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Search Results: 1 - 10 of 9618 matches for " Sharief Ahmed Wani "
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Open management of neglected inferior dislocation of the shoulder with proximal humeral fracture in an adolescent
Shabir Ahmed Dhar,Sharief Ahmed Wani,Tahir Ahmed Dar,Shahid Hussain,Reyaz Ahmed Dar,Abdul Rouf Malik
Strategies in Trauma and Limb Reconstruction , 2013, DOI: 10.1007/s11751-012-0151-6
Abstract: Neglected dislocation of the shoulder is a rare condition with some cases of anterior and posterior dislocation being reported. We report a case with a fracture dislocation of the proximal humerus with the dislocated head lying inferior to the glenoid. We also report on the surgical management of a case with this extremely rare condition which required shortening of the distal fragment to reduce tissue tension.
Evaluating the Importance of Apoptotic Index, Mitotic Index and Turnover Index in Premalignant and Malignant Lesions of Cervix  [PDF]
Subhash Bhardwaj, Farooq Ahmed Wani
Open Journal of Pathology (OJPathology) , 2015, DOI: 10.4236/ojpathology.2015.52005
Abstract: Aim: To evaluate the premalignant and malignant lesions of the uterine cervix on light microscopy for apoptosis. To calculate and correlate the apoptotic index (AI), mitotic index (MI) and turnover index of the lesions. Materials and methods: A 2-year retrospective (November 2007 to October 2009) and 1-year prospective study (November 2009 to October 2010). A total of 95 cases of premalignant and malignant lesions of cervix were studied. The hematoxylin-eosin stained slides were screened for apoptosis under oil immersion lens. Apoptotic index (AI) was calculated as the number of Apoptotic cells and Apoptotic bodies, expressed as percentage of total no. of tumour cells counted in each case. Mitotic index (MI) was calculated by counting mitosis among 1000 tumour cells. Turnover index (TOI) was obtained by adding MI and AI, i.e., (TOI = MI + AI). After calculating, all these indices were correlated with different grades of the cervical lesions. Results: Premalignant lesions were divided into four subgroups. On statistical analysis, it was found that the difference in the apoptotic indices and turnover indices in all the four subgroups was not statistically significant. However for mitotic indices, significant statistical difference was found in Subgroup II (mild dysplasia vs. moderate dysplasia) with a p value of 0.03 and in subgroup IV (squamous metaplasia vs. moderate/severe dysplasia) with a p value of 0.0005. Within the malignant group, we compared well differentiated with less well differentiated subgroup. Statistical analysis revealed a significant difference in TOI between the two subgroups of malignant tumours (p = 0.04). Statistical comparison between premalignant and malignant group of lesions showed a highly significant difference between the AI, MI and TOI with p value of 0.0001. Conclusion: We conclude that proliferative and apoptotic indices are useful in distinguishing between benign and malignant lesions of the cervix. Proliferative activity of a lesion is a reliable indicator of its malignant potential and together with apoptotic count gives an idea about the net growth of a tumour.
Clinical Profile of HIV/Aids Patients in Srinagar, Kashmir, India
Kaiser Ahmed Wani
International Journal of Collaborative Research on Internal Medicine & Public Health , 2012,
Abstract: Background: Since the inception of the integrated counseling and testing centre (ICTC) at government medical college (GMC) and associated hospitals, there was no previous study on the clinical experiences in HIV/Aids positive cases in this institution.Objectives: The aim of this study was to delineate the epidemiological profile of HIV/Aids seropositive cases and which included to study: Number of HIV seropositive patients from april 2002 to december 2009. Common signs and symptoms of HIV/Aids seropositive patients. Age and sex distribution of all seropositive cases. Mode of transmission of HIV infection. Residence and profession profile of seropositive cases. Different types of opportunistic infections in these patients. Study design: The present study is documental and analytical descriptive and it was conducted at the government medical college and associated hospitals through data collection of 128 records of individual who tested positive for HIV by three rapid test methods using three different antigens at integrated counseling and testing centre (ICTC). Demographic variables such as age, sex and occupation, data on mode of transmission and clinical manifestation were examined together.Results: A total of 128 patients had tested positive for HIV by at least three tests using three different antigens, which included 112(87.5%) male and 16(12.5%) females. The mean age of these patients were 34.45±8.40 with male to female ratio of 7:1.The peak incidence was found in the age group of 30-39yrs (36.8%). Majority of HIV positive patients belonged to security personnel’s followed by migrant labourers and housewives. Transmission of infection was through sexual contact in 90.7 % followed by homosexual transmission in 4.7 %. Vertical transmission and blood transfusion accounted in 2.3% cases each. 78.9 % of patients presented with fever of > 1 month duration, 35.1 % with weight loss and 33.5% with diarrhea. Tuberculosis and candidiasis were common opportunistic infection followed herpes zoster and varicella. Conclusion: This study highlights the burden of HIV/Aids patients in the study place. The results will be useful for various programmes in health promotions in patients of HIV/Aids from this region.
Hypolipidemic Activity of Olive Oil (Olea europaea) against High Fat Diet-Induced Nonalcoholic Fatty Liver Disease (NAFLD) in Mice  [PDF]
Farooq Ahmed Wani, Abdalla Z. Albahrawy, Shaik Rahiman
Open Journal of Pathology (OJPathology) , 2015, DOI: 10.4236/ojpathology.2015.53011
Abstract: Aim: The aim of the present study is to access the effect of olive oil supplementation against high fat diet induced fatty liver disease in mice. Methods: Mice were divided into five groups: Group I (normal diet), Group II (high fat diet), Group III (olive oil), Group IV and V (High Fat Diet along with olive oil). All mice were fed for 16 weeks with weight measurements every 2 weeks and then sacrificed. Biochemical analysis of blood samples was done and mice livers were histologically examined. Results: Group II mice showed significant increase in body weight as compared with Group I (p < 0.05). Group IV and V mice were significantly (p < 0.05) reduced in body weight as compared with Group II. Olive oil groups had significantly decreased triglyceride and low density lipoprotein levels as compared with Group II whereas high density lipoprotein levels were significantly increased (p < 0.05). The liver enzymes were significantly increased in Group II as compared with other groups (p < 0.05). Liver histopathology revealed drastically increased lipid droplets in Group II mice as compared with Group IV & V. Conclusion: Olive oil causes weight reduction, decreases the serum triglycerides, normalizes the liver enzymes and significantly reduces the accumulation of fat in liver. Therefore, olive oil may represent a potential therapeutic alternative for NAFLD and other fatty diseases.
Clinical, electrophysiological, and prognostic study of postinjection sciatic nerve injury: An avoidable cause of loss of limb in the peripheral medical service
Wani Maqbool,Sheikh Saleem,Ahmed Asrar
Annals of Indian Academy of Neurology , 2009,
Abstract: Background: Post injection sciatic nerve injury is a common cause of sciatic nerve mononeuropathy in the developing world largely due to inadequate health care facilites in the rural regions. Objective: The study was conducted to analyse the pattern of this nerve lesion in clinical and electrophysiological parameters and also to study the outcome in a conservatively treated cohort. Materials and Methods: One hundred and six patients who underwent evaluation at our laboratory from 2000 to 2006 for post injection sciatic neuropathy formed the study population. Twenty two of these were followed up (mean 6.6 months) for the outcome. Results: In the cases with full data, common peroneal division of the sciatic nerve was affected alone or predominantly. On follow up, 72% cases showed little or partial recovery. Thirty two percent patients had residual trophic changes and causalgia at their last visit. Conclusion: The majority of cases of postinjection sciatic nerve injury have poor prognosis on conservative treatment.
Cholesteatoma Eroding Cortex and Sinus Plate
Rouf Ahmed, Asef Wani, Manzoor Latoo
JK Science : Journal of Medical Education & Research , 2002,
Abstract: Not available
Assessment of Extent and Severity of Pellet Induced Abdominal Injuries, a Rare Variant of Weapon Violence: A Prospective Study  [PDF]
Azher Mushtaq, Atif Naeem Raja, Hilal Ahmad Wani, Shaukat A. Jeelani, Nazia Hilal, Ishfaq Ahmed Gilkar
Surgical Science (SS) , 2016, DOI: 10.4236/ss.2016.710064
Abstract: Background: The use of a Pellet gun, a form of short gun used for mob control in many conflict zones, has posed a serious challenge to the surgeons in assessing the extent of trauma caused by these pellets. Objectives: To study the role of conventional available investigations for trauma like ultrasonography and computed tomography scans in assessing the severity of the injuries caused by the pellets. Methodology: 50 patients having pellet injuries predominantly in abdomen without other associated trauma were included in the study. The decision for surgery was taken on the basis of clinical and CECT (Contrast Enhanced Computed Tomography) findings and these findings were then compared with intra-operative findings. Results: 30/50 patients were decided to be operated on the basis of Clinical and CECT findings. On exploration, it was observed that 18/33 patients really needed exploration while as 15/33 patients could have been managed conservatively. This was observed in next 20/50 patients who were put on conservative management with similar CECT findings. Of these 20 patients, 17 did well while as 3 were explored later in view of developing peritonitis and were found to have small bowel perforations. Conclusion: Conventional investigations for trauma like FAST and CECT abdomen are not ideal for assessing the severity of pellet induced abdominal visceral injuries which result in high rate of unnecessary laparotomies. Also the abdominal pellet trauma patients can be well managed conservatively until hemodynamically stable even though CT scan shows pellet penetration into peritoneal cavity or bowel lumen.
Cytoprotectant and Anti-Oxidant Effects of Olive Oil on Cadmium Induced Nephrotoxicity in Mice  [PDF]
Farooq Ahmed Wani, Mahrous AbdelBasset Ibrahim, Medhat M. Abdel Moneim, Abdul Rahman Hamdan A. Almaeen
Open Journal of Pathology (OJPathology) , 2018, DOI: 10.4236/ojpathology.2018.81004
Abstract: Background: Cadmium is a heavy metal having toxic effects on most organ systems of the body. Objectives: We aim to investigate the postulated protective properties of olive oil in Cadmium-induced renal toxicity in mice by utilizing standard biomarkers of renal toxicity, oxidative stress and histopathological characterization. Materials and Methods: Forty mice were randomly divided into four groups of 10 mice each. Group 1 served as control group, group 2 was given Extra-virgin olive oil orally, group 3 was given Cadmium chloride and group 4 was given Cadmium chloride with Extra-virgin olive oil. At the end of the experimental period, biochemical analysis histopathology of kidney was done. Results: The present study depicted that blood urea, serum creatinine and the antioxidant markers (Superoxide dismutase, Glutathione peroxidase and Catalase) levels were significantly increased in group 3 compared to group 1 and 2. After administration of Extra-virgin olive oil with Cadmium in group 4, the levels of those markers significantly improved. Histopathology of the renal tissue showed severe damage of glomeruli, severely congested blood vessels and marked dilatation of Bowman’s capsule in group 3 with improvements of these changes in group 4. Conclusion: This study suggests that Extra-virgin olive oil can be used as a cost effective safe anti-oxidative agent in the prevention of Cadmium toxicity.
Albendazole Therapy in Ascariasis
Ishtyak Ahmed Mir ,Nazir Ahmed Wani, Rekha Patnaik
JK Science : Journal of Medical Education & Research , 2003,
Abstract: Patients in the paediatric age group with moderate to severe intestinal ascariasis were treated withvarious antihelminthic dJugs. Albendazole, Pyrantel pamoate and Levamisole were used. Comparisonofthe percentage cure rate, was made and albendazole was found to be the most effective in 92.26%of patients followed by pyrantel pamoate and levamisole in 80.82% and 64.70% of the patientsrespectively.
Radio-Imaging in Ascariasis
Ishtyak Ahmed Mir ,Nazir Ahmed Wani, Rekha Patnaik, Annil Mahajan
JK Science : Journal of Medical Education & Research , 2002,
Abstract: Not available
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