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Search Results: 1 - 10 of 143 matches for " Srabanti Maji "
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Gene Finding Using Hidden Markov Model
Srabanti Maji,Deepak Garg
Journal of Applied Sciences , 2012,
Abstract: The objective of this study is to perform mini review on Hidden Markov Models (HMMs) which is recently important and popular among bioinformatics researchers and large no of software tools are based on this technique. The mathematical foundations of HMMs shall be considered first in brief manner and then the gene identification application. In the case of gene identification process, HMM basically resolve three basic problems: First is the evaluation problem, in this it computes the probability that a particular HMM will generates a given sequence of observations. Second is Decoding problem, in which it will uncover the most likely hidden state and Third is Learning problem, it is used to adjust the model parameter and train the HMM to find an optimal model. Evaluation problem can be solved by using Forward and Backward algorithm, Decoding problems are solved by using Viterbi algorithm and posterior decoding algorithm and then Learning problems are solved through Viterbi training algorithm and Baum-Welch algorithm. Finally, some limitations of the current approaches and future directions are also reported.
Synthesis and Spectral Studies of CdTe–Dendrimer Conjugates
Ghosh Srabanti,Saha Abhijit
Nanoscale Research Letters , 2009,
Abstract: In order to couple high cellular uptake and target specificity of dendrimer molecule with excellent optical properties of semiconductor nanoparticles, the interaction of cysteine-capped CdTe quantum dots with dendrimer was investigated through spectroscopic techniques. NH2-terminated dendrimer molecule quenched the photoluminescence of CdTe quantum dots. The binding constants and binding capacity were calculated, and the nature of binding was found to be noncovalent. Significant decrease in luminescence intensity of CdTe quantum dots owing to noncovalent binding with dendrimer limits further utilization of these nanoassemblies. Hence, an attempt is made, for the first time, to synthesize stable, highly luminescent, covalently linked CdTe–Dendrimer conjugate in aqueous medium using glutaric dialdehyde (G) linker. Conjugate has been characterized through Fourier transform infrared spectroscopy and transmission electron microscopy. In this strategy, photoluminescence quantum efficiency of CdTe quantum dots with narrow emission bandwidths remained unaffected after formation of the conjugate.
Dynamic Disorder in Quasi-Equilibrium Enzymatic Systems
Srabanti Chaudhury,Oleg A. Igoshin
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0012364
Abstract: Conformations and catalytic rates of enzymes fluctuate over a wide range of timescales. Despite these fluctuations, there exist some limiting cases in which the enzymatic catalytic rate follows the macroscopic rate equation such as the Michaelis-Menten law. In this paper we investigate the applicability of macroscopic rate laws for fluctuating enzyme systems in which catalytic transitions are slower than ligand binding-dissociation reactions. In this quasi-equilibrium limit, for an arbitrary reaction scheme we show that the catalytic rate has the same dependence on ligand concentrations as obtained from mass-action kinetics even in the presence of slow conformational fluctuations. These results indicate that the timescale of conformational dynamics – no matter how slow – will not affect the enzymatic rate in quasi-equilibrium limit. Our numerical results for two enzyme-catalyzed reaction schemes involving multiple substrates and inhibitors further support our general theory.
Ivana Maji
Poljoprivreda (Osijek) , 2010,
Indian Streams Research Journal , 2012,
Abstract: Eroticism has a wider definition. Martin Amis is the most successful postmodern British fiction writer in defining this. The Pregnant Widow is a demi-bible of polished eroticism. Every psalm of this bible beats post feministic pulse. This small excerpt will be an endeavour to conceptualize post feminism and how it is defined by Amis in his novel The Pregnant Widow. Feminism is often defined as a movement and revolution for the liberation of women. This research paper will focus how feminism came as promise and how they are left untouched. My curiosity equally runs high if this same frustration continues even in the case of post feminism also. Is Amis uniquely unparallel in sharpshooting this?
Linearized Additive Classifiers
Subhransu Maji
Computer Science , 2011,
Abstract: We revisit the additive model learning literature and adapt a penalized spline formulation due to Eilers and Marx, to train additive classifiers efficiently. We also propose two new embeddings based two classes of orthogonal basis with orthogonal derivatives, which can also be used to efficiently learn additive classifiers. This paper follows the popular theme in the current literature where kernel SVMs are learned much more efficiently using a approximate embedding and linear machine. In this paper we show that spline basis are especially well suited for learning additive models because of their sparsity structure and the ease of computing the embedding which enables one to train these models in an online manner, without incurring the memory overhead of precomputing the storing the embeddings. We show interesting connections between B-Spline basis and histogram intersection kernel and show that for a particular choice of regularization and degree of the B-Splines, our proposed learning algorithm closely approximates the histogram intersection kernel SVM. This enables one to learn additive models with almost no memory overhead compared to fast a linear solver, such as LIBLINEAR, while being only 5-6X slower on average. On two large scale image classification datasets, MNIST and Daimler Chrysler pedestrians, the proposed additive classifiers are as accurate as the kernel SVM, while being two orders of magnitude faster to train.
Hydrodynamic Flow between Two Non-Coincident Rotating Disks Embedded in Porous Media  [PDF]
Rabindranath Jana, Mrinal Maji, Sanatan Das, Sovan Lal Maji, Swapan Kumar Ghosh
World Journal of Mechanics (WJM) , 2011, DOI: 10.4236/wjm.2011.12007
Abstract: Hydrodynamic viscous incompressible fluid flow through a porous medium between two disks rotating with same angular velocity about two non-coincident axes has been studied. An exact solution of the govern-ing equations has been obtained in a closed form. It is found that the primary velocity decreases and the sec-ondary velocity increases with increase in porosity parameter to the left of the z-axis and the result is re-versed to the right of the z-axis. It is also found that the torque on the disks increases with increase in either rotation parameter or porosity parameter. For large rotation, there exist a thin boundary layer near the disks and the thickness of this boundary layer decreases with increase in porosity parameter.
Mathematical Modeling and Simulation of CNG-Diesel Dual Fuel Engine Cycle Processes
Ranbir Singh,Sagar Maji
Journal of Engineering and Applied Sciences , 2012, DOI: 10.3923/jeasci.2012.175.183
Abstract: This study presents a detailed mathematical modeling and simulation study of CNG-diesel dual fuel compression ignition engine cycle processes using EES (Engineering Equation Solver) software. By means of a step-by-step simulation approach, the values of pressure, volume and temperature at all the state points in the ideal, air-diesel and CNG-diesel dual fuel cycles are computed. Various performance parameters such as thermal efficiency, power output, mean effective pressure and network output are evaluated for chemically correct (Y = Ycc ) air fuel mixtures assuming adiabatic combustion and full load operation for diesel and CC CNG-diesel fuel modes. CNG available in National Capital Territory of Delhi has chemical composition with methane content of 84.5% on Mole basis. In this study, the impact of other two main constituents of CNG, i.e., Ethane (C2H6 ) and Propane (C3H8 ) on the CNG-diesel dual fuel engine parameters is also analyzed. The predicted 2 6 3 8 results of various performance parameters of dual fuel cycle using 15% diesel fuel and 85% CNG fuel with 100% methane (CH4) in it and with 84.5% methane, 12.5% ethane and 3% propane are computed and presented 4 graphically. Predicted results of cycle simulation indicate that conversion of diesel to CNG-diesel is possible with no change in compression ratio, engine design and engine basic structure.
Dual Fueling of a Twin-Cylinder Compression Ignition Engine with Diesel and CNG
Ranbir Singh,Sagar Maji
Journal of Engineering and Applied Sciences , 2012, DOI: 10.3923/jeasci.2012.90.99
Abstract: This study presents a detailed experimental research carried out on a twin-cylinder, four-stroke direct injection compression ignition engine converted to operate on dual fuel mode using Compressed Natural Gas (CNG) as the primary fuel. A venturi mixer is designed by developing a computer program in EES (Engineering equation solver) Software and then fabricated for mixing proper amount of CNG with air before admission to engine cylinder. Data for analysis of performance parameters such as brake thermal efficiency and brake specific fuel consumption was recorded both for straight diesel and dual fuel modes of operations. Engine running cost analysis was carried out on the basis of fuel consumption cost for 1 h of continuous operation of diesel engine at a particular load for both the modes. Experimental results indicate that with an increase in CNG substitution rate, brake thermal efficiency of CNG-diesel dual fuel engine is low at low loads but it is remarkably high at higher engine loads. Brake specific fuel consumption for dual fuel mode is better than pure diesel mode as the rate of CNG substitution was increased. The cost of fuel for running a CNG-diesel dual fuel engine is found less than that for pure diesel engine as the CNG substitution rate increases. In this study, 90% saving in consumption of conventional diesel fuel is achieved by its replacement with cheap and abundantly available CNG fuel.
Golden Research Thoughts , 2012, DOI: 10.9780/22315063
Abstract: Endless experimentation which is education. This present paper will be an endeavour to map Tagore's idea of ideal educational method and his dream of Prakitir Patshala. This essay will also focus on the issue of desired educational institution, where the giver of the lesson and their pupils will drink pleasure equally for learning the new, knowing the unknown. In that case, both will keep open the thresholds of their hearts. May digitalization and globalization strangle the breath of the century; Tagore will function equally as balm in curing the maladies of the century.
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