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"SERUM FERRITIN IN TYPE 2 DIABETES MELLITUS AND ITS RELATIONSHIP WITH HbA1c"
F. Sharifi Sh. Sazandeh
Acta Medica Iranica , 2004,
Abstract: Diabetes mellitus (DM) type 2 is one of the most common endocrine disorders affecting more than 135 million people in the world. The etiology of the disease is not fully understood, but recently subclinical hemochromatosis has been considered as one of the probable causes of DM. This study was carried out to examine the relationship between serum ferritin as a marker of iron overload with DM and HbA1c. This study was conducted on 97 patients with type 2 DM who were referred to Zanjan Diabetes Clinic. Ninety-four normal age-matched individuals were included in the study as the control group. Ferritin, hemoglobin, HbA1c, and fasting blood sugar were measured in blood samples. Exclusion criteria included anemia, or any other disease or drug that could affect ferritin levels. Results were analyzed statistically by Chi-square test, t-test and Pearson regression coefficient test. One hundred ninety-one cases including 97 diabetics (37 males and 60 females) and 94 normal individuals were studied. There were no significant differences between the two groups regarding age, hemoglobin and body mass index. Mean serum ferritin was significantly higher in diabetics than in the control group (101±73 mg/ml vs. 43.5+42 mg/ml, p<0.001). There was no correlation between serum ferritin and HbA1c in diabetic patients of either sex. Ferritin levels in patients with DM is high, but not related to levels of HbA1c and blood glucose control.
"A Modified Method for Preparation of Staphylococcus aureus Peptidoglycan Towards Making a Sub – Unit Vaccine"
F Esmaily,MK Sharifi–Yazdi
Iranian Journal of Public Health , 2002,
Abstract: The immounological responses to S. aureus cell wall antigens, namely crude or whole cell, teichoic acid (TA) peptidoglycan prepared in conventional way (CPG), cell wall (CW), lipoteichoic acid (LTA) were investigated by number of immunological methods e.g. RIA, ELISA, immunodiffusion and western blotting techniques.Also a method for preparation of peptidoglycan (MPG) was modified and used as vaccine for our protection studies. In general the responses in rabbits (serum titre) to fractions of S. aureus, varied, crued antigen showed the highest end-point titer while lipoteichoic acid showed the lowest end-point. The highest end-point titre was always seen between homologous sera and antigens. Modified pepdidoglycan and cell wall (PG + TA) showed the similar titre against S. epidermidis hyperimmueserum. The cross – reactivty was also seen between fractions by S. aureus Bate . S. aureus Wood (lack protein A) S. epidermidis and streptococci against various immune sera tested by Elisa and gel diffiusion. The results demonstrated that protective antibody can be obtained between different strain or species of bacteria due to the presence of common antigen or antigenes especially PG in gram - positive bacteria.
Spatial Distribution and Molecular Identification of Leishmania Species from Endemic Foci of South-Eastern Iran
F Sharifi,I Sharifi,M Zarean,M Hakimi Parizi
Iranian Journal of Parasitology , 2012,
Abstract: Background: Cutaneous leishmaniasis constitutes a major public health problem in many parts of the world including Iran. The primary objective of this study was to identify Leishmania species in endemic districts of Kerman Province, south-eastern Iran. Methods: This study was conducted by random sampling as cross- sectional descriptive between 2008 and 2010. Overall, 203 skin scraping smears were taken from the patients. Nested -PCR was performed to amplify variable minicircle fragments of Leishmania kDNA.Results: Bam was the most infected district (71.1%), followed by Kerman (14.7%), Jiroft (5.4%), Baft (2.7%), Sirjan (1.6%), Shahr-e Babak (1.5%) and others (3.0%).& L. tropica was the most common species identified (194 cases, 95.6%), while L. major was found in only 9 cases (4.4%). Of 203 identified patients, all species in Bam (l07 cases), Kerman (32 cases), Jiroft (l6 cases) and Shahr-e- Babak (l1 cases) were detected as L. tropica, whereas infected subjects in Baft and Sirjan showed L. tropica or L. major. Characterization of Leishmania species resulted in generation of 750 bp and 560 bp fragments, corresponding to those of L. tropica and L. major, respectively.Conclusion: L. tropica is the main species (95.6%) caused ACL in endemic areas of Kerman Province; however L. major is present in low level (4.4%).
Activation Volume of Secondary Relaxation  [PDF]
Soheil Sharifi
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.26084
Abstract: Glass forming materials are characterized by a complex relaxation pattern, which evolves over several time decades. Dielectric spectroscopy has proven particularly useful for studying such scenario as it is able to monitor the dielectric dynamics of a system over a range up to 16 time decades. In this work we study effect of thermodynamic history on activation volume of secondary relaxation inside the glassy forming systems, Poly[(phenyl glycidyl ether)-co-formaldehyde], (PPGE) and 1,18-bis (p methoxyphenyl) cyclohexane (BMPC), with two different type of secondary relaxation. Our results show that at bout systems, activation volume of secondary depends to the thermodynamic history.
Dielectric spectroscopy of diglycidyl ether of bisphenol-A at glass transition temperature  [PDF]
Soheil Sharifi
Natural Science (NS) , 2012, DOI: 10.4236/ns.2012.42020
Abstract: We used broadband dielectric spectroscopy in the frequency range from 10–2 Hz up to 107 Hz and we found dynamics of the primary α- and intermolecular Johari-Goldstein (JG) β-processes are strongly correlated in diglycidyl ether of bisphenol-A over a wide temperature from 193 to 283K and pressure P range from 0.1 to 600 MPa. Analysing the temperature and pressure behavior of the α - and (JG) β-processes, a clear correlation has been found between the structural relaxation time, the Johari-Goldstein relaxation time and the dispersion of the structural relaxation. These results support the idea that the Johari-Goldstein relaxation acts as a precursor of the structural relaxation and therefore of the glass transition phenomenon.
Dielectric Spectroscopy of PVAc at Different Isobaric-Isothermal Paths  [PDF]
Soheil Sharifi
Materials Sciences and Applications (MSA) , 2012, DOI: 10.4236/msa.2012.33026
Abstract: We studied broadband dielectric spectroscopy of a glass from systems that the dynamics of the primary α- and the Johari-Goldstein (JG) β-processes are strongly correlated in Poly(vinyl acetate) over a wide temperature T and pressure P range. Analysing the temperature and pressure behaviour of the α- and (Non-JG) β-processes, a correlation hasnot been found between the structural relaxation time, the (Non-JG) β-processes relaxation time and the dispersion of the structural relaxation. These results support the idea that the (JG)-processes relaxation acts as a precursor of the structural relaxation and therefore of the glass transition phenomenon but it isnot clear relation in the (Non-JG) β-processes and structural relaxation at PVAc.
"Laboratory Evaluation of Urine Culture and Drug Resistance in Childern Clinically Suspected of Urinary Tract Infection (UTI)"
F Vaezzadeh,MK Sharifi-Yazdi
Iranian Journal of Public Health , 2001,
Abstract: Urine specimens from 6656 children clinically suspected of urinary tract infection were evaluated bacteriologically. Bacterial colony count of over (103) colony forning units CFU/ ml were found in 480 (7.2%) of total cases, with 342 (71.25%) girls and 138 (28.75%) boys. Bacterial etiology of positive culture were determind. Escherichia coli was the most frequent etiologic agent (75.62%) followed by klebsiella species (7.32%). The antimicrobial resistance behaviour of Escherichia coli to routinely used antibiotics were tested. Most strains of Escherichia coli were resistant to cotrimoxazole (82%) and ampicillin (82%), but none of them were resistant to ceftizoxime. Correlation between positive urine culture and pyuria for the diagnosis of UTI was compared. It was noted that approximately 38% of paitents with positive urine culture did not have pyuria.
Oral Fluid Therapy in Severe Diarrheal Dehydration
SJ Sharifi,F Ghavami,Z Nowroozi
Iranian Journal of Pediatrics , 1986,
Abstract: 1330 children, birth to 24 months old, suffering from diarrhea and moderate to severe dehydration were hospitalized in Tehran university hospital over a period of 11 months. 15% of them had signs of shock, and 305 had marasmus. On admission, plasma sodium ranged from 106 to 144 mmol/l, potassium 1.4 to 7.7 mmol/l, bicarbonate 2 to 24 mmol/l, chloride 83 to 161 mmol/l and PH ranged from 6.48 to 7.56. All patients were treated orally in two phases: A) Rehydration therapy, and B) Maintenance therapy. For rehydration, electrolyte solution A (EA: Sodium 80, potassium 20 mmol/l) was administrated at a rate of 40 ml/kg/h until all signs of dehydration disappeared. Following complete dehydration, the patients were discharged and maintenance therapy was performed at home, by mothers, administrating electrolyte solution B (EB: Sodium 40, potassium 30 mmol/l) ad libitum. Antibiotics, anti-diarrhea and anti-emetic drugs were not used. Intravenous fluids were not used either, even in sever dehydration. The efficacy and safety of this regimen were confirmed by rapid and successful rehydration and correction of the electrolyte abnormalities present on admission. The study indicates that this protocol could be successfully employed in all types and severities of dehydration electrolyte abnormalities. It could be used in both well-nourished and in those with severe marasmus. It could also replace intravenous fluid in the majority of such patients.
Oral Fluid Therapy in Iran
SJ Sharifi,F Ghavami,Z Nowroozi
Iranian Journal of Pediatrics , 1985,
Abstract: In 1950, 520 newborn to adult patients with diarrhea and vomiting were hospitalized in Tehran and some of the southern cities of Iran. The patients were different in: States of nutrition, severity of fluid deficits and a wide range of electrolyte abnormalities. They were treated in two separate phases using 2 different solutions, which are formulated upon physiobiochemical principles being iso-osmatic with plasma. For deficit therapy solution no. 1 (Sodium 80, potassium 20 mmol/l) was administrated orally at a rate of 40 ml/kg. Per hour until all signs of dehydration disappeared. (This is maintenance therapy the second solution (Potassium 30, sodium 40 mmol/l, i.e. K:Na in normal=75%) was given sip by sip at a rate of 250 ml/kg/24 hours until diarrhea stopped. Intravenous fluids were not used at all even in severe dehydration and shock. The efficacy and safety of this regimen were confirmed by rapid and successful dehydration and correction of a wide range of electrolyte abnormalities present on admission.
Automatic astronomical coordinate determination using digital zenith cameras
S Farzaneh,MA Sharifi,F Samadzadegan
Iranian Journal of Physics Research , 2009,
Abstract: Celestial positioning has been used for navigation purposes for many years. Stars as the extra-terrestrial benchmarks provide unique opportunity in absolute point positioning. However, astronomical field data acquisition and data processing of the collected data is very time-consuming. The advent of the Global Positioning System (GPS) nearly made the celestial positioning system obsolete. The new satellite-based positioning system has been very popular since it is very efficient and convenient for many daily life applications. Nevertheless, the celestial positioning method is never replaced by satellite-based positioning in absolute point positioning sense. The invention of electro-optical devices at the beginning of the 21st century was really a rebirth in geodetic astronomy. Today, the digital cameras with relatively high geometric and radiometric accuracy has opened a new insight in satellite attitude determination and the study of the Earth's surface geometry and physics of its interior, i.e., computation of astronomical coordinates and the vertical deflection components. This method or the so-called astrogeodetic vision-based method help us to determine astronomical coordinates with an accuracy better than 0.1 arc second. The theoretical background, an innovative transformation approach and the preliminary numerical results are addressed in this paper.
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