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Search Results: 1 - 10 of 58961 matches for " Shengping Yang "
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The Virtual Repeat Sale Model for the House Price Index for New Building in China  [PDF]
Weihua Jin, Shengping Jin
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.521320
Abstract: By using the characteristics of the new building in China, this article constructs the virtual repeat sale method to produce virtual repeat data which is similar to the repeat sale model on the house price index. Case-Shiller procedure and OFHEO method are used to calculate the house price index for new building in China. A discussion is given and furthering models are needed to take advantage of the virtual repeat sale data.
Label-Free Proteomics Reveals Decreased Expression of CD18 and AKNA in Peripheral CD4+ T Cells from Patients with Vogt-Koyanagi-Harada Syndrome
Liming Mao,Peizeng Yang,Shengping Hou,Fuzhen Li,Aize Kijlstra
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0014616
Abstract: Vogt-Koyanagi-Harada (VKH) syndrome is a systemic autoimmune disease. CD4+ T cells have been shown to be involved in autoimmune diseases including VKH syndrome. To screen aberrantly expressed membrane proteins in CD4+ T cell from patients with active VKH syndrome, blood samples were taken from five patients with active VKH syndrome and five healthy individuals. A label-free quantitative proteomic strategy was used to identify the differently expressed proteins between the two groups. The results revealed that the expression of 102 peptides was significantly altered (p<0.05) between two groups and matched amino acid sequences of proteins deposited in the international protein index (ipi.HUMAN.v3.36.fasta). The identified peptides corresponded to 64 proteins, in which 30 showed more than a 1.5-fold difference between the two groups. The decreased expression of CD18 and AKNA transcription factor (AKNA), both being three-fold lower than controls in expression identified by the label-free method, was further confirmed in an additional group of five active VKH patients and six normal individuals using the Western blot technique. A significantly decreased expression of CD18 and AKNA suggests a role for both proteins in the pathogenesis of this syndrome.
Preparation and Doping Mode of Doped LiMn2O4 for Li-Ion Batteries
Qiuling Liu,Shengping Wang,Haibo Tan,Zhigao Yang,Jian Zeng
Energies , 2013, DOI: 10.3390/en6031718
Abstract: Spinel LiMn 2O 4 is an appealing candidate cathode material for Li-ion rechargeable batteries, but it suffers from severe capacity fading, especially at higher temperature (55 °C) during discharging/charging. In recent years, many attempts have been made to synthesize modified LiMn 2O 4. This paper reviews the recent research on the preparation and doping modes of doped LiMn 2O 4 for modifying the LiMn 2O 4 . We firstly compared preparation methods for doped spinel LiMn 2O 4, such as solid state reactions and solution synthetic methods. Then we mainly discuss doping modes reported in recent years, such as bulk doping, surface doping and combined doping. A comparison of different doping modes is also provided. The research shows that the multiple-ion doping and combined doping modes of LiMn 2O 4 used in Li-ion battery are excellent for improving different aspects of the electrochemical performance which holds great promise in the future. From this paper, we also can see that spinel LiMnO 4 as an attractive candidate cathode material for Li-ion batteries.
Acetylene Black/Sulfur Composites Synthesized by a Solution Evaporation Concentration Crystallization Method and Their Electrochemical Properties for Li/S Batteries
Haibo Tan,Shengping Wang,Du Tao,Zhigao Yang
Energies , 2013, DOI: 10.3390/en6073466
Abstract: A novel technique to prepare carbon/sulfur composites as cathode materials for Li/S batteries is proposed, which we call the ‘solution evaporation concentration crystallization’ method. Three composites with different S loadings were prepared, subject to two different solvent evaporation rates from acetylene black (AB)/sulfur in carbon disulfide solutions. X-ray diffraction, environmental scanning electron microscopy, transmission electron microscopy, and Brunauer-Emmett-Teller measurements all show that the porous AB structure is well-filled with S. Composites prepared at a lower solvent evaporation rate with 50 wt % S content, had good electrochemical properties, with 1609.67 mAh g ?1 after 100 cycles. Composites with better dispersibility at a low solvent evaporation rate can effectively prevent polysulfide from dissolving in the electrolyte, and serve to stabilize the structure of the S cathode during the charge-discharge process.
Risk of Bias Tool in Systematic Reviews/Meta-Analyses of Acupuncture in Chinese Journals
Yali Liu,Shengping Yang,Junjie Dai,Yongteng Xu,Rui Zhang,Huaili Jiang,Xianxia Yan,Kehu Yang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0028130
Abstract: Use of a risk of bias (ROB) tool has been encouraged and advocated to reviewers writing systematic reviews (SRs) and meta-analyses (MAs). Selective outcome reporting and other sources of bias are included in the Cochrane ROB tool. It is important to know how this specific tool for assessing ROB has been applied since its release. Our objectives were to evaluate whether and to what extent the new Cochrane ROB tool has been used in Chinese journal papers of acupuncture.
Reduction of the East Asian winter monsoon interannual variability after the mid-1980s and possible cause
ShengPing He
Chinese Science Bulletin , 2013, DOI: 10.1007/s11434-012-5468-5
Abstract: The East Asian winter monsoon (EAWM) consists of subsystems such as the Siberian high, Aleutian low, East Asian trough, low-level northerly wind and high-level East Asian jet stream. It is revealed that the interannual variation of the EAWM-related atmospheric circulation has exhibited an obvious weakening since the mid-1980s. During 1956–1980, significant negative correlations between the EAWM and sea surface temperature are observed in the oceans along the east coast of East Asia, accompanied by significant positive correlations in the western Warm Pool. However, the significant interannual relationship in the previous period is found to have been disrupted during 1986–2010. Further analysis reveals that the Arctic Oscillation after the mid-1980s tends to suppress the interannual variability of the EAWM. In addition, it was found that the large-scale warming after the mid-1980s is favorable to reduce the land-sea thermal contrast variability on both the interdecadal and interannual time scales.
No Association of PTPN22 Polymorphisms with Susceptibility to Ocular Behcet's Disease in Two Chinese Han Populations
Qi Zhang, Shengping Hou, Zhengxuan Jiang, Liping Du, Fuzhen Li, Xiang Xiao, Aize Kijlstra, Peizeng Yang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031230
Abstract: Background Behcet's disease is known as a recurrent, multisystem inflammation and immune-related disease. Protein tyrosine phosphatase non-receptor 22 (PTPN22) is a key negative regulator of T lymphocytes and polymorphisms of the PTPN22 gene have been shown to be associated with various immune-related diseases. The present study was performed to assess the association between PTPN22 polymorphisms and Behcet's disease in two Chinese Han populations. Methodology/Principal Findings A total of 516 patients with ocular Behcet's disease and 690 healthy controls from two Chinese Han populations were genotyped by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method for three single nucleotide polymorphisms (SNPs). Hardy-Weinberg equilibrium was tested using the χ2 test. Genotype frequencies were estimated through direct counting. Allele and genotype frequencies were compared between patients and controls using logistic regression analysis. The results revealed that there was no association between the tested three PTPN22 SNPs (rs2488457, rs1310182 and rs3789604) and ocular Behcet's disease (p>0.05). Categorization analysis according to the clinical features did not show any association of these three polymorphisms with these parameters (p>0.05). Conclusions/Significance The investigated PTPN22 gene polymorphisms (rs2488457, rs1310182 and rs3789604) were not associated with ocular Behcet's disease in two Chinese Han populations, and showed that it may be different from other classical autoimmune diseases. More studies are needed to confirm these findings for Behcet's disease in other ethnic backgrounds.
Lack of an Association of PD-1 and Its Ligand Genes with Behcet's Disease in a Chinese Han Population
Qianli Meng, Haike Guo, Shengping Hou, Zhengxuan Jiang, Aize Kijlstra, Peizeng Yang
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0025345
Abstract: Background Behcet's disease is a chronic, multi-systemic autoimmune disease. Programmed cell death 1 (PD-1) gene is one of non-human leucocyte antigen genes. It has been demonstrated to be associated with several autoimmune diseases. However, only a few studies have addressed the association of ligand genes of PD-1, PD-L1 and PD-L2 with autoimmune disease. The purpose of this study was to analyze the potential association of the PD-1 and its ligand genes with Behcet's disease in a Chinese Han population. Methodology/Principal Findings Four single-nucleotide polymorphism (SNPs) rs2227981 and rs10204525 of PD-1, rs1970000 of PD-L1 and rs7854303 of PD-L2 were genotyped in 405 Behcet's patients and 414 age-, sex-, ethnic-matched healthy controls using polymerase chain reaction-restriction fragment length polymorphism assay. The results revealed that there were no significant differences in the genotype and allele frequencies of PD-1 rs2227981 and rs10204525 between the Behcet's patients and controls. A similar result was found for PD-L1 rs1970000 versus healthy controls. Only the C allele and the CC genotype of PD-L2 rs7854303 were identified in patients and controls. Stratification analysis based on gender and clinical findings did not show any associations between PD-1 or its ligand polymorphisms and Behcet's disease. Conclusions/Significance None of the currently studied SNPs, PD-1 rs2227981 and rs10204525, PD-L1 rs1970000 and PD-L2 rs7854303, are associated with the susceptibility to Behcet's disease in a Chinese Han population. More studies are needed to confirm these findings in Behcet's patients with other ethnic backgrounds.
Replication study confirms the association between UBAC2 and Beh?et's disease in two independent Chinese sets of patients and controls
Shengping Hou, Qinmeng Shu, Zhengxuan Jiang, Yuanyuan Chen, Fuzhen Li, Feilan Chen, Aize Kijlstra, Peizeng Yang
Arthritis Research & Therapy , 2012, DOI: 10.1186/ar3789
Abstract: The genotyping of five candidate genes/loci, including LOC100129342, KIAA1529, CPVL, UBASH3B and UBAC2, were performed using TaqMan single nucleotide polymorphism (SNP) assays. Real-time PCR and luciferase reporter assay were performed to test the function of the identified promoter polymorphism. The main outcome measures were genotype frequencies and expression levels in BD patients.The first-stage study results showed that UBAC2 (rs9513584, Pc = 0.018, OR = 1.4), but not LOC100129342, KIAA1529, CPVL, UBASH3B was associated with the susceptibility to BD in Chinese Han. The fine-mapping association study of UBAC2 identified six risk SNPs for BD in the Chinese cohort; three of them were verified in validation study (rs3825427, first-stage Pc = 2.2 × 10-3, second-stage Pc = 9.3 × 10-3, combined Pc = 6.9 × 10-6; rs9517668, first-stage Pc = 1.7 × 10-3, second-stage Pc = 0.03, combined Pc = 3.3 × 10-4; rs9517701, first-stage Pc = 5.1 × 10-3, second-stage Pc = 9.0 × 10-3, combined Pc = 2.9 × 10-5; respectively). Functional analysis showed that the risk T allele of the promoter polymorphism rs3825427 had a significantly lower promoter activity than the non-risk G allele (P = 0.002) and a decreased expression of UBAC2 transcript variant 1 in peripheral blood mononuclear cells (PBMCs) and skin of normal controls carrying the risk T allele than that in individuals with the G allele (P = 0.045, P = 0.025; respectively). The mRNA expression of UBAC2 transcript variant 1 was significantly decreased in PBMCs and skin of BD patients as compared with controls (P = 0.025; P = 0.047, respectively). The mRNA expression of UBAC2 transcript variant 2 was significantly increased in skin of BD patients as compared with controls (P = 0.004).This study replicates a predisposition gene to BD, UBAC2, and suggests that UBAC2 may be involved in the development of BD through its transcriptional modulation.Beh?et's disease (BD) is generally considered as a refractory multisystem disorder characte
FGFR1OP tagSNP but Not CCR6 Polymorphisms Are Associated with Vogt-Koyanagi-Harada Syndrome in Chinese Han
Xianglong Yi, Liping Du, Shengping Hou, Fuzhen Li, Yuanyuan Chen, Aize Kijlstra, Peizeng Yang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069358
Abstract: Background Polymorphisms of the CC chemokine receptor 6 (CCR6) and FGFR10P tagSNP (locus close to CCR6) at 6q27 have recently been reported to be associated with the susceptibility to several immune-related diseases. This study was designed to determine the association of CCR6 and FGFR10P (tag)SNPs with Vogt-Koyanagi-Harada (VKH) syndrome, an autoimmune disease directed against melanocytes, in two independent Chinese Han populations. Methodology/Principal Findings A total of 601 VKH patients and 725 healthy controls from two Chinese Han populations were genotyped by the polymerase chain reaction-restriction fragment length polymorphism method. Hardy-Weinberg equilibrium was tested using the χ2 test. Genotype frequencies were estimated by direct counting. Allele and genotype frequencies were compared between patients and controls using the χ2 test. The frequency of the A allele of rs2301436 was significantly higher both in Cohort 1 and Cohort 2 as compared with two separate controls (P = 0.044; P = 0.049, respectively). The significance was lost after Bonferroni correction in both cohorts (Pc = 0.516; Pc = 0.392, respectively). The frequency of the A allele was significantly higher in the combined patient group as compared with all controls before and after Bonferroni correction (P = 0.005, Pc = 0.025). The genotype and allele frequencies of rs3093024, rs6902119, rs3093023 and rs968334 were not different between patients with VKH and healthy controls based on analysis either for both cohorts or for the patients and controls in total. Analysis according to extra ocular clinical findings including headache, alopecia and poliosis, vitiligo and tinnitus did not show any association of the five polymorphisms with these parameters. Conclusion These results suggest that the rs2301436 tagSNP of FGFR10P is positively associated with susceptibility to VKH syndrome in the tested Chinese Han populations. No association was found for the tested CCR6 SNPs.
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