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Search Results: 1 - 10 of 1010 matches for " Siddiqui Farhan "
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Cutaneous metastasis in renal cell carcinoma
Ahmad Shamshad,Zafar Uzma,Siddiqui Farhan,Akhtar Kafil
Journal of Cytology , 2008,
Abstract: A case of renal cell carcinoma (RCC) occurring in a 65 year-old male presenting primarily as cutaneous metastasis to the chest, is being reported for its unusual presentation in the form of a skin nodule, even before the development of any urological presentation. RCC had metastasised to the liver as well. This case emphasises the importance of looking for a primary renal cancer in cutaneous metastasis cases as most of these patients have recurrent or multifocal metastatic disease.
Eumycetoma versus actinomycetoma: Diagnosis on cytology
Afroz Nishat,Khan Nazoora,Siddiqui Farhan,Rizvi Mehar
Journal of Cytology , 2010,
Abstract: Eumycetoma is a chronic cutaneous and subcutaneous infection caused by various genera of fungi producing specific colored granules known as grains. A 45-year-old farmer presented clinically with a left foot mass with multiple discharging sinuses existing for last 3 years. Clinical and radiological findings suggested a diagnosis of chronic osteomyelitis with suspicion of tuberculosis. Imprints plus fine needle aspiration cytology (FNAC) smears exhibited distinct brown-black colonies of a fungus having branching and septate hyphae embedded in matrix like material against a mixed inflammatory background. Periodic acid Schiff (PAS) stain gave positive staining and subsequent fungal culture confirmed the cytological diagnosis and aided in species identification as Madurella mycetomatis. Thus, eumycetoma can precisely be diagnosed and confidently differentiated from similar conditions such as actinomycetoma by simple and inexpensive cytological techniques such as FNAC and imprint smears, employing routine May-Gr nwald-Giemsa, Papanicolaou and simple PAS stains on cytological specimen, thus leading to rapid diagnosis for institution of correct treatment.
Prevalence of hepatitis C virus in Aligarh: A seven year experience
Siddiqui Farhan,Akhtar Kafil,Sherwani Rana,Rehman Khaliqur
Indian Journal of Community Medicine , 2009,
Dual Wavelength RP-HPLC Method for Simultaneous Determination of Two Antispasmodic Drugs: An Application in Pharmaceutical and Human Serum
Najmul Hasan,Mathurot Chaiharn,Sauleha Khan,Hira Khalid,Nawab Sher,Farhan Ahmed Siddiqui,Muhammad Zain Siddiqui
Journal of Analytical Methods in Chemistry , 2013, DOI: 10.1155/2013/297285
Abstract: A reverse phase stability indicating HPLC method for simultaneous determination of two antispasmodic drugs in pharmaceutical parenteral dosage forms (injectable) and in serum has been developed and validated. Mobile phase ingredients consist of Acetonitrile?:?buffer?:?sulfuric acid 0.1?M (50?:?50?:?0.3 v/v/v), at flow rate 1.0?mL/min using a Hibar μBondapak ODS C18 column monitored at dual wavelength of 266?nm and 205?nm for phloroglucinol and trimethylphloroglucinol, respectively. The drugs were subjected to stress conditions of hydrolysis (oxidation, base, acid, and thermal degradation). Oxidation degraded the molecule drastically while there was not so much significant effect of other stress conditions. The calibration curve was linear with a correlation coefficient of 0.9999 and 0.9992 for PG and TMP, respectively. The drug recoveries fall in the range of 98.56% and 101.24% with 10?pg/mL and 33?pg/mL limit of detection and limit of quantification for both phloroglucinol and trimethylphloroglucinol. The method was validated in accordance with ICH guidelines and was applied successfully to quantify the amount of trimethylphloroglucinol and phloroglucinol in bulk, injectable form and physiological fluid. Forced degradation studies proved the stability indicating abilities of the method. 1. Introduction Chemically, phloroglucinol (1,3,5-trihydroxybenzene, PG) and its methylated derivative tri-O-methylphloroglucinol (TMP), Figure 1, are established pharmaceutical agents inhibit the action of catechol-O-methyl transferase, inducing relaxation of smooth muscles, and decreasing glycerol-induced abdominal pain and are also characterized by a swift and strong spasmolytic activity, hence relieving pain. Therefore, PG is often used in combination with trimethylphloroglucinol as an antispasmodic drug and is regarded to be effective in decreasing smooth muscle spasm. PG/TMP combination is recommended against biliary calculi, severe pain of urinary or gastrointestinal tract, pain of abdominal region, spastic conditions of the female genital system, and pain in gynecology [1–7]. Figure 1: Chemical structures of phloroglucinol and trimethylphloroglucinol. Literature survey reveals that some of the analytical methods for phloroglucinol are available including extraction and high-performance liquid chromatography (HPLC) [8–10], HPLC-mass spectrometry [11, 12], gas chromatography-mass spectrometry [13], and spectrophotometry [14]. Other reported methods include titrimetry, spectrophotometry, paper chromatography, and flow injection analysis [15–20]. However, there is
Morphometric Assessment of Wadi Wala Watershed, Southern Jordan Using ASTER (DEM) and GIS  [PDF]
Yahya Farhan
Journal of Geographic Information System (JGIS) , 2017, DOI: 10.4236/jgis.2017.92011
Abstract: Morphometric analysis is of vital concern to understand hydromophological processes in a given watershed, and thus, it is a priority for assessing water resources in drainage basins. A morphometric analysis was conducted to identify the drainage properties of Wadi Wala and the 23 fourth-order sub-basins. ASTER DEM data was employed to compile slope, elevation, and aspect maps. Arc GIS software was used to measure and calculate basic, derived and shape morphometric parameters. W. Wala is found to be a sixth-order drainage basin, and the drainage pattern is trellis to sub-trellis in the central and lower part of the catchment, whereas it is dendritic to sub-dendritic pattern in the southern and northern parts. The slopes of the catchment vary from 0° - 5° to >35° in slope categories. Tectonic uplifting and tilting, lithology, structure and rejuvenation are the major factors controlling morphological variation over the watershed. The recognized fault systems are chiefly controlling the drainage pattern, and the elongated shape of the sub-basins is attributed to dense lineaments in the central and eastern parts of the watershed. The Rb values for the entire catchment and the sub-catchments range from 2 to 7, with a mean of 4.55, which indicates the distortion of drainage pattern by geological structure. Hypsometric integral values are high for the W. Wala watershed and the sub-basins, where it ranges from 70% to 89%. High HI values indicate that drainage basins are at the youth-age stage of geomorphic development, and they are affected by tectonic uplifting, tilting, and the dominance of hillslope process. Variation in HI values is apparent between sub-basins located at the western part, or, the rejuvenated belt where HI values range from 85% to 89%. Whereas the HI values of the sub-basins located at the eastern part of the watershed, vary from 70% to 84%. Regression analysis reveals that R2 values, which represent the degree of control of driving parameters on HI are reasonably high for the height of local base level (m) and the mean height of sub-basins (m). Both parameters contribute 0.42 and 0.39 respectively (where the F-value is significant at 0.1% and 0.5% levels). Such results imply that the height of local base level (m), and the mean height (m) are the only morphometric driving parameters which have significant control on HI values in the W. Wala watershed. High annual soil loss and sediment load estimated recently, denote that the catchment is highly susceptible to surface erosion at present. Hence, the present study, and
Prevalence of Hepatitis ‘B’ and Hepatitis ‘C’ among preoperative cataract patients in Karachi
Syed Naeem, Efaza Siddiqui, Abdul Kazi, SumaiyaTauseeq Khan, Farhan E Abdullah, Idrees Adhi
BMC Research Notes , 2012, DOI: 10.1186/1756-0500-5-492
Abstract: A descriptive study was conducted among 377 patients presenting for cataract surgery to Department of Ophthalmology Unit I, CHK from April 2010 to May 2011. Convenience sampling was done to recruit the participants aged 18?years and above. The patients were screened for Hepatitis B and C infections and findings were recorded on a structured compilation sheet.The total prevalence of both Hepatitis B and Hepatitis C in preoperative Cataract patients was found to be 49 out of 377(12.99%). Overall, 8 out of 377 (2.1%) patients were HBsAg positive and 42 out of 377 (11.1%) were Anti-HCV positive. Only 1 patient was found with a co-infection with both HBsAg and Anti-HCV positive.High proportions of Hepatitis B and C are reported among preoperative cataract patients of Karachi. Routine serological screening prior to surgery should be made mandatory so that asymptomatic patients would no longer pose a threat to its spread.Hepatitis is described as an infection with swelling and inflammation of the liver that if progresses, may lead to cirrhosis or cancer [1]. Sometimes people contract hepatitis with limited or no symptoms but often it leads to jaundice, anorexia (poor appetite) and diarrhea. Hepatitis is caused by a wide variety of causatives like alcohol, poison and autoimmunity but most cases of hepatitis are reported by viruses [1].Hepatitis B (HBV) and Hepatitis C (HCV) are one of the viral types of Hepatitis that lead to irritation, inflammation and swelling of the liver capable of causing acute and chronic form of hepatitis [2]. Worldwide 2 billion people have been infected with HBV and 350 million (5-15% of the total cases) are carriers of the virus [3]. According to WHO estimates, HCV prevalence is 3% of world population with 170 million cases. Almost 50% of all cases become chronic carriers at risk of liver cirrhosis and liver cancer [4].HBV can be contracted through the blood, semen, vaginal fluids, and other body fluids of an infected individual having hepatitis
Journal of the Chilean Chemical Society , 2010, DOI: 10.4067/S0717-97072010000200002
Abstract: 1. a simple isocratic reversed phase high performance liquid chromatographic (hplc) method using c18 column with ultraviolet detection at 225 nm has been described for quantitative determination of gliquidone in formulation and human serum. the system is operated at room temperature using a mobile phase consisting of methanol: water (90:10) adjusted to ph 3.50 with phosphoric acid with a flow rate of 1 in lmin-1. methylparaben is successfully used as an internal standard. the assay is reproducible, linear (concentration range of 0.60-25 μml-1) with correlation coefficient of 0.9999 and accurate (99.23 to 102.78%). the intra and inter run precision results are 1.14 and 1.32%. the lod and loq values are 0.03 and 0.6 μml-1, respectively there are no interfering peaks duetothe excipients present in the pharmaceutical tablet. thus, the proposed method is simple and suitable for the analysis of active ingredient in tablet dosage form and human serum.
Journal of the Chilean Chemical Society , 2010,
Abstract: 1. A simple isocratic reversed phase high performance liquid chromatographic (HPLC) method using C18 column with ultraviolet detection at 225 nm has been described for quantitative determination of gliquidone in formulation and human serum. The system is operated at room temperature using a mobile phase consisting of methanol: water (90:10) adjusted to pH 3.50 with phosphoric acid with a flow rate of 1 in Lmin-1. Methylparaben is successfully used as an internal standard. The assay is reproducible, linear (concentration range of 0.60-25 μmL-1) with correlation coefficient of 0.9999 and accurate (99.23 to 102.78%). The intra and inter run precision results are 1.14 and 1.32%. The LOD and LOQ values are 0.03 and 0.6 μmL-1, respectively There are no interfering peaks duetothe excipients present in the pharmaceutical tablet. Thus, the proposed method is simple and suitable for the analysis of active ingredient in tablet dosage form and human serum.
A Unique Case of Malignant Pleuropericardial Effusion: HHV-8-Unrelated PEL-Like Lymphoma—A Case Report and Review of the Literature
Farhan Mohammad,Muhammad Neaman Siddique,Faraz Siddiqui,M. Popalzai,Masoud Asgari,Marcel Odaimi
Case Reports in Oncological Medicine , 2014, DOI: 10.1155/2014/436821
Abstract: Primary effusion lymphoma (PEL) or body cavity lymphoma is a rare type of extra nodal lymphoma of B-cell origin that presents as lymphomatous effusion(s) without any nodal enlargement or tumor masses. It belongs to the group of AIDS related non-Hodgkin’s lymphomas. First described in 1996 in HIV infected individuals who were coinfected with Kaposi’s sarcoma-associated herpesvirus (KSHV) or HHV-8 virus, it was included as a separate entity in WHO classification of tumors of hematopoietic and lymphoid tissue in the year 2001. The definition included association with HHV-8 virus as a mandatory diagnostic criterion. However, cases were later reported where PEL-like disease process was diagnosed in HHV-8 negative patients. This was eventually recognized as a rare but distinct entity termed as “HHV-8-unrelated PEL-like lymphoma”. Herein, we are reporting a case of an elderly patient who presented with a large pleuropericardial effusion and was eventually diagnosed with this entity. Till date, only around 50 cases of HHV-8-unrelated PEL-like lymphoma have been reported and our case being EBV, HIV, and Hepatitis C negative makes it very unique and rare occurrence. We are also presenting a review of relevant literature focused mainly on comparing outcomes in patients treated with and without chemotherapy. 1. Case Presentation A 76-year-old ex-smoker male with past medical history of hypertension and atrial fibrillation presented with exertional dyspnea and a recent weight loss of 15?lbs. He denied substance abuse. Review of systems and EKG were negative. On physical examination, breath sounds at bilateral lung bases were decreased. The superficial lymph nodes, liver, and spleen were not palpable on physical examination. There was no lower extremity edema. Hemogram revealed a WBC count of 10,700?cells/mm3 with 80% granulocytes, hemoglobin of 12.3?g/dL, and platelet count of 303000/microl. Cardiac enzymes were normal. Thyroid function tests were normal. Chemistry showed mild elevation of alkaline phosphatase and GGT. Lactate dehydrogenase was 158?U/L and ESR was 23?mm/hr. Chest radiography showed enlarged cardiac silhouette and small bilateral pleural effusions. Echocardiography showed a large pericardial effusion. He underwent pericardiocentesis with removal of 800?mL of hemorrhagic fluid. Symptoms improved and patient was discharged home to follow up as an outpatient. Pericardial fluid analysis revealed 12,300 leukocytes with 90% monocytes, 246,000 erythrocytes, a protein of 4.7?g/dL, and LDH of 6,000?IU/L. The fluid was cellular and cytology showed atypical
Study of Timing Synchronization in MIMO-OFDM Systems Using DVB-T
Farhan Farhan
Mathematics , 2014, DOI: 10.5121/ijit.2014.3201
Abstract: OFDM (Orthogonal Frequency Division Multiplexing)provides the promising physical layer for 4G and 3GPP LTE Systems in terms of efficient use of bandwidth and data rates. This paper highlights the implementation of OFDM in Digital Video Broadcasting-Terrestrial (DVB-T). It mainly focuses on the timing offset problem present in OFDM systems and its proposed solution using Cyclic Prefix (CP) as a modified SC (Schmidl and COX) algorithm. It also highlights the timing synchronization as well as performance comparison through bit error rate. Synchronization issues in OFDM are important and can lead to information loss if not properly addressed. Simulations were performed to implement DVB-T system and to compare different synchronization methods under certain distribution model.
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