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Search Results: 1 - 10 of 191 matches for " Sibylle Koletzko "
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Physical Activity in German Adolescents Measured by Accelerometry and Activity Diary: Introducing a Comprehensive Approach for Data Management and Preliminary Results
Rebecca Pfitzner, Lukas Gorzelniak, Joachim Heinrich, Andrea von Berg, Claudia Klümper, Carl P. Bauer, Sibylle Koletzko, Dietrich Berdel, Alexander Horsch, Holger Schulz, for the GINIplus Study Group
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0065192
Abstract: Introduction Surveillance of physical activity (PA) is increasingly based on accelerometry. However, data management guidelines are lacking. We propose an approach for combining accelerometry and diary based PA information for assessment of PA in adolescents and provide an example of this approach using data from German adolescents. Methods The 15-year-old participants comprised a subsample the GINIplus birth cohort (n = 328, 42.4% male). Data on PA was obtained from hip-worn accelerometers (ActiGraph GT3X) for seven consecutive days, combined with a prospective activity diary. Major aspects of data management were validity of wear time, handling of non-wear time and diary comments. After data cleaning, PA and percentage of adolescents meeting the recommendations for moderate-to-vigorous activity (MVPA) per day were determined. Results From the 2224 recorded days 493 days (25%) were invalid, mainly due to uncertainties relating to non-wear time (322 days). Ultimately, 269 of 328 subjects (82%) with valid data for at least three weekdays and one weekend day were included in the analysis. Mean MVPA per day was 39.1 minutes (SD ±25.0), with boys being more active than girls (41.8±21.5 minutes vs. 37.1±27.8 minutes, p<0.001). Accordingly, 24.7% of boys and 17.2% of girls (p<0.01) met the WHO recommendations for PA. School sport accounted for only 6% of weekly MVPA. In fact, most MVPA was performed during leisure time, with the majority of adolescents engaging in ball sports (25.4%) and endurance sports (19.7%). Girls also frequently reported dancing and gymnastics (23%). Conclusion For assessment of PA in adolescents, collecting both accelerometry and diary-based information is recommended. The diary is vital for the identification of invalid data and non-compliant participants. Preliminary results suggest that four out of five German adolescents do not meet WHO recommendations for PA and that school sport contributes only little to MVPA.
Children with ADHD Symptoms Have a Higher Risk for Reading, Spelling and Math Difficulties in the GINIplus and LISAplus Cohort Studies
Darina Czamara, Carla M. T. Tiesler, Gabriele Kohlb?ck, Dietrich Berdel, Barbara Hoffmann, Carl-Peter Bauer, Sibylle Koletzko, Beate Schaaf, Irina Lehmann, Olf Herbarth, Andrea von Berg, Bertram Müller-Myhsok, Gerd Schulte-K?rne, Joachim Heinrich
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0063859
Abstract: Attention-deficit/hyperactivity disorder (ADHD) and dyslexia belong to the most common neuro-behavioral childhood disorders with prevalences of around 5% in school-aged children. It is estimated that 20–60% of individuals affected with ADHD also present with learning disorders. We investigated the comorbidity between ADHD symptoms and reading/spelling and math difficulties in two on-going population-based birth cohort studies. Children with ADHD symptoms were at significantly higher risk of also showing reading/spelling difficulties or disorder (Odds Ratio (OR) = 2.80, p = 6.59×10?13) as compared to children without ADHD symptoms. For math difficulties the association was similar (OR = 2.55, p = 3.63×10?04). Our results strengthen the hypothesis that ADHD and learning disorders are comorbid and share, at least partially, the same underlying process. Up to date, it is not clear, on which exact functional processes this comorbidity is based.
A longitudinal analysis of associations between traffic-related air pollution with asthma, allergies and sensitization in the GINIplus and LISAplus birth cohorts
Elaine Fuertes,Marie Standl,Josef Cyrys,Dietrich Berdel,Andrea von Berg,Carl-Peter Bauer,Ursula Krmer,Dorothea Sugiri,Irina Lehmann,Sibylle Koletzko,Chris Carlsten,Michael Brauer,Joachim Heinrich
PeerJ , 2015, DOI: 10.7717/peerj.193
Abstract: Background. There is a need to study whether the adverse effects of traffic-related air pollution (TRAP) on childhood asthma and allergic diseases documented during early-life persist into later childhood. This longitudinal study examined whether TRAP is associated with the prevalence of asthma, allergic rhinitis and aeroallergen sensitization in two German cohorts followed from birth to 10 years.
FADS1 FADS2 Gene Cluster, PUFA Intake and Blood Lipids in Children: Results from the GINIplus and LISAplus Studies
Marie Standl, Eva Lattka, Barbara Stach, Sibylle Koletzko, Carl-Peter Bauer, Andrea von Berg, Dietrich Berdel, Ursula Kr?mer, Beate Schaaf, Stefan R?der, Olf Herbarth, Anette Buyken, Tim Drogies, Joachim Thiery, Berthold Koletzko, Joachim Heinrich, for the GINIplus Study Group ? , and LISAplus Study Group ?
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0037780
Abstract: Background Elevated cholesterol levels in children can be a risk factor for cardiovascular diseases in later life. In adults, it has been shown that blood lipid levels are strongly influenced by polymorphisms in the fatty acid desaturase (FADS) gene cluster in addition to nutritional and other exogenous and endogenous determinants. Our aim was to investigate whether lipid levels are determined by the FADS genotype already in children and whether this association interacts with dietary intake of n-3 fatty acids. Methods The analysis was based on data of 2006 children from two German prospective birth cohort studies. Total cholesterol, HDL, LDL and triglycerides were measured at 10 years of age. Six single nucleotide polymorphisms (SNPs) of the FADS gene cluster were genotyped. Dietary n-3 fatty acid intake was assessed by food frequency questionnaire. Linear regression modeling was used to assess the association between lipid levels, n-3 fatty acid intake and FADS genotype. Results Individuals carrying the homozygous minor allele had lower levels of total cholesterol [means ratio (MR) ranging from 0.96 (p = 0.0093) to 0.98 (p = 0.2949), depending on SNPs] and LDL [MR between 0.94 (p = 0.0179) and 0.97 (p = 0.2963)] compared to homozygous major allele carriers. Carriers of the heterozygous allele showed lower HDL levels [β between ?0.04 (p = 0.0074) to ?0.01 (p = 0.3318)] and higher triglyceride levels [MR ranging from 1.06 (p = 0.0065) to 1.07 (p = 0.0028)] compared to homozygous major allele carriers. A higher n-3 PUFA intake was associated with higher concentrations of total cholesterol, LDL, HDL and lower triglyceride levels, but these associations did not interact with the FADS1 FADS2 genotype. Conclusion Total cholesterol, HDL, LDL and triglyceride concentrations may be influenced by the FADS1 FADS2 genotype already in 10 year old children. Genetically determined blood lipid levels during childhood might differentially predispose individuals to the development of cardiovascular diseases later in life.
The role of the self-concept in the relationship of menstrual symptom attitudes and negative mood  [PDF]
Sibylle Peterse, Tilman Eckloff
Health (Health) , 2011, DOI: 10.4236/health.2011.36056
Abstract: Background: A relationship between symptom attitudes and negative affect has consistently been found in a range of different symptom domains. Little is known, however, about the role of different aspects of the self in this relationship. We explored the mediating role of interferences of symptom with the self-concept in the association of menstrual symptom attitudes and depressive mood. Methods: Eighty-one women completed an online survey on menstrual symptom attitudes, perceived interferences of symptoms with various self-aspects and negative mood states. We tested our hypothesis in a mediation analysis. Results: We found a complete mediation of the relationship of symptom attitudes and depressive mood by interferences of symptoms with self-aspects. However, interferences with self-aspects did not play a role in the association of anxious mood and symptom report. Conclusion: The self-concept should receive greater attention in research on symptom attitudes and psychological well-being. This would be particularly important in research on medically unexplained symptom report.
Dynamic Activity-Related Incentives for Physical Activity  [PDF]
Julia Schuler, Sibylle Brunner
Advances in Physical Education (APE) , 2012, DOI: 10.4236/ape.2012.21001
Abstract: The present studies adopted the theoretical framework of activity- and purpose-related incentives (Rheinberg, 2008) to explain the maintenance of physical activity. We hypothesized that activity-related incentives (e.g., “fun”) increase more than purpose-related incentives (e.g., “health”) between the initiation and maintenance phase of physical activity. Additionally, change in activity-related incentives was hypothesized to be a better predictor of maintenance of physical activity than change in purpose-related incentives. Two correlative field studies with rehabilitation patients (Study 1) and Nordic Walkers (Study 2) were conducted to test the hypotheses. Participants’ incentives of physical activity were measured at the beginning of exercising and two weeks (Study 1; T2) and three months (Study 2; T2) later. At T2, participants were asked for their current physical activity. Both studies showed a greater change of activity-related incentives than purpose-related incentives. Furthermore, change in activity-related incentives was more predictive of the maintenance of physical activity than change in purpose-related incentives. The results showed the important role of activity-related incentives in maintenance of physical activity. The theoretical contribution to physical activity maintenance research and practical implications for health promotion programs were discussed.
A Pilot Study on the New USDA Meal Pattern for School Breakfast in a Sample of First-Grade Students  [PDF]
Noelle Carr, Sibylle Kranz
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.39175
Abstract: Background: The United States Department of Agriculture (USDA) recently modified the school breakfast program (SBP) to improve children’s nutrition. Based on the new patterns, schools must offer larger amounts of fruits, grains, and proteins/meats to children; the amounts of fluid foods (milk and juice) remained the same. This study examined the effect of the new food pattern on student’s consumption and food cost. Methods: The amounts and cost of foods served and wasted for one week in first grade students attending two elementary schools (n = 812) were measured. One school received the current SBP pattern (control breakfast, average number of students attending breakfast n = 81), the other school’s breakfast reflected the proposed changes (test breakfast, n = 82). To test the hypothesis that the test breakfast leads to significantly increased food cost and food waste compared to the control breakfast, the weekly average amount of the served solid and fluid foods (grams and milliliters) as well as their waste were compared between the two groups using paired student’s t-test in STATA 11 (significance at p-value < 0.05). Results: Data confirmed the hypothesis in that the test breakfast was associated with significantly higher food cost (by approximately $100/week) and solid food waste but there was no change in milk and juice consumption. Conclusions: This exploratory study indicates that a significant portion of the additional foods served to first-graders to improve their nutritional status were not consumed but wasted. Further studies in larger samples and including students from all grades are needed to examine this issue fully.
Christoph Mauntel, Carl Georg von W chter (1797 - 1880) - Rechtswissenschaft im Frühkonstitutionalismus
Sibylle Hofer
Forum Historiae Iuris , 2006,
Polémiques de la seconde dissidence . Les prises de position d’un sous-champ d’auteurs de RDA émigrés en RFA lors de la querelle littéraire interallemande des années 1990.
Sibylle Goepper
Trajectoires , 2009,
Abstract: Alors que la querelle littéraire interallemande des années 1990 est habituellement présentée sous l’angle des discussions ayant opposé les journalistes ouest-allemands aux auteurs d’ex-RDA, notre étude se concentre sur les prises de position d’un groupe d’écrivains "polémistes" originaires de RDA et ayant émigré en RFA au milieu des années 1970. C’est dans cette perspective que nous analysons trois polémiques auxquelles ils ont pris part : il s’agit d’abord du débat déclenché par la parut...
The Pediatric Patient.
Fischer, Sibylle
Alasbimn Journal , 2002,
Abstract: Paediatric nuclear medicine studies have - compared to studies in adults - special requirements in preparation, acquisition and quality. Children have special needs; realizing them can help to make the little patients more cooperative which leads to a much better quality. High quality studies are essential to get all possible, clinically relevant information out of the study and to justify the radiation exposure from the nuclear medicine study.It is an ideal situation if there is a nuclear medicine department located in the children's hospital, but also in an "adult's department" a few rules can help to make the child's visit in nuclear medicine a positive experience and to reach the required high quality standard.
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