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Search Results: 1 - 10 of 8149 matches for " Sharma Sudarshan "
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Acquired vulval lymphangiectases mimicking genital warts
Sharma Rajeev,Tomar Sudarshan,Chandra Mithilesh
Indian Journal of Dermatology, Venereology and Leprology , 2002,
Abstract: Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.
Papillary cystadenocarcinoma of submandibular salivary gland: A rare case report
Mardi Kavita,Sharma Sudarshan,Gupta Neelam
Journal of Cancer Research and Therapeutics , 2010,
Abstract: Papillary cystadenocarcinoma is an extremely rare malignant neoplasm characterized by cysts and papillary endophytic projections. It was first defined in 1991 by World Health organization as a separate entity. Major locations of this neoplasm are the parotid gland, the sublingual gland, and minor salivary glands, while occurrence in the submandibular gland is extremely rare. We present a case of papillary cystadenocarinoma arising from the submandibular gland in a 67-year-old male patient. Further, we have discussed the cytological and histopathological features of this rare entity and reviewed the current literature.
Cytomorphological features of Hürthle cell carcinoma: A report of two cases with review of literature
Mardi Kavita,Gupta Neelam,Sharma Sudarshan,Negi Lalita
Journal of Cytology , 2010,
Abstract: The use of the term "Hürthle cell neoplasm" as the gold standard should be discouraged as it makes evaluating these lesions more confusing. Recently, a number of studies have been conducted to define criteria that are more specific for Hürthle cell carcinoma (HCC). We herein report two cases of HCC of thyroid which were accurately diagnosed preoperatively using various cytological features described in the recent studies. A review of the literature is also presented.
Visual outcome after intravenous dexamethasone therapy for idiopathic optic neuritis in an Indian population: A clinical case series
Sethi Harinder,Menon Vimla,Sharma Pradeep,Khokhar Sudarshan
Indian Journal of Ophthalmology , 2006,
Abstract: Purpose: To evaluate the clinical profile, response to dexamethasone treatment and visual function outcome in Indian patients with acute optic neuritis. Materials and Methods: We conducted an observational study of patients with acute optic neuritis who were treated with intravenous dexamethasone (100 mg in 250 ml of 5% dextrose over 1-2 hours daily, for three consecutive days) and had completed at least two years of follow-up. Parameters assessed included visual acuity, contrast sensitivity, color vision, visual fields, relative afferent pupillary defect (RAPD) and visually evoked potentials. Out of 40 patients studied, 26 patients (33 eyes) had all visual function parameters assessed. Twenty three patients (28 eyes) had completed two years of follow-up and were included for statistical analysis. Results: Improvement in visual acuity was statistically significant for distance after 24 hours of the first dose ( P = < 0.001) and for near vision after 24 hours of the second dose ( P = 0.006); improvement in color and contrast sensitivity was statistically significant 24 hours after the third dose ( P = < 0.001 for color vision and P = 0.013 for contrast sensitivity). Significant improvement in RAPD and visual fields were seen by 1 month ( P = 0.005). Recurrence was seen in 4 eyes of 4 patients. No serious side effects were observed. At two years, 82.14% (23 out of 28) eyes had visual acuity > 20/40. Conclusion: Treatment with intravenous pulsed dexamethasone led to rapid recovery of vision in acute optic neuritis, without any serious side effects.
Phylogenetics and Srf Analysis of Mitochondrial DNA COII Gene in Anopheles Species (Diptera: Culicidae)
Monika Sharma,Taruna Kaurab,Rashmi Kohlia,Sudarshan Chaudhry
Journal of Scientific Review , 2011,
Abstract:
Sorption and desorption behavior of lead in four different soils of India  [PDF]
Sudarshan K. Dutta, Dhanwinder Singh
Agricultural Sciences (AS) , 2011, DOI: 10.4236/as.2011.21007
Abstract: Sorption and desorption mechanisms of lead (Pb) were determined in four different soils collected from different agro-climatic regions of India. The soils were classified as: fine loamy mixed Typic- Dystrudepts, fine sandy loam Typic Ustochrepts, fine loamy Typic Ustochrept, and fine sandy loam Udic Haplustalfs. Seven different Pb solutions [Pb(NO3)2 dissolved in 0.01M Ca(NO3)2] in a range of 400 to 2000µgL-1 were applied to study the sorption amounts at 25(±2)oC and 45(±2)oC temperatures. With the increase in application rate and tempera-ture, sorption amounts of Pb increased; however, percentages of sorption of applied Pb were decreased. Sorptions were positively and significantly (p≤0.01) correlated with Langmuir adsorption isotherm. Thermodynamic parameters of sorption (i.e. Ko, ?Go, ?Ho, and ?So) were also determined at two tempera-tures, 25(±2)oC and 45(±2)oC. Increase in Ko with the increase in temperature indicated positive effect of temperature on Pb sorption. High absolute values of ?Go, and positive values of ?Ho, and ?So suggested that the sorption reaction was spontaneous and en-dothermic. Sorbed Pb were desorbed in Pb free 0.01M Ca(NO3)2 solutions at 25(±2)oC and 45(±2)oC. Desorption amounts increased with increase in the Pb application rate, but not always with the increase in temperature.
Cervical Disc Replacement: A Systematic Review of Medline Indexed Literature  [PDF]
Sudarshan Munigangaiah, John P. McCabe
International Journal of Clinical Medicine (IJCM) , 2013, DOI: 10.4236/ijcm.2013.47A1006
Abstract: Anterior Cervical Discectomy and Fusion (ACDF) currently remains as the gold standard treatment for cervical disc herniation and Degenerative Disc Disease (DDD) refractory to conservative management. Even though anterior cervical fusion provides excellent clinical results, it has been implicated in abnormal kinematic strain on adjacent disc level resulting in symptomatic adjacent segment disease. Anterior cervical disc replacement (ACDR) is an alternative procedure to anterior cervical discectomy and fusion. The aims of cervical disc replacement were to preserve the motion at the index level and to protect the adjacent levels from accelerated symptomatic degeneration. The aim of this systematic review was to evaluate the outcomes of cervical disc replacement published in MEDLINE indexed literature. A literature search was carried out in medical electronic database MEDLINE. Keywords used for the search were Cervical vertebrae, Cervical spine, Neck, Intervertebral disc, Total disc replacement, Arthroplasty, Replacement, Treatment outcome. Two authors reviewed titles and abstracts of all two hundred and thirty six hits. The articles that satisfied the inclusion criteria were critically appraised while remaining articles were discarded. Anterior cervical disc replacement is a relatively new technology in spinal surgery. There are several short and intermediate term follow-up studies to prove the safety and efficacy of ACDR with satisfactory clinical and radiological outcomes. More intermediate to long-term follow-up studies are needed to prove the safety and efficacy of ACDR.
Study on Empathy among Undergraduate Students of the Medical Profession in Nepal  [PDF]
Krishna Bahadur GC, Sudarshan Paudel
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.511007
Abstract: Background: The incumbent of medical professional is expected to be socially responsible and emotionally empathetic along with good communication propensity to fasten the doctor-patient relationship. Whilst doctor’s proficiency to recognize a patient’s perspectives, and convey such an understanding back to the patient; in our case, the empathy and compassion level of promising medical professional is unknown in Nepal. Thus, this study aimed to analyze the compassion and empathy score of final year’s undergraduate students of four medical colleges in Nepal. Methods: Self-reported empathy measures were obtained using the Jefferson Scale of Physician-Student version. Results: The degree of empathy for the participants was 97.28 (SD = 14.44) with a median score of 96.00 and a range of 44 (min) to 133 (max). There was a significant difference on scores of the Jefferson scale of physician empathy between NMC Nepalgunj and BPKIHS (p = 0.00) and between NMC Nepalgunj and Manipal Pokhara (p = 0.00), as well as between UCMS and Manipal Pokhara (p = 0.044). These results were significant at the 95% confidence interval. Conclusions: The mean empathy score for the Nepali students is lower than medical students from developed countries but almost similar to medical students from other Asian medical students. The female Nepali medical students scored slightly higher than their male counterparts. Thus colleges have to develop academic programs to improve empathy and compassion among medical students through providing adequate time to consult with patient and faculties.
Assessing Burden of Rabies in India : WHO Sponsored National Multicentric Rabies Survey, 2003
Sudarshan M
Indian Journal of Community Medicine , 2005,
Abstract:
A brief primer on microRNAs and their roles in angiogenesis
Anand Sudarshan
Vascular Cell , 2013, DOI: 10.1186/2045-824x-5-2
Abstract: Development of the vasculature is a complex, dynamic process orchestrated by a balance of pro and anti-angiogenic signaling pathways. The same signaling pathways are mis-regulated and exploited during pathological angiogenesis in cancer, inflammation and cardiovascular diseases and contribute to disease progression. In the last decade, small non-coding RNA molecules termed microRNAs (miRs) have emerged as key regulators of several cellular processes including angiogenesis. It is becoming clear that miRs function in complex networks and regulate gene expression both at the mRNA and protein levels thereby altering cellular signaling responses to specific stimuli. In the vasculature, miRs can function either in a pro-angiogenic manner and potentiate angiogenesis or act as anti-angiogenic miRs by enhancing cell death and decreasing endothelial proliferation. This review aims to provide an update on how microRNAs regulate gene expression and illustrate miR function in the vasculature with a discussion of potential applications of miRs as anti-angiogenic therapeutics.
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