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Search Results: 1 - 10 of 992 matches for " Shyam Sundar "
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A Green and Reliable Internet of Things  [PDF]
Shyam Sundar Prasad, Chanakya Kumar
Communications and Network (CN) , 2013, DOI: 10.4236/cn.2013.51B011
Abstract: Internet of Things (IoT) is innovation in the field of Communication where a number of intelligent devices are involved sharing information and making collaborative decision. IOT is going to be a market-changing force for a wide variety of real-time monitoring applications, such as E-healthcare, homes automation system, environmental monitoring and industrial automation as it is supporting to a large number of characteristics and achieving better cost efficiency. This article explores the emerging IoT in terms of the potential Energy Efficiency Reliability (EER) issues. This paper discusses the potential EER barriers with examples and suggests remedies and techniques which are helpful in propelling the development and deployment of IoT applications.
Antimony Toxicity
Shyam Sundar,Jaya Chakravarty
International Journal of Environmental Research and Public Health , 2010, DOI: 10.3390/ijerph7124267
Abstract: Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have remarkably decreased the incidence of antimony toxicity in the workplace. As a therapeutic, antimony has been mostly used for the treatment of leishmaniasis and schistosomiasis. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections. Quality control of each batch of drugs produced and regular monitoring for toxicity is required when antimonials are used therapeutically.
Liposomal amphotericin B and leishmaniasis: Dose and response
Sundar Shyam,Chakravarty Jaya
Journal of Global Infectious Diseases , 2010,
Abstract: Liposomal amphotericin B has been used with increasing frequency to treat visceral leishmaniasis (VL). It is the treatment of choice for immunocompetent patients in the Mediterranean region and the preferred drug for HIV/VL co-infection. Although there is a regional variation in the susceptibility of the parasite a total dose of 20 mg/kg is effective in immunocompetent patients. Randomized clinical trials of liposomal amphotericin B in the treatment and secondary prophylaxis of HIV-VL coinfected patients is urgently needed to optimize treatment in this subset. With the availability of Liposomal amphotericin B at a preferential pricing in the endemic areas, short course combination therapy can become a viable alternative.
Drug resistance in leishmaniasis
Chakravarty Jaya,Sundar Shyam
Journal of Global Infectious Diseases , 2010,
Abstract: The treatment options of leishmaniasis are limited and far from satisfactory. For more than 60 years, treatment of leishmaniasis has centered around pentavalent antimonials (Sb v ). Widespread misuse has led to the emergence of Sb v resistance in the hyperendemic areas of North Bihar. Other antileishmanials could also face the same fate, especially in the anthroponotic cycle. The HIV/ visceral leishmaniasis (VL) coinfected patients are another potential source for the emergence of drug resistance. At present no molecular markers of resistance are available and the only reliable method for monitoring resistance of isolates is the technically demanding in vitro amastigote-macrophage model. As the armametrium of drugs for leishmaniasis is limited, it is important that effective monitoring of drug use and response should be done to prevent the spread of resistance. Regimens of simultaneous or sequential combinations should be seriously considered to limit the emergence of resistance.
BV regularity near the interface for nonuniform convex discontinuous flux
Shyam Sundar Ghoshal
Mathematics , 2015,
Abstract: In this paper, we discuss the total variation bound for the solution of scalar conservation laws with discontinuous flux. We prove the smoothing effect of the equation forcing the $BV_{loc}$ solution near the interface for $L^\infty$ initial data without the assumption on the uniform convexity of the fluxes made as in [1,21]. The proof relies on the method of characteristics and the explicit formulas.
SO2 Oxidation Efficiency Patterns during an Episode of Plume Transport over Northeast India: Implications to an OH Minimum  [PDF]
Timmy Francis, Shyam Sundar Kundu, Ramabadran Rengarajan, Arup Borgohain
Journal of Environmental Protection (JEP) , 2017, DOI: 10.4236/jep.2017.810071
Abstract: Systematic monitoring of the fluctuations in atmospheric SO2 oxidation efficiency—measured as a molar ratio of SO42- to total SOx (SOx=SO2+SO42-), referred as S-ratio—have been performed during a major long range plume transport to northeast India (Shillong: 25.67°N, 91.91°E, 1064 m ASL) in March 2009. Anomalously low S-ratios (median, 0.03) were observed during the episode—associated with a cyclonic circulation—and the SO42- and SO2 exhibited unusual features in the ‘relative phase’ of their peaks. During initial days, when SO2 levels were dictated by the long range influx, the SO42- and SO2 variabilities were in anti-phase—for the differing mobility/loss mechanisms. When SO2 levels were governed by the boundary layer diurnality in the latter days, the anti-phase is explained by a ‘depleted OH level’—major portion being consumed in the initial period by the elevated SO2 and other pollutants. Simulations with a global 3D chemical transport model, GEOS-Chem (v8-03-01), also indicated ‘suppressed oxidation conditions’—with characteristic low S-ratios and poor phase agreements. The modelled OH decreased steadily from the initial days, and OH normalized to SO2—referred as OHspecific—was consistently low during the ‘suppressed S-ratio period’. Further, the geographical distribution of modelled OH showed a pronounced minimum over the region surrounding (20°N, 95°E) spanning parts of northeast India and the adjacent regions to the southeast of it—prevalent throughout the year, though the magnitude and the area of influence have a seasonality to it—with significant implications for reducing the oxidizing power of the regional atmosphere. A second set of measurements during January 2010—when prominent long range transports were absent—exhibited no anomalies, and the S-ratios were well within the acceptable limits (median, 0.32). This work highlights the GEOS-Chem model skill in simulating/detecting the ‘transient fluctuations’ in the oxidation efficiency, down to a regional scale.
Disease survey of Safed Musli (Chlorophytum borivilianum) in zone IVa and V of Rajasthan
KALP VERMA* and SHYAM SUNDAR SHARMA
Indian Phytopathology , 2011,
Abstract:
Case Study of Survival Function under Strength Attenuation of System for Exponential Distribution
Dr.Thaduru Shyam Sundar
International Journal on Computer Science and Engineering , 2012,
Abstract: In this paper an expression for the reliability of a single component system is derived when the strength of the component and the imminent stresses on the system are random and follow non-identical Probability distribution. Tabulated some numerical values for different values of the parameter and also for the system which are presented graphically.
SOLiD? Sequencing of Genomes of Clinical Isolates of Leishmania donovani from India Confirm Leptomonas Co-Infection and Raise Some Key Questions
Neeloo Singh, Surendra Chikara, Shyam Sundar
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0055738
Abstract: Background Known as ‘neglected disease’ because relatively little effort has been applied to finding cures, leishmaniasis kills more than 150,000 people every year and debilitates millions more. Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Whole genome analysis presents an excellent means to identify new targets for drugs, vaccine and diagnostics development, and also provide an avenue into the biological basis of parasite virulence in the L. donovani complex prevalent in India. Methodology/Principal Findings In our presently described study, the next generation SOLiD? platform was successfully utilized for the first time to carry out whole genome sequencing of L. donovani clinical isolates from India. We report the exceptional occurrence of insect trypanosomatids in clinical cases of visceral leishmaniasis (Kala Azar) patients in India. We confirm with whole genome sequencing analysis data that isolates which were sequenced from Kala Azar (visceral leishmaniasis) cases were genetically related to Leptomonas. The co-infection in splenic aspirate of these patients with a species of Leptomonas and how likely is it that the infection might be pathogenic, are key questions which need to be investigated. We discuss our results in the context of some important probable hypothesis in this article. Conclusions/Significance Our intriguing results of unusual cases of Kala Azar found to be most similar to Leptomonas species put forth important clinical implications for the treatment of Kala Azar in India. Leptomonas have been shown to be highly susceptible to several standard leishmaniacides in vitro. There is very little divergence among these two species viz. Leishmania sp. and L. seymouri, in terms of genomic sequence and organization. A more extensive perception of the phenomenon of co-infection needs to be addressed from molecular pathogenesis and eco-epidemiological standpoint.
Performance Improvement of Heterogeneous Wireless Networks using Modified Newton Method
R. Shyam Sundar,S. Nanda Kumar
Computer Science , 2012, DOI: 10.5121/ijsea.2012.330
Abstract: The heterogeneous wireless networks where coexistence of different Radio access technology (RAT) are widely deployed for various services and support various traffic demand, channel allocation. Under heterogeneous wireless networks, a user can send data through a single or multi RATs simultaneous. The objective of this paper is to choose the optimal bandwidth for the services and power allocation to that bandwidth. The proposed distributed joint allocation algorithm using modified Newton method is adopted to maximize the total system capacity. We validate the performance of the proposed algorithm through numerical results.
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