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Search Results: 1 - 10 of 3065 matches for " Seyed Ebrahim Eskandari "
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Comparison of efficacy of intralesional injection of meglumine anti-moniate once-weekly with twice-weekly in the treatment of anthroponotic cutaneous leishmaniasis in Mashhad: a randomized clinical trial
Ali Khamesipour,Mohammad Hossein Ghoorchi,Alireza Khatami,Seyed Ebrahim Eskandari
Dermatology and Cosmetic , 2011,
Abstract: Background and Aim: Cutaneous leishmaniasis (CL) is endemic in Iran, where it is one of the most important health problems. Both anthroponotic CL (ACL) caused by L. tropica and zoonotic CL (ZCL) caused by L. major are reported. Antimoniate derivatives as the standard therapy for CL need multiple injections and are not easy to tolerate for the patients. This study was conducted in Mashhad to compare the efficacy of weekly versus twice a week intralesional injections of meglumine antimoniate (MA) in the treatment of ACL."n"nMethods: This randomised controlled trial was performed during 2006 to 2008 in Mashhad, Iran. Using computerized sequence of random numbers, participants were randomly allocated in the two arms of the study: one receiving weekly and the other receiving twice-a-week intralesional injections of MA. The lesion size, induration and healing rate were assessed, recorded and compared. Healing was defined as complete re-epithelialisation and disappearance of induration."n"nResults: A total of 252 suspected CL patients with 372 lesions were screened. 82 parasitologically proven cases with 121 lesions caused by L. tropica were included and 74 patients with 113 lesions completed the study. At 12th week after initiation of treatment, complete healing was observed in 38 out of 44 lesions (86.4%) in the group which received weekly intralesional MA injection. The median time-to-heal in this group was 36 days (95% confidence interval [CI]: 32.0-39.9). Complete healing was recorded in 60 out of 69 lesions (86.9%) in the group which received twice a week intralesional injections of MA with a median time-to-heal of 25 days (95% CI: 20.9-29.1). While no significant difference was observed between the two groups in terms of complete healing rate (P=0.999), time-to-heal was significantly different between the 2 groups (P=0.003)."n"nConclusion: It seems that the effectiveness of twice-weekly intralesional injections of MA is similar to once-weekly regimen while the former regimen causes more rapid healing of lesions.
Male Breast Cancer Clinical Features, Risk Factors, and Current Diagnostic and Therapeutic Approaches  [PDF]
Mojgan Haji Seyed Ebrahim Darkeh, Edward Azavedo
International Journal of Clinical Medicine (IJCM) , 2014, DOI: 10.4236/ijcm.2014.517138
Abstract: Objective: To review presentation, diagnosis, treatment and prognosis of male breast cancer. Method: A systematic review of the English language literature between 1990 and 2013 was conducted to identify studies relevant to the objective. Searches were carried out on the database PubMed, by using the title term “male breast cancer”. Results: The majority of male patients present with a painless, firm, subareolar lump. Experience of male breast imaging is good but limited. However, there is no definitive therapeutic algorithm. Men are often treated with mastectomy instead of breast conserving surgery and mostly tamoxifen is used as an adjuvant therapy. The most important prognostic factors are tumor size and lymph node status in the armpit. Conclusion: More increased awareness and further research are needed to improve the diagnosis and treatment of this disease.
Simple excision alone versus simple excision plus mitomycin C in the treatment of pterygium
Mikaniki Ebrahim,Rasolinejad Seyed
Annals of Saudi Medicine , 2007,
Abstract: Background: Pterygium is a common ocular disorder throughout the world. The purpose of this study was to evaluate the efficacy of simple excision alone with or without topical mitomycin in the treatment of pterygium. Patients and Methods: This study was performed in two stages. In the first stage, from 1991 to 1994, 100 patients (group 1) were operated on with simple excision and in the second stage, from 1995 to 1999, 300 patients (group 2) were treated with the same procedure plus topical mitomycin (0.02% eye drops four times a day for 4 days after operation). All cases were followed for 5 years. The recurrence rate of pterygium in these two treated groups were groups were compared. Results: The mean age of the subjects was 49±13 years in group 1 and 47±17 years in group 2. The clinical manifestations in these two groups were two groups were similar (P>0.05). After one year, relapse was seen in 21 cases (21%) in group 1 and in 3 cases (1%) in group 2. After five years, 31 cases (31%) in group 1 and 3 cases (1%) in group 2 had relapse (P=0.0001). The mean time to recurrence at five years for the simple excision group was 3.83 years (95% CI: 3.48 to 4.17 years) and for simple excision plus mitomycin C was 4.96 years (95% CI: 4.91 to 5.0 years) (P< 0.0001). Conclusion: Instillation of mitomycin C eye drops appears to be safe in the treatment of pterygium.
ANALYSIS OF THE ESSENTIAL OILS OF TWO CULTIVATED BASIL (OCIMUM BASILICUM L.) FROM IRAN
SEYED EBRAHIM SAJJADI
DARU : Journal of Pharmaceutical Sciences , 2006,
Abstract: The chemical compositions of the essential oils of Ocimum basilicum L. cv. purple and Ocimum basilicum L. cv. green cultivated in Iran were investigated by GC-MS. Twenty constituents (98.5% of the total oil) were identified in the volatile oil of O. basilicum L. cv. Purple. The main constituents found in the oil were methyl chavicol (52.4%), linalool (20.1%), epi- -cadinol (5.9%) and trans- -bergamotene (5.2%). In the volatile oil of O. basilicum L. cv. green, twelve components were characterized representing 99.4% of the total oil. Methyl chavicol (40.5%), geranial (27.6%), neral (18.5%) and caryophyllene oxide (5.4%) were the major components. Methyl chavicol is the dominant constituent in each of the two oils. Although the oil of green basil was characterized by a highccontent (46.1%) of citral (neral and geranial), citral was not detected in the oil of purple basil oil.
ANALYSIS OF THE ESSENTIAL OIL OF NEPETA SINTENISII BORNM. FROM IRAN
SEYED EBRAHIM SAJJADI
DARU : Journal of Pharmaceutical Sciences , 2005,
Abstract: Nepeta is a one of the most important genera of the Lamiaceae family with regard to the number of species. Some species of this genus are important medicinal plants and their extracts have been used for medicinal purposes. In this investigation aerial parts of Nepeta sintenisii Bornm. was subjected to hydrodistillation and the chemical composition of the isolated essential oil was analyzed by GC/MS method for first time. Forty constituents (96.5% of the total oil) were identified of which 4aβ,7α,7aβ-nepetalactone (23.4%), elemol (16.1%), E-β-farnesene (9.5%), 1,8-cineole (8.2%), cis-sabinene hydrate (6.5%), β-bisabolene (4.2%) and germacrene-D (3.5%) were the main components. The constituents of the volatile oil of N. sintenisii is similar to the composition of the other Nepeta genus.
Phenotypic and Molecular Characterization of Wheat Leaf Rust Resistance Gene Lr34 in Iranian Wheat Cultivars and Advanced Lines  [PDF]
Seyed Taha Dadrezaei, Kumarse Nazari, Farzad Afshari, Ebrahim Mohammadi Goltapeh
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.49224
Abstract:

Lr34 is a vital gene in developing resistance to leaf rust, stripe rust, and powdery mildew of wheat. Providing simultaneous resistance to various pathogens has made this gene valuable in breeding for wheat resistance to many diseases. The present study investigates the csLV34 marker’s capability in diagnosing this locus in130 wheat commercial cultivars and advanced wheat lines from Iran, and assesses the impact of this gene on disease severity in field conditions. To assess the reactions of cultivars and lines which contained Lr34 under epidemic conditions of leaf rust, these cultivars were cultivated during the 2009 and 2010 cropping season. Of the 130 studied cultivars, 43 contained Lr34. Cultivars that were selected and studied in stress conditions had the most frequent presence of Lr34. It can be concluded that this gene plays a vital role in increasing the tolerance of cultivars under stress conditions. Lr34 seems to cause active

Circumcision Complications Associated with the Plastibell Device and Conventional Dissection Surgery: A Trial of 586 Infants of Ages up to 12 Months
Seyed Abdollah Mousavi,Ebrahim Salehifar
Advances in Urology , 2008, DOI: 10.1155/2008/606123
Abstract: Conventional dissection surgery (CDS) or using the Plastibell device (PD) is the method most frequently employed for circumcision. The aim of this study was to evaluate two methods in terms of the incidence of complications in infants of ages up to 12 months. In a prospective study, 586 infants equal to or less than 12 months were studied from 2002 to 2008, and complications between the two groups were assessed. The overall rates of complications in CDS and PD groups were 1.95% and 7.08%, respectively. In each group, the rate of complications was not different among children who had a normal weight, compared to those of a lower or upper (10%) weight. There was a significant positive correlation between the age and weight of subjects within the time of ring separation (<.001). The results of this study suggest the PD method for neonates and low-weight infants with thin prepuce and the CDS for other infants.
Comparative Evaluation of Intraocular Pressure and Hemodynamic Changes During Tracheal Intubation and Extubation
Ebrahim Nasiri,Seyed Jalal Hosseinimehr
Research Journal of Biological Sciences , 2012,
Abstract: Intraocular Pressure (IOP) may increase during general anesthesia due to intubation. Increasing of IOP in some surgical procedures may lead to complications and it is important to reduce IOP. The changes of the IOP and haemodynamic variable are evaluated during intubation and extubation at the end of general anesthesia. In this study, 51 patients were selected for orthopedic and general surgery. A standard general anaesthesia was treated to all of the patients. For maintaining airway during anesthesia, the patients were received directly laryngoscopy intubing technique. Intraocular pressure was measured at different stages prior to intubation and extubation and then at 1, 5 and 10 min after intubation and extubation with shiutze tonometer by a trained and expert person. The Blood Pressure (BP) and Heart Rate (HR) were measured. Results show that tracheal intubation and extubation cause increase in IOP at 1, 5 min after intubation. The highest increase in IOP level occurs one minute after extubation (43.41%). It was not significantly between increasing in IOP during above mentioned extubaion period. Intubation and extubation caused increase BP and heart rate. The highest increase in BP and heart rate happens at the first minute after intubation (30.63, 14.86%). It statistically was difference between increasing in the BP and HR during intubation and extubation (p< 0.05). Although IOP level was significantly increased but it was normal range. With the regards to increase in IOP level during extubation compare to intubation at prior and 1 min after intubation, it is recommended that the more accurate planning to prevent increasing of above-mentioned changes at the time of intubation.
The Effect of Halothane on SGOT and SGPT of Operating Room Personnel
Ebrahim Nasiri,Seyed Jalal Hosseinimehr
Pakistan Journal of Biological Sciences , 2006,
Abstract: In this study, liver damage induced by occupational exposure of the anesthetic agent to operating room staff was investigated. A total of 70 persons who employed with more than one year in operation room were investigated. Controls were 70 personnel of the same hospitals with similar conditions who were not working in operation room. Serum levels of alanine aminotransferase (SGPT) and aspartate aminotransferase (SGOT) were measured. Serum SGOT activity was significantly increased in the anesthesiology staff compared to controls. But elevated SGPT in cases was no significant compared to non-exposure group. In this study, although raised aminotransferases enzymes were observed in anesthesiology staff but the serum activity of these enzymes were in the normal range and not observed any abnormality in SGOT and SGPT in staff employed in the operation room. In order to take more care of personnel-health, air concentration of anesthetic gases should be kept as low as possible by help of sufficient room ventilation avoiding unnecessary emissions.
Comparative Evaluation of Intraocular Pressure and Hemodynamic Changes During Tracheal Intubation and Extubation
Ebrahim Nasiri,Seyed Jalal Hosseinimehr
Research Journal of Biological Sciences , 2007,
Abstract: Intraocular Pressure (IOP) may increase during general anesthesia due to intubation. Increasing of IOP in some surgical procedures may lead to complications and it is important to reduce IOP. The changes of the IOP and haemodynamic variable are evaluated during intubation and extubation at the end of general anesthesia. In this study, 51 patients were selected for orthopedic and general surgery. A standard general anaesthesia was treated to all of the patients. For maintaining airway during anesthesia, the patients were received directly laryngoscopy intubing technique. Intraocular pressure was measured at different stages prior to intubation and extubation and then at 1, 5 and 10 min after intubation and extubation with shiutze tonometer by a trained and expert person. The Blood Pressure (BP) and Heart Rate (HR) were measured. Results show that tracheal intubation and extubation cause increase in IOP at 1, 5 min after intubation. The highest increase in IOP level occurs one minute after extubation (43.41%). It was not significantly between increasing in IOP during above mentioned extubaion period. Intubation and extubation caused increase BP and heart rate. The highest increase in BP and heart rate happens at the first minute after intubation (30.63, 14.86%). It statistically was difference between increasing in the BP and HR during intubation and extubation (p< 0.05). Although IOP level was significantly increased but it was normal range. With the regards to increase in IOP level during extubation compare to intubation at prior and 1 min after intubation, it is recommended that the more accurate planning to prevent increasing of above-mentioned changes at the time of intubation.
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