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Search Results: 1 - 10 of 3420 matches for " Selcuk Mustafa Secen "
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Determination of Fatty Acid Composition and Phenolic Content of Seed Oils of Cappadocia Region Grape Varieties
Selcuk Mustafa Secen
Aksaray University Journal of Science and Engineering , 2017, DOI: -
Abstract: The grape (Vitis vinifera) from the Vitaceae family is the most grown fruit species in the world. Turkey has an important place in the world winegrowing due to favorable climatic conditions. The Cappadocia region is among the most important regions in Turkish wine production. The most grown varieties in this region are Emir and Dimrit grapes. Grape seeds are a by-product of the wine-making industry and fruit juice. Most of the total amount of grapes is used in wine making. In a few weeks of the harvest season, around 10 million tons of grape pods are emerging in the world. Grape seed oil contains omega 6, which is essential for omega fatty acids, at a high rate and also they are rich in polyphenolic compounds with strong biological effects. Due to the fatty acids and phenolic content of these products, it is aimed to be a new food source for human nutrition and at the same time to contribute to the reduction of factory product costs. The highest fatty acids identified in all varieties were linoleic acid (C18: 2), followed by oleic acid (C18: 1), palmitic acid (C16: 0) and stearic acid (C18: 0). Total phenolic substance content ranges between 70 and 84 (g GAE/kg ekstract) among the varieties. The phenolic content of the Dimrit grape seed is higher than Emir Grape seeds. According to these results, the oils of Cappadocia grape varieties Emir and Dimrit can be proposed as a new food source for human nutrition at the same time to contribute to the reduction of factory product costs.
Comparison of Fractional Flow Reserve-Guided Revascularization Strategies in Isolated Proximal Left Anterior Descending Coronary Artery Disease  [PDF]
Mehmet Timur Selcuk, Enis Grbovic, Orhan Maden, Hatice Selcuk, Murat Gül, Kevser Gülcihan Balci, Mustafa Mücahit Balci
Open Journal of Internal Medicine (OJIM) , 2018, DOI: 10.4236/ojim.2018.83017
Abstract: The data about FFR-guided revascularization in isolated proximal LAD disease are limited and studies comparing long-term outcomes of FFR-guided PCI versus FFR-guided CABG in single-vessel proximal LAD disease are lacking. We aimed to assess the 4-year long-term safety and effectiveness of fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) and FFR-guided coronary artery bypass graft surgery (CABG) for the treatment of proximal left anterior descending (LAD) lesions. The study included 129 patients with functionally significant (FFR ≤ 0.80) isolated proximal LAD stenosis (PCI, 88 patients vs. CABG, 41). Clinical endpoints were assessed by Kaplan-Meier method and compared by the log-rank test. At a mean follow-up time of 47 ± 12 months, a higher incidence of myocardial infarction in the PCI group (PCI: 32% vs. CABG: 15%; p = 0.003) and a higher incidence of stroke in the CABG group (CABG: 3 (7%) vs. PCI 0 (0%); p = 0.031) were observed. However, there were no significant differences in the primary composite endpoint, death and target vessel revascularization between PCI and CABG groups. The PCI and CABG in isolated proximal LAD lesions yielded similar long-term outcomes regarding the primary composite clinical endpoints. However, stroke was more frequent in the CABG group than in the PCI group.
Revisiting the Predictive Factors for Intra-Operative Complications of Rigid Ureteroscopy: A 15-Year Experience
Orhan Tanriverdi,Mesrur Selcuk Silay,Mustafa Kadihasanoglu,Mustafa Aydin
Urology Journal , 2012,
Abstract: PURPOSE: To revise the predictive factors for intra-operative complications of rigid ureteroscopy in the treatment of ureteral calculi. MATERIALS AND METHODS: During a 15-year period (1993 to 2008), a total of 1496 consecutive patients who had undergone 1660 ureteroscopy procedures were retrospectively reviewed. After exclusion of the cases for diagnostic purposes, diseases other than ureteral calculi, and repeated ureteroscopy procedures, 1189 patients were left as the study population. Those patients were then divided into two groups based on the presence of the complications: complication–positive (group 1, n = 57) and complication–negative (group 2, n = 1132). Both groups were statistically compared regarding patients’ age and gender, stone surface area, lateralization and localization of the stone, impaction of the stone, type of the ureteroscope, necessity of ureteral orifice dilation, and use of a catheter during and after the procedure. Furthermore, the effect of leaving the fragmented stones in situ small enough to pass spontaneously (break’n’leave) on occurring of the complications has been investigated. RESULTS: The complication rate was recorded as 4.7%. Success rate after a single intervention was 86.3%, whereas increased to 94.1% after ancillary procedures. Stone surface area, lateralization, and type of lithotripter used were comparable between the groups, but impacted stones and the stones located at the upper ureters were associated with significantly increased complication rates. Furthermore, significantly less complication has been observed in cases where we performed break’n’leave. Furthermore, multivariate analysis revealed that stone impaction and failure to adhere to the “break’n’leave” principle were the independent predictors of occurring of the complications. CONCLUSION: Ureteroscopy is safe and effective in the treatment of ureteral calculi. Careful attention for the patients having a potential for occurrence of the complications and selection of the techniques are of importance for reducing untoward events.
Homotopy Analysis Method for Equations of the Type Δ2=b(x,y) and Δ2u=b(x,y,u)  [PDF]
Selcuk Yildirim
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.34049
Abstract:

In this paper, the homoto pyanalysis method (HAM) is presented to solve some of engineering problems. The homotopy analysis method is applied in obtaining exact solutions for equations of the type?Δ2=b(x,y) and ?Δ2u=b(x,y,u)on an elliptical domain. Exact solutions are presented for several examples involving to demon strate the applic ability and efficiency of HAM.

The Effect of a Lactic Acid Bacteria Inoculant on Corn Silage Ensiled at the Different Stages of Vegetation
O. Hakan Muglali,Mustafa Salman,Zehra Selcuk,Bugra Genc,Filiz Karadas
Veterinary Research , 2012, DOI: 10.3923/vr.2012.41.45
Abstract: The study was carried out to investigate the effect of a lactic acid bacteria inoculant applied to fresh corn crop harvested at early milk, milk and dough stages on silage quality and some chemical composition of corn silage. Corn crop was harvested at early milk stage (19.3% dry matter content), milk stage (1/2 milk line in corn grain, 27.2% dry matter content) and dough stage (36.9% dry matter content). A total of six experimental groups including one control and one treatment group containing a Lactic Acid Bacteria inoculant (LAB) were used for each stage. The silage material was tightly filled in 192 glass jars. Eight jars of each group were opened on days 15, 30, 45 and 60th of ensiling and crude protein, metabolisable energy, the pH value, ammonia nitrogen, lactic acid, acetic acid, propionic acid and butyric acid concentrations were determined. Although, there was a difference (p<0.05) in pH value of corn silage ensiled at early milk stage between control and treatment groups on the 45 and 60th days of ensiling, the pH values of them were <4.0. On the 45 and 60th days of ensiling, there was no difference in ammonia nitrogen and organic acid levels of control and treatment groups of corn silage ensiled at early milk stage, milk stage and dough stage. In conclusion, a lactic acid bacteria inoculant had no beneficial effects compared to controls on corn silages ensiled at early milk stage, milk stage and dough stage.
Antimicrobial Susceptibilities of Brucella Isolates from Various Clinical Speciemens
Yasemin Bayram, Hanifi Korkoca, Cenk Aypak, Mehmet Parlak, Aytekin Cikman, Selcuk Kilic, Mustafa Berktas
International Journal of Medical Sciences , 2011,
Abstract: Purpose: Brucellosis is a worldwide zoonotic disease and still constitutes a major public health problem. In the study we claimed to identify Brucella species from clinical samples of patients with active brucellosis from Van region of Eastern Anatolia and to determine in vitro antimicrobial susceptibilities of these strains to commonly used anti-Brucella agents and a possible new alternative tigecycline. Materials and Methods: A total of 56 Brucella isolates were enrolled the study and the identification of the isolates were based on conventional methods. In vitro activities of antimicrobials were evaluated by the E test method. Results: All isolates were identified as B. melitensis. MIC90 values of doxycycline, streptomycin, rifampin, trimethoprim-sulfamethoxazole and tigecycline were 0.064 mg/L, 1 mg/L, 2 mg/L, 0.125 mg/L and 0.094 mg/L, respectively. Tigecycline had low MIC50 and MIC90 values against all B. melitensis strains; the highest MIC observed was 0.25 μg/mL. Conclusion: Our data suggest that tigecycline can be a therapeutic alternative option for the treatment of brucellosis.
Chromium picolinate and chromium histidinate protects against renal dysfunction by modulation of NF-κB pathway in high-fat diet fed and Streptozotocin-induced diabetic rats
Mustafa Selcuk, Bilge Aygen, Ayhan Dogukan, Zeynep Tuzcu, Fatih Akdemir, James R Komorowski, Mustafa Atalay, Kazim Sahin
Nutrition & Metabolism , 2012, DOI: 10.1186/1743-7075-9-30
Abstract: Male Wistar rats were divided into six groups. Group I received a standard diet (8% fat) and served as a control; Group II was fed with a standard diet and received CrPic; Group III was fed with a standard diet and received CrHis; Group IV received a high fat diet (HFD, 40% fat) for 2 weeks and then were injected with streptozotocin (STZ) (HFD/STZ); Group V was treated as group IV (HFD/STZ) but supplemented with CrPic for 12 weeks. Group VI was treated as group IV (HFD/STZ) but supplemented with CrHis.The increased NF-κβ p65 in the HFD/STZ group was inhibited by CrPic and CrHis supplementation (P < 0.05). In STZ-treated rats, a significant decrease in levels of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IκBα) was found in kidney tissues when compared to control rats (P < 0.05). A significant increase in the levels of IκBα was observed in CrPic- and CrHis-treated rats when compared with STZ-treated rats. Renal Nrf2 levels were significantly decreased in diabetic rats compared with the control rats. There was a higher tendency for increase of kidney Nrf2 level and decrease in kidney NFκBp65 levels and 4- hydroxyl nonenal (4-HNE) protein adducts (P < 0.05) in diabetic rats.Our result show that in kidney tissue CrHis/CrPic increases Nrf2 level, parallelly decreases NF-κB and partially restores IκBα levels in HFD/STZ group, suggesting that CrPic and CrHis may play a role in antioxidant defense system via the Nrf2 pathway by reducing inflammation through NF-κβ p65 inhibition. Moreover, a greater reduction in NF-κB expression and greater increases in expressions of IκBα and Nrf2 in diabetic rats supplemented with CrHis than rats supplemented with CrPic suggest that CrHis has more favorable effects than CrPic.Nutrition plays an important role in the development and also in the prevention of cancer, cardiovascular diseases, and diabetes. A high-fat diet can induce obesity and metabolic disorders, insulin resistance, dyslipidemia, and
Underlying Factors of Occupational Accidents: The Case of Turkey  [PDF]
Fatih Yilmaz, Selcuk Alp
Open Journal of Safety Science and Technology (OJSST) , 2016, DOI: 10.4236/ojsst.2016.61001
Abstract: An average of 80 thousand occupational accidents occurs each year in Turkey and 1500 workers are lost their lives. In accordance to “policy of preventive approach”, many legal arrangements have been made in Turkey. In this context, weight to issues such as risk assessment and preventive OHS services is given; however, employee training, employee participation, labour inspect, and periodic checks in working areas such as maintenance and audit have not been achieved. The level of implementation of legal arrangements was inadequate. Research was carried out to determine the significance rate of the factors that cause accidents in 5 sectors with the highest number of occupational accidents in Turkey. Questionnaires administered to experienced safety specialists were reviewed by analyzing with the fuzzy TOPSIS method. According to the results, especially in the construction and coal mining sectors and all sectors in general, employee training, employee participation and periodic maintenance in the workplace are more important accident prevention factors than risk assessment and preventive OH & S services. It is seen that for the prevention of accidents, all measures should be implemented by systematic and by a multidisciplinary approach.
A Grain Flow Model to Simulate Grain Yield Sensor Response
Selcuk Arslan
Sensors , 2008, DOI: 10.3390/s8020952
Abstract: The objective of this study was to develop a flow model for grain combinesbased on the laboratory and field response of an impact based grain flow sensor. The grainflow model developed in this study is of first order with constant coefficients. A computercode was written to solve the model and to simulate the response of a yield sensor whoseresponse had been determined previously for various types of flow rate inputs both in fieldand laboratory experiments. The computer program for the simulation can alsocompensate for the time delay. The simulation results of the theoretical model suited wellto the experimental data and showed that the model effectively shows the input-outputrelationship of grain flow through a grain combine. This model could be used for periodicflow signals acquired from grain yield sensors. It was concluded that the model postulatedin this study could be further developed to determine the grain yield entering the combineusing the outlet flow rate measured by a yield sensor.
Nurses' perceptions of online continuing education
Selcuk Karaman
BMC Medical Education , 2011, DOI: 10.1186/1472-6920-11-86
Abstract: The survey method was used in this quantitative study to reveal perception levels and relationship with related variables. Data were collected through an online instrument from a convenience sample of 1041 Registered Nurses (RNs) at an online bachelor's degree program. Descriptive and inferential analysis techniques were performed.Nurses generally have positive perceptions about online learning (X = 3.86; SD = 0.48). A significant difference was seen between nurses who used computers least and those with the highest computer usage [F (3, 1033) = 3.040; P < .05]. Neither nurses' ages nor lengths of working experience are significantly related to perceptions of online programs (r = -.013; P > .05 and r = -.036; P > .05, respectively). Nurses' perceptions are significantly different depending on the settings where they work [F (3,989) = 3.193; P < .05]. The difference between perceptions of nurses living in urban areas (X = 3.82; SD = .51) and those living in rural areas (X = 3.88; SD = .47) was not significant [t (994) = -1.570, P > .05].We found that nurses regard online learning opportunities as suitable for their working conditions and needs. Nurses should be provided with continued training through online learning alternatives, regardless of age, working experience or area of residence.Professionals in developed countries need training to become more qualified and to adapt to changing work conditions. Most of them prefer to get online training [1]. Online learning, which provides learners with a variety of benefits such as convenience, flexibility and opportunities to work collaboratively, has considerable potential for nursing continuing education.Online nursing continuing education provides Registered Nurses (RNs) with many advantages compared with face-to-face programs. First, it is difficult for nurses to return to school and to become students after a long break. It may also be challenging because of conflicting work schedules, personal responsibilities, and
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