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Tumor markers and kinetics in prostate cancer: a mini-review
Farooq Ahmad Ganie,Mohd Lateef Wani,Shadab Nabi Wani,Mohd Saleem Wani
Journal of Solid Tumors , 2012, DOI: 10.5430/jst.v2n4p57
Abstract: The discovery and utilization of tumor markers have affected early detection, diagnosis, and staging and follow up of Prostate cancer and have improved curative rates. The goal of identifying different tumor markers in prostate cancer is to get the early diagnosis. One can also see the effect of treatment modality used and prognosticate the disease. In this review we intend to give a detailed account of different markers in prostate cancer. Besides Prostate Specific Antigen, Human kallikrein 2, Kallikrein-related peptidase 14, Prostate acid phosphatase, Cancer Antigen 15-3, Prostate-specific membrane antigen etc. are discussed in detail.
Pleuropulmonary blastoma in a 3-year-old male child with recurrence in less than two months time
Reyaz Ahmad Lone,Mohd Lateef Wani,Shadab Nabi Wani,Abdul Gani Ahangar
Chest Disease Reports , 2012, DOI: 10.4081/cdr.2012.e9
Abstract: Pleuropulmonary blastoma is a rare childhood neoplasm accounting for less than one percent of all primary malignant lung tumours of children less than six years of age. Meta - stasis to central nervous system, orbit and iris, bone, contralateral lung and rarely adrenalglands, liver, kidney and pancreas has been described. We present a case of pleuropulmonary blastoma in a 3-year-old child who had a recurrence in less than three months, after surgical resection.
Primary Pelvic Hydatid Cyst: A Case Report
Fazl Q. Parray,Shadab Nabi Wani,Sajid Bazaz,Shakeel-ur Rehman Khan,Nighat Shaffi Malik
Case Reports in Surgery , 2011, DOI: 10.1155/2011/809387
Abstract: This is a case report of a young man who presented to us as a case of hypogastric pain and frequency of micturation. General physical examination and radiological evaluation confirmed a multiloculated pelvic swelling. Patient was subjected to laparotomy which confirmed the diagnosis of a primary pelvic hydatid disease. Patient was put on chemotherapy after surgery and is doing well on follow up.
Primary calcified hydatid of spleen: a case report
Dr. Imtiaz Wani,Dr. Shadab Wani,Dr. Aejaz Baba,Dr. Zaffar Khanday
Internet Journal of Medical Update - EJOURNAL , 2010,
Abstract: Most splenic cysts are parasitic. Hydatid disease, a parasitic disease, is endemic in Kashmir. Splenic involvement alone in hydatid disease is very rare. It may remain asymptomatic or, by causing pressure due to increasing size on adjacent viscera, may become symptomatic. A non specific presentation always makes diagnosis difficult. A case of hydatid spleen in a young boy who presented with abdominal pain is reported. Radiology complemented with serology made the diagnosis. Hydatid disease should be considered as a differential diagnosis in every patient with a calcified cystic mass of the spleen in endemic areas.
Encountering Meckel's diverticulum in emergency surgery for ascaridial intestinal obstruction
Imtiaz Wani, Viliam ?nábel, Ghulam Naikoo, Shadab Wani, Muddasir Wani, Abid Amin, Tariq Sheikh, Fazal Q Parray, Rauf A Wani
World Journal of Emergency Surgery , 2010, DOI: 10.1186/1749-7922-5-15
Abstract: A retrospective case review study of 14 children who had surgical intervention for symptomatic intestinal ascariasis having the presence of concomitant Meckel's diverticulum was done. The study was done at SMHS Hospital Srinagar, Kashmir.A total of the 14 children who had ascaridial intestinal obstruction with concomitant presence of Meckel's diverticulum were studied. Age of children ranged from 4-12 years, male:female ratio was 1.8:1. Nine patients had asymptomatic Meckel's diverticulum, whereas 5 patients with symptomatic signs were found in the course of emergency surgery for ascaridial intestinal obstruction.Meckel's diverticulum in intestinal ascariasis may pursue silent course or may be accompanied with complications of the diverticulitis, perforation or the gangrene. Incidental finding of the Meckel's diverticulum in the intestinal ascariasis should have removal.Though ascaris infestation is usually asymptomatic, ascariasis-related intestinal complications can be seen children with a high intestinal roundworm load. Presence of massive roundworm infestation in children may lead to symptomatic Meckel's diverticulum. High burden of intestinal roundworms, propensity to wander, size of the worm and the characteristics of Meckel's diverticulum constitute prerequisite for complications of Meckel's diverticulum. Surgical complications associated with Ascaris lumbricoides infection can be diverticulitis, gangrene or the perforation in the Meckel's diverticulum. Preoperative diagnosis of Meckel's diverticulum is often difficult. Incidental diverticulectomies in asymptomatic Meckel's diverticulum are considered safer [1,2]. The work was designed to study findings of concomitant Meckel's diverticulum who had surgical intervention for ascaridial intestinal obstruction in children.A retrospective case review study of 14 children who had surgical intervention for symptomatic ascaridial intestinal obstruction with the presence of the concomitant Meckel's diverticulum, was d
Nanotoxicity: Dimensional and Morphological Concerns
Mohmmad Younus Wani,Mohd Ali Hashim,Firdosa Nabi,Maqsood Ahmad Malik
Advances in Physical Chemistry , 2011, DOI: 10.1155/2011/450912
Abstract: Nanotechnology deals with the construction of new materials, devices, and different technological systems with a wide range of potential applications at the atomic and molecular level. Nanomaterials have attracted great attention for numerous applications in chemical, biological, and industrial world because of their fascinating physicochemical properties. Nanomaterials and nanodevices are being produced intentionally, unintentionally, and manufactured or engineered by different methods and released into the environment without any safety test. Nantoxicity has become the subject of concern in nanoscience and nanotechnology because of the increasing toxic effects of nanomaterials on the living organisms. Nanomaterials can move freely as compared to the large-sized particles; therefore, they can be more toxic than bulky materials. This review article delineates the toxic effects of different types of nanomaterials on the living organisms through different sources, like water, air, contact with skin, and the methods of determinations of these toxic effects. 1. Introduction Hundreds of researchers all over the world are engaged in delving deep into the field of nanotechnology. Nanoscience and nanotechnology promise for creating new materials with enhanced properties and potential applications [1, 2]. The properties of these various types of intentionally produced nanomaterials and nanoparticles enable potential application in commercial, medical, environmental sectors and so forth. Nanoparticles are said to be central to many natural processes [3–5]. Nanoparticles are present in the environment from both natural and anthropogenic sources. Examples of natural nanoparticles include volcanic ash, ocean spray, and mineral composites. Anthropogenic nanoparticles can be either incidental or engineered. Manufactured or engineered nanoparticles have great diversity in shape and function as seen in large variety of carbon nanotubes, fullerenes, polymers, nanoribbons and dendrimers. Many nanoparticles have unique properties, such as being optically transparent and distinctive surface properties. Many concerns have risen regarding the disruption of many critical biological processes by many engineered nanomaterials. Various nanomaterials have proven to be toxic to humans, animals, and environmental systems [6]. Yet nanomaterials are being manufactured commercially and released into the environment without any health and safety testing or environmental impact assessment. Despite this lack of oversight, there are hundreds of products [7–9] containing nanomaterials that
Vascular Injuries Caused by Tear Gas Shells: Surgical Challenge and Outcome
Mohd Lateef Wani,Ab Gani Ahanga,Gh Nabi Lone,Shyam Singh
Iranian Journal of Medical Sciences , 2011,
Abstract: Background: Tear gas shells are used to disperse the mob during any type of street protests. Vascular injuries due to tear gas shells have not been reported. The present study was un-dertaken to analyse the pattern, presentation, management and outcome of vascular injury due to tear gas shells. Methods: Eighteen patients with vascular injury caused by tear gas shells from 1st Jan. 2008 to 31st Dec 2009 were studied. Patients with vascular injuries caused by causes other than tear gas shells were excluded from the study. Results: All patients were treated with reverse saphenous vein graft as segmental loss was less than 2.5 cm. Wound infection was the most common complication, followed by graft occlusion. Amputation rate was 16.66%. Associated nerve injury occurred in 44.44% of the patients. Conclusion: Tear gas shell injuries should not be taken lightly. They can cause injuries as serious as vascular injuries. Vascular injuries cased by tear gas shells require prompt revascularisation to improve limb salvage. De-spite proper revascularisation, patients have significant morbidity and need proper rehabilitation in the follow ups.
Delayed Presentation of Traumatic Diaphragmatic Hernia: a Diagnosis of Suspicion with Increased Morbidity and Mortality
Farooq Ahmad Ganie,Hafeezulla Lone,Ghulam Nabi Lone,Mohd Lateef Wani
Trauma Monthly , 2013, DOI: 10.5812/traumamon.7125
Abstract: Background: Diaphragmatic rupture due to blunt or penetrating injury may be a missed diagnosis in an acute setting and can present with a delayed complication with significantly increased morbidity and mortality.Objectives: The objective of this study is to better understand why diaphragmatic tears with delayed presentation and diagnosis are so often missed and why traumatic diaphragmatic tears are difficult to diagnose in emergency settings and how they present with grievous complications.Patients and Methods: Eleven patients with diaphragmatic hernias with delayed presentation and delayed diagnosis were operated within the last five years. All patients presented with different complications like gut gangrene or respiratory distress.Results: Out of eleven patients who were operated on for diaphragmatic hernia, three patients (27%) died. Three patients required colonic resection, one patient needed gastrectomy and one patient underwent esophagogastrectomy.Conclusions: A small diaphragmatic tear due to blunt trauma to the abdomen is difficult to diagnosis in acute settings due to ragged margins and possibly no herniated contents and usually present with a delayed complication. Therefore a careful examination of the entire traumatized area is the best approach in treating delayed presentation of traumatic diaphragmatic hernia prior to development of grievous complications.
REE Characteristics and REE Mixing Modeling of the Proterozoic Quartzites and Sandstones  [PDF]
H. Wani
International Journal of Geosciences (IJG) , 2017, DOI: 10.4236/ijg.2017.81002
Abstract: Rare earth elements (REE) in sedimentary rocks are most suitable for source rock characterization. Rare earth element data of the sandstones of the unmetamorphosed Meso-Neoproterozoic Chhattisgarh and Indravati basins and the metamorphosed Paleoproterozoic Sakoli and Saucer basins of the Bastar craton have been studied for source rock characterization. The quartzites have higher ∑R EE mean value (145 ppm) compared to the sandstones (34 ppm). The REE patterns of all the three formations of the Chandarpur Group of the Chhattisgarh basin and the Tiratgarh Formation of the Indravati basin are uniform and there are no systematic differences in REE patterns among different formations of the Chandarpur Group and the Tiratgarh Formation. The REE patterns of the quartzites are similar to the REE patterns of the sandstones. Chondrite-normalized REE patterns with LREE enrichment and a strong negative Eu anomaly of the sandstones and quartzites gives a broad hint about felsic source rocks. The source rocks are identified as Archean granite and gneiss of the Bastar craton. The REE mixing modeling of the sandstones and quartzites suggest that the exposed the Proterozoic upper crust of the Bastar craton during the sedimentation of the Paleoproterozoic Sakoli and saucerand the Meso-Neoproterozoic Chhattisgarh and Indravati basins of the Bastar craton was largely consisted of gneissic rocks (70%), with a little contribution (20%) from Late Archean (2.5 Ga) granites. The present study does not suggest any significant change in the upper crustal composition during Proterozoic in the Bastar craton.
Iranian Journal of Child Neurology , 2012,
Abstract: -
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