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Search Results: 1 - 10 of 468 matches for " Sho Hidaka "
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Interaction between Peptide Pheromone or Its Truncated Derivatives and Pheromone Receptor of the Fission Yeast Schizosaccharomyces pombe Examined by a Force Spectroscopy Study and a GFP Reporter Assay  [PDF]
Sho Hidaka, Osamu Nikaido, Shoichi Kiyosaki, Atsushi Ikai, Toshiya Osada
Journal of Surface Engineered Materials and Advanced Technology (JSEMAT) , 2013, DOI: 10.4236/jsemat.2013.34A1005
Abstract:

In our previous study, the specific interaction between P-factor, a peptide pheromone and its receptor, Mam2, on the cell surface of the fission yeast Schizosaccharomyces pombe was investigated by two methods, an atomic force microscope (AFM) and a GFP reporter assay. The removal of Leu at C-terminal of P-factor resulted in an inactivation of P-factor function to bind Mam2 and induce the signal transduction pathway. Here, we used truncated P-factor derivatives lacking N-terminal of P-factor (P12 ~ P22: 12 ~ 22 amino acid residues from C-terminal) as ligands for Mam2. From the dose-dependent analysis of the GFP reporter assay ranging from 1 nM to 100 μM of the peptide concentration, the peptides can be classified into three groups based on EC50 and maximal GFP production level, group1 (P-factor), group2 (P17 ~ 22), and group3 (P12 ~ P16). At 0.1 μM, only P-factor induced the signal transduction pathway. At 1 μM, peptides from group2 partially induced the pathway and peptides from group3 induced the pathway a little. At 10 μM, all peptides induced the pathway mostly depending on the length of peptides. We also performed AFM experiments using P-factor and peptides from group3 to investigate the interaction between the peptides and Mam2 for comparison between the two methods.

Selection of Suitable Safety Activities and Experience of Safety Condition Establishment  [PDF]
Akihiko Hidaka, Atsumi Miyake
Open Journal of Safety Science and Technology (OJSST) , 2015, DOI: 10.4236/ojsst.2015.51001
Abstract: In recent years, Japanese manufacturing firms have been building factories in the developing countries of Southeast Asia and employing local personnel. Using local employees who were basically people of the agricultural countries implies difficulties in both technical and safety terms. This study examines how quickly and effectively the companies going into the developing countries establish a standard of safety. The authors focus on Vietnam and Thailand as representative countries. To their surprise, the authors find that all 27 companies that answered their questionnaire had introduced “5S activities” at startup and were continuing to use them. In addition, nearly 80% of the companies began using “KY activities”, “Safety proposal activities”, and “Examinations of accidents” soon after startup. One of the authors Akihiko Hidaka, when serving as the president of the Thai subsidiary of a Japanese chemical company, developed safety activities to reduce work-related accidents. And he knew that the kinds of safety activities he developed were same as above 4 activities. So he evaluated these activities and judged them to be effective. The authors conclude that “5S activities”, “KY activities”, “Safety proposal activities”, and “Examinations of accidents” were the activities best able to improve safety effectively and quickly in developing countries. The authors describe the safety activities carried out at the Thai company and then describe the most important features of the methods used to establish safety conditions at the firm.
Impact of slepton generation mixing on the search for sneutrinos
Hidaka, K.
High Energy Physics - Phenomenology , 2008,
Abstract: We perform a systematic study of sneutrino production and decays in the Minimal Supersymmetric Standard Model (MSSM) with lepton flavour violation (LFV). We study bosonic decays of sneutrinos as well as fermionic ones. We show that the effect of slepton generation mixing on the sneutrino production and decays can be quite large in a significant part of the MSSM parameter space despite the very strong experimental limits on LFV processes. This could have an important impact on the search for sneutrinos and the determination of the MSSM parameters at LHC and future colliders, such as ILC, CLIC and muon collider.
Impact of slepton generation mixing on the search for sneutrinos - Lepton flavour violation in sneutrino production and decays in the general MSSM
Hidaka, K.
High Energy Physics - Phenomenology , 2007,
Abstract: We perform a systematic study of sneutrino production and decays in the Minimal Supersymmetric Standard Model (MSSM) with slepton generation mixing. We study bosonic decays like sneutrino \to slepton^- + W^+/H^+ as well as fermionic ones. We show that the effect of slepton generation mixing on the sneutrino production and decays can be quite large in a significant part of the MSSM parameter space despite the very strong experimental limits on lepton flavour violating processes. This could have an important impact on the search for sneutrinos and the determination of the MSSM parameters at future colliders, such as LHC, ILC, CLIC and muon collider.
A Computational Model Associating Learning Process, Word Attributes, and Age of Acquisition
Shohei Hidaka
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076242
Abstract: We propose a new model-based approach linking word learning to the age of acquisition (AoA) of words; a new computational tool for understanding the relationships among word learning processes, psychological attributes, and word AoAs as measures of vocabulary growth. The computational model developed describes the distinct statistical relationships between three theoretical factors underpinning word learning and AoA distributions. Simply put, this model formulates how different learning processes, characterized by change in learning rate over time and/or by the number of exposures required to acquire a word, likely result in different AoA distributions depending on word type. We tested the model in three respects. The first analysis showed that the proposed model accounts for empirical AoA distributions better than a standard alternative. The second analysis demonstrated that the estimated learning parameters well predicted the psychological attributes, such as frequency and imageability, of words. The third analysis illustrated that the developmental trend predicted by our estimated learning parameters was consistent with relevant findings in the developmental literature on word learning in children. We further discuss the theoretical implications of our model-based approach.
Model study of the sign problem in a mean-field approximation
Yoshimasa Hidaka
Physics , 2007,
Abstract: We study the sign problem of the fermion determinant at nonzero baryon chemical potential. For this purpose we apply a simple model derived from Quantum Chromodynamics, in the limit of large chemical potential and mass. For SU(2) color, there is no sign problem and the mean-field approximation is similar to data from the lattice. For SU(3) color the sign problem is unavoidable, even in a mean-field approximation. We apply a phase-reweighting method, combined with the mean-field approximation, to estimate thermodynamic quantities. We also investigate the mean-field free energy using a saddle-point approximation.
Impact of slepton generation mixing on the search for sneutrinos - Lepton flavour violation in sneutrino production and decays in the general MSSM
K. Hidaka
Physics , 2007,
Abstract: We perform a systematic study of sneutrino production and decays in the Minimal Supersymmetric Standard Model (MSSM) with slepton generation mixing. We study bosonic decays like sneutrino \to slepton^- + W^+/H^+ as well as fermionic ones. We show that the effect of slepton generation mixing on the sneutrino production and decays can be quite large in a significant part of the MSSM parameter space despite the very strong experimental limits on lepton flavour violating processes. This could have an important impact on the search for sneutrinos and the determination of the MSSM parameters at future colliders, such as LHC, ILC, CLIC and muon collider.
Impact of squark generation mixing on the search for gluinos at LHC
K. Hidaka
Physics , 2010, DOI: 10.1063/1.3327606
Abstract: We study the effect of squark-generation mixing on gluino decays in the Minimal Supersymmetric Standard Model (MSSM). We show that due to the effect the quark-flavor violating (QFV) gluino decay branching ratio B(gluino -> c bar{t} (t bar{c}) + neutralino_1) can be very large (up to ~50%) in a significant part of the MSSM parameter space despite the very strong experimental constraints on QFV from B meson observables. This could have an important impact on the search for gluinos and the determination of the MSSM parameters at LHC.
Counting rule for Nambu-Goldstone modes in nonrelativistic systems
Yoshimasa Hidaka
Physics , 2012, DOI: 10.1103/PhysRevLett.110.091601
Abstract: The counting rule for Nambu-Goldstone modes is discussed using Mori's projection operator method in nonrelativistic systems at zero and finite temperatures. We show that the number of Nambu-Goldstone modes is equal to the number of broken charges, Q_a, minus half the rank of the expectation value of [Q_a,Q_b].
Large Squark-Mixing Impact on H^+ Decay in the MSSM
K. Hidaka
Physics , 1997,
Abstract: We study the decays of the charged Higgs boson H^+ within the Minimal Supersymmetric Standard Model. We find that the supersymetric mode 'stop + sbottom-bar' can dominate the H^+ decays in a wide range of the model parameters due to the large Yukawa couplings and mixings of stop and sbottom. Compared to the conventional modes 'tau^+ nu' and 't b-bar', this mode has very distinctive signatures. This could have a decisive impact on H^+ searches at future colliders. We find also that the QCD corrections to the 'stop + sbottom-bar' mode are significant, but that they do not invalidate our tree-level conclusion above.
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