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Search Results: 1 - 10 of 32575 matches for " Sne?ana Rau? Balind "
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Extremely Low Frequency Magnetic Field (50 Hz, 0.5 mT) Reduces Oxidative Stress in the Brain of Gerbils Submitted to Global Cerebral Ischemia
Sneana RauBalind, Vesna Selakovi?, Lidija Radenovi?, Zlatko Proli?, Branka Jana?
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088921
Abstract: Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both carotid arteries, 3-month-old gerbils were continuously exposed to ELF-MF for 7 days. Nitric oxide and superoxide anion production, superoxide dismutase activity and index of lipid peroxidation were examined in the forebrain cortex, striatum and hippocampus on the 7th (immediate effect of ELF-MF) and 14th day after reperfusion (delayed effect of ELF-MF). Ischemia per se increased oxidative stress in the brain on the 7th and 14th day after reperfusion. ELF-MF also increased oxidative stress, but to a greater extent than ischemia, only immediately after cessation of exposure. Ischemic gerbils exposed to ELF-MF had increased oxidative stress parameters on the 7th day after reperfusion, but to a lesser extent than ischemic or ELF-MF-exposed animals. On the 14th day after reperfusion, oxidative stress parameters in the brain of these gerbils were mostly at the control levels. Applied ELF-MF decreases oxidative stress induced by global cerebral ischemia and thereby reduces possible negative consequences which free radical species could have in the brain. The results presented here indicate a beneficial effect of ELF-MF (50 Hz, 0.5 mT) in the model of global cerebral ischemia.
Viability of old house borer (Hylotrupes bajulus) larvae exposed to a constant magnetic field of 98 mT under laboratory conditions
RauSneana,Todorovi? Dajana,Proli? Z.
Archives of Biological Sciences , 2009, DOI: 10.2298/abs0901129r
Abstract: The purpose of our experiment was to establish how exposure to a constant magnetic field of 98 mT affects behavior in terms of viability and larval mass of the old house borer (Hylotrupes bajulus L.). It is demonstrated that larvae exposed to this magnetic field show statistically significant higher viability, as well as a tendency of mass increase in comparison with the control group. These results can be attributed to the modulatory effect of the employed external magnetic field on metabolism and neurohumoral regulation in the insects.
Investment Activity in Small Open Economies  [PDF]
Vera Karadjova, Sneana Di?evska
Technology and Investment (TI) , 2014, DOI: 10.4236/ti.2014.52008
Abstract:


The paper gives a brief elaboration of the basic macroeconomic aspects of investments with emphasis on the specificities of small open economies in the process, theoretically elaborates the need for openness of small economies (especially the economies that need the acceleration of their development), then highlights the risks and opportunities arising from the investment activity both on the micro and macro level. Further distinguishes between investments in financial instruments and in real investment projects, emphasize the need for creation of an optimal diversified portfolio. Finally, the paper underlines the need for various forms of foreign direct investment for all economies, particularly the opportunities and threats arising in small open economies, to complete the wholeness with empirical data of the previously elaborated matters on the example of the Republic of Macedonia as a small open economy.


MARP Protein Family: A Possible Role in Molecular Mechanisms of Tumorigenesis
Sne ana Koji
Journal of Medical Biochemistry , 2010, DOI: 10.2478/v10011-010-0024-9
Abstract: The MARP (muscle ankyrin repeat protein) family comprises three structurally similar proteins: CARP/Ankrd1, Ankrd2/Arpp and DARP/Ankrd23. They share four conserved copies of 33-residue ankyrin repeats and contain a nuclear localization signal, allowing the sorting of MARPs to the nucleus. They are found both in the nucleus and in the cytoplasm of skeletal and cardiac muscle cells, suggesting that MARPs shuttle within the cell enabling them to play a role in signal transduction in striated muscle. Expression of MARPs is altered under different pathological conditions. In skeletal muscle, CARP/Ankrd1 and Ankrd2/Arpp are up-regulated in muscle in patients suffering from Duchene muscular dystrophy, congenital myopathy and spinal muscular atrophy. Mutations in Ankrd1 gene (coding CARP/Ankrd1) were identified in dilated and hypertrophic cardiomyopathies. Altered expression of MARPs is also observed in rhabdomyosarcoma, renal oncocytoma and ovarian cancer. In order to functionally characterize MARP family members CARP/Ankrd1 and Ankrd2/Arpp, we have found that both proteins interact with the tumor suppressor p53 both in vivo and in vitro and that p53 up-regulates their expression. Our results implicate the potential role of MARPs in molecular mechanisms relevant to tumor response and progression.
Biohemijski Aspekti, Laboratorijska Dijagnoza I Pra enje Povi ene Koncentracije Holesterola: Preporuke NCEP ATP III
Sne ana Jovi i
Journal of Medical Biochemistry , 2008, DOI: 10.2478/v10011-007-0044-2
Abstract: The Third Report of the expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III, ATP III) constitutes the National Cholesterol Education Program's (NCEP's) updated clinical guidelines for cholesterol testing and clinical management of patients with high blood cholesterol. While ATP III maintains attention to intensive treatment of patients with coronary heart disease (CHD), its major new feature is a focus on primary prevention in persons with multiple risk factors. ATP III continues to identify elevated LDL cholesterol as the primary target of cholesterol lowering therapy. A basic principle of prevention is that the intensity of risk reduction therapy should be adjusted to a person's absolute risk. Risk assessment requires measurement of LDL cholesterol as part of lipoprotein analysis and identification of accompanying risk determinants (presence or absence of CHD, other clinical forms of atherosclerotic disease, diabetes, cigarette smoking, hypertension, low HDL cholesterol, family history of premature CHD, age). The category of highest risk consists of CHD and CHD risk equivalents - persons with absolute 10-year risk for major coronary events (death and myocardial infarction) >20%. The second category consists of persons with multiple (2+) risk factors in whom 10-year risk for CHD is ≥20%. Absolute risk is estimated from Framingham risk scores. The third category consists of persons having 0-1 risk factor. The LDL cholesterol goal for each category is defined and it can be achieved with dietary changes and/or drug therapy. European guidelines on cardiovascular disease (CVD) prevention in clinical practice recommend using the SCORE (Systematic COronary Risk Evaluation) Risk Charts in order to assess the risk for development of CVD, which is defined in terms of the absolute 10 year probability of developing a fatal cardiovascular event. The aim of this paper is to introduce parts of the NCEP's ATP III and European guidelines important for their implementation in laboratory practice.
Conservation biogeography: The modern scientific contribution of biogeography to the improvement of nature conservation
?ur?i? Sneana
Glasnik Srpskog Geografskog Dru?tva , 2009, DOI: 10.2298/gsgd0904311d
Abstract: In present times, there is a clear and growing need for applying theoretical biogeographic achievements in improving the state of biodiversity and conservation. Conceptual principles of conservation biogeography take the research into the relationship between fundamental biogeographic principles and the need for their appliance in nature conservation as the basic theory model, based upon biogeographic studies of isolated ranges. This paper is meant to point out the differences between spatial and functional isolation and the effects these have on the stability of populations and species. In light of this need to apply theories in biodiversity and nature conservation, it is important to research not only the processes that depend solely upon natural factors, but also those that are caused by a number of human-induced changes, e.g. habitat fragmentation, climate change or biotic homogenization.
Forests as the factor of the economy development of the Ra ka region
Vujadinovi? Sneana M.
Glasnik Srpskog Geografskog Dru?tva , 2003, DOI: 10.2298/gsgd0302061v
Abstract: Forests represent the significant natural resource of the Ra ka region. The preservation of forests ecosystems, and space potential offer, a favourable basis for their many-functional usage. For the time being, the productive, i.e., economic function, is dominant. The forests on the territory of the Prijepolje Forest Organization present the main raw material basis. In the whole cut wood volume of Serbia (state forests), the above mentioned organization participates with 37,1%. Opposite to that fact, the economic effects that the region economy has from the forest utilization, are far less than the potentials. Forest resources are neither enough nor adequately used. That greatly complicates the development of wood industry, as well as the other activities whose prosperity is connected with forests. Making and realization of plans for protection, fending forests and utilization, constructing infrastructure, tending and preservation of wild life, rational exploitation of forest resources, are the trends of the future usage of the Ra ka region forest natural wealth.
Structure and aims of land utilization the municipality of Knic
Vujadinovi? Sneana
Glasnik Srpskog Geografskog Dru?tva , 2008, DOI: 10.2298/gsgd0802079v
Abstract: Among developmental potentials of the municipality of Knic land is of primary significance. A survey of types and fertility land classes was presented in the paper. The structure of surfaces was analyzed according the way of utilization as well as changes that occurred due to construction of the river Gruza accumulation. Spatial differentiation of structural aims for the utilization of the whole land and agricultural one was carried out, which confirmed the physical-geographic and socio-economic heterogeneity of the area. It was pointed to numerous limiting factors of optimal exploitation of land fund (with a special review on shortening the properties). Appropriate measures and activities were also suggested.
Biogeographic foundations of creating protected areas networks
?ur?i? Sneana
Glasnik Srpskog Geografskog Dru?tva , 2010, DOI: 10.2298/gsgd1004147d
Abstract: In this study, biogeographic adequacy and potentials of application systems for nature conservation through creating networks of protected areas will be analyzed. This approach in overcoming the consequences of the more intense process of fragmentation and deficiency of habitats has distinguished appliance in the practice of nature conservation in spatial proportions, which include multiple heterogeneous biotic and ecological conditions even of the entire continents.
Ecological and biogeographical consequences of the fragmentation process
?ur?i? Sneana
Glasnik Srpskog Geografskog Dru?tva , 2012, DOI: 10.2298/gsgd1201161d
Abstract: This paper will analyze the cause of, and ecological and biogeographical consequences of fragmentation process of habitats and ecosystems. Fragmentation process of the autochthonous habitats that without doubt leads also towards the break in their continuity shows by placement in all areas that are under the anthropogenic influence, and as well under the influence of the natural hazards. Spatial and functional isolation as the consequences of fragmentation can be overcome with the help of the formation of the ecological networks and corridors whose dynamic of management will be in accordance with the dynamic of change in habitats formed as the consequence of the fragmentation. [Projekat Ministarstva nauke Republike Srbije, br. 176008]
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