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DEVELOPMENT OF FINE MOTOR COORDINATION AND VISUAL-MOTOR INTEGRATION IN PRESCHOOL CHILDREN
Haris MEMISEVIC,Selmir HADZIC
Journal of Special Education and Rehabilitation , 2013, DOI: 10.2478/v10215-011-0032-4
Abstract: Fine motor skills are prerequisite for many everyday activities and they are a good predictor of a child's later academic outcome. The goal of the present study was to assess the effects of age on the development of fine motor coordination and visual-motor integration in preschool children. The sample for this study consisted of 276 preschool children from Canton Sara-jevo, Bosnia and Herzegovina. We assessed children's motor skills with Beery Visual Motor Integration Test and Lafayette Pegboard Test. Data were analyzed with one-way ANOVA, followed by planned com-parisons between the age groups. We also performed a regression analysis to assess the influence of age and motor coordination on visual-motor integration. The results showed that age has a great effect on the development of fine motor skills. Furthermore, the results indicated that there are possible sensitive periods at preschool age in which the development of fine motor skills is accelerated. Early intervention specialists should make a thorough evaluations of fine motor skills in preschool children and make motor (re)habilitation programs for children at risk of fine motor delays.
Modulation of dendritic cell functions by viral IL-10 encoded by human cytomegalovirus
Selmir Avdic,Barry Slobedman
Frontiers in Microbiology , 2014, DOI: 10.3389/fmicb.2014.00337
Abstract: Human cytomegalovirus (HCMV), a clinically important β-herpesvirus, is a master of evasion and modulation of the host immune system, including inhibition of a number of dendritic cell (DC) functions. DCs play a central role in co-ordination of the immune response against pathogens and any disturbance of DC functions can result in a cascade effect on a range of immune cells. Recently, the HCMV gene UL111A, which encodes viral homologs of human interleukin 10, has been identified as a strong suppressor of a number of DC functions. In this mini review, we focus on HCMV encoded viral IL-10 mediated inhibitory effects on DCs and implications for the development of an effective HCMV vaccine.
REVIEW: Medical management of ‘failing’ Kasai portoenterostomy
N Hadzic
South African Medical Journal , 2012,
Abstract: The only effective treatment for ‘failing’ Kasai portoenterostomy is liver transplantation (LT). However, to maximise a patient’s chances to achieve the proclaimed >95% survival with sequential surgical management, medical follow-up and treatment must be planned carefully. This includes routine fat-soluble vitamin supplementation with choleretics, aggressive nutritional support, regular ultrasonography, optimal general paediatric care, and psychological support for the family once complications arise. Careful timing of LT is of critical importance, although recent trends include earlier consideration of LT in children with biliary atresia. This management can only be offered through centralised, specialised national services. Due to its ramifications in paediatric surgery, dietetics, metabolic, social, adolescent and transplantation medicine, paediatric hepatology is a fine example of patient care that is genuinely multidisciplinary.
On coincidence theorems for a family of mappings in convex metric spaces
Olga Hadzic
International Journal of Mathematics and Mathematical Sciences , 1987, DOI: 10.1155/s016117128700053x
Abstract: In this paper, a theorem on common fixed points for a family of mappings defined on convex metric spaces is presented. This theorem is a generalization of the well known fixed point theorem proved by Assad and Kirk. As an application a common fixed point theorem in metric spaces with a convex structure is obtained.
A constraint variational problem arising in stellar dynamics
Mahir Hadzic
Mathematics , 2006,
Abstract: We use the compactness result of A. Burchard and Y. Guo (cf. \cite{BuGu}) to analyze the reduced 'energy' functional arising naturally in the stability analysis of steady states of the Vlasov-Poisson system (cf. \cite{SaSo} and \cite{Ha}). We consider the associated variational problem and present a new proof that puts it in the general framework for tackling the variational problems of this type, given by Y. Guo and G. Rein (cf. \cite{Re1} and \cite{Re2}).
Orthogonality conditions and asymptotic stability in the Stefan problem with surface tension
Mahir Hadzic
Mathematics , 2011, DOI: 10.1007/s00205-011-0463-6
Abstract: We prove nonlinear asymptotic stability of steady spheres in the two-phase Stefan problem with surface tension. Our method relies on the introduction of appropriate orthogonality conditions in conjunction with a high-order energy method.
Human Cytomegalovirus Encoded Homologs of Cytokines, Chemokines and their Receptors: Roles in Immunomodulation
Brian P. McSharry,Selmir Avdic,Barry Slobedman
Viruses , 2012, DOI: 10.3390/v4112448
Abstract: Human cytomegalovirus (HCMV), the largest human herpesvirus, infects a majority of the world’s population. Like all herpesviruses, following primary productive infection, HCMV establishes a life-long latent infection, from which it can reactivate years later to produce new, infectious virus. Despite the presence of a massive and sustained anti-HCMV immune response, productively infected individuals can shed virus for extended periods of time, and once latent infection is established, it is never cleared from the host. It has been proposed that HCMV must therefore encode functions which help to evade immune mediated clearance during productive virus replication and latency. Molecular mimicry is a strategy used by many viruses to subvert and regulate anti-viral immunity and HCMV has hijacked/developed a range of functions that imitate host encoded immunomodulatory proteins. This review will focus on the HCMV encoded homologs of cellular cytokines/chemokines and their receptors, with an emphasis on how these virus encoded homologs may facilitate viral evasion of immune clearance.
Assessment of Micro Loan Payment using Structured Data Mining Techniques: The Case of Indonesian People' Credit Bank
Novita Ikasari,Fedja Hadzic
Lecture Notes in Engineering and Computer Science , 2012,
Abstract:
Stability for the spherically symmetric Einstein-Vlasov system - a coercivity estimate
Mahir Hadzic,Gerhard Rein
Physics , 2012, DOI: 10.1017/S030500411300056X
Abstract: The stability of static solutions of the spherically symmetric, asymptotically flat Einstein-Vlasov system is studied using a Hamiltonian approach based on energy-Casimir functionals. The main result is a coercivity estimate for the quadratic part of the expansion of the natural energy-Casimir functional about an isotropic steady state. The estimate shows in a quantified way that this quadratic part is positive definite on a class of linearly dynamically accessible perturbations, provided the particle distribution of the steady state is a strictly decreasing function of the particle energy and provided the steady state is not too relativistic. This should be an essential step in a fully non-linear stability analysis for the Einstein-Vlasov system. In the present paper it is exploited for obtaining a linearized stability result.
Stability in the Stefan problem with surface tension (I)
Mahir Hadzic,Yan Guo
Mathematics , 2008,
Abstract: We develop a high-order energy method to prove asymptotic stability of flat steady surfaces for the Stefan problem with surface tension - also known as the Stefan problem with Gibbs-Thomson correction.
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