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Search Results: 1 - 10 of 124184 matches for " Shih-Chin Wang "
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Optimal Design and Control of a Torque Motor for Machine Tools  [PDF]
Yee-Pien YANG, Shih-Chin YANG, Jieng-Jang LIU
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2009, DOI: 10.4236/jemaa.2009.14033
Abstract: This paper presents a systematic approach of optimal design and control of a surface-mount, permanent-magnet synchronous torque motor for the next-generation machine tools. A step-by-step procedure of optimization integrates multiple performance objectives and constraints to help the designer make the best decision on the final motor geometry from both design and control perspectives. In the perspective of design, a torque motor with concentrated windings and similar numbers of slots and poles may achieve the desired performance after optimization for multiple objectives, leading to a sinusoidal flux density for a nearly ripple-free torque distribution. From the control perspective, an optimal current waveform with an ideal shift angle is determined for each phase by aligning the current excitation with the back electromotive force. Both design and control of the surface-mount, permanent magnet machine are verified by the finite element method, and a prototype is fabricated for performance validation.
Aqueous Extract of Paeonia suffruticosa Inhibits Migration and Metastasis of Renal Cell Carcinoma Cells via Suppressing VEGFR-3 Pathway
Shih-Chin Wang,Sai-Wen Tang,Sio-Hong Lam,Chung-Chieh Wang,Yu-Huei Liu,Hsuan-Yuan Lin,Shoei-Sheng Lee,Jung-Yaw Lin
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/409823
Abstract: Renal cell carcinoma (RCC) cells are characterized by strong drug resistance and high metastatic incidence. In this study, the effects of ten kinds of Chinese herbs on RCC cell migration and proliferation were examined. Aqueous extract of Paeonia suffruticosa (PS-A) exerted strong inhibitory effects on cancer cell migration, mobility, and invasion. The results of mouse xenograft experiments showed that the treatment of PS-A significantly suppressed tumor growth and pulmonary metastasis. We further found that PS-A markedly decreased expression of VEGF receptor-3 (VEGFR-3) and phosphorylation of FAK in RCC cells. Moreover, the activation of Rac-1, a modulator of cytoskeletal dynamics, was remarkably reduced by PS-A. Additionally, PS-A suppressed polymerization of actin filament as demonstrated by confocal microscopy analysis and decreased the ratio of F-actin to G-actin in RCC cells, suggesting that PS-A inhibits RCC cell migration through modulating VEGFR-3/FAK/Rac-1 pathway to disrupt actin filament polymerization. In conclusion, this research elucidates the effects and molecular mechanism for antimigration of PS-A on RCC cells and suggests PS-A to be a therapeutic or adjuvant strategy for the patients with aggressive RCC.
Simulations of Rayleigh’s Wave on Curved Surface  [PDF]
Shih-yu Shen, Chin-Yu Wang
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.46132
Abstract: Impulsive line load in a half-space (Lamb’s problem) can be solved with a closed form solution. This solution is helpful for understanding the phenomenon of Rayleigh’s waves. In this article, we use a boundary element method to simulate the solution of an elastic solid with a curved free surface under impact loading. This problem is considered difficult for numerical methods. Lamb’s problem is calculated first to verify the method. Then the method is applied on the problems with different surface curvatures. The method simulates the phenomenon of Rayleigh’s wave propagating on a curved surface very well. The results are shown in figures.
Steam Reforming of Ethanol over CoMg/SBA-15 Catalysts  [PDF]
Josh Y. Z. Chiou, Shih-Yi Yang, Chin-Liang Lai, Hsuan-Ying Kung, Chih-Wei Tang, Chen-Bin Wang
Modern Research in Catalysis (MRC) , 2013, DOI: 10.4236/mrc.2013.22A003
Abstract:

Hydrogen production through steam reforming of ethanol (SRE) over Mg modified Co-based catalysts supported on mesoporous SBA-15 was studied herein to evaluate the catalytic activity and the behavior of coke deposition. The CoyMgx/SBA-15 catalysts are obtained according to the steps of consecutive impregnation of Mg (x = 5 and 10 wt%) to be incorporated on SBA-15 and then follow the loading of Co (y = 10 and 20 wt%) using the incipient wetness impregnation method. The catalysts are characterized by using X-ray diffraction (XRD), temperature programmed reduction (TPR), transmission electron microscopy (TEM) and BET techniques. Also, the spent catalysts are further characterized by using XRD and TEM. The catalytic activity of the SRE is evaluated in a fixed-bed reactor under 22,000 h-1 GHSV and with an H2O/EtOH molar ratio of 13. All the CoyMgx/SBA-15 catalysts present a mesoporous structure, even after the SRE reaction. The optimum catalyst of Co20Mg5/SBA-15-H650 comes from the high loading of Co and high reduction temperature pretreatment, which show a high catalytic activity and stability at 550°C with a hydrogen yield (YH2) up to 5.78 and CO selectivity around 3.10%.

Iterative methodology to improve the resources utilization rate of a production system
Chin Shih
Sistemas & Gest?o , 2007,
Abstract: The management of production resources is an important activity to acquire competitiveadvantage, which its goal is to integrate the equipments aiming at attending the demand witha lower final product price. This paper presents a typical issue in production resourcesmanagement which when extra capacity of bottleneck equipment is added, it generates oversizing and therefore idle. In addict to this, this decision may transfer the bottleneck to otherequipments. A model in discrete simulation in Arena 5.0 is constructed and executed tomonitor the bottleneck formation, based on the information of the utilization rate. Next, it ispresented in this paper an iterative methodology to improve the utilization rates of allequipments, obtained from the mathematical modeling of balancing elements which passthrough the production system. This methodology can be easily implemented inprogramming software Pascal 7.0.
Metodologia iterativa para melhorar a taxa de utiliza o dos recursos de um sistema produtivo
Chin Shih
Sistemas & Gest?o , 2009,
Abstract: A administra o dos recursos produtivos é uma atividade importante para adquirir vantagem competitividade, cuja fun o é integrar os equipamentos visando atender a demanda e ao menor pre o final do produto. Este artigo apresenta um problema típico em administra o de recursos produtivos em que disponibilizar capacidades extras de equipamentos gargalo geram superdimensionamento e portanto ociosidade. Entretanto esta atitude pode transferir o ponto gargalo para outros equipamentos. Um modelo de simula o discreta em Arena 5.0 é construído e executado para monitorar a forma o de gargalo, baseado nas informa es das taxas de utiliza o. Em seguida, é apresentada neste artigo uma metodologia iterativa que melhore a taxa de utiliza o de todos os equipamentos, obtida a partir de uma modelagem matemática de balanceamento de elementos que percorrem o sistema produtivo. Esta metodologia pode ser facilmente implementada em uma linguagem de programa o Pascal 7.0.
The Properties of Sintered Calcium Phosphate with [Ca]/[P] = 1.50
I-Ming Hung,Wei-Jen Shih,Min-Hsiung Hon,Moo-Chin Wang
International Journal of Molecular Sciences , 2012, DOI: 10.3390/ijms131013569
Abstract: In order to obtain the properties of the sintered as-dried calcium phosphate with [Ca]/[P] = 1.50, the characteristics of sintered pellets have been investigated using X-ray diffraction (XRD), inductively coupled plasma-mass spectrometry (ICP-MS), Fourier-transform infrared (FT-IR) spectra, Vickers hardness indentation and scanning electron microscopy (SEM). When the pellet samples were sintered between 700 °C and 1200 °C for 4 h, the hydroxyapatite (Ca 10(PO 4) 6(OH) 2, HA) still maintained the major phase, accompanied with the rhenanite (NaCaPO 4) as the secondary phase and β-tricalcium phosphate (β-Ca 3(PO 4) 2, β-TCP) as the minor phases. In addition, the HA partially transformed to α-tricalcium phosphate (α-Ca 3(PO 4) 2, α-TCP) and tetracalcium phosphate (Ca 4(PO4) 2O, TTCP), when the pellet samples were sintered at 1300 °C and 1400 °C, respectively, for 4 h. The maximum density and Vickers Hardness (HV) of sintered pellet samples were 2.85 g/cm 3 (90.18% theoretical density (T.D.)) and 407, which appeared at 1200 °C and 900 °C, respectively.
The Influence of Self-monitoring Blood Glucose Frequency on the Oscillation of Hemoglobin A1c and Chronic Complications
I-Chin Huang,Pei-Wen Wang,Rue-Tsuan Liu,Shih-Chen Tung
Chang Gung Medical Journal , 2012,
Abstract: Background: A fluctuating blood glucose level is one of the risks of chronic complicationsin diabetes. Previous studies indicated that hemoglobin A1c (HbA1c) valuesappa r ent ly improved a f t e r ini t i a t ion of s e l f -moni tor ing blood glucos e(SMBG). The purpose of this study is to investigate the relationship betweenthe frequency of SMBG, long-term fluctuatation of HbA1c, and risks ofchronic complications in diabetes.Methods: We enrolled 1052 patients with type 2 diabetes. The mean follow-up was 4.7years. The HbA1c level and frequency of SMBG were recorded every 3months. Non-mydriatic retinal photography, semiquantitative neuropathyassessment, the lipid profile, serum creatinine level, and urine protein weremeasured at the beginning of the study and then every year. The fluctuationin HbA1c throughout the period was expressed as the standard deviations(SDs) of all measurements of the HbA1c.Results: The frequency of SMBG was significantly and negatively correlated with theSDs of the HbA1c (r = –0.553, p < 0.001) but not with the average HbA1c.After controlling for age, sex, body mass index, duration of diabetes andcomorbidities (dyslipidemia and hypertension), the correlation was stillapparent (r = –0.511, p = 0.008). Patients with progression of nephropathy,neuropathy, and retinopathy, exhibited greater fluctuation of HbA1cs (2.38 0.99 vs. 0.93 1.16, p-value 0.002; 0.97 1.59 vs. 0.90 0.56, pvalue 0.04; 0.99 1.33 vs. 0.90 0.56, p-value 0.04, respectively) and lessfrequent SMBG (3.2 2.6 vs. 4.3 3.1, p-value 0.02; 3.2 2.6 vs. 4.1 3.9, p-value 0.05; 3.0 3.1 vs. 4.2 2.8, p-value 0.01, respectively) thanpatients without progression of these complications.Conclusion: This study shows that frequent SMBG decreased the fluctuation of HbA1cand decreased microvascular complications. Decreasing fluctuation ofHbA1c may play an important role in diabetes treatment.
Hyperbaric Oxygen Therapy in the Treatment of Chronic Refractory Osteomyelitis: A Preliminary Report
Chin-En Chen,Shu-Tai Shih,Te-Hu Fu,Jun-Wen Wang
Chang Gung Medical Journal , 2003,
Abstract: Background: Hyperbaric oxygen (HBO) has been proven to enhance bone and soft tissuehealing in ischemic tissue in vitro and in vivo studies. Although only a fewreports have been proven using controlled studies, this treatment modalityremains encouraging for chronic refractory osteomyelitis. In this retrospectivestudy, we reported the clinical results of HBO therapy for chronic refractoryosteomyelitis.Methods: From January through August 2000, 14 patients with chronic refractoryosteomyelitis of the tibias treated with HBO were available for follow-upexamination. According to the Cierny-Mader classification, all patients wereclassified as type III or IV osteomyelitis. Adequate debridement and parenteralantibiotic treatment in conjunction with HBO therapy at 2.5 atmospheresabsolute for 120 minutes, and 5 days per week regimen was used inall patients. The patients were followed-up for an average of 15 months aftercompletion of HBO therapy.Results: The most common infecting microorganism was Staphylococcus aureus.Mixed infections were usually found in patients with open fractures. Theaverage number of operations before HBO therapy was 5.4 including soft tissuereconstruction in 11 patients. The average number of HBO treatmentswas 33.6 times. There were no HBO related complications. No recurrenceof infection was noted in 11 patients, which resulted in a success rate of79%.Conclusions: Hyperbaric oxygen therapy is effective and safe for chronic refractoryosteomyelitis provided that patients had received appropriate medical andsurgical management.
Analytical and Experimental Study of Residual Stresses in CFRP
Chia-Chin Chiang,Vu Van Thuyet,Shih-Han Wang,Liren Tsai
Journal of Nanomaterials , 2013, DOI: 10.1155/2013/671469
Abstract: Fiber Bragg Grating sensors (FBGs) have been utilized in various engineering and photoelectric fields because of their good environment tolerance. In this research, residual stresses of carbon fiber reinforced polymer composites (CFRP) were studied using both experimental and analytical approach. The FBGs were embedded inside middle layers of CFRP to study the formation of residual stress during curing process. Finite element analysis was performed using ABAQUS software to simulate the CFRP curing process. Both experimental and simulation results showed that the residual stress appeared during cooling process and the residual stresses could be released when the CFRP was machined to a different shape. 1. Introduction Carbon fiber composites have been widely considered as the optimal replacement material for various industrial products. For composite materials, the inherent defects could greatly hamper the reliability and durability of the resultant products. There have been many studies of embedded stress sensors, particularly for damage detection in composite materials [1, 2]. FBGs possess great compatibility with CFRP [3], and by embedding FBG inside carbon fiber composites, the residual strain of the carbon fiber composites during production could be easily monitored. Because of thermal expansion, coefficient of the elements in the composite materials is different, and the shape of the optical spectra changed during curing process. These changes induced a shift in wavelengths of the optical fiber sensors, which could be converted to residual stress [4]. In this research, residual stresses of carbon fiber reinforced polymer composites (CFRP) were studied using both experimental and analytical approach. The simulation of residual stress during cooling process was carried out using ABAQUS. Through comparison between experimental and simulation results, the formation of residual stress in the CFRP was confirmed. 2. Materials and Methods 2.1. Fiber Bragg Grating Sensors (FBG) The FBG involved was fabricated from single cladding photosensitive fiber using the side writing method. The photosensitive fiber was produced by Fibercore Co. Ltd. (PS1250/1550). The FBGs are photoimprinted in photosensitive optical fiber by 248?nm UV radiation from a KrF Excimer laser. The impulse frequency of laser is 10?Hz. Along the fiber core, the FBG has periodic refractive index modulation with a period of 1.05~1.08?μm. This resulted in a peak Bragg reflecting wavelength of 1540~1564?nm. The reflectivity of the resulting FBG was about 99% and the FWHM (Full width Half Maximum)
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