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Search Results: 1 - 10 of 36942 matches for " Shuli Zhao "
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2+2 Program for Teachers’ Performance Appraisal in China
Shuli Zhao
English Language Teaching , 2009, DOI: 10.5539/elt.v2n2p60
Abstract: This study examined the impact of the 2+2 Alternative Teacher Performance Appraisal System that has been implemented in Shanxi province in China. A mixed research design was used to evaluate the program. Six high schools and a total of 78 teachers (13 teachers in each school) in Shanxi province were selected. Three of the schools participated in the 2+2 program while another three served as the comparison. The results showed that 2+2 program significantly improved teachers’ professional performance, enhanced teachers’ collaboration, and increased the feedback between the peers.
Uniform Convergence and Transitive Subsets
Lei Liu,Shuli Zhao,Hongliang Liang
Discrete Dynamics in Nature and Society , 2012, DOI: 10.1155/2012/970934
Abstract: Let (,) be a metric space and a sequence of continuous maps ∶→ that converges uniformly to a map . We investigate the transitive subsets of whether they can be inherited by or not. We give sufficient conditions such that the limit map has a transitive subset. In particular, we show the transitive subsets of that can be inherited by if converges uniformly strongly to .
Quality Analysis on the Engineering Master of Biotechnology Specialty from Enterprise  [PDF]
Xinglin Li, Yang Han, Aijie Cao, Jun Zhao, Liming Zhang, Shuli Man, Wenyuan Gao
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.37B022
Abstract: In order to express the engineering master’s culture status of biotechnology from some enterprises, by questionnaire, 27 engineering masters from some enterprises and 22 academic masters from two universities, were investigated on the graduate students’ origin, their tutors’ title, the enterprise size and classify, their dissertation theme emphasis and classify, and the experiment condition for their dissertations. The results indicated that, the engineering masters were better than the academic masters on the practice condition and the practice chances, whereas, the academic masters markedly excelled the engineering masters on the tutors’ level, the test condition, and the innovation environment of science and technology.
A conjugate of an anti-midkine single-chain variable fragment to doxorubicin inhibits tumor growth
Zhao, Shuli;Zhao, Guangfeng;Xie, Hao;Huang, Yahong;Hou, Yayi;
Brazilian Journal of Medical and Biological Research , 2012, DOI: 10.1590/S0100-879X2012007500009
Abstract: doxorubicin (dox) was conjugated to a single-chain variable fragment (scfv) against human midkine (mk), and the conjugate (scfv-dox) was used to target the chemotherapeutic agent to a mouse solid tumor model in which the tumor cells expressed high levels of human mk. the his-tagged recombinant scfv was expressed in bacteria, purified by metal affinity chromatography, and then conjugated to dox using oxidative dextran (dex) as a linker. the molecular formula of this immunoconjugate was scfv(dex)1.3(dox)20. in vitro apoptosis assays showed that the scfv-dox conjugate was more cytotoxic against mk-transfected human adenocarcinoma cells (bgc823-mk) than untransfected cells (55.3 ± 2.4 vs 22.4 ± 3.8%) for three independent experiments. nude mice bearing bgc823-mk solid tumors received scfv-dox or equivalent doses of scfv + dox for 2 weeks and tumor growth was more effectively inhibited by the scfv-dox conjugate than by scfv + dox (51.83% inhibition vs 40.81%). histological analysis of the tumor tissues revealed that the highest levels of dox accumulated in tumors from mice treated with scfv-dox and this resulted in more extensive tumor cell death than in animals treated with the equivalent dose of scfv + dox. these results show that the scfv-dox conjugate effectively inhibited tumor growth in vivo and suggest that antigen-specific scfv may be competent drug-carriers.
Effects of Different Nitrogen Applications on Soil Physical, Chemical Properties and Yield in Maize (Zea mays L.)  [PDF]
Heng Zhong, Qiao Wang, Xinhua Zhao, Qi Du, Yue Zhao, Xiaoguang Wang, Chunji Jiang, Shuli Zhao, Minjian Cao, Haiqiu Yu, Dawei Wang
Agricultural Sciences (AS) , 2014, DOI: 10.4236/as.2014.514155
Abstract: Application of nitrogen (N) fertilizer is one of the most important approaches on improving maize grain yield. However, as is known to all, overuse N fertilizer not only leads to decline of N use efficiency and maize yield, but also leads to potential risk to environment pollution. This experiment was conducted to determine the effects of N fertilizer applications with nine different treatments on soil physical-chemical characters and maize grain yield using hybrid variety Zhengdan 958 in 2011 and 2012. Results indicated that the soil bulk densities of T2 (CK) and T1 were the lowest compared to other treatments in 2011 and 2012, respectively, whereas the soil bulk density of T5 in 2011 and T3 in 2012 were higher than other treatments. The soil porosity and field capacity of T5 in 2011 and T3 in 2012 were lower than other treatments, but those of CK in 2011 and T1 in 2012 were higher than other treatments. The pH values of T3 to T7 were lower than other treatments. These results indicated that the soil bulk densities were increased, whereas the soil porosity, field capacity and values pH were decreased by N application at different stages. N application could increase the N contents of leaf and stem, whereas less or excess N application should not significant improve maize yield. Although the soil organic matter and total N contents of T3 were the highest in both 2011 and 2012, the yield of T4 is the highest in both 2011 and 2012. The application amount, period and times of N fertilizer were important to maize yield.


Earnings management and the quality of the financial reporting
Ingrid Shuli
Perspectives of Innovations, Economics and Business , 2011,
Abstract: During the last time in the development of the financial reporting and frauds there have emerged several problems related to the quality of several indicators on the financial statements and especially the quality of the earnings indicator. According to the literature on the financial reporting it results that companies have the possibility to smooth earnings or manage earnings as a tool to avoid reporting a loss. While the economic entities are using the national and international accounting standards, the working practice of accountants/auditors shows episodes of the management of the earnings. One of the conclusions of this paper is that there is not enough information among accounting professionals regarding the practices of the earnings management. One of the recommendations is to include issues of fair and ethical reporting in the modules of the faculty of economics especially on the master level.Based on the many studies of this issue in other countries, this paper will show if this phenomenon is known in Albania and furthermore how important it is for the quality of the financial reporting in Albania. In order to achieve this objective it has been done a review of related studies. Because of the new legislation on the financial reporting being implemented in our country the recommendations of this paper may be valuable to the enforcement of the accounting standards mechanisms.
Clustered microRNAs' coordination in regulating protein-protein interaction network
Xiongying Yuan, Changning Liu, Pengcheng Yang, Shunmin He, Qi Liao, Shuli Kang, Yi Zhao
BMC Systems Biology , 2009, DOI: 10.1186/1752-0509-3-65
Abstract: Integrating of miRNA cluster information with protein protein interaction (PPI) network data, our research supports the hypothesis of the functional coordination of clustered miRNAs and links it to the topological features of miRNAs' targets in PPI network. Specifically, our results demonstrate that clustered miRNAs jointly regulate proteins in close proximity of the PPI network. The possibility that two proteins yield to this coordinated regulation is negatively correlated with their distance in PPI network. Guided by the knowledge of this preference, we found several network communities enriched with target genes of miRNA clusters. In addition, our results demonstrate that the variance of this propensity can also partly be explained by protein's connectivity and miRNA's conservation.In summary, this work supports the hypothesis of intra-cluster coordination and investigates the extent of this coordination.MicroRNAs (miRNAs) are small (22 nt) single-stranded non-coding RNA (ncRNA) molecules. They are processed from hairpin precursors of approximately 70 nt (pre-miRNAs), which in turn are extracted from primary transcripts (pri-miRNA) [1,2]. miRNAs can repress gene expression post-transcriptionally by binding to the 3' untranslated regions (3' UTRs) of their target mRNAs [3-5]. In animal genomes, miRNAs are found in various genomic locations; while most are located in intergenic regions, some are found to be hosted within the introns of pre-mRNAs or within longer ncRNA genes [6,7]. Interestingly, known miRNA genes, both hosted and non-hosted, are often observed to be clustered [8]. A cluster usually includes two or three miRNA genes, but larger clusters have also been identified, including a human mir-17 cluster comprising 6 miRNA genes and a human mir-302 cluster comprising 8 miRNA genes. Baskerville and Bartel found that miRNAs within 50 Kb are highly correlated in expression across 24 different human organs, indicating that 50 Kb might be used as preliminary defi
Conflict between Role of Editors, Writers and Readers and Replacement of Each Other''s Role in Sci-tech Journals
科技期刊编辑中的角色冲突与角色替换

ZHAO Yang,MA ShuLi,LI TianHeng,
赵洋
,马述立,李天恒

中国科技期刊研究 , 2006,
Abstract: 采用社会学中角色冲突和角色替换理论,分析和探讨了科技编辑在文稿的审读和编辑加工过程中,如何实现编辑、作者和读者这三种角色的替换和融合,通过三种角色的替换使编辑对稿件做出恰当的修改,以达到最佳的编审效果。
The Effect of MUC1 rs4072037 Functional Polymorphism on Cancer Susceptibility: Evidence from Published Studies
Fujiao Duan, Chunhua Song, Liping Dai, Shuli Cui, Xiaoqin Zhang, Xia Zhao
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0095651
Abstract: Genome-wide association studies have identified a susceptibility variation MUC1 rs4072037 for gastric cancer in Chinese population. Subsequent case-control studies have reported this association in other populations. However, the results remain controversial and ambiguous. The aim of this study is to provide a precise quantification for the association between MUC1 rs4072037 variation and the risk of cancer. We performed pooled analysis of 10 case-control designed studies including 4,220 cases and 6,384 controls. Odds ratios (OR) and 95% confidence interval (95%CI) were calculated to assess strength of association in overall studies and in subgroup analysis stratified by ethnicity and cancer types. All statistical analyses were performed by Manager 5.0 and Stata 12.0 software. Overall, the MUC1 rs4072037 polymorphism was associated with risk of cancer in all genetic models (G vs A: OR = 0.71, 95%CI: 0.63–0.80, p<0.01; GA vs AA: OR = 0.61, 95%CI:0.55–0.67, p<0.01; GG vs AA: OR = 0.58, 95%CI: 0.47–0.71, p<0.01; AG+AA vs GG: OR = 0.60, 95%CI: 0.55–0.60, p<0.01; GG vs AG+AA: OR = 0.70, 95%CI: 0.58–0.85, p<0.01). Further, subgroup analysis based on ethnicity suggested MUC1 rs4072037 polymorphism had a subtly reduced cancer risk among Asian population, and stratified analysis by cancer types showed significantly decreased risk of gastric cancer in all genetic models. In conclusion, MUC1 rs4072037 polymorphism may be used as potential biomarker for cancer susceptibility particularly for gastric cancer and for Asian population.
The Significance of Exo1 K589E Polymorphism on Cancer Susceptibility: Evidence Based on a Meta-Analysis
Fujiao Duan, Chunhua Song, Liping Dai, Shuli Cui, Xiaoqin Zhang, Xia Zhao
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0096764
Abstract: The exonuclease1 (Exo1) gene is a key component of mismatch repair (MMR) by resecting the damaged strand, which is the only exonuclease involved in the human MMR system. The gene product is a member of the RAD2 nuclease family and functions in DNA replication, repair and recombination. However, whether Exo1 is required to activate MMR-dependent DNA damage response (DDR) remains unknown, the conclusions of the Exo1 polymorphisms on cancer susceptibility studies were not consistent. We carried out a meta-analysis of 7 case-control studies to clarify the association between the Exo1 K589E polymorphism and cancer risk. Overall,a significant association of the Exo1 K589E polymorphism with cancer risk in all genetic models (Lys vs Glu: OR = 1.51, 95%CI:1.39–1.99, P<0.01; Glu/Lys vs Glu/Glu: OR = 1.43, 95%CI:1.28–1.60, P<0.01; Lys/Lys vs Glu/Glu: OR = 2.45, 95%CI:1.90–3.17, P<0.01; Lys/Lys+Glu/Lys vs Glu/Glu: OR = 1.53, 95%CI:1.38–1.71, P<0.01; Glu/Glu vs Glu/Lys+Lys/Lys: OR = 2.27, 95%CI:1.79–2.89, P<0.01). In the stratified analysis by ethnicity, significantly increased risk was observed in Asian population (Lys vs Glu: OR = 1.53, 95%CI:1.39–1.69, P<0.01; Glu/Lys vs Glu/Glu: OR = 1.50, 95%CI:1.34–1.69, P<0.01; Lys/Lys vs Glu/Glu: OR = 2.48, 95%CI:1.84–3.34, P<0.01; Lys/Lys+Glu/Lys vs Glu/Glu: OR = 1.58, 95%CI:1.41–1.78, P<0.01; Glu/Glu vs Glu/Lys+Lys/Lys: OR = 2.18, 95%CI:1.62–2.93, P<0.01). Subgroup analysis based on smoking suggested Exo1 K589E polymorphism conferred significant risk among smokers (Lys/Lys+Glu/Lys vs Glu/Glu: OR = 2.16, 95%CI:1.77–2.63, P<0.01), but not in non-smokers (Lys/Lys+Glu/Lys vs Glu/Glu: OR = 0.89, 95%CI:0.64–1.24, P = 0.50). In conclusion, Exo1 K589E Lys allele may be used as a novel biomarker for cancer susceptibility, particularly in smokers.
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