Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Search Results: 1 - 10 of 373 matches for " Shahriar Dabiri "
All listed articles are free for downloading (OA Articles)
Page 1 /373
Display every page Item
Garlic effects on reproductive complications of diabetes mellitus in male rats
Akram Abdolahnejad,Ali Gol,Shahriar Dabiri
Physiology and Pharmacology , 2009,
Abstract: Introduction: Diabetes mellitus has adverse effects on male sexual and reproductive functions in human and animals. Diabetes results in reduced fertility and libido. Medicinal plants have attracted much attention in controlling many diseases such as diabetes. In the present study, we aimed to investigate the effect of garlic juice on testicular damage. Methods: Forty male rats (250±20) were divided into 5 groups as follows: 1- Group normal (N) 2- Group Normal+Garlic (N+G) received garlic juice for 6 weeks. 3- Diabetic (D) received streptozotocin (STZ), 60mg/kg BW/i.p. 4- Group diabetic+garlic before (D+Gb) received garlic juice for 3 weeks before STZ injection and continued for more 3 weeks. 5- Group diabetic+garlic after (D+Ga) three days after STZ injection, they received garlic juice for 3 weeks. Garlic juice was given by gavage (1ml/100g BW). Number of leydig cells, testis weight, serum levels of testosterone and estradiol were assessed. Results: diabetic rats showed a marked decrease in the number of leydig cells, testis weight, serum levels of testosterone and estradiol. Garlic juice significantly increased the number of leydig cells, testis weight, serum levels of testosterone and estradiol in group 4 and 5 compared to group 3. The diabetic group receiving garlic before STZ injection showed more amelioration in complications than that receiving it after STZ injection. Conclusion: these results suggest that garlic juice supplementation could play both preventive and therapeutic role on testicular damage in diabetic rats.
Effect of the methanolic extract of Daucus carota seeds on the carbohydrate metabolism and morphology of pancreas in type I diabetic male rats
Banafsheh Ranjbar,Iran Pouraboli,Mitra Mehrabani,Shahriar Dabiri
Physiology and Pharmacology , 2010,
Abstract: Introduction: Antioxidant agents have beneficial effects in diabetes mellitus. Daucus carota seeds extract has been shown to possess antioxidant activity. In this study, the effect of the methanolic extract of Daucus carota seeds on carbohydrate metabolism and morphology of pancreas was investigated in type I diabetic male rats. Methods: Type I diabetes mellitus was induced in male Wistar rats by injection of 70 mg/kg, i. p. of streptozotocin. Blood samples were collected from the eye cavernousa sinus, before and 5 days after injections for measurement of glucose and insulin. Diabetes was confirmed in rats that had FBS levels above 250 mg/dl. Diabetic rats were divided to 5 groups that received 100, 200 and 300 mg/kg of the extract, glibenclamide (600 μg/kg) and distilled water (0.5 ml) daily for 6 days by gastric gavage. After 6 days, they were sacrificed by decapitation and fasting blood samples were collected and serum levels of glucose and insulin were measured by spectrophotometric and ELISA methods, respectively, by using commercial kits. The pancreas of the rats were dissected out and fixed in 10% formaldehyde for histological studies. Results: Administration of all doses of Daucus carota seeds extract and glibenclamide for 6 days significantly decreased serum glucose levels, however, only 300 mg/kg of the extract as well as glibenclamide significantly increased insulin serum levels. Furthermore the extract and glybenclamide improved pancreas asinuses and islets as the number of islets significantly increased in rats receiving 100 mg/kg of the extract or glibenclamide. Conclusion: D. carota seeds extract has hypoglycemic effect by increasing insulin secretion and improvement of the pancreas.
Investigating the Preventive Effect of Garlic on Blood Glucose Levels and Histopathology of Pancreas in Streptozotocin-induced Diabetic Rats
Fatemeh Masjedi,Ali Gol,Shahriar Dabiri,Abdoreza Javadi
Physiology and Pharmacology , 2009,
Abstract: Introduction: The preventive antidiabetic effects of garlic juice on blood glucose levels and pancreas tissue was evaluated in STZ-induced diabetic rats. Methods: 40 male rats were divided into five groups of 8 rats each. 1) Normal group (N), 2) Normal+Garlic group (N+G) received 1 ml garlic juice/100g BW/day for 6 weeks, 3) Diabetic group (D) injected with streptozotocin (60 mg/kg BW,i.p.), 4) Diabetic + Garlic_before group (D+Gb) received garlic juice for 6 weeks, but at the end of third week, they were injected with STZ, 5) Diabetic+Garlic_after group (D+Ga) received garlic juice for 3 weeks, after they were injected with STZ. At the end of the experiment, serial sections of pancreas were prepared and stained with H&E for light microscope investigations. Results: Serum glucose levels were significantly increased (p<0.05) in D group in comparison with other groups. There was no significant difference between D+Gb group and N and N+G groups. Body, pancreas, and relative weights was significantly decreased (p<0.05) in D group in comparison with other groups. In D+Gb and D+Ga groups pancreas weight showed no significant difference with the normal group. In D group decrease of pancreatic islet numbers and their mean diameter, atrophy and vacuolation in parenchyma of pancreatic islets were detected. These abnormal histological signs were dramatically decreased in D+Gb group compared to D group. In D+Ga group, dramatical but slighter effects of garlic juice on the histopathological changes of the pancreas were observed. Conclusion: Based on these results, it is thought that garlic juice has favorable effects in preventing changes in blood glucose levels, body and pancreas weights, and the histopathological changes in pancreas in STZ-induced diabetes.
A Comparative In Vivo Study of Tissue Reactions to Four Suturing Materials
Shahla Kakoei,Fahimeh Baghaei,Shahriar Dabiri,Masoud Parirokh
Iranian Endodontic Journal , 2010,
Abstract: INTRODUCTION: The purpose of this study was to compare the histopathologic reaction of four suturing materials: silk, polyvinylidene fluoride (PVDF), polyglycolic acid, and catgut in the oral mucosa of albino rabbits. MATERIALS AND METHODS: The twenty-one male mature albino rabbits which were used in this study were randomly divided into three groups of seven each. Silk, PVDF, polyglycolic acid and catgut suture materials were tested in the oral mucosa of these animals. The animals were sacrificed 2, 4, and 7 days after suturing. Two pathologists evaluated the samples by determining the presence and level of inflammation, granulation tissue, and fibrosis formation. Data were statistically analyzed by Kruskal Wallis and Mann-Whitney U tests. RESULTS: Histological features of the samples showed that PVDF and plain catgut suture materials produced more fibrous tissue (favorable response) on the fourth day in comparison with silk suture (P=0.02). Also, in the 7-day samples PVDF sutures produced the mildest inflammation when compared with the silk sutures (P=0.015). CONCLUSION: According to the results of this study, it can be convey that PVDF suture materials created mild tissue reactions and can be a reasonable candidate for suturing oral tissues.
"[99mTc-DMSA (V)] in Detection of Metastases of Medullary Thyroid Carcinoma "
Shahram Dabiri
Iranian Journal of Nuclear Medicine , 2006,
Abstract: Introduction: Medullary thyroid carcinoma (MTC) is a rare thyroid cancer secreting calcitonin (CT) which is the most sensitive and specific tumor marker for MTC. This type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. The aim of this study was to assess the sensitivity and specificity of [99mTc-DMSA (V)] whole body scan (WBS) in detection of metastases in MTC. Methods: This descriptive and prospective study was performed in 15 patients with MTC referred to our nuclear medicine centre since 2004 to 2005. These patients were compared regarding age, sex, and duration of the disease. Sensitivity and specificity of each diagnostic modality in detection of metastases were calculated and compared statistically. Results: [99mTc-DMSA (V)] showed 91% sensitivity and 75% specificity as compared with serum calcitonin as gold standard. The figures for CT scan were 82% and 45%, respectively. CEA showed 64% sensitivity and 50% specificity. Conclusion: It is concluded that despite the slightly lower sensitivity and specificity of [99mTc-DMSA (V)] as compared to calcitonin (Gold-standard method), this radiotracer can be used for identification of recurrence or metastasis of medullary thyroid carcinoma.
99mTc-MIBI Scintigraphy Versus 131I Whole Body Scan in the Follow-up of Patients with Differentiated Thyroid Carcinoma
Dabiri Sh.
Journal of Medical Sciences , 2006,
Abstract: Thyroid cancer is the most common endocrine malignancy. More than 90% of primary thyroid cancers are papillary or follicular types, together termed Differentiated Thyroid Cancers (DTC). The aim of this study was to assess to what extent 99mTc-MIBI Whole Body Scan (WBS) improves detectability of negative 131I scan in follow-up of patients with DTC. This descriptive and prospective study was performed over 40 patients with DTC who were referred to Dr. Dabiri Nuclear Medicine Center from 2004-2005. Six months after total thyroidectomy and 131I ablation therapy, all patients underwent 131I 99mTc-MIBI WBS. Serum thyroglobulin was measured by radioimmunoassay method. Serum TSH levels was >30 μU mL-1 in all patients. 99mTc-MIBI showed 93.75% sensitivity and 87.5% specificity. The figures for 131I scan were 87.5 and 100%, respectively. It is concluded that considering the slightly higher sensitivity of 99mTc-MIBI, this radio tracer can be used for follow-up of patients with negative 131I study and patients on suppression therapy.
Investigation on the Geochemical Distribution of REE and Heavy Metals in Western Part of Jalal-Abad Iron Ore Deposit, Zarand, SE of Iran  [PDF]
Abdollah Yazdi, Sajad Ziaaldini, Rahim Dabiri
Open Journal of Ecology (OJE) , 2015, DOI: 10.4236/oje.2015.59038
Abstract: The Jalal-Abad iron ore deposit, with a reserve of more than 200 Mt ore, is located in NW of Zarand region, southeastern Iran. The ore deposit occurs in the form of an elongated lens-shaped body incorporated in a folded structure of Rizu volcano-sedimentary unit. Mineralization occurred mainly in siltstones, acidic volcanic rocks and dolomitized limestones. The ore minerals include magnetite, hematite, pyrite, chalcopyrite, goethite, malachite and azurite. Chloritization and silicification are the two most widespread alteration types in the Jalal-Abad area. Cu and Ti are among the associated elements with iron in the ore samples. In comparison, the concentrations of Cu, Ti and REE are relatively low in the samples analyzed. The combined concentrations of Ce, La and Y show that geochemical background values for most areas have been measured. The Pearson correlation coefficient values and the results of cluster and principal component analyses indicate a strong correlation between REE, La, Ce, and Y with Sr in the same geochemical group suggesting a common source for these elements. A close association between Cu and Cl with metasomatic host rock and among Pb, Zn and Ba with carbonate host rocks is observed.
Legal System Governing on Water Pollution in Iran  [PDF]
Flora Heidari, Farhad Dabiri, Mehdi Heidari
Journal of Geoscience and Environment Protection (GEP) , 2017, DOI: 10.4236/gep.2017.59004
Abstract: In the present era, water contamination represents one of the considerable environmental problems. Population growth along with ever increasing industrial developments has resulted in the contamination of most of the water resources in the world, bringing about serious problems for humans and other living organisms. According to the human life on earth depends on the way different water resources are exploited, the most important way to preserve the quality of water resources is to codify appropriate regulations and standards and develop plans for proper and principled implementation of them. Therefore, it seems to be necessary to take required actions to manage water resources optimally. In this regard, one of the most significant legal tools is the law. Following a descriptive-analytic approach, the present research aims to consider legal challenges in the context of water contamination briefly. Investigations indicate that, given the limitations in water resources, in future, water contamination will raise serious problems for the country should the solutions and measures required for tackling this issue are not well incorporated into respective regulations. As such, in order to systemize the activities within this scope, it is necessary to codify a comprehensive act about different water-related topics, so as to cover all separate and sparse pieces of regulations on water. Further, acquiring help from experts when preparing the regulations with an emphasis on the inhibitory role of penalties, roles of NGOs and culture-making in the society will contribute to the successful legal protection of the quality of water resources.
Phosphotungstic Acid: An Efficient, Cost-effective and Recyclable Catalyst for the Synthesis of Polysubstituted Quinolines
Minoo Dabiri,Sahareh Bashiribod
Molecules , 2009, DOI: 10.3390/molecules14031126
Abstract: Phosphotungstic acid (H3PW12O40) was used as an efficient and recyclable catalyst for the synthesis of polysubstituted quinolines through the Friedl?nder condensation of 2-aminoarylketone with carbonyl compounds, which was achieved by conventional heating under solvent-free conditions.
Applying Activity Based Costing (ABC) Method to Calculate Cost Price in Hospital and Remedy Services
A Rajabi,A Dabiri
Iranian Journal of Public Health , 2012,
Abstract: Background: Activity Based Costing (ABC) is one of the new methods began appearing as a costing methodology in the 1990. It calculates cost price by determining the usage of resources. In this study, ABC method was used for calculating cost price of remedial services in hospitals.Methods: To apply ABC method, Shahid Faghihi Hospital was selected. First, hospital units were divided into three main departments: administrative, diagnostic, and hospitalized. Second, activity centers were defined by the activity analysis method. Third, costs of administrative activity centers were allocated into diagnostic and operational departments based on the cost driver. Finally, with regard to the usage of cost objectives from services of activity centers, the cost price of medical services was calculated.Results: The cost price from ABC method significantly differs from tariff method. In addition, high amount of indirect costs in the hospital indicates that capacities of resources are not used properly.Conclusion: Cost price of remedial services with tariff method is not properly calculated when compared with ABC method. ABC calculates cost price by applying suitable mechanisms but tariff method is based on the fixed price. In addition, ABC represents useful information about the amount and combination of cost price services.
Page 1 /373
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.