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Search Results: 1 - 10 of 757 matches for " Serkan ?ncü "
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Cerebrospinal Fluid Shunt Infections
Klimik Journal , 2010,
Abstract: Shunt is the most common approach among medical and surgical treatment modalities for treating hydrocephalus. The main purpose of the shunt is to reduce intracranial pressure by draining the cerebrospinal fluid (CSF) from the ventricles. Infection is one of the serious complications and it develops in approximately 5-15% of the inserted devices. The microorganisms responsible for the shunt infection usually arise from the normal flora of the skin. During the surgical procedure and healing period, microorganisms residing in skin may adhere to the shunt and start the infection. The clinical symptoms may differ according to the type of shunt used. Abdominal pain is the most common complaint in patients with infected ventriculo-peritoneal (VP) shunt. On the other hand, fever is the leading symptom in ventriculo-atrial (VA) shunt infection. Other than clinical signs, biochemical and microbiological analysis of CSF are necessary to diagnose shunt infection. The gold standard of treatment is the usage of antibiotics with shunt revision. In addition to parenteral antibiotics, intraventricular administration of antibiotics may be an essential part of the treatment. The most efficient way to avoid shunt infection is to follow the strict rules for preventing surgical site infections.
Neutropenic Enterocolitis
Klimik Journal , 2009,
Abstract: Neutropenic enterocolitis, which has very high mortality, is one of the syndromes that may develop in immunocompromised patients. This syndrome usually develops after the usage of cytotoxic drugs and the main symptoms are fever and abdominal pain. Other than aerobic and anaerobic inhabitant bacteria of the intestine, fungi may also be the etiologic agent in this syndrome. Clinical findings, ultrasound and computed tomography are used for diagnosis. Caecum is the most involved intestinal segment and the wall thickness greater than 4 mm should be interpreted as diagnostic sign. Supporting therapy and broad spectrum antibiotics that covers possible pathogens should be started for neutropenic enterocolitis. Surgery should be considered in patients with clinical deterioration, perforation and uncontrolled hemorrhage.
Advanced Age and Mild Thyrotoxicosis are Associated with Nodular Goiter in Graves Disease
Serkan Yener,Nergiz Bayrak??,Bar?? Ak?nc,Tevfik Demir
Turkish Journal of Endocrinology and Metabolism , 2009,
Abstract: Objective: The primary goal of this study is to evaluate predictors of nodular goiter in Graves Disease (GD).Materials and Methods: A total of 202 consecutive patients (mean age: 45; 145 female, 57 male) were enrolled. All patients were treated with antithyroid drugs as initial therapy. TSH, FT3, FT4, TRAb, ATPO, and ATG were measured. Radioactive iodine uptake and thyroid ultrasonography were performed, and thyroid volume and nodule diameter were assessed. Ultrasound-guided fine needle aspiration was performed on thyroid nodules ≥8mm. Results: Diffuse goiter was detected in 51% of patients. Solitary nodules were detected in 16%, and multi-nodular disease in 33%. Mean nodule diameter was 8.82 mm. Nodular disease was slightly more common in women (p=0.063). Patients with nodular GD were older (p=0.004), had lower levels of FT3 (p=0.016) and TRAB (p=0.002) when compared with subjects with diffuse GD. Age (OR:6.867) was the independent variable predicting nodular GD. Conclusion: Increased prevalence of nodules was associated with advanced age and milder thyrotoxicosis. Apoptosis of thyroid follicular cells due to excess iodine might interfere with nodule formation, and lead to diffuse goiter in severe thyrotoxicosis. Because of increased rate if malignancy in GD, comprehensive evaluation of thyroid nodules of any size is mandatory. Turk Jem 2009; 13: 1-4
Central venous catheter related infections: Risk factors and the effect of glycopeptide antibiotics
Serkanncü, Halit ?zsüt, Ay?e Yildirim, Pinar Ay, Nahit ?akar, Haluk Eraksoy, Semra ?alangu
Annals of Clinical Microbiology and Antimicrobials , 2003, DOI: 10.1186/1476-0711-2-3
Abstract: During the study period 300 patients with central venous catheters were prospectively studied. The catheters used were nontunneled, noncuffed, triple lumen and made of polyurethane material. Catheters were cultured by semiquantitative method and blood cultures done when indicated. Data were obtained on patient age, gender, unit, primary diagnosis on admission, catheter insertion site, duration of catheterization, whether it was the first or a subsequent catheter and glycopeptide antibiotic usage.Ninety-one (30.3%) of the catheters were colonized and infection was found with 50 (16.7%) catheters. Infection was diagnosed with higher rate in catheters inserted via jugular vein in comparison with subclavian vein (95% CI: 1.32–4.81, p = 0.005). The incidence of infection was higher in catheters which were kept in place for more than seven days (95% CI 1.05–3.87, p = 0.03). The incidence of infection was lower in patients who were using glycopeptide antibiotic during catheterization (95% CI: 1.49–5.51, p = 0.005). The rate of infection with Gram positive cocci was significantly lower in glycopeptide antibiotic using patients (p = 0.01). The most commonly isolated organism was Staphylococcus aureus (n = 52, 37.1%).Duration of catheterization and catheter insertion site were independent risk factors for catheter related infection. Use of glycopeptide antibiotic during catheterization seems to have protective effect against catheter related infection.Central venous catheters (CVCs) are widely used in critically ill patients throughout the developed world. They permit hemodynamic monitoring and allow access for the administration of fluids, blood products, medications, and total parenteral nutrition (TPN). Estimates of their use in the United States alone suggest that over five million CVCs are inserted annually [1,2]. Although CVCs have significant benefits in many clinical situations, the increase in their use over the last 20 years has been associated with at least a doubl
An Adult Case of Diabetic Ketoacidosis Presenting with Cerebral Edema
Bar?? Ak?nc,Abdurrahman ??mlek?i,Serkan Yener,Süleyman Men
Turkish Journal of Endocrinology and Metabolism , 2009,
Abstract: Cerebral edema is a life-threatening complication of diabetic ketoacidosis (DKA) which may predominantly develop in pediatric cases during the management of DKA.. Symptomatic cerebral edema in children is rarely detected at admission, before initiation of the treatment. Cerebral edema associated with DKA is extremely rare in adults. Here, we report an adult patient with DKA who presented with symptomatic cerebral edema. Turk Jem 2009; 13: 16-8
Use of Metformin in Pregnancy: A Survey of Turkish Physicians’ Attitudes
Bar?? Ak?nc,P?nar Tosun,Emine Bek?i,Serkan Yener
Turkish Journal of Endocrinology and Metabolism , 2009,
Abstract: Objective: Although metformin crosses the placenta, there is no current evidence whether the use of metformin in pregnancy is associated with increased risk of fetal and maternal complications. The aim of this present study is to investigate the attitudes of Turkish physicians in different specialties in terms of metformin use in pregnancy. Materials and Methods: Current opinions were assessed by a questionnaire. Nine hundred forty physicians were invited to join the study; however, completely fulfilled questionnaires could be obtained from a total of 407 physicians (170 family physicians, 139 internists and 98 obstetricians).Results: One hundred fifty-one physicians (37.1%) stated that they recommended metformin use in pregnancy for any of the indications (pregnant women with PCOS, type-2 diabetes or gestational diabetes). Obstetricians were more likely to suggest metformin use in pregnancy rather than other physicians. Metformin use in pregnancy was seldom recommended by internists. The rationales of physicians for the metformin use were: lower risk for abortion, decreased prevalence of maternal and neonatal complications, improvement in insulin resistance, prevention of excess weight gain, better glycemic control in diabetics and decreased insulin need in diabetics taking insulin. Conclusions: Despite limited data on metformin use in pregnancy, significant number of physicians in Turkey supported the metformin use. Obstetricians were the ones most likely to recommend metformin treatment in pregnancy. Turk Jem 2009; 13: 25-8
Software Competences of Geomatic Engineering  [PDF]
Serkan Aydin
International Journal of Geosciences (IJG) , 2015, DOI: 10.4236/ijg.2015.612102
Abstract: In this paper, it is both intended to effectively transfer and emphasize the relationship between geospatial data and software applications while presenting the learning activities which required software competences and presented some software techniques related with geomatic engineering. Effective software competence in geomatic is required for both the combination of information-communication technologies and interdisciplinary collaborative learning activities. The essential way to keep up with future competences is adaptation to different types of information technologies. Today, it is obviously seen that the using of interest-activated technology is a sine qua non condition of engineering education. The main focusing point of this paper is to present some learning suggestions while developing a software related course content in Geomatic to empower engineering education.
Rhinocerebral mucormycosis treated with 32 gram liposomal amphotericin B and incomplete surgery: a case report
Atahan A ?agatay, Serkan S ?ncü, Semra S ?alangu, Taner T Yildirmak, Halit H ?zsüt, Haluk H Eraksoy
BMC Infectious Diseases , 2001, DOI: 10.1186/1471-2334-1-22
Abstract: A 31-year-old diabetic man presented to the outpatient clinic with the following signs and symptoms: headache, periorbital pain, swelling and loss of vision in the right eye. On physical examination his right eye was red and swollen. There was periorbital cellulitis and the conjunctiva was edematous. KOH preparation of purulent discharge showed broad, ribbonlike, aseptate hyphae when examined under a fluorescence microscope. Cranial MRI showed involvement of the right orbit, thrombosis in cavernous sinus and infiltrates at ethmoid and maxillary sinuses. Mucormycosis was diagnosed based on these findings. Amphotericin B (AmBisome?; 2 mg/kg.d) was initiated after the test doses. Right orbitectomy and right partial maxillectomy were performed; the lesions in ethmoid and maxillary sinuses were removed. The duration of the liposomal amphotericin B therapy was approximately 6 months and the total dose of liposomal amphotericin B used was 32 grams. Liposomal amphotericin B therapy was stopped six months later and oral fluconazole was started.Although a total surgical debridement of the lesions could not be performed, it is remarkable that regression of the disease could be achieved with medical therapy alone.Mucormycosis (or zygomycosis) is the term for infection caused by fungi of the order Mucorales [1-4]. Mucoraceae may produce severe disease in susceptible individuals, notably patients with diabetes and leukemia. Rhinocerebral mucormycosis most commonly manifests itself in the setting of poorly controlled diabetes, especially with ketoacidosis. The causative organism in most cases is Rhizopus oryzae. Progression of the disease is usually rapid, although it may become indolent if ketoacidosis resolves. Because of the rapidity with which this disease progresses, prompt and aggressive therapy is essential [5-7]. Since the introduction of combined therapy with amphotericin B and surgery, more than 80% of the patients can be expected to survive [6-8]. Administration of amph
Some Proximate Analysis of African Pear (Dacryodes Edulis)
NC Onuegbu, NC Ihediohanma
Journal of Applied Sciences and Environmental Management , 2008,
Abstract: Some physical and chemical properties of African pear (Dacryodes edulis) samples from nine different trees were analysed in order to determine the level of differences that exist between trees. The length of the individual fruits ranged from 39.86 mm to 80.76 mm while the weight ranged from 15.97 g to 39.36 g. Significant differences (p . 0.05) were observed between the samples for all the parameters measured. Fruit density showed a negative correlation (r = -0.86) with the pulp/seed ratio. Significant differences were also observed in the proximate composition of the African pear pulp. The major components of the pulp were moisture (36.5% to 53.82%), oil (18.81% to 38.36%) and protein (11.09% to 19.19%). The pulp acidity ranged from 0.92% to 1.69% expressed as citric acid.
A Preliminary Investigation into Critical Thinking Skills of Urban High School Students: Role of an IT/STEM Program  [PDF]
Mesut Duran, Serkan Sendag
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.32038
Abstract: This paper reports the development of critical thinking of urban high school students in an IT/STEM program-using information technology (IT) within the context of science, technology, engineering, and mathematics (STEM). The study used a quasi-experimental time-series design, involving 47 initial participants in an eighteen-month intervention period. Data were collected from the Test of Everyday Reasoning (TER), which provides an overall score on critical thinking skill (CTS) and five sub-scale scores (analysis, inference, evaluation, inductive reasoning, and deductive reasoning). Findings indicate that based on a mean score of 15.77, the average participant scored between the 16th and 19th percentiles at the beginning of the program compared to an aggregated national sample. Participants who completed the program and responded to all three time-series TER tests (14) significantly improved their critical thinking skills throughout the program. Program completers’ overall post-program CTS test score was more homogeneous than the pre-program scores with a 20.07 mean score. In addition, data showed significant improvement in inductive reasoning skills of the program participants during the first nine months with continuing improvement in the second nine months. In contrast, data presented improved inference skills during the first nine months with significant gains during the second half of the program. The study estimates the relative effects of IT/STEM experiences with technology-enhanced, inquiry and design-based collaborative learning strategies on CTS of urban high school students.
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