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Search Results: 1 - 10 of 78261 matches for " Shande Chen "
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Re-Parameterization the Logistic Model in Assessing Changes in the Baroreceptor Reflex  [PDF]
Shande Chen, Xiangrong Shi
Neuroscience & Medicine (NM) , 2011, DOI: 10.4236/nm.2011.22016
Abstract: The logistic model is frequently used to describe the nonlinear relationship between systemic arterial pressure (SAP) and carotid sinus pressure (CSP). In this paper, we propose using maximum gain and saturation as parameters in the logistic model. By this method, the estimates and standard errors together with confidence intervals for maximum gain and saturation are direct outputs from the curve fitting, which also makes it easy to perform various hypotheses testing on these quantities. The method is illustrated by real life data from a study on the carotid baroreflex function during infusion of sodium nitroprusside, in which seven healthy, young men who were clinically proved to be free from any disease were studied. Their heart rate, arterial blood pressure and central venous pressure were measured. Neck pressure and neck suction protocol was carried out to selectively elicit changes in CSP and the responsiveness of SAP. Data were analyzed and compare before and after nitroprusside infusion. Our results showed that nitroprusside significantly decreased arterial blood pressure and central venous pressure, and significantly increased heart rate, and significantly augmented maximum gain of the carotid baroreflex function.
Data quality assurance and quality control measures in large multicenter stroke trials: the African-American Antiplatelet Stroke Prevention Study experience
DeJuran Richardson, Shande Chen
Trials , 2001, DOI: 10.1186/cvm-2-3-115
Abstract: The clinical trial is the 'gold standard' for obtaining definitive information about medical interventions. Collecting accurate data on patients who are being followed under specific and controlled circumstances lies at the heart of the mission of a clinical trial. Ensuring that the accumulating data are as free of anomalies as possible is of utmost importance to the soundness of the process. Indeed, having no errors in the data and no occurrences of protocol violations is the goal, but the amount of resources required to accomplish such a goal is prohibitive. At the very least, effective procedures should be instituted in every trial to limit inadvertent errors, as well as fraudulent activity, even though it is believed that fraud occurs rarely [1]. Failure to plan and implement an effective quality assurance program within a trial can not only adversely affect the scientific impact of the trial itself, but can also affect public confidence in the reliability and effectiveness of clinical trials within medical research.Gassman et al [2] and McFadden [3] provided comprehensive literature reviews and detailed discussions of the necessity and structure of effective data quality assurance and quality control programs within a clinical trial. In addition to standard data quality control methods [2], the African-American Antiplatelet Stroke Prevention Study (AAASPS) [4] developed unique methods for accomplishing the goals of these programs. The AAASPS is a two-arm, multicenter, randomized, double-blind clinical trial comparing ticlopidine and aspirin therapy in patients who experience an ischemic stroke within 90 days of randomization. This clinical trial has been enrolling and following patients since December 1995. The primary objective is to assess the efficacy and safety of the two treatments in the prevention of recurrent stroke, myocardial infarction, and vascular death in 1800 African-American patients treated for 2 years. Here we discuss some of the components of
The Impact of the 2002 Delaware Smoking Ordinance on Heart Attack and Asthma
John Moraros,Yelena Bird,Shande Chen,Robert Buckingham,Richard S. Meltzer,Surasri Prapasiri,Luis H. Solis
International Journal of Environmental Research and Public Health , 2010, DOI: 10.3390/ijerph7124169
Abstract: In the United States, smoking is the leading cause of death - having a mortality rate of approximately 435,000 people in 2000—accounting for 8.1% of all US deaths recorded that year. Consequently, we analyzed the Delaware Hospital Discharge Database, and identified state and non-state residents discharged with AMI or asthma for the years 1999 to 2004. Statistical data analysis compared the incidence of AMI or asthma for each group before (1999–2002) and after (2003–2004) the amendment. As a result, we found that pre-ordinance and post-ordinance quarterly rates of AMI for Delaware residents were 451 (se = 21) and 430 (se = 21) respectively, representing a 4.7% reduction. Over the same time period, there was negligible change in the incidence of AMI for non-Delaware residents. After adjusting for population growth, the Risk Ratio (RR) for asthma in Delaware residents post-ordinance was 0.95 (95% CI, 0.90 to 0.999), which represented a significant reduction (P = 0.046). By comparison, non-Delaware residents had an increased RR for asthma post-ordinance of 1.62 (95% CI, 1.46 to 1.86; P < 0.0001).The results suggest that Delaware’s comprehensive non-smoking ordinance effectively was associated with a statistically significant decrease in the incidence of AMI and asthma in Delaware residents when compared to non-Delaware residents.
An Improved Collocation Meshless Method Based on the Variable Shaped Radial Basis Function for the Solution of the Interior Acoustic Problems
Shuang Wang,Shande Li,Qibai Huang,Kun Li
Mathematical Problems in Engineering , 2012, DOI: 10.1155/2012/632072
Abstract: As an efficient tool, radial basis function (RBF) has been widely used for the multivariate approximation, interpolating continuous, and the solution of the particle differential equations. However, ill-conditioned interpolation matrix may be encountered when the interpolation points are very dense or irregularly arranged. To avert this problem, RBFs with variable shape parameters are introduced, and several new variation strategies are proposed. Comparison with the RBF with constant shape parameters are made, and the results show that the condition number of the interpolation matrix grows much slower with our strategies. As an application, an improved collocation meshless method is formulated by employing the new RBF. In addition, the Hermite-type interpolation is implemented to handle the Neumann boundary conditions and an additional sine/cosine basis is introduced for the Helmlholtz equation. Then, two interior acoustic problems are solved with the presented method; the results demonstrate the robustness and effectiveness of the method.
Research on the Incentive Mechanism of Hidilao Hotpot’s Employees Based on Grounded Theory  [PDF]
Chen Chen
Journal of Human Resource and Sustainability Studies (JHRSS) , 2018, DOI: 10.4236/jhrss.2018.61031
Abstract: The traditional classical incentive model only reveals the general rule of organizational incentive, and does not give specific operation rules. The matching between organizational incentives and employee needs is still black box, and it does not reveal its core operation mechanism from the perspective of mechanism. This paper took through the literature review, the Hidilao Hotpot company as a case study, through a variety of ways to collect data, the use of grounded theory to encode data analysis, and ultimately extracted 58 concepts, 26 sub-areas, 7 main areas, concluded that the Hidilao Hotpot Employee motivation formed the path, and ultimately extracted the micro-level employee motivation mechanism model. The research result of this article comes from the practice of the enterprise, which has enlightenment to the organizational incentive of the traditional catering industry and also provides a micro-research perspective and systematic mechanism research for the incentive field.
Digital Image Watermarking Based on Mixed Error Correcting Code  [PDF]
Yonghong Chen, Jiancong Chen
Journal of Information Security (JIS) , 2012, DOI: 10.4236/jis.2012.32018
Abstract: In this paper, we present a novel technique based on a mixed Error Correcting Code(ECC)-the convolutional code and the repetition code to enhance the robustness of the embedded watermark. Before embedding, the binary watermark is scanned to one-dimension sequence and later inputted into the (3, 1, 2) convolutional encoder and (3, 1) repetition encoder frame by frame, which will improve the error correcting capability of decoder. The output code sequence is scanned to some matrixes as the new watermark messages. The watermarking is selected in low frequency band of the Discrete Wavelet Transform (DWT) and therefore it can resist the destruction of image processing. Experimental results are presented to demonstrate that the robustness of a watermark with mixed ECC is much higher than the traditional one just with repetition coding while suffering JPEG lossy compression, salt and pepper noise and center cutting processing.
Operator Equation and Application of Variation Iterative Method  [PDF]
Ning Chen, Jiqian Chen
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.38127
Abstract: In this paper, we study some semi-closed 1-set-contractive operators A and investigate the boundary conditions under which the topological degrees of 1-set contractive fields, deg (I-A, Ω, p) are equal to 1. Correspondingly, we can obtain some new fixed point theorems for 1-set-contractive operators which extend and improve many famous theorems such as the Leray-Schauder theorem, and operator equation, etc. Lemma 2.1 generalizes the famous theorem. The calculation of topological degrees and index are important things, which combine the existence of solution of for integration and differential equation and or approximation by iteration technique. So, we apply the effective modification of He’s variation iteration method to solve some nonlinear and linear equations are proceed to examine some a class of integral-differential equations, to illustrate the effectiveness and convenience of this method.
Blow-Up and Attractor of Solution for Problems of Nonlinear Schrodinger Equations  [PDF]
Ning Chen, Jiqian Chen
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.312263
Abstract: In this paper, the authors study the blow-up of solution for a class of nonlinear Schrodinger equation for some initial boundary problem. On the other hand, the authors give out some analyses and that new conclusion by Eigen-function method. In last section, the authors check the nonlinear parameter for light rule power by using of parameter method to get ground state and excite state correspond case, and discuss the global attractor of some fraction order case, and combine numerical test. To illustrate this physics meaning in dimension d = 1, 2 case. So, by numerable solution to give out these wave expression.
Some Approximation in Cone Metric Space and Variational Iterative Method  [PDF]
Ning Chen, Jiqian Chen
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.312276
Abstract: In this paper, we give some new results of common fixed point theorems and coincidence point case for some iterative method. By using of variation iteration method and an effective modification of He’s variation iteration method discusses some integral and differential equations, we give out some new conclusion and more new examples.
Photoconductive Effect of Liquid and Utilization of Solar Energy  [PDF]
Ziwei Chen, Shihao Chen
Open Journal of Physical Chemistry (OJPC) , 2014, DOI: 10.4236/ojpc.2014.41003
Abstract:

Experiments described in this paper show that there is the photoconductive effect of liquid, i.e. when light shines into a sort of alkali, acid or salt solution, the conductivity of the solution will increase. The mechanism of the effect is explained as follows. When hydrated ions in the solution absorb photons with their high enough energies, they will decompose to naked ions and water-molecules. The naked ions can reach an anode or a cathode more easily and faster than the hydrated ions; It is possible that when a molecule in the solution absorbs a photon with its high enough energy, it will decompose to negative and positive ions. Based on the effect, a device producing hydrogen by the solar-energy had been devised.

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