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Search Results: 1 - 10 of 463589 matches for " Seth A Hoffman "
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Female Anopheles gambiae antennae: increased transcript accumulation of the mosquito-specific odorant-binding-protein OBP2
Seth A Hoffman, Lakshminarayanan Aravind, Soundarapandian Velmurugan
Parasites & Vectors , 2012, DOI: 10.1186/1756-3305-5-27
Abstract: Our initial focus is on odorant binding proteins with differential transcript accumulation between female and male mosquitoes. We report that the odorant binding protein, OBP2 (AGAP003306), had increased expression in the antennae of female vs. male Anopheles gambiae sensu stricto (G3 strain). The increased expression in antennae of females of this gene by quantitative RT-PCR was 4.2 to 32.3 fold in three independent biological replicates and two technical replicate experiments using A. gambiae from two different laboratories. OBP2 is a member of the vast OBP superfamily of insect odorant binding proteins and belongs to the predominantly dipteran clade that includes the Culex oviposition kairomone-binding OBP1. Phylogenetic analysis indicates that its orthologs are present across culicid mosquitoes and are likely to play a conserved role in recognizing a molecule that might be critical for female behavior.OBP2 has increased mRNA transcript accumulation in the antennae of female as compared to male A. gambiae. This molecule and related molecules may play an important role in female mosquito feeding and breeding behavior. This finding may be a step toward providing a foundation for understanding mosquito olfactory requirements and developing control strategies based on reducing mosquito feeding and breeding success.Factors that influence mosquito fitness, especially host seeking and mate finding are complex and modulated by multiple cues, of which olfactory cues are most important [1-4]. Detection of odor molecules requires odorant binding proteins (OBPs) that are abundant in antennal chemosensilla [5,6]. OBPs are low molecular weight soluble proteins that bind and transport odor molecules from sensillae to G-protein-coupled receptors in olfactory sensory neurons [6]. The finding of receptor AgamOBP1 binding to its ligand indole demonstrated the significance of OBPs in odor recognition [7]. Understanding olfactory function could lead to development of malaria control
“-group congruences on regular “-semigroups
A. Seth
International Journal of Mathematics and Mathematical Sciences , 1992, DOI: 10.1155/s0161171292000115
Abstract: In this paper a “-group congruence on a regular “-semigroup is defined, some equivalent expressions for any “-group congruence on a regular “-semigroup and those for the least “-group congruence in particular are given.
Emergent Literacy: Children's Books from 0 to 3 edited by Bettina Kümmerling-Meibauer: Amsterdam & Philadelphia: John Benjamins Publishing, 2011. ISBN: 978-9027218087
A. Robin Hoffman
Barnboken : Tidskrift f?r Barnlitteraturforskning , 2013, DOI: 10.3402/clr.v36i0.20659
Successful Application of Active Learning Techniques to Introductory Microbiology
Elizabeth A. Hoffman
Journal of Microbiology & Biology Education , 2001, DOI: 10.1128/jmbe.v2i1.58
Abstract: While the traditional lecture format may be a successful way to teach microbiology to both medical and nursing students, it was not an effective means of learning for many prenursing and preprofessional students enrolled in either of the introductory microbiology courses at Ashland Community College, an open enrollment institution. The structure of both Medical Microbiology and Principles of Microbiology was redesigned to allow students to address the material in an active manner. Daily quizzes, student group discussions, scrapbooks, lab project presentations and papers, and extra credit projects were all added in order to allow students maximum exposure to the course material in a manner compatible with various methods of learning. Student knowledge, course evaluations, and student success rates have all improved with the active learning format.
Adding handles to the helicoid
David A. Hoffman
Mathematics , 1993,
Abstract: There exist two new embedded minimal surfaces, asymptotic to the helicoid. One is periodic, with quotient (by orientation-preserving translations) of genus one. The other is nonperiodic of genus one.
A one-step electrospray-based technique for modulating morphology and surface properties of poly(lactide-co-glycolide) microparticles using Pluronics
Seth A, Katti DS
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S34185
Abstract: one-step electrospray-based technique for modulating morphology and surface properties of poly(lactide-co-glycolide) microparticles using Pluronics Rapid Communication (1502) Total Article Views Authors: Seth A, Katti DS Published Date September 2012 Volume 2012:7 Pages 5129 - 5136 DOI: http://dx.doi.org/10.2147/IJN.S34185 Received: 24 May 2012 Accepted: 12 July 2012 Published: 26 September 2012 Anushree Seth, Dhirendra S Katti Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India Abstract: The influence of morphology and surface properties on the therapeutic efficacy of degradable polymeric microparticles has not been well understood. One of the primary reasons for this is the limited ability to fabricate microparticles with controlled morphology and surface properties. Here, we report the electrospraying of blends of Pluronic with poly(lactide-co-glycolide) (PLGA) as a novel, one-step approach for the simultaneous modulation of morphology and surface properties of PLGA microparticles. Blending with Pluronic altered the morphology from doughnut-shaped to smooth, spherical-shaped microparticles, and variation in the type of Pluronic systematically modulated the surface properties of the microparticles. Hence, blending with Pluronic can be a facile technique for the modulation of morphology and surface properties of electrosprayed PLGA microparticles.
Strategic Asymmetric Deception and Its Role in the Current Threat Environment
Seth A. Gulsby
Journal of Strategic Security , 2010,
Abstract: President Bill Clinton's Secretary of Defense, William Cohen, once stated that the post-Cold War world of the 1990s was a "paradox [where] American military superiority actually increase[d] the threat of... attack against [the U.S.] by creating incentives for adversaries to challenge us asymmetrically." He was alluding to the fact that the Cold War's closure was supposed to bring about a situation that encouraged peace, nation-building, and unilateral comfort for the United States. The reality that America has come to know is quite different, and some might even argue that, given the option, many people would return to a security situation comparable to the bipolar world of the Cold War.
Shape in an Atom of Space: Exploring quantum geometry phenomenology
Seth A. Major
Physics , 2010, DOI: 10.1088/0264-9381/27/22/225012
Abstract: A phenomenology for the deep spatial geometry of loop quantum gravity is introduced. In the context of a simple model, an atom of space, it is shown how purely combinatorial structures can affect observations. The angle operator is used to develop a model of angular corrections to local, continuum flat-space 3-geometries. The physical effects involve neither breaking of local Lorentz invariance nor Planck scale suppression, but rather reply on only the combinatorics of SU(2) recoupling. Bhabha scattering is discussed as an example of how the effects might be observationally accessible.
Embedded graph invariants in Chern-Simons theory
Seth A. Major
Physics , 1998, DOI: 10.1016/S0550-3213(99)00164-9
Abstract: Chern-Simons gauge theory, since its inception as a topological quantum field theory, has proved to be a rich source of understanding for knot invariants. In this work the theory is used to explore the definition of the expectation value of a network of Wilson lines - an embedded graph invariant. Using a slight generalization of the variational method, lowest-order results for invariants for arbitrary valence graphs are derived; gauge invariant operators are introduced; and some higher order results are found. The method used here provides a Vassiliev-type definition of graph invariants which depend on both the embedding of the graph and the group structure of the gauge theory. It is found that one need not frame individual vertices. Though, without a global projection of the graph, there is an ambiguity in the relation of the decomposition of distinct vertices. It is suggested that framing may be seen as arising from this ambiguity - as a way of relating frames at distinct vertices.
Small asteroid system evolution
Seth A. Jacobson
Physics , 2014, DOI: 10.1017/S174392131400800X
Abstract: Observations with radar, photometric and direct imaging techniques have discovered that multiple asteroid systems can be divided clearly into a handful of different morphologies, and recently, the discovery of small unbound asteroid systems called asteroid pairs have revolutionized the study of small asteroid systems. Simultaneously, new theoretical advances have demonstrated that solar radiation dictates the evolution of small asteroids with strong implications for asteroid internal structure. We review our current understanding of how small asteroid systems evolve and point to the future.
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