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Search Results: 1 - 10 of 127141 matches for " Shibin Li "
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Daqing Oilfield Liquid Phase Underbalanced Drilling Improving Drilling Speed Evaluation Method  [PDF]
Shibin Li, Penghao Wang, Ligang Zhang
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2015, DOI: 10.4236/jmmce.2015.31005
Abstract: Factors affecting the drilling speed are very complex, such as formation factor (layers lithology, depth, porosity and reservoir pressure), fluid density, drilling parameters (bit pressure and speed), drill types, etc. Although liquid phase underbalanced drilling technology is to increase the penetration rate and shorten the drilling cycle, there is no evaluation model currently, so we cannot evaluate which factors can have a greater impact on speed. Based on the establishment of equivalent density and improvement of ROP (Rate of Penetration) calculation model, this paper is about the application of underbalanced drilling technology to improve drilling speed multiple sizes.
Research on the Power System Fault Classification Based on HHT and SVM Using Wide-area Information  [PDF]
Yiran Guo, Changqing Li, Yali Li, Shibin Gao
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B026
Abstract: A power system fault classification method based on the Hilbert-Huang transformation (HHT) and support vector machine (SVM) is proposed in this paper. According to different types of faults taking place in area and the outer area, this paper uses HHT to extract the instantaneous amplitude and Hilbert marginal spectrum of the current signal. Then a fault classifier consisting of a series of SVM classifiers that are optimized by using cross validation method is constructed. Finally, inputting the feature vector sets that are conversed by the HHT into the fault classifier, the fault type and locate the fault area will be distinguished. The simulation results show that this approach is very effective to classify the fault type especially when the sample is small.
The genetic variation of the backcross modified lines developed from the maize line 08-641 selected by different directions  [PDF]
Lujiang Li, Yaoyu Xiong, Wensheng Chen, Yongjian Liu, Hai Lan, Haijian Lin, Kecheng Yang, Shibin Gao, Guangtang Pan
Agricultural Sciences (AS) , 2012, DOI: 10.4236/as.2012.37111
Abstract: In this study, two donaors CN962 and 8065 were used to improve the resistance to northern leaf blight of the recurrent parent inbred line 08-641 (R08). A total of 79 lines (BC2F4) were developed by a bidirectional selection based on the similarity and dissimilarity in the shape and color of seeds to R08.The genetic variation of these lines were analyzed by 44 pairs of SSR molecular markers, the result showed that a total of 272 alleles were detected in the improved lines and R08, 123 out of them were detected in the modified lines but discarded in R08. The modified line selected based on dissimialry in the shape and corlor of seeds to R08 have lower genetic similary between R08 than that between the lines selected based on similary in the shape and color of seeds and R08, and the genetic variation of these lines were wider. It concluded that when the backcross breeding were used to improve the maize inbred lines, multidirectional selection based on phenotypic value were contribute to create and keep genetic variation.
Progress in microencapsulation of stem cells

Li Ye,Shibin Wang,

生物工程学报 , 2010,
Abstract: For the regenerative therapy of refractory diseases, stem cells have become an excellent source of seed cells due to their strong self-renewal and multi-differentiation abilities. Microcapsules can provide a three-dimensional growth environment with a good immunoisolation and biocompatibility for cells, and the microencapsulation of stem cells provides a new technical support for large-scale cell culture with high activities in vitro and long-term preservation, consequently opening up a new alternative for cell transplantation. In this review, we first outlined the development of microencapsulation, then introduced the present materials and methods for the microencapsulation of stem cells and its immunoisolation, and discussed the progress in microencapsulation technology, various types of stem cell used in recent years in details. Finally, we addressed perspectives of stem cell microencapsulation technology.
Origins of 1/f noise in nanostructure inclusion polymorphous silicon films
Li Shibin,Jiang Yadong,Wu Zhiming,Wu Jiang
Nanoscale Research Letters , 2011,
Abstract: In this article, we report that the origins of 1/f noise in pm-Si:H film resistors are inhomogeneity and defective structure. The results obtained are consistent with Hooge's formula, where the noise parameter, αH, is independent of doping ratio. The 1/f noise power spectral density and noise parameter αH are proportional to the squared value of temperature coefficient of resistance (TCR). The resistivity and TCR of pm-Si:H film resistor were obtained through linear current-voltage measurement. The 1/f noise, measured by a custom-built noise spectroscopy system, shows that the power spectral density is a function of both doping ratio and temperature.
Nanoscale Footprints of Self-Running Gallium Droplets on GaAs Surface
Jiang Wu, Zhiming M. Wang, Alvason Z. Li, Mourad Benamara, Shibin Li, Gregory J. Salamo
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0020765
Abstract: In this work, the nanoscale footprints of self-driven liquid gallium droplet movement on a GaAs (001) surface will be presented and analyzed. The nanoscale footprints of a primary droplet trail and ordered secondary droplets along primary droplet trails are observed on the GaAs surface. A well ordered nanoterrace from the trail is left behind by a running droplet. In addition, collision events between two running droplets are investigated. The exposed fresh surface after a collision demonstrates a superior evaporation property. Based on the observation of droplet evolution at different stages as well as nanoscale footprints, a schematic diagram of droplet evolution is outlined in an attempt to understand the phenomenon of stick-slip droplet motion on the GaAs surface. The present study adds another piece of work to obtain the physical picture of a stick-slip self-driven mechanism in nanoscale, bridging nano and micro systems.
Analysis of alternative signaling pathways of endoderm induction of human embryonic stem cells identifies context specific differences
Shibin Mathew, Maria Jaramillo, Xinan Zhang, Li Zhang, Alejandro Soto-Gutiérrez, Ipsita Banerjee
BMC Systems Biology , 2012, DOI: 10.1186/1752-0509-6-154
Abstract: hESCs were induced towards endoderm using activin A and 4 different growth factors (FGF2 (F), BMP4 (B), PI3KI (P), and WNT3A (W)) and their combinations thereof, resulting in 15 total experimental conditions. At the end of differentiation each condition was analyzed by qRT-PCR for 12 relevant endoderm related transcription factors (TFs). As a first approach, we used hierarchical clustering to identify which growth factor combinations favor up-regulation of different genes. In the next step we identified sets of co-regulated transcription factors using a biclustering algorithm. The high variability of experimental data was addressed by integrating the biclustering formulation with bootstrap re-sampling to identify robust networks of co-regulated transcription factors. Our results show that the transition from early to late endoderm is favored by FGF2 as well as WNT3A treatments under high activin. However, induction of late endoderm markers is relatively favored by WNT3A under high activin.Use of FGF2, WNT3A or PI3K inhibition with high activin A may serve well in definitive endoderm induction followed by WNT3A specific signaling to direct the definitive endoderm into late endodermal lineages. Other combinations, though still feasible for endoderm induction, appear less promising for pancreatic endoderm specification in our experiments.Embryonic stem cells have been shown to have tremendous impact in the field of regenerative medicine because of its potential to differentiate to multiple cell types of interest. Efficient harvesting of this potential requires careful development of protocols to evolve the cells through specific signaling pathways which will induce desired lineages and properties in the differentiated phenotypes. Our primary interest lies in differentiation of human embryonic stem cells (hESCs) to insulin producing β-cells of the pancreas as a cellular transplantation strategy for diabetes mellitus. The first and perhaps the most important step in diff
Epigenetic reprogramming of embryos derived from sperm frozen at 20°C
ShiBin Chao,JianChun Li,XuanJin Jin,HaiXun Tang,GongXian Wang,GuoLan Gao
Science China Life Sciences , 2012, DOI: 10.1007/s11427-012-4309-8
Abstract: Cryopreservation of spermatozoa is a strategy that has been used to conserve the sperm of animal species and animal strains that are valuable for biomedical research. A simple method for preserving spermatozoa after application of intracytoplasmic sperm injection (ICSI) is much needed. It has been shown previously that spermatozoa frozen at 20°C can activate oocytes and support full-term embryo development. However, epigenetic reprogramming could be affected by the environment and by the in vitro manipulation of gametes. Here, we investigated embryo epigenetic reprogramming including DNA methylation and histone modification, in embryos derived from sperm preserved at 20°C without cryoprotectants. The results showed that although both fertilization and embryo developmental competence were decreased, the dynamic epigenetic reprogramming of embryos derived from frozen sperm was similar to the reprogramming of embryos derived from fresh sperm. The results reported in this study indicate that sperm frozen without cryoprotectant is epigenetically safe for ICSI.
Investigation on high magnetoresistance Ni0.81Fe0.19 films grown on (Ni0.81Fe0.19)1 xCrx underlayers
Haifeng Li,Jidong Ma,Guanghua Yu,Shibin Long,Hongchen Zhao,Fengwu Zhu
Chinese Science Bulletin , 2003, DOI: 10.1007/BF03185757
Abstract: We have fabricated Ni0.81Fe0.19 films with (Ni0.81Fe0.19)1 xCrx films as underlayers by dc magnetron sputtering, the results show that larger anisotropic magnetoresistance (ΔR/R) values of Ni0.81Fe0.19 films are observed using the underlayers with Cr concentration of ~36 at.% at an optimum underlayer thickness of ~4.4 nm, the maximum AMR value is 3.35%. The results of atomic force microscope (AFM) and X-ray diffraction (XRD) show that the ΔR/R enhancement is attributed to the formation of large average grain size and the strong(111) texture in the Ni0.81Fe0.19 films.
A New Gauge for Contact Pressure

MAO Cui,WANG Shibin,TONG Jingwei,LI Hongqi,

实验力学 , 1999,
Abstract: 利用碳材料的压阻效应,研制开发了一种新型的接触压力传感元件碳膜压力传感器,可以直接用它来定量测量两接触体间的接触压力.文中对接触压力传感器的压力电阻(σ-ΔR/R)关系进行了标定,测定了铁基形状记忆合金管接头与被连接管间的接触压力.经与光力学一有限元数值分析混合法结果进行比较后表明;这种新型的碳膜式接触压力传感器性能稳定,操作简便
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