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Search Results: 1 - 10 of 40 matches for " Schoenberg "
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Discussion of "Estimating the historical and future probabilities of large terrorist events" by Aaron Clauset and Ryan Woodard
Frederic Paik Schoenberg
Statistics , 2014, DOI: 10.1214/13-AOAS614E
Abstract: Discussion of "Estimating the historical and future probabilities of large terrorist events" by Aaron Clauset and Ryan Woodard [arXiv:1209.0089].
Factors Associated with Increases in Glucose Levels in the Perioperative Period in Non-Diabetic Patients  [PDF]
Vasanti Tilak,Catherine Schoenberg,Alejandro F. Castro III,Manasee Sant
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.33042
Abstract: Background: Blood glucose levels are elevated during the perioperative period as a result of the neuro-endocrine response to the stress of surgery. In nondiabetic patients, blood glucose levels are not a part of routine preoperative testing nor are they monitored during surgery or in the post anesthesia care unit (PACU). We measured blood glucose levels in nondiabetic patients during the perioperative period to identify how many patients had high glucose levels and what factors were associated with increases in blood glucose levels. Methods: This prospective observational study included two hundred and ninety five nondiabetic patients between the ages of 18 and 80 years, undergoing elective noncardiac surgery. Blood glucose levels were measured preoperatively and at frequent, predetermined intervals during surgery and in the PACU. Patient characteristics, surgical and anesthetic factors, and pain scores in the PACU were recorded, as were postoperative complications. Results: Forty nine percent (49%) of the patients had maximum intraoperative glucose levels of 126 mg/dl or higher and fifty three percent (53%) had maximum postoperative glucose levels of 126 mg/dl or higher. Preoperative glucose levels, family history of diabetes and amount of blood loss were statistically significantly associated with both max-intra-op and max-post-op glucose levels. Additionally, blood administration, surgery duration and race were significantly associated with max-intra-op glucose levels, while amount of intravenous fluids and sex were significantly associated with max-post-op glucose levels. Conclusion: A large number of nondiabetic patients in our study had maximum glucose levels >126 mg/dl in the perioperative period. Certain patient characteristics, as well as surgical/anesthetic factors, were associated with increases in the glucose levels. More studies are indicated to determine which patients may benefit from glucose monitoring in the perioperative period.
Factors Associated with Increases in Glucose Levels in the Perioperative Period in Non-Diabetic Patients  [PDF]
Vasanti Tilak, Catherine Schoenberg, Alejandro F. Castro III, Manasee Sant
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.33042
Abstract:

Background: Blood glucose levels are elevated during the perioperative period as a result of the neuro-endocrine response to the stress of surgery. In nondiabetic patients, blood glucose levels are not a part of routine preoperative testing nor are they monitored during surgery or in the post anesthesia care unit (PACU). We measured blood glucose levels in nondiabetic patients during the perioperative period to identify how many patients had high glucose levels and what factors were associated with increases in blood glucose levels. Methods: This prospective observational study included two hundred and ninety five nondiabetic patients between the ages of 18 and 80 years, undergoing elective noncardiac surgery. Blood glucose levels were measured preoperatively and at frequent, predetermined intervals during surgery and in the PACU. Patient characteristics, surgical and anesthetic factors, and pain scores in the PACU were recorded, as were postoperative complications. Results: Forty nine percent (49%) of the patients had maximum intraoperative glucose levels of 126 mg/dl or higher and fifty three percent (53%) had maximum postoperative glucose levels of 126 mg/dl or higher. Preoperative glucose levels, family history of diabetes and amount of blood loss were statistically significantly associated with both max-intra-op and max-post-op glucose levels. Additionally, blood administration, surgery duration and race were significantly associated with max-intra-op glucose levels, while amount of intravenous fluids and sex were significantly associated with max-post-op glucose levels. Conclusion: A large number of nondiabetic patients in our study had maximum glucose levels >126 mg/dl in the perioperative period. Certain patient characteristics, as well as surgical/anesthetic factors,

Point process modeling of wildfire hazard in Los Angeles County, California
Haiyong Xu,Frederic Paik Schoenberg
Statistics , 2011, DOI: 10.1214/10-AOAS401
Abstract: The Burning Index (BI) produced daily by the United States government's National Fire Danger Rating System is commonly used in forecasting the hazard of wildfire activity in the United States. However, recent evaluations have shown the BI to be less effective at predicting wildfires in Los Angeles County, compared to simple point process models incorporating similar meteorological information. Here, we explore the forecasting power of a suite of more complex point process models that use seasonal wildfire trends, daily and lagged weather variables, and historical spatial burn patterns as covariates, and that interpolate the records from different weather stations. Results are compared with models using only the BI. The performance of each model is compared by Akaike Information Criterion (AIC), as well as by the power in predicting wildfires in the historical data set and residual analysis. We find that multiplicative models that directly use weather variables offer substantial improvement in fit compared to models using only the BI, and, in particular, models where a distinct spatial bandwidth parameter is estimated for each weather station appear to offer substantially improved fit.
Assessment of Point Process Models for Earthquake Forecasting
Andrew Bray,Frederic Paik Schoenberg
Statistics , 2013, DOI: 10.1214/13-STS440
Abstract: Models for forecasting earthquakes are currently tested prospectively in well-organized testing centers, using data collected after the models and their parameters are completely specified. The extent to which these models agree with the data is typically assessed using a variety of numerical tests, which unfortunately have low power and may be misleading for model comparison purposes. Promising alternatives exist, especially residual methods such as super-thinning and Voronoi residuals. This article reviews some of these tests and residual methods for determining the goodness of fit of earthquake forecasting models.
Impact of Weather Covariates on Wildfire in Tanjung Puting National Park
Esa Eslami,Akane Nishimura,Frederic Paik Schoenberg
International Journal of Forestry Research , 2009, DOI: 10.1155/2009/270387
Abstract: This paper explores wildfire modeling based on meteorological variables for Tanjung Puting National Park, located on the island of Borneo. A separable model is developed for predicting daily wildfire burn area using variables such as temperature, sea level pressure, humidity, precipitation, visibility, and wind speed. Each component in the model is estimated using kernel smoothing and maximum likelihood methods. The data are shown to be largely compatible with the separable model, suggesting that the relationship between wildfire burn area and any of these weather variables in particular does not appear to change significantly depending on the values of the other weather variables. The analysis appears to confirm the findings of previous studies on wildfire in Southern California which indicate that wildfire hazard may be suitably estimated using a simple multiplicative model where the impact of each weather covariate is estimated separately.
3D raytracing through homogeneous anisotropic media with smooth interfaces
Costa, Jessé;Schoenberg, Michael;Urban, Jaime;
Revista Brasileira de Geofísica , 2002, DOI: 10.1590/S0102-261X2002000300003
Abstract: two-point raytracing problem is solved for events in a piecewise homogeneous and laterally varying 3d anisotropic media by continuation techniques. in conjunction with the shooting method the algorithm can be used for computation of qp, qs1, and qs2 events. the algorithm has the same performance and robustness as previous implementations of the continuation method for tracing rays in isotropic models. routines based on our algorithm have several useful applications. first, an efficient forward problem solver for traveltime inversion of elastic parameters in the presence of anisotropy. second, newton-raphson iterations during two-point raytracing produce wavefront attributes, slowness and wavefront curvature. these attributes allows the computation of geometrical spreading and second order approximations for traveltimes. therefore it can be used to investigate the effects of anisotropy on crs, in simple velocity models.
A Statistical Analysis of Santa Barbara Ambulance Response in 2006: Performance Under Load
Chang, Joshua C,Schoenberg, Frederic P
Western Journal of Emergency Medicine : Integrating Emergency Care with Population Health , 2009,
Abstract: Ambulance response times in Santa Barbara County for 2006 are analyzed using point process techniques, including kernel intensity estimates and K-functions. Clusters of calls result in significantly higher response times, and this effect is quantified. In particular, calls preceded by other calls within 20 km and within the previous hour are significantly more likely to result in violations. This effect appears to be especially pronounced within semi-rural neighborhoods.[WestJEM. 2009;10:42-47.]
The Cytoplasmic Capping Complex Assembles on Adapter Protein Nck1 Bound to the Proline-Rich C-Terminus of Mammalian Capping Enzyme
Chandrama Mukherjee,Baskar Bakthavachalu,Daniel R. Schoenberg
PLOS Biology , 2014, DOI: 10.1371/journal.pbio.1001933
Abstract: Cytoplasmic capping is catalyzed by a complex that contains capping enzyme (CE) and a kinase that converts RNA with a 5′-monophosphate end to a 5′ diphosphate for subsequent addition of guanylic acid (GMP). We identify the proline-rich C-terminus as a new domain of CE that is required for its participation in cytoplasmic capping, and show the cytoplasmic capping complex assembles on Nck1, an adapter protein with functions in translation and tyrosine kinase signaling. Binding is specific to Nck1 and is independent of RNA. We show by sedimentation and gel filtration that Nck1 and CE are together in a larger complex, that the complex can assemble in vitro on recombinant Nck1, and Nck1 knockdown disrupts the integrity of the complex. CE and the 5′ kinase are juxtaposed by binding to the adjacent domains of Nck1, and cap homeostasis is inhibited by Nck1 with inactivating mutations in each of these domains. These results identify a new domain of CE that is specific to its function in cytoplasmic capping, and a new role for Nck1 in regulating gene expression through its role as the scaffold for assembly of the cytoplasmic capping complex.
Placement of an aortomonoiliac stent graft without femorofemoral revascularization in endovascular aneurysm repair: a case report
Michael Keese, Marco Niedergethmann, Stefan Schoenberg, Steffen Diehl
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-365
Abstract: We report the case of an 80-year-old Caucasian man who presented with an unusually configured, symptomatic infrarenal aortic aneurysm. His aneurysm showed an erosion of the fourth lumbar vertebra and a severely arteriosclerotic pelvic axis. A high thigh amputation of his right leg had been performed 15 months previously. On his right side, occlusion of his external iliac artery, common femoral artery, and deep femoral artery had occurred. His aneurysm was treated by a left-sided aortomonoiliac stent graft without femorofemoral revascularization, resulting in occlusions of both internal iliac arteries. No ischemic symptoms appeared, although perfusion of his right side was maintained only over epigastric collaterals.The placement of aortomonoiliac stent grafts for endovascular treatment of infrarenal aortic aneurysms without contralateral revascularization is a feasible treatment option in isolated cases. In this report, access problems and revascularization options in endovascular aneurysm repair are discussed.The trend in the care of patients with an infrarenal aortic aneurysm is to administer endovascular treatment when feasible. This is because grade 1 evidence indicates a decrease in postoperative morbidity, a shorter hospital stay, a quicker recovery time, and a significantly lower early postoperative mortality when endovascular aneurysm repair (EVAR) is chosen as treatment [1]. However, EVAR does not improve long-term survival and has been associated with a need for continued surveillance and reinterventions at substantially increased costs. Thus, especially in high-risk patients, the emphasis has shifted toward improving patient fitness before considering any treatment of aortic aneurysms. Especially when patients present with a symptomatic aortic aneurysm or (contained) rupture, the question of whether an endovascular intervention is advisable arises. Erosion of a vertebra is considered a radiological sign of a pending rupture [2]. Survival statistics indica
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