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Search Results: 1 - 8 of 8 matches for " Schteingart "
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La Investigación urbana en América Latina
Martha Schteingart
Papeles de población , 2000,
Abstract: En este trabajo se hace un balance de los caminos recorridos en el campo de la investigación urbana en la mayor parte de los países de América Latina, con el fin de establecer algunos criterios básicos para formular una agenda de investigación para el futuro próximo. El trabajo "basado en una serie de estudios realizados en el marco del proyecto internacional Iniciativa Global para la Investigación Urbana (GURI, por sus siglas en inglés) y aplicados en tres subregiones" hace un recuento del inicio y evolución de la investigación urbana en cada subregión; desarrolla aspectos como las perspectivas teóricas de la investigación urbana, los temas investigados, las disciplinas involucradas y las estructuras institucionales de apoyo a la investigación, poniendo énfasis, además, en el análisis comparativo de las subregiones (México-Colombia y Centroamérica; Brasil y Venezuela; los países andinos y del Cono Sur) y en la importancia de los aspectos político-institucionales en el desarrollo de la investigación.
Aspectos conseptuales y metodológicos en estudios urbano-ambientales
Marhta Schteingart
Estudios Demográficos y Urbanos , 2000,
Abstract:
Problemas y políticas urbanas en América Latina. Certidumbres y falacias
Marhta Schteingart
Estudios Demográficos y Urbanos , 2007,
Abstract:
Rese a de "La pobreza en México y el mundo. Realidades y desafíos" de Julio Boltvinik y Araceli Damián (coords.)
Marhta Schteingart
Estudios Demográficos y Urbanos , 2006,
Abstract:
Rese a de "La construcción social y política del medio ambiente" de José Luis Lezama
Marhta Schteingart
Estudios Demográficos y Urbanos , 2005,
Abstract:
Conventional and novel strategies in the treatment of adrenocortical cancer
Schteingart, D.E.;
Brazilian Journal of Medical and Biological Research , 2000, DOI: 10.1590/S0100-879X2000001000009
Abstract: adrenocortical carcinoma is a highly malignant neoplasm with an incidence of two per million people per year. several treatment strategies have resulted in temporary or partial tumor regression but very few cases have attained long survival. surgical resection of the primary tumor and metastases is most effective. several chemotherapeutic protocols have been employed with variable success. mitotane (o,p'-ddd) is an adrenalytic drug effective in inducing a tumor response in 33% of patients treated. mitotane requires metabolic transformation for therapeutic action. tumors may vary in their ability to metabolize mitotane and the ability of tumors to transform mitotane may predict the clinical response to the drug. preliminary data show a possible correlation between metabolic activity of neoplastic adrenocortical tissue and response to mitotane. we have attempted to develop mitotane analogs with enhanced adrenalytic effect. compared to mitotane, a di-chloro compound, the bromo-chloro and di-bromo analogs appear to have a greater effect. future approaches to the treatment of adrenocortical carcinoma are likely to be based on blocking or reversing the biological mechanisms of tumorigenesis. angiogenic and chemotactic mechanisms may play a role in adrenal tumor growth and inhibition of these mechanisms may result in inhibition of tumor growth. new mitotane analogs with greater adrenalytic potential could be a promising approach to developing more effective and selective therapies for adrenal cancer. alternative approaches should attempt to suppress tumor growth by means of compounds with anti-angiogenic and anti-chemotactic activity.
Expansión urbana, protección ambiental y actores sociales en la Ciudad de México
Martha Schteingart,Clara Salazar
Estudios Demográficos y Urbanos , 2003,
Abstract:
Conventional and novel strategies in the treatment of adrenocortical cancer
Schteingart D.E.
Brazilian Journal of Medical and Biological Research , 2000,
Abstract: Adrenocortical carcinoma is a highly malignant neoplasm with an incidence of two per million people per year. Several treatment strategies have resulted in temporary or partial tumor regression but very few cases have attained long survival. Surgical resection of the primary tumor and metastases is most effective. Several chemotherapeutic protocols have been employed with variable success. Mitotane (o,p'-DDD) is an adrenalytic drug effective in inducing a tumor response in 33% of patients treated. Mitotane requires metabolic transformation for therapeutic action. Tumors may vary in their ability to metabolize mitotane and the ability of tumors to transform mitotane may predict the clinical response to the drug. Preliminary data show a possible correlation between metabolic activity of neoplastic adrenocortical tissue and response to mitotane. We have attempted to develop mitotane analogs with enhanced adrenalytic effect. Compared to mitotane, a di-chloro compound, the bromo-chloro and di-bromo analogs appear to have a greater effect. Future approaches to the treatment of adrenocortical carcinoma are likely to be based on blocking or reversing the biological mechanisms of tumorigenesis. Angiogenic and chemotactic mechanisms may play a role in adrenal tumor growth and inhibition of these mechanisms may result in inhibition of tumor growth. New mitotane analogs with greater adrenalytic potential could be a promising approach to developing more effective and selective therapies for adrenal cancer. Alternative approaches should attempt to suppress tumor growth by means of compounds with anti-angiogenic and anti-chemotactic activity.
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