Srikumar
International Journal of Drug Delivery , 2011,
Abstract: Methyl 2-benzimidazole carbamate (carbendazim) is one of the synthetic fungicides that controlled organisms that caused plant diseases of different types. It is widely used as a preservative in leather, paint, textile, fruits and papermaking industry. It is also used as an anticancer drug in chemical medicine. In the present study low concentrations of carbendazim was administered at 5, 10, 25 and 50mM doses intradermally to male albino rats. At the end of 6 hr, 12hr and 24hr duration, blood samples were collected from the animal for the analysis of biochemical and haematological parameters. Carbendazim caused an increase of cholesterol, uric acid, glucose and creatinine while serum phosphorous content was decreased. However, mean hemoglobin, WBC, E, and platelet counts increased and total RBC, N and L counts decreased. These results indicated that low dose level carbendazim contributed to toxicological effects in the rat tissues. Keywords: Methyl 2-benzimidazole carbamate; Fungicide; Rat tissues
A Study on Knowledge, Attitude and Practice Regarding Voluntary Blood Donation among Medical Students in Puducherry, India
V. Kowsalya,R. Vijayakumar,R. Chidambaram,R. Srikumar
Pakistan Journal of Biological Sciences , 2013,
Abstract: Knowledge, attitude and practice studies have been used to understand the various factors that influence blood donation which is the basis for donor mobilization and retention strategies. Role of youngsters in voluntary blood donation is crucial to meet the demand of safe blood. The present study was aimed to assess the level of knowledge, attitude and practice regarding voluntary blood donation among the health care students. A validated and pre-tested questionnaire on knowledge, attitude and practice on blood donation were assessed among 371 medical students from Sri Lakshmi Narayana Institute of Medical Sciences and Research Institute, Puducherry, India. Result showed that knowledge on blood donation among respondents was 44.8% (1st year 36.7%, 2nd year 42.8% and 3rd year 54.9%). About 62.6% of non-donors (1st year 51%, 2nd year 61% and 3rd year 77%) showed positive attitude by expressing their willingness to donate blood while 22.8%.of the non-donors had negative attitude (1st year 33%, 2nd year 23% and 3rd year 13%). In practice 13.2% of students had donated blood (1st year 10%, 2nd year 13% and 3rd year 24%), in which 2.7% of male students alone donating blood on regular basis. Over all 3rd year student showed significantly higher knowledge compared with 1st years, in attitude and practice section 3rd year student’s showed significantly higher positive attitude and practice than that of 1st and 2nd years. The present study reveals that there is a positive association among knowledge, attitude and practice on blood donation, which suggest that positive attitude and practice can be improved by inculcating knowledge on blood donation among college students to recruit and donate blood regularly, which will help to achieve 100% of blood donation on voluntary basis.
Srikumar G,Hameedultah A,Arunadevi R,Somasundaram V
Indian Journal of Dermatology , 2000,
Abstract: Ochronosis is a rare disorder, which presents with distinct clinical and biochemical features. A fifty seven year old male presented with fracture femur, osteoarthritis, Oslera€ s sign, alkaptonuria and cutaneous ochronosis. Though the clinical progression of his alkaptonuria was typical, he presented interesting features including non-uniting fracture and arthritis of big and small joints.
Structured Rehabilitation Exercise Program in Parkinson’s Disease
Srikumar V,Wadhwa Sanjay,Singh U,Yadav SL
Indian Journal of Physical Medicine and Rehabilitation , 2010,
Abstract: Title of the article: A Study of structured rehabilitationexercise program in Parkinson’s diseaseContext: There is a growing need to address rehabilitationissues to supplement medical therapy.Aims: To assess the impact of rehabilitation interventionin the functional status and quality of life in patients withParkinson’s disease.Settings and Design: Prospective follow-up study in ateaching hospitalMaterials and Methods: Twenty-eight cases withParkinson’s Disease on a stable pharmacological regimenand moderately disabled participated in this study. Allpatients were given the same set of exercises. Duringthe first month, patients performed exercises undersupervision at the hospital and rest of the days at home.In the second and third month, patients continued thesame exercises at home. During the fourth month, patientsmaintained their usual level of physical activity butdiscontinued the exercises. All patients were evaluatedat 0, 1, 2, 3 and 4 months. Outcome measures used wereUnified Parkinson’s Disease Rating Scale (UPDRS)version 3.0, Webster step seconds product, andParkinson’s Disease Quality of Life Questionnaire(PDQL)Results: Significant improvements were observed inUPDRS section 1 (Mentation, behavior and mood),sections 2 and 6 (Activities of Daily Living), PDQLsubscales (parkinsonian symptoms, systemic symptomsand social functioning), and Webster step-seconds product.Conclusions: Systematic program of physical therapy isbeneficial in patients suffering from moderately disabledParkinson’s disease. Activities of daily living like dressing,turning in bed and walking respond favorably to exercises.Quality of life improves considerably following exercisesleading to increased social participation
Contractures and Drug Abuse
Srikumar V,Wadhwa S,Singh U,Yadav SL
Indian Journal of Physical Medicine and Rehabilitation , 2009,
Abstract: Contracture is limitation of complete range of motion,active or passive, due to joint, muscle or soft-tissuelimitations. Myogenic contractures can be due to trauma,inflammation, degenerative changes, ischemia, andspasticity. A 32-year-old patient presented with complaintsof inability to sit on the floor and limitation of multiplejoint movements which progressed over the past threeyears. He had a history of multiple drug injections(pentazocine) for the past six years at multiple sitesthroughout the body. He was started on narcoticanalgesics for chronic abdominal pain followingpancreatitis. Deltoid, quadriceps, hamstring and calfmuscles were indurated and contracted. Bilateral wingingof scapula was present. Contractures are commonlyassociated with joint diseases; but normal radiographsand indurated muscles support a myogenic pathology inthis case. Myogenic contracture due to parenteral narcoticabuse is a rare entity.
Implementation of PBL curriculum involving multiple disciplines in undergraduate medical education programme
Srikumar Chakravarthi,Nagaraja Haleagrahara
International Education Studies , 2010, DOI: 10.5539/ies.v3n1p165
Abstract: This article describes how a multidisciplinary problem-based learning (PBL) curriculum was established at the International Medical University in Malaysia for preclinical education in a 5-semester phase 1 programme. Based on positive feedback from a modified PBL program implemented in one discipline, a multidisciplinary PBL curriculum was established. PBL training for facilitators and students, development of resource materials, curriculum design, and case writing were done in a manner that is consistent with the characteristics and learning style preferences of undergraduate medical students. About 80 percent of the lectures were kept in the new PBL program. The multidisciplinary PBL curriculum has been successful in helping undergraduate medical students mentally construct an understanding of the interrelationship between medical knowledge and basic science concepts. The experience ai IMU indicates that there are clear benefits for students in the PBL format. A benefit to faculty is that PBL tutorial facilitators were partly liberated from their traditional roles and developed additional skills for facilitating. However, conflict arises when PBL-trained students encounter the traditional exam-centered education system.
A Plant Oxysterol as a regulator of glucose homeostasis
P. Muthuraman,K. Srikumar
International Journal of Phytomedicine , 2011,
Abstract: Plant oxysterols like 28-homobrassinolide (HB) exhibit partial structural homology to oxycholesterols. HB’s effect in cell metabolism was therefore investigated using rat model. Oral administration of HB to streptozotocin induced diabetic male albino wistar rats, reduced circulating glucose level to normal level. Serum insulin content was increased by HB treatment. HB elevated the hexokinase (HK) enzyme activity of liver in the experimental animal. Peroxidative damage of cellular lipids was reduced by HB based on quantitative estimates of malonyldialdehyde (MDA) and 4-hydroxy nonenol (4-HNE) content of erythrocyte samples. The antihyperglycemic and antioxidant potential of HB was presented. Keywords: Insulin; glucose; hexokinase; protein; receptor
International Journal of Pharmaceutical Research and Development , 2010,
Abstract: Human infections, particularly those involving the skin and mucosal surface constitute a serious problem, especially in tropical and subtropical countries. There has been a worldwide move towards the use of traditional medicines due to concerns over the more invasive, expensive and potentially toxic mainstream practices. In the present study aqueous and ethanolic extracts of Triphala and its individual components (T. chebula, T. belerica and E. officinalis) were tested against the fungus Trichophyton rubrum, Microsporum canis and Aspergillus fumigates. Result showed ethanolic extract had high inhibitory action against the studied fungus when compared to aquesous extract. In both aqueous and ethanolic extract T. chebula showed high inhibitory activity followed by T. belerica, Triphala formulation and E. officinalis. The present study revealed that both individual and combined aqueous and ethanolic extracts of Triphala shown anti-fungal activity and this study also revealed ethanolic extract is an ideal solvent.
Analysis of the psychological impact of Problem Based Learning (PBL) towards self directed learning among students in undergraduate medical education
Srikumar Chakravarthi,Priya Vijayan
International Journal of Psychological Studies , 2010, DOI: 10.5539/ijps.v2n1p38
Abstract: The psychological impact of a learning tool towards self directed learning is an important outcome of medical education. Although problem based learning is believed to facilitate self directed learning, previous studies have reported conflicting results. This longitudinal survey explored the perceived psychological changes in self directed learning for two and a half years in an undergraduate phase 1 medical education program with an integrated problem-based learning curriculum. 170 of 200 students (response rate, 85%) completed the Self-Directed Learning Readiness Scale at five different time points: at the beginning of each semester year and at program completion. Scores were significantly lower during the first semester compared with other years, and fifth semester scores were significantly higher than in previous years. Scores on the three subscales (i.e., self-management, desire for learning, and self-control) increased significantly during the five semesters years of the programme. These findings support self-directed learning as a maturational process seen psychologically by the students. Implications for medical faculty and curriculum development are discussed.
An Inventory of Preposition Relations
Vivek Srikumar,Dan Roth
Computer Science , 2013,
Abstract: We describe an inventory of semantic relations that are expressed by prepositions. We define these relations by building on the word sense disambiguation task for prepositions and propose a mapping from preposition senses to the relation labels by collapsing semantically related senses across prepositions.
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