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COUPLED COINSIDENCE POINT THEOREM FOR NONLINEAR CONTRACTION IN PARTIALLY ORDERED METRIC SPACES
Kiramkumar Laxmanrao Bondar,Arun B Jadhao,Shivaji T Patil
Journal of Global Research in Mathematical Archives , 2013,
Abstract: The existence theorem of coupled coincidence point is proved. The main tool in the proof of result combines the ideas in the contraction principle with those in the monotonic iterative technique. An example is given satisfying.
“DISTRIBUTION AND GROWTH OF RURAL SETTLEMENTS: A CASE STUDY OF DHULE DISTRICT (M.S.)”.
SHIVAJI B. PATIL,RISHIKESH SUBHASH CHITTAM
Golden Research Thoughts , 2012, DOI: 10.9780/22315063
Abstract: The present paper focused on the growth and distribution of rural settlements in the study area from 1981 to 2001. There are 678 (2001) villages in the district. These villages are unevenly distributed over the area of 8063.11sq.kms. The district is a part of Northern Maharashtra. It contributes 2.62% total geographical area of the Maharashtra state. Dhule district includes four tehsil namely Dhule, Sakri, Shindkheda and Shirpur. Dhule distinct forms a district geographical unit, as it is occupied by 'Satpuda' ranges in the north. 'Satmala' in the south and central part is occupied by River Tapi basin with her major tributaries like Panzara, Burai and Arunamati.
Economics Of Organic Farming : A Case Study Of Dhule District(M.S.)
Shivaji B. Patil,Pawar Vishal S.
Indian Streams Research Journal , 2012,
Abstract: The present paper is to investigate the economics of organic farming .the concept of organic farming or natural farming came forward from Asian countries .this art of farming already preserved and cultivated by Indian and Chinese farmer. Before the invention of chemical fertilizer farming is cultivated in organic farming way. even today the organic farming is increased all over the world due to environment point of view , health point of view and as well as economic point of view. Thus in the present paper it is find out economical benefit of organic farming with compare to chemical farming
Edge-Detection in Noisy Images Using Independent Component Analysis
Kaustubha Mendhurwar,Shivaji Patil,Harsh Sundani,Priyanka Aggarwal,Vijay Devabhaktuni
ISRN Signal Processing , 2011, DOI: 10.5402/2011/672353
Abstract: Edges in a digital image provide important information about the objects contained within the image since they constitute boundaries between objects in the image. This paper proposes a new approach based on independent component analysis (ICA) for edge-detection in noisy images. The proposed approach works in two phases—the training phase and the edge-detection phase. The training phase is carried out only once to determine parameters for the ICA. Once calculated, these ICA parameters can be employed for edge-detection in any number of noisy images. The edge-detection phase deals with transitioning in and out of ICA domain and recovering the original image from a noisy image. Both gray scale as well as colored images corrupted with Gaussian noise are studied using the proposed approach, and remarkably improved results, compared to the existing edge-detection techniques, are achieved. Performance evaluation of the proposed approach using both subjective as well as objective methods is presented. 1. Introduction In typical images, edges characterize the object boundaries with sharp changes in intensity levels. Edges are useful for segmentation, registration, and identification of objects in a given scene. Most of these operations have edge-detection as the preprocessing step. Consequently, the success of these image processing tasks depends strictly on the performance of edge-detection step. Detection of these edges, therefore, not only helps in more accurate representation of an image, but it also significantly simplifies its processing. The edge detection usually involves calculation of derivative of the image intensity function at a given pixel location owing to the fact that image intensity shows sudden changes at edges. Pixels with relatively higher magnitude of derivative of the image intensity function are classified into edge pixels. To this end, Gradient and Laplacian operators/masks such as Prewitt, Roberts, Sobel, Canny [1–3] are usually employed for the purpose of edge-detection. These operators work well for specific cases; however, they fail for others. For instance, the Prewitt edge detector works quite well for digital images corrupted with Poisson noise, whereas its performance decreases sharply for other kinds of noise [4]. Moreover, these operators/masks are chosen independent of the image under consideration. As such, the performance of these operators masks degrades considerably with the increase in noise levels in images [2]. Unfortunately, digital images are inevitably degraded by noise during acquisition and/or transmission.
HPTLC DETERMINATION OF SORAFENIB TOSYLATE IN BULK DRUG AND PHARMACEUTICAL DOSAGE FORM
Powar Amol Shivaji,Gowda Pramila T
International Research Journal of Pharmacy , 2012,
Abstract: A simple and sensitive HPTLC method has been developed for the quantitative estimation of Sorafenib Tosylate in bulk and Pharmaceutical dosage form. Sorafenib Tosylate was chromatographed on silica Gel 60 F254 TLC plate using n-Hexane : isopropanol (8:2 v/v) as mobile phase. Sorafenib Tosylate showed Rf value 0.34±0.05 and scanned at 254 nm using Camag TLC Scanner 3. The method was validated in terms of linearity (100–500 ng/spot), precision (intra-day % RSD variation 0.07 to 0.39%, inter-day % RSD variation 0.5 to 1.2%), accuracy (98.88 to 100.815%) specificity, ruggedness, sensitivity and reproducibility. The limit of detection and limit of quantitation for Sorafenib Tosylate were found to be 1.57 ng/spot and 4.75 ng/spot, respectively. The developed method was successfully used for the assay of Sorafenib Tosylate in bulk and Pharmaceutical dosage form.. it can be used for the routine quality control testing of marketed formulations.
HPLC analysis of closed, open, and reflex eye tear proteins
Sitaramamma T,Shivaji S,Rao Gullapalli
Indian Journal of Ophthalmology , 1998,
Abstract: Changes in the closed, open and reflex eye tear proteins of normal subjects were compared and analysed. Tear proteins were resolved by high-performance liquid chromatography (HPLC) utilising both gel filtration (P-300 SW) and reverse-phase (C-18) columns and the HPLC fractions were further analysed by sodium dodecyl sulphate - polyacrylamide gel electrophoresis (SDS-PAGE) under reducing and non-reducing conditions. The protein composition of the closed-eye tear was significantly different from that of the open and reflex-eye tear. Secretory IgA (sIgA) was the predominant protein in closed eye tears constituting 49% of the total protein compared to 11% in reflex tears, whereas lysozyme was the predominant protein (53%) in reflex tears. Levels of lactoferrin, lipocalin and lysozyme were relatively constant in both open and reflex tears. HPLC profiles of the closed-eye tears, upon continuous stimulation of lacrimal glands indicated that sIgA was significantly reduced whereas lactoferrin, lipocalin, and lysozyme were significantly increased. These results indicate that the tear composition upon waking attains that of the open eye within 4 to 5 minutes, and upon continuous stimulation this reflects the reflex-eye tear composition. It also indicates that mechanisms responsible for changes in concentration of constitutive and regulated tear protein with stimulus can be studied successfully using non-invasive methods to collect human tears.
ORIGINAL ARTICLE: Seroprevalence of Brucellosis among Blood Donors of Satara District, Maharashtra
Smita Mangalgi,Annapurna Sajjan,Shivaji T. Mohite
Journal of Krishna Institute of Medical Sciences University , 2012,
Abstract: Backgroind: In endemic area for brucellosis background levels of antibodies are found in healthy populations. Aims & Objectives: Theaim of this study was to determine the seroprevalence of anti-brucella antibodies and base line titres among the blood donors.Materials and Methods: 321 blood samples were collected from blood donors. Serological tests - Rose Bengal Plate Agglutination Test(RBPT), Standard Tube Agglutination Test (STAT) and 2-Mercaptoethanol Agglutination Test (2ME), were carried out on all the blood samples. Results: Seroprevalence of brucellosis in blood donors was 5.91%, 3.11 % and 0.62% by RBPT, STAT and 2ME respectively. History of animal exposure and occasional raw milkingestion was observed in 137 individuals residing in rural area. Conclusion: Brucellosis might be common in rural population who comein contact with infected animals and or consume raw milk. For the diagnosis of brucellosis RBPT test should be used only for screening purpose and the positive results should be confirmed by STAT and 2ME tests. Titres of 160 IU and above for STAT and 80 IU and above for 2ME test can be considered significant for diagnostic purpose.
Climate change: The challenges for public health preparedness and response- An Indian case study
Patil Rajan,Deepa T
Indian Journal of Occupational and Environmental Medicine , 2007,
Abstract: Extremes weather changes surpassing their usual statistical ranges and tumbling records in India could be an early warning bell of global warming. Extreme weather events like the recent record setting in western Indian city of Mumbai or all time high fatalities due to the heat wave in southern Indian states or increasing vulnerability of easten Indian states to flood could all be a manifestation of climate change in the Asian subcontinent. While the skeptics may be inclined to dismiss these events as simple local aberrations, when viewed in an epidemiological paradigm in terms of person, time and space couple with frequency, intensity and fatalities, it could well be an early manifestation of climate change. Global warming poses serious challenge to the health sector and hence warrants emergency health preparedness and response. Climate-sensitive diseases are among the largest global killers, hence major brunt of global climate change in terms of adverse health impact will be mostly borne by poor and developing countries in Asia, given the levels of poverty, nutional levels and poor public health infrastructure.
SYNTHESIS AND PHARMACOLOGICAL SCREENING OF SOME BENZOXAZOLE DERIVATIVES AS AN ANTI-INFLAMMATORY AGENTS
Sunila T. Patil
International Journal of Pharmaceutical Research and Development , 2010,
Abstract: The main objective of the medicinal chemistry is to synthesize the compounds that show promising activity as therapeutic agents with lower toxicity. Benzoxazole derivatives are very useful compound with well known biological activity. Notable among these are antibacterial, antiviral ,antifungal, analgesic, anti-inflammatory and antitubercular. In the current research work, the title compounds N`[substituted sulfonyl]-1,3-benzoxazole-5-carbohydrazide, were synthesized by electrophilic aromatic substitution on p-hydroxy methyl benzoate (I) with concentrated nitric acid and concentrated sulfuric acid under reflux condition. Compound (II) on reduction with sodium dithionate with alcohol gives 3-amino-4-hydroxy-benzoic acid methyl ester (III). Reaction of compound (III) with two appropriate aliphatic acids (formic acid and acetic acid) produced corresponding 2-subtituted benzoxazole-5-carboxylic acid methyl esters. The reaction of compounds (IV) with hydrazine hydrate in ethanol on refluxing yielded the corresponding 2-substituted benzoxazole-5-carboxylic acid hydrazides. On further reaction of compounds (V) with the different sulfonyl chloride derivatives afforded the corresponding eight N`[substituted sulfonyl]-1,3-benzoxazole-5-carbohydrazide.The identification and characterization of the synthesized compounds were carried out by Elemental analysis, melting point,Thin Layer Chromatography, FT-IR, NMR and Mass data to ascertain that all synthesized compounds were of different chemical nature than the respective parent compound. The compounds were screened for anti-inflammatory activity.The antiinflammatory activity of compounds was done by using carrageenan induced rat paw edema method. The test compounds VIa, VId and VIe showed significant antiinflammatory activity compared with the standard drug Ibuprofen.
Physicochemical Analysis of Selected Groundwater Samples of Amalner Town inJalgaon District, Maharashtra, India
V. T. Patil,P. R. Patil
Journal of Chemistry , 2010, DOI: 10.1155/2010/820796
Abstract:
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