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Search Results: 1 - 10 of 21535 matches for " Seo Woo Han "
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Perspective Projection Algorithm Enabling Mobile Device’s Indoor Positioning  [PDF]
Seo Woo Han, Yun Jung Lee, Ji Hyeok Yun, Chang Yong Han, Dae Ho Lee, Doug Young Suh
Journal of Computer and Communications (JCC) , 2018, DOI: 10.4236/jcc.2018.61017
In order to improve the user’s satisfaction with the augmented reality (AR) technology and the accuracy of the service, it is important to obtain the exact position of the user. Frequently used techniques for finding outdoors locations is the global positioning system (GPS), which is less accurate indoors. Therefore, an indoor position is measured by comparing the reception level about access point (AP) signal of wireless fidelity (Wi-Fi) or using bluetooth low energy (BLE) tags. However, Wi-Fi and Bluetooth require additional hardware installation. In this paper, the proposed method of estimating the user’s position uses an indoor image and indoor coordinate map without additional hardware installation. The indoor image has several feature points extracted from fixed objects. By matching the feature points with the feature points of the user image, we can obtain the position of the user on the Indoor map by obtaining six or more pixel coordinates from the user image and solving the solution using the perspective projection formula. The experimental results show that the user position can be obtained more accurately in the indoor environment by using only the software without additional hardware installation.
Both Basic and Acidic Amino Acid Residues of Are Involved in Triggering Substate of RyR1
In Ra Seo,Dae Eun Kang,Dong Woo Song,Do Han Kim
Journal of Biomedicine and Biotechnology , 2011, DOI: 10.1155/2011/386384
Abstract: Imperatoxin A (IpTxa) is known to modify the gating of skeletal ryanodine receptor (RyR1). In this paper, the ability of charged aa residues of IpTxa to induce substate of native RyR1 in HSR was examined. Our results show that the basic residues (e.g., Lys19, Lys20, Lys22, Arg23, and Arg24) are important for producing substate of RyR1. In addition, other basic residues (e.g., Lys30, Arg31, and Arg33) near the C-terminus and some acidic residues (e.g., Glu29, Asp13, and Asp2) are also involved in the generation of substate. Residues such as Lys8 and Thr26 may be involved in the self-regulation of substate of RyR1, since alanine substitution of the aa residues led to a drastic conversion to the substate. The modifications of the channel gating by the wild-type and mutant toxins were similar in purified RyR1. Taken together, the specific charge distributions on the surface of IpTxa are essential for regulation of the channel gating of RyR1.
Canine mesenchymal stem cells are effectively labeled with silica nanoparticles and unambiguously visualized in highly autofluorescent tissues
Sei-Myoung Han, Hee-Woo Lee, Dong-Ha Bhang, Kyoung-Won Seo, Hwa-Young Youn
BMC Veterinary Research , 2012, DOI: 10.1186/1746-6148-8-145
Abstract: We examined the effect of silica nanoparticle labeling on stem cell morphology, viability and differentiation as compared with those of unlabeled control cells. After 4?h of incubation with silica nanoparticles, they were internalized by canine MSCs without a change in the morphology of cells compared with that of control cells. The viability and proliferation of MSCs labeled with silica nanoparticles were evaluated by a WST-1 assay and trypan blue exclusion. No effects on cell viability were observed, and the proliferation of canine MSCs was not inhibited during culture with silica nanoparticles. Furthermore, adipogenic and osteogenic differentiation of silica nanoparticle-labeled canine MSCs was at a similar level compared with that of unlabeled cells, indicating that silica nanoparticle labeling did not alter the differentiation capacity of canine MSCs. Silica nanoparticle-labeled canine MSCs were injected into the kidneys of BALB/c mice after celiotomy, and then the mice were sacrificed after 2 or 3?weeks. The localization of injected MSCs was closely examined in highly autofluorescent renal tissues. Histologically, canine MSCs were uniformly and completely labeled with silica nanoparticles, and were unambiguously imaged in histological sections.The results of the current study showed that silica nanoparticles are useful as an effective labeling marker for MSCs, which can elucidate the distribution and fate of transplanted MSCs.Adult mesenchymal stem cells (MSCs) are a cellular tool with promising application in both veterinary and human medicine. MSCs have the potential to repair tissues [1-4] and improve the function of damaged organs. Thus, many clinical trials are in progress to evaluate the therapeutic potentials of MSCs for treating renal failure, diabetes mellitus and heart failure [5-9].Tracking of stem cells is essential for evaluating cell replacement and therapeutic strategies [10]. In addition, long-term labeling of stem cells is critical to elucidat
Inhibitory Effects of Anthocyanins on Secretion of Helicobacter pylori CagA and VacA Toxins
Sa-Hyun Kim, Min Park, Hyunjun Woo, Nagendran Tharmalingam, Gyusang Lee, Ki-Jong Rhee, Yong Bin Eom, Sang Ik Han, Woo Duck Seo, Jong Bae Kim
International Journal of Medical Sciences , 2012,
Abstract: Anthocyanins have been studied as potential antimicrobial agents against Helicobacter pylori. We investigated whether the biosynthesis and secretion of cytotoxin-associated protein A (CagA) and vacuolating cytotoxin A (VacA) could be suppressed by anthocyanin treatment in vitro. H. pylori reference strain 60190 (CagA+/VacA+) was used in this study to investigate the inhibitory effects of anthocyanins; cyanidin 3-O-glucoside (C3G), peonidin 3-O-glucoside (Peo3G), pelargonidin 3-O-glucoside (Pel3G), and malvidin 3-O-glucoside (M3G) on expression and secretion of H. pylori toxins. Anthocyanins were added to bacterial cultures and Western blotting was used to determine secretion of CagA and VacA. Among them, we found that C3G inhibited secretion of CagA and VacA resulting in intracellular accumulation of CagA and VacA. C3G had no effect on cagA and vacA expression but suppressed secA transcription. As SecA is involved in translocation of bacterial proteins, the down-regulation of secA expression by C3G offers a mechanistic explanation for the inhibition of toxin secretion. To our knowledge, this is the first report suggesting that C3G inhibits secretion of the H. pylori toxins CagA and VacA via suppression of secA transcription.
The Community Structure of Macrozoobenthos and Its Temporal Change on the Gapo Artificial Tidal Flat in Masan Bay, Korea  [PDF]
Jin-Woo Choi, Jin-Young Seo, Soonmo An
Open Journal of Marine Science (OJMS) , 2013, DOI: 10.4236/ojms.2013.34022

This study was conducted to get some basic information on the community structure of macrozoobenthos and its temporal change at 3 sites on the Gapo artificial tidal flat within Masan Bay from March 2002 to April 2004 when 8 years passed after the construction. The Gapo artificial tidal flat was constructed by filling the dredged contaminated sediments of MasanBayfrom 1990 to 1993. The surface sediment consisted of fine particles, but the grain size at the tidal flat has changed from mud to muddy sand by adding coarse particles for manila clam aquaculture by local fishermen from 2002. A total of 35 faunal species including 23 species at the upper tidal flat, 28 species at the lower tidal flat and 30 species in the tidal channel were collected during the study period. Polychaete worms were the most dominant fauna in species number and total faunal density, but mollusks were the most dominant in biomass. There was a specific species composition along tidal level. At the upper tidal flat, Prionospio japonicus, Sigambra tentaculata, and Neanthes succinea were dominant and at the lower tidal flat, N. succinea, P. japonicus, Corophium sinensis, and Ruditapes philipinarum were dominant while

Parental Involvement in Child’s Development: Father vs. Mother  [PDF]
Yeoh Si Han, Woo Pei Jun
Open Journal of Medical Psychology (OJMP) , 2013, DOI: 10.4236/ojmp.2013.24B001

This study aims to investigate on Malaysian young adults’ perceived father and mother involvement. A questionnaire survey with Father Involvement Scale, and Mother Involvement Scale was carried out on 100 male and 100 female local university and college student aged 18 and 25 years old. The findings show that mothers engaged more in expressive and mentoring/advising involvement as compared to fathers. However, there is no difference between fathers and mothers in instrumental involvement. This study gives us a better understanding on the pattern of parental involvement in Malaysia and hence helps to promote better parent-child relationship.

Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome: A Double-Blind, Randomized, Placebo-Controlled Trial
Seok-Jae Ko,Gajin Han,Seul-Ki Kim,Jae-Gu Seo,Won-Seok Chung,Bongha Ryu,Jinsung Kim,Inkwon Yeo,Beom-Joon Lee,Jin-Moo Lee,Jae-Woo Park
Evidence-Based Complementary and Alternative Medicine , 2013, DOI: 10.1155/2013/824605
Abstract: Introduction. Although combination therapy with herbal medicine and probiotics is gaining popularity for controlling diarrhea-dominant irritable bowel syndrome (D-IBS) symptoms, few studies have investigated its clinical effects. Materials and Methods. Fifty-three patients with D-IBS were randomly allocated into 1 of the following 4 groups: herbal medicine (Gwakhyangjeonggisan; GJS) plus probiotics (Duolac7S; DUO), GJS plus placebo DUO, placebo GJS plus DUO, and placebo GJS plus placebo DUO. The study period consisted of a 2-week run-in, 8 weeks of administration, and 2 weeks of follow-up. The primary outcomes were weekly adequate relief (AR) of overall IBS symptoms and the proportion of responders (PR) during the administration period. The secondary outcomes included individual IBS symptoms, stool assessment, and quality of life. Changes of intestinal microbiota and intestinal permeability were also analyzed. Results and Discussion. Weekly AR was not different among the 4 groups throughout the treatment period. However, the 3 treatment groups exhibited significant improvements in PR compared to the findings in the placebo group. In the intestinal microbiota assessment, herbal medicine and probiotics synergistically increased beneficial bacteria counts. Conclusion. Combination therapy with herbal medicine and probiotics appears to relieve overall IBS symptoms by synergistically increasing beneficial intestinal microbe counts. 1. Introduction Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain, discomfort, and bowel disturbances without any structural abnormality [1]. IBS may cause significant inconvenience to patients, impair their social functioning, and deteriorate their quality of life [2]. The involvement of various factors in the pathophysiology of IBS makes treatment more difficult [3]. Factors such as imbalances of intestinal microbiota and increased intestinal permeability have been identified as important elements in the pathophysiology of IBS [4, 5]. Therefore, therapeutic approaches aimed at resolving disturbances in the intestinal microbiota and maintaining mucosal barrier homeostasis can be helpful in the treatment of IBS. However, due to dissatisfying results with conventional IBS treatments, complementary therapies including herbal medicine and probiotics are becoming attractive options for many patients [6]. Herbal medicines have long been used in Asian countries due to their safety and having only a few side effects. Gwakhyangjeonggisan (GJS; Kkako-shoki-san in Kampo Medicine;
Therapeutic Effects of Acupuncture through Enhancement of Functional Angiogenesis and Granulogenesis in Rat Wound Healing
Sang In Park,Yun-Young Sunwoo,Yu Jin Jung,Woo Chul Chang,Moon-Seo Park,Young-An Chung,Lee-So Maeng,Young-Min Han,Hak Soo Shin,Jisoo Lee,Sang-Hoon Lee
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/464586
Abstract: Acupuncture regulates inflammation process and growth factors by increasing blood circulation in affected areas. In this study, we examined whether acupuncture has an effect on wound healing in injured rat. Rats were assigned randomly into two groups: control group and acupuncture group. Acupuncture treatment was carried out at 8 sites around the wounded area. We analyzed the wound area, inflammatory cytokines, proliferation of resident cells, and angiogenesis and induction of extracelluar matrix remodeling. At 7 days after-wounding the wound size in acupuncture-treat group was decreased more significantly compared to control group. In addition, the protein levels of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) were significantly decreased compared to the control at 2 and 7 days post-wounding. Also, we analyzed newly generated cells by performing immunostaining for PCNA and using several phenotype markers such as CD-31, α-SMA, and collagen type I. In acupuncture-treated group, PCNA-positive cell was increased and PCNA labeled CD-31-positive vessels, α-SMA- and collagen type I-positive fibroblastic cells, were increased compared to the control group at 7 days post-wounding. These results suggest that acupuncture may improve wound healing through decreasing pro-inflammatory response, increasing cell proliferation and angiogenesis, and inducing extracellular matrix remodeling. 1. Introduction In normal wound repair, well-controlled and coordinated balance between immune defense and epithelial cell proliferation and differentiation is essential. Wound healing involves a complex process that includes inflammation, proliferation, epithelialization, angiogenesis, and collagen matrix formation [1, 2]. During the inflammatory phase of skin repair, neutrophils and macrophages infiltrate the wounded area to clear damaged tissue and produce cytokines such as macrophage inflammatory protein (MIP)-1α, interleukin (IL) family, and tumor necrosis factor-α (TNF-α) to expedite the repair process [3]. Epithelialization occurs by migration and proliferation of keratinocytes from the wound edges and by differentiation of stem cells from the remaining hair follicle bulbs [4, 5]. Also, collagen deposition occurs by the influx of growth factors such as transforming growth factor-β, fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF) that are secreted by macrophages, platelets, and fibroblasts. Moreover, angiogenesis is a multistep process that involves endothelial cell sprouting from the parent vessel,
The Nuclear Inclusion a (NIa) Protease of Turnip Mosaic Virus (TuMV) Cleaves Amyloid-β
Hye-Eun Han,Saravanan Sellamuthu,Bae Hyun Shin,Yong Jae Lee,Sungmin Song,Ji-Seon Seo,In-Sun Baek,Jeomil Bae,Hannah Kim,Yung Joon Yoo,Yong-Keun Jung,Woo Keun Song,Pyung-Lim Han,Woo Jin Park
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0015645
Abstract: The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) is responsible for the processing of the viral polyprotein into functional proteins. NIa was previously shown to possess a relatively strict substrate specificity with a preference for Val-Xaa-His-Gln↓, with the scissile bond located after Gln. The presence of the same consensus sequence, Val12-His-His-Gln15, near the presumptive α-secretase cleavage site of the amyloid-β (Aβ) peptide led us to hypothesize that NIa could possess activity against Aβ.
Combinatorial proofs of inverse relations and log-concavity for Bessel numbers
Hyuk Han,Seunghyun Seo
Mathematics , 2004,
Abstract: Let the Bessel number of the second kind B(n,k) be the number of set partitions of [n] into k blocks of size one or two, and let the Bessel number of the first kind b(n,k) be a certain coefficient in n-th Bessel polynomial. In this paper, we show that Bessel numbers satisfy two properties of Stirling numbers: The two kinds of Bessel numbers are related by inverse formulas, and both Bessel numbers of the first kind and the second kind form log-concave sequences. By constructing sign-reversing involutions, we prove the inverse formulas. We review Krattenthaler's injection for the log-concavity of Bessel numbers of the second kind, and give a new explicit injection for the log-concavity of signless Bessel numbers of the first kind.
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