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Search Results: 1 - 10 of 25566 matches for " Shaojiang Dong "
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Dynamics of Entanglement in the Cavity with Nonlinear Medium  [PDF]
Shaojiang Du, Hairan Feng
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.45086
Abstract:

We investigate the evolution of initial entangled two-atom in cavity with single-mode light field. Using the method of negative eigenvalue of partially transposed matrix we analysis the evolution of the entanglement of the two-atom in a field of number state and Kerr-media environment and find that entanglement sudden death phenomenon occurs in the number of particles field. When the atoms interact with the Kerr medium, we obtain that the phenomenon of sudden death can be eliminated in the particle-number field, and the entanglement of two-atom oscillates around a high-value.

Bearing Degradation Process Prediction Based on the Support Vector Machine and Markov Model
Shaojiang Dong,Shirong Yin,Baoping Tang,Lili Chen,Tianhong Luo
Shock and Vibration , 2014, DOI: 10.1155/2014/717465
Abstract: Predicting the degradation process of bearings before they reach the failure threshold is extremely important in industry. This paper proposed a novel method based on the support vector machine (SVM) and the Markov model to achieve this goal. Firstly, the features are extracted by time and time-frequency domain methods. However, the extracted original features are still with high dimensional and include superfluous information, and the nonlinear multifeatures fusion technique LTSA is used to merge the features and reduces the dimension. Then, based on the extracted features, the SVM model is used to predict the bearings degradation process, and the CAO method is used to determine the embedding dimension of the SVM model. After the bearing degradation process is predicted by SVM model, the Markov model is used to improve the prediction accuracy. The proposed method was validated by two bearing run-to-failure experiments, and the results proved the effectiveness of the methodology. 1. Introduction Bearing is one of the most important components in rotating machinery. Accurate bearing degradation process prediction is the key to effective implement of condition based maintenance and can prevent unexpected failures and minimize overall maintenance costs [1, 2]. To achieve effective degradation process prediction of the bearing, firstly, the features should be extracted from the collected vibration data. Then, based on the extracted features effectively prediction models should be selected [3]. Feature extraction is the process of transforming the raw vibration data collected from running equipment to relevant information of health condition. There are three types of methods to deal with the raw vibration data: time domain analysis, frequency domain analysis, and time-frequency domain analysis. The three types of methods are often chosen to extract the feature. For example, Yu [4] chose the time domain and the frequency domain transform to describe the characteristics of the vibration signals. Yan et al. [5] chose the short-time Fourier transform to extract the features. Ocak et al. [6] chose the wavelet packet transform to extract the feature of bearing wear information. Because the frequency features from FFT analysis results often tend to average out transient vibrations and thus not providing a wholesome measure of the bearing health status, in this paper, the time domain and the time-frequency domain characteristics are used to extract the original features. Although the original features can be extracted, they are still with high dimension and include
Tubulointerstitial Macrophage Accumulation is Regulated by Sequentially Expressed Osteopontin and Macrophage Colony-Stimulating Factor: Implication for the Role of Atorvastatin
Shaojiang Tian,Guohua Ding,Ruhan Jia,Guili Chu
Mediators of Inflammation , 2006, DOI: 10.1155/mi/2006/12919
Abstract: Infiltration and local proliferation are known factors that contribute to tubulointerstitial macrophage accumulation. This study explored the time course of these two contributors' roles as tubulointerstitial inflammation and fibrosis progressing, and evaluated the mechanisms of the protective effect of atorvastatin. Unilateral ureteral obstructive (UUO) rats were treated with atorvastatin (10 mg/Kg) or vehicle. Expression of osteopontin (OPN) and macrophage colony-stimulating factor (M-CSF) was evaluated by RT-PCR and immunohistochemistry. Immunohistochemistry staining of ED1 was used to assess macrophage accumulation in interstitium. Histological evaluation was performed to semiquantify tubulointerstitial fibrosis. The results showed that on day 3 after UUO operation, OPN expression significantly increased and positively correlated with the number of the interstitial ED1
Tubulointerstitial Macrophage Accumulation is Regulated by Sequentially Expressed Osteopontin and Macrophage Colony-Stimulating Factor: Implication for the Role of Atorvastatin
Shaojiang Tian,Guohua Ding,Ruhan Jia,Guili Chu
Mediators of Inflammation , 2006,
Abstract: Infiltration and local proliferation are known factors that contribute to tubulointerstitial macrophage accumulation. This study explored the time course of these two contributors' roles as tubulointerstitial inflammation and fibrosis progressing, and evaluated the mechanisms of the protective effect of atorvastatin. Unilateral ureteral obstructive (UUO) rats were treated with atorvastatin (10 mg/Kg) or vehicle. Expression of osteopontin (OPN) and macrophage colony-stimulating factor (M-CSF) was evaluated by RT-PCR and immunohistochemistry. Immunohistochemistry staining of ED1 was used to assess macrophage accumulation in interstitium. Histological evaluation was performed to semiquantify tubulointerstitial fibrosis. The results showed that on day 3 after UUO operation, OPN expression significantly increased and positively correlated with the number of the interstitial ED1+ cells, while on day 10, M-CSF expression upregulated and correlated with interstitial ED1 + cells. In atorvastatin treatment group, the increments of these two factors were attenuated significantly at the two time points, respectively. ED1+ cell accumulation and fibrosis also ameliorated in the treatment group. For all the samples of UUO and treatment group on day 10, ED 1+ cells also correlated with interstitial fibrosis scores. The results suggest that OPN may induce the early macrophage/monocyte infiltration and M-CSF may play an important role in regulating macrophage accumulation in later stage of UUO nephropathy. Statin treatment decreases interstitial inflammation and fibrosis, and this renoprotective effect may be mediated by downregulating the expression of OPN and M-CSF.
Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis
Shaojiang Tian,Junming Tang,Huihui Liu,Liping Wang,Jianming Shen,Junfeng Li,Yanjie Gan
Experimental Diabetes Research , 2012, DOI: 10.1155/2012/209567
Abstract: There is growing evidence suggesting that glomerular endothelial cell proliferation and angiogenesis may be responsible for the pathophysiological events in the early stage of diabetic nephropathy. This study was designed to investigate the factors related to glomerular endothelial cell proliferation and glomerular angiogenesis and assess the effect of propyl gallate on preventing these disorders in diabetic rats. We found that glomerular hypertrophy, glomerular mesangial matrix expansion, and albuminuria were significantly increased in DN rats. CD31
Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats
Yixiong Chen, Shaoping Zheng, Dan Qi, Shaojiang Zheng, Junli Guo, Shuling Zhang, Zhihong Weng
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0046512
Abstract: Notch signaling is essential to the regulation of cell differentiation, and aberrant activation of this pathway is implicated in human fibrotic diseases, such as pulmonary, renal, and peritoneal fibrosis. However, the role of Notch signaling in hepatic fibrosis has not been fully investigated. In the present study, we show Notch signaling to be highly activated in a rat model of liver fibrosis induced by carbon tetrachloride (CCl4), as indicated by increased expression of Jagged1, Notch3, and Hes1. Blocking Notch signaling activation by a γ-secretase inhibitor, DAPT, significantly attenuated liver fibrosis and decreased the expression of snail, vimentin, and TGF-β1 in association with the enhanced expression of E-cadherin. The study in vitro revealed that DAPT treatment could suppress the EMT process of rat hepatic stellate cell line (HSC-T6). Interestingly, DAPT treatment was found not to affect hepatocyte proliferation in vivo. In contrast, DAPT can inhibit hepatocyte apoptosis to some degree. Our study provides the first evidence that Notch signaling is implicated in hepatic fibrogenesis and DAPT treatment has a protective effect on hepatocytes and ameliorates liver fibrosis. These findings suggest that the inhibition of Notch signaling might present a novel therapeutic approach for hepatic fibrosis.
Clinical Characteristics of Nephrotoxicity of Caulis AristolochiaeManshuriensis and Related Experimental Research
木通肾毒性的临床特点及实验研究概况

Hu Jinguan,Long Shaojiang,Gu Jian,
胡锦官
,龙绍疆,顾健

世界科学技术-中医药现代化 , 2003,
Abstract: The nephrotoxicity of Caulis Aristolochiae Manshuriensis has got more and more attention in China and abroad. This article makes the textual research of Caulis Aristolochiae Manshuriensis from the viewpoint of herbalism and summarizes the clinical characteristics of its nephrotoxicity as well as its experimental research carried out in animal models, toxicity mechanisms and pharmacokinetics in recent years.
Chlorophyll Deficiency in the Maize elongated mesocotyl2 Mutant Is Caused by a Defective Heme Oxygenase and Delaying Grana Stacking
Dianyi Shi, Xu Zheng, Liang Li, Wanhuang Lin, Wenjun Xie, Jianping Yang, Shaojiang Chen, Weiwei Jin
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080107
Abstract: Background Etiolated seedlings initiate grana stacking and chlorophyll biosynthesis in parallel with the first exposure to light, during which phytochromes play an important role. Functional phytochromes are biosynthesized separately for two components. One phytochrome is biosynthesized for apoprotein and the other is biosynthesized for the chromophore that includes heme oxygenase (HO). Methodology/Principal Finding We isolated a ho1 homolog by map-based cloning of a maize elongated mesocotyl2 (elm2) mutant. cDNA sequencing of the ho1 homolog in elm2 revealed a 31 bp deletion. De-etiolation responses to red and far-red light were disrupted in elm2 seedlings, with a pronounced elongation of the mesocotyl. The endogenous HO activity in the elm2 mutant decreased remarkably. Transgenic complementation further confirmed the dysfunction in the maize ho1 gene. Moreover, non-appressed thylakoids were specifically stacked at the seedling stage in the elm2 mutant. Conclusion The 31 bp deletion in the ho1 gene resulted in a decrease in endogenous HO activity and disrupted the de-etiolation responses to red and far-red light. The specific stacking of non-appressed thylakoids suggested that the chlorophyll biosynthesis regulated by HO1 is achieved by coordinating the heme level with the regulation of grana stacking.
Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis
Shaojiang Tian,Junming Tang,Huihui Liu,Liping Wang,Jianming Shen,Junfeng Li,Yanjie Gan
Journal of Diabetes Research , 2012, DOI: 10.1155/2012/209567
Abstract: There is growing evidence suggesting that glomerular endothelial cell proliferation and angiogenesis may be responsible for the pathophysiological events in the early stage of diabetic nephropathy. This study was designed to investigate the factors related to glomerular endothelial cell proliferation and glomerular angiogenesis and assess the effect of propyl gallate on preventing these disorders in diabetic rats. We found that glomerular hypertrophy, glomerular mesangial matrix expansion, and albuminuria were significantly increased in DN rats. CD31+ endothelial cells significantly increased in glomerulus of diabetic rats. Double immunofluorescence staining showed some structurally defective vasculus tubes in glomerulus. Real-time PCR and western blot demonstrated the glomerular eNOS expression remained at the same level, while remarkable decreased NO productions and suppressed eNOS activities were observed in diabetic rats. Treatment with propyl gallate improved glomerular pathological changes, reduced endothelial cell proliferation, decreased albuminuria, and restored eNOS activity, but did not alter eNOS expression. These data suggest that endothelial cell proliferation and immature angiogenesis may be the contributors to progression of DN. Propyl gallate is a potential novel therapeutic agent on prevention of diabetic nephropathy. 1. Introduction Diabetic nephropathy is the most frequent cause of chronic kidney disease and usually quickly progresses to end-stage renal disease requiring renal replacement therapy. Early alterations in diabetic nephropathy include development of glomerular hyperfiltration and glomerular hypertrophy, followed by increased urinary albumin excretion and eventually leading to glomerular sclerosis [1]. Although intensified controls of hyperglycemia, hypertension, and proteinuria slow down the progression of DN, these therapies do not sufficiently retard the progression of DN [2]. The exact mechanism underlying the pathogenesis of DN is yet clear. However, there is ample evidence for the involvement of endothelial cell proliferation and angiogenesis, the development of new blood vessels from preexisting ones, in facilitating glomerular hypertrophy in early stage of DN [3]. In addition, some antiangiogenic agents ameliorate glomerular hypertrophy and hyperfiltration as well as urinary albumin excretion in early stage of DN [4, 5]. The results of these studies strongly suggest that glomerular angiogenesis may be responsible for the pathophysilogical events in the early stage of DN. Microalbuminuria is considered an early
The Effect of Knowledge Management on Product Innovation - Evidence from the Chinese Software Outsourcing Vendors  [PDF]
Dong Yang
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.31003
Abstract: The knowledge acquisition and exploitation are becoming more and more for local vendors in offshore outsourcing cooperation. In the process of product innovation, internal knowledge sharing (IKS), external knowledge acquisition (EKA) and their interactive relationship is discussed. Through the using of the method of 3SLS, the results of STATA indicate that IKS and EKA positively complement for product innovation. Furthermore, the result of SPSS reveals that knowledge exploitation mediates the (IKS) EKA and product innovation.
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