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Search Results: 1 - 10 of 94632 matches for " Shi-Wei Sun "
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Robust optimization for transit timetable design under stochastic demands

SUN Yang,SONG Rui,HE Shi-wei,

系统工程理论与实践 , 2011,
Abstract: 考虑在实际运营中乘客需求具有随机性,固定需求下优化的公交时刻表不适应运营的要求.随机需求下的期望值模型忽略了不利可能事件对运营的负面影响,针对此情况研究随机需求下公交时刻表设计的鲁棒性优化.模型综合考虑乘客成本与运营成本,采用鲁棒性优化权衡目标期望值与偏差期望值.结合随机模拟技术,选用遗传算法求解模型.给出了算例,验证了模型和算法的有效性.通过比较固定需求模型、随机需求期望值模型、随机需求鲁棒性模型,说明在鲁棒性优化下需要提供更多的交通供给以降低偏差期望值.最后,对鲁棒性模型中的偏差权重系数进行了灵敏度分析.
Bis(2-carboxybenzoato-κO1)bis[1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydroquinoline-3-carboxylato-κ2O3,O4]manganese(II) dihydrate
Guang-Ju Zhang,Jiang-Hong He,Shi-Wei Yan,Dian-Zhen Sun
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811011615
Abstract: The title compound, [Mn(C17H18FN3O3)2(C8H5O4)2]·2H2O or [Mn(cfH)2(1,2-Hbdc)2]·2H2O (cfH = ciprofloxacin = 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid, 1,2-bdc = benzene-1,2-dicarboxylate), has been prepared under hydrothermal conditions. The Mn2+ atom, located on an inversion centre, exhibits a distorted octahedral geometry, coordinated by four O atoms from two symmetry-related zwitterionic ciprofloxacin ligands in the equatorial positions and two O atoms of two 1,2-Hbdc ligands in the axial positions. The complex molecules are linked into a two-dimensional network through N—H...O and OW—H...O hydrogen bonds. A strong intramolecular hydrogen bond between the carboxyl/carboxylate groups of the 1,2-Hbdc anion is also present. The layers are further extended through off-set aromatic π–π stacking interactions of cfH groups [centroid–centroid distance of 3.657 (2) ] into the final three-dimensional supramolecular arrays.
Myocardial Scar Identified by Magnetic Resonance Imaging Can Predict Left Ventricular Functional Improvement after Coronary Artery Bypass Grafting
Tao Yang, Min-Jie Lu, Han-Song Sun, Yue Tang, Shi-Wei Pan, Shi-Hua Zhao
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0081991
Abstract: Background Previous studies have shown that viable myocardium predicts recovery of left ventricular (LV) dysfunction after revascularization. Our aim was to evaluate the prognostic value of myocardial scar assessed by late gadolinium-enhanced cardiovascular magnetic resonance imaging (LGE-CMR) on functional recovery in patients undergoing coronary artery bypass grafting (CABG). Methods From November 2009 to September 2012, 63 patients with reduced left ventricular ejection fraction (LVEF) referred for first-time isolated CABG were prospectively enrolled, 52 were included in final analysis. LV functional parameters and scar tissue were assessed by LGE-CMR at baseline and 6 months after surgery. Patency of grafts was evaluated by computed tomography angiography (CTA) 6 months post-CABG. Predictors for global functional recovery were analyzed. Results The baseline LVEF was 32.7±9.2%, which improved to 41.6±11.0% 6 months later and 32/52 patients improved LVEF by ≥5%. Multivariate logistic regression analysis showed that the most significant negative predictor for global functional recovery was the number of scar segments (Odds ratio 2.864, 95% Confidence Interval 1.172–6.996, p = 0.021). Receiver-Operator-Characteristic (ROC) analysis demonstrated that ≤4 scar segments predicted global functional recovery with a sensitivity and specificity of 85.0% and 87.5%, respectively (AUC = 0.91, p<0.001). Comparison of ROC curves also indicated that scar tissue was superior to viable myocardium in predicting cardiac functional recovery (p<0.001). Conclusions Our findings indicated that scar tissue on LGE-CMR is an independent negative predictor of cardiac functional recovery in patients with impaired LV function undergoing CABG. These observations may be helpful for clinicians and cardiovascular surgeons to determine which patients are most likely to benefit from surgical revascularization.
黄海中华哲水蚤 C5 发育期油脂积累初步研究

SUN Song,WANG Shi-Wei,LI Chao-Lun,
孙 松

海洋与湖沼 , 2011,
Abstract: We studied the regional and seasonal changes of the oil storage in the C5 stage of Calanus sinicus in Yellow Sea based on the data collected from 9 cruises. The oil sac of C5s in the nearshore areas was found small all year long. However, C5s from the continental shelf areas were found with great variation in the oil sac volume (OSV). As the dominant stage in the over-summering population, C5 showed maximum OSV between May-June when the population prepared to oversummer. The oil sac volume gradually decreases, and both the nearshore and shelf population showed no significant difference in the OSV by December. The decrease of the oil storage was probably caused by the metabolic consumption. After comparison to the data on Calanus finmarchicus in North Atlantic, we concluded that the oil storage of Calanus sinicus might be the main energy resource during dominant stage. These finding might have significance in understanding its life history in the Yellow Sea.
Study on key frames extraction for video processing in compressed domain

ZHAO Shi-wei,ZHUO Li,SHEN Lan-sun,

计算机应用研究 , 2009,
Abstract: The approach of retrieve key frames from video and then process them is an efficient way to process video data. Reviewed the research results of extracting key frames based on compressed domain in recently years, and made analysis and discussion to retrieve key frames for applications to identify objectionable video. Proposed a fast and efficient scheme for this goal at the end.
Use of Targeted Exome Sequencing in Genetic Diagnosis of Chinese Familial Hypercholesterolemia
Wen-Feng Wu, Li-Yuan Sun, Xiao-Dong Pan, Shi-Wei Yang, Lv-Ya Wang
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0094697
Abstract: Familial hypercholesterolemia is an autosomal dominant inherited disease characterized by elevated plasma low-density lipoprotein cholesterol (LDL-C). It is mainly caused by mutations of the low-density lipoprotein receptor (LDLR) gene. Currently, the methods of whole genome sequencing or whole exome sequencing for screening mutations in familial hypercholesterolemia are not applicable in China due to high cost. We performed targeted exome sequencing of 167 genes implicated in the homozygous phenotype of a proband pedigree to identify candidate mutations, validated them in the family of the proband, studied the functions of the mutant protein, and followed up serum lipid levels after treatment. We discovered that exon 9 c.1268 T>C and exon 8 c.1129 T>G compound heterozygous mutations in the LDLR gene in the proband derived from the mother and father, respectively, in which the mutation of c.1129 T>G has not been reported previously. The mutant LDL-R protein had 57% and 52% binding and internalization functions, respectively, compared with that of the wild type. After 6 months of therapy, the LDL-C level of the proband decreased by more than 50% and the LDL-C of the other family members with heterozygous mutation also reduced to normal. Targeted exome sequencing is an effective method for screening mutation genes in familial hypercholesterolemia. The exon 8 and 9 mutations of the LDLR gene were pedigree mutations. The functions of the mutant LDL-R protein were decreased significantly compared with that of the wild type. Simvastatin plus ezetimibe was proven safe and effective in this preschool-age child.
Effect of oxygen partial pressure and transparent substrates on the structural and optical properties of ZnO thin films and their performance in energy harvesters
Yan-ping Xia,Pei-hong Wang,Shi-wei Shi,Gang He,Miao Zhang,Jian-guo Lü,Zhao-qi Sun
- , 2017, DOI: https://doi.org/10.1007/s12613-017-1450-1
Abstract: Zinc oxide (ZnO) thin films were deposited onto different substrates — tin-doped indium oxide (ITO)/glass, ITO/polyethylene naphthalate (PEN), ITO/polyethylene terephthalate (PET) — by the radio-frequency (RF) magnetron sputtering method. The effect of various O2/(Ar+O2) gas flow ratios (0, 0.1, 0.2, 0.3, 0.4, 0.5, and 0.6) was studied in detail. ZnO layers deposited onto ITO/PEN and ITO/PET substrates exhibited a stronger c-axis preferred orientation along the (0002) direction compared to ZnO deposited onto ITO/glass. The transmittance spectra of ZnO films showed that the maximum transmittances of ZnO films deposited onto ITO/glass, ITO/PEN, and ITO/PET substrates were 89.2%, 65.0%, and 77.8%, respectively. Scanning electron microscopy (SEM) images of the film surfaces indicated that the grain was uniform. The cross-sectional SEM images showed that the ZnO films were columnar structures whose c-axis was perpendicular to the film surface. The test results for a fabricated ZnO thin film based energy harvester showed that its output voltage increased with increasing acceleration of external vibration.
Fabrication of Electrophoretic Particles by Polymer Encapsulation and Characterization of Their Dispersion Stability Using UV Transmittance Method

SUN Shi-wei,REN Jun,MENG Xian-wei,TANG Fang-qiong,

过程工程学报 , 2012,
Abstract: Black pigment nanoparticles were modified with a series of monomers with different polarities by radical grafting polymerization,and the effects of these polymer coating layers on the dispersion stability of copper chromite nanoparticles used in electrophoretic medium were examined by transmittance method.The results show that the stabilization time of particles in nonaqueous medium at least has increased 5 times after polymer modification,and the longer the side chain of monomer,the stabler the particles.When the monomer with an alkyl chain containing more than 4 carbon atoms,the corresponding polymer layers will impart good dispersibility to particles.The final black/white electrophoretic display has a response time of less than 1 s and contrast of(4-5):1 under a bias voltage of 5 V.The present results will provide a guideline for polymer modification of electrophoretic particle and theoretical foundation for improving electrophoretic medium stability and lifetime of electrophoretic display.
Design and Synthesis of Immunoconjugates and Development of an Indirect ELISA for Rapid Detection of 3, 5-Dinitrosalicyclic Acid Hydrazide
Yu-Dong Shen,Shi-Wei Zhang,Hong-Tao Lei,Hong Wang,Zhi-Li Xiao,Yue-Ming Jiang,Yuan-Ming Sun
Molecules , 2008, DOI: 10.3390/molecules13092238
Abstract: In this study novel immunoconjugates were designed, synthesized and then used to develop a rapid, specific and sensitive indirect ELISA method to directly detect residues of 3,5-dinitrosalicyclic acid hydrazide (DNSH), a toxic metabolite of nifursol present in chicken tissues. The hapten DNSHA was first designed and used to covalently couple to BSA to form an immunogen which was immunized to rabbits to produce a polyclonal antibody against DNSH. Furthermore, a novel 3,5-dinitrosalicylic acidovalbumin (DNSA-OVA) immunoconjugate structurally different from DNSHA-OVA was designed and used as a “substructural coating antigen” to improve the sensitivity of an indirect ELISA analysis for a direct DNSH detection. Based on the “substructural coating antigen” concept, an optimized indirect ELISA method was established that exhibited good specificity and high sensitivity for detecting DNSH, with a cross-reactivity of less than 0.1% (excluding the parent compound nifursol), IC50 of 0.217 nmol/mL and detection limit of 0.018 nmol/mL. Finally, a simple and efficient analysis of DNSH samples in chicken tissues showed that the average recovery rate of the indirect ELISA analysis was 82.3%, with the average coefficient of variation 15.9%. Thus, the developed indirect ELISA method exhibited the potential for a rapid detection of DNSH residues in tissue.
An Adaptive Approach to Schema Classification for Data Warehouse Modeling
Hong-Ding Wang,Yun-Hai Tong,Shao-Hua Tan,Shi-Wei Tang,Dong-Qing Yang,Guo-Hui Sun,
Hong-Ding Wang
,Yun-Hai Tong,Shao-Hua Tan,Shi-Wei Tang,Dong-Qing Yang,and Guo-Hui Sun

计算机科学技术学报 , 2007,
Abstract: Data warehouse (DW) modeling is a complicated task, involving both knowledge of business processes and familiarity with operational information systems structure and behavior. Existing DW modeling techniques suffer from the following major drawbacks - data-driven approach requires high levels of expertise and neglects the requirements of end users, while demand-driven approach lacks enterprise-wide vision and is regardless of existing models of underlying operational systems. In order to make up for those shortcomings, a method of classification of schema elements for DW modeling is proposed in this paper. We first put forward the vector space models for subjects and schema elements, then present an adaptive approach with self-tuning theory to construct context vectors of subjects, and finally classify the source schema elements into different subjects of the DW automatically. Benefited from the result of the schema elements classification, designers can model and construct a DW more easily.
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