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Search Results: 1 - 10 of 1644 matches for " Saxena Rohit "
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Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)—A Brief Review  [PDF]
Mukesh Patil, Anita Ganger, Rohit Saxena
Open Journal of Ophthalmology (OJOph) , 2016, DOI: 10.4236/ojoph.2016.63022
Abstract: Ischemic optic neuropathies could be a result of inflammatory and non inflammatory small vessel disease and have been classified as arteritic and non-arteritic anterior ischemic optic neuropathy respectively. This review has been intended to elucidate the epidemiology, etiology, pathogenesis, clinical picture and management of NAION and the literature search was completed using the published data in Pubmed, Medline, and Ovid over the last five decades.
Smooth Cepstrum Calculation Using Modified Bartlett Hanning Window
Prof. Rajiv Saxena,Rohit Pandey
International Journal of Electronics and Computer Science Engineering , 2012,
Abstract: Cepstrum is an algorithm for analyzing the speech signals in frequency domain. This is conventional method of fundamental peak picking i.e. fundamental frequency or pitch. For a speech signal it is necessary to identify the fundamental frequency correctly in order to have robust system for speaker identification and verification. Using this approach two algorithms has been proposed using Hamming window and Modified Bartlett Hanning Window. These algorithms involve the filtering called liftering after converting the speech sample to Cepstrum domain (Quefrency domain). The utility of using filtering in cepstrum domain has been analyzed as window functions play vital role in deciding the fundamental peak of the speech sample. Gross Pitch Estimation Error has been calculated with smooth cepstrum and smooth cepstrum with autocorrelation in order to calculate false acceptance and rejection rate for two speakers respectively.
Bilateral neuro-retinitis following chick embryo cell anti-rabies vaccination – a case report
Rohit Saxena, Harinder Sethi, Harminder Rai, Vimla Menon
BMC Ophthalmology , 2005, DOI: 10.1186/1471-2415-5-20
Abstract: We report the case of a 56 year old male who developed bilateral neuro-retinitis following three injections of antirabies vaccine prepared from the chick embryo.The chick embryo cell antirabies vaccine can cause bilateral neuroretinits which has not been reported previously.The Optic nerve is rarely involved after sheep brain anti-rabies vaccination. Neurological complications are usually seen with sheep brain vaccines but can be rarely seen after chick embryo cell vaccines [1]. The main cause in such cases is presumed to be the antigenic cerebral tissue used in the preparation of sheep brain vaccine [2-5]. We report the case of a 56 year old male who developed bilateral neuro-retinitis following three injections of antirabies vaccine prepared from the chick embryo. Retrobular neuritis and papillitis following sheep brain antirabies vaccine have been reported [6-11]. The present report describes a case with bilateral neuroretinitis after chick embryo antirabies vaccine, which to best of our knowledge has not been reported earlier.A 56 year old male presented with complaint of acute onset painless diminution of vision in the right eye of 3 days duration followed by similar complaint in left eye after 1 day which deteriorated over the next 2 days. This was associated with headache and pain on ocular movements. There was a history of being bitten by a stray dog 8 days before the visual symptoms, and the patient had received three injections of chick embryo cell anti-rabies vaccine (Rabipur, Hoeshst Marion Roussel) on day 0, 3 and 7 after the dog bite. He developed these symptoms after the third injection. There was no history of any other ocular or systemic problems.The general physical examination was within normal limits. The best-corrected visual acuity was 6/60 in the right and 6/24 in the left eye. IOP was 16 mm of Hg by applanation tonometry. Anterior segment examination using slitlamp was normal. Fundoscopy using + 90 D revealed hyperemic optic disc with blurred
Classification of amblyopia
Menon Vimla,Chaudhuri Zia,Saxena Rohit,Gill Kulwant
Indian Journal of Ophthalmology , 2006,
Hand held digital camera for digital video recording in ophthalmic surgery
Sinha Ankur,Saxena Rohit,Sethi Harinder,Turaka Kiran
Indian Journal of Ophthalmology , 2006,
Advances in pharmacological strategies for the prevention of cataract development
Gupta S,Selvan V,Agrawal S,Saxena Rohit
Indian Journal of Ophthalmology , 2009,
Abstract: Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo , to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources.
Authors′ reply
Bhola Rahul,Saxena Rohit,Sethi Harinder,Sharma Pradeep
Indian Journal of Ophthalmology , 2006,
A rare case of orbital apex syndrome with herpes zoster ophthalmicus in a human immunodeficiency virus-positive patient
Saxena Rohit,Phuljhele Swati,Aalok Lalit,Sinha Ankur
Indian Journal of Ophthalmology , 2010,
Abstract: We report a rare instance of favorable outcome in orbital apex syndrome secondary to herpes zoster ophthalmicus (HZO) in a human immunodeficiency virus (HIV)-positive patient. The patient complained of pain and decrease in vision in one eye (20/640) for 2 weeks accompanied with swelling, inability to open eye, and rashes around the periocular area and forehead. The presence of complete ophthalmoplegia, ptosis, relative afferent pupillary defect, and anterior uveitis with decreased corneal sensation prompted a diagnosis of HZO with orbital apex syndrome. The enzyme-linked immunosorbent assay test and a low CD4 count confirmed HIV. Highly active antiretroviral therapy (HAART), systemic acyclovir, and systemic steroids were started. Visual acuity and uveitis improved within 10 days. By the end of the fourth week, ocular motility also recovered and the final visual acuity was 20/25. We highlight the role of HAART, used in conjunction with systemic steroid and acyclovir therapy, in improving the outcome.
Management of optic neuritis
Menon Vimla,Saxena Rohit,Misra Ruby,Phuljhele Swati
Indian Journal of Ophthalmology , 2011,
Abstract: Optic neuritis is an inflammatory condition of the optic nerve characterized by a sudden onset of unilateral visual loss, usually affecting young females. Demyelination associated with multiple sclerosis (MS) is the most common cause in regions where MS is prevalent; while in other places, there are a substantial proportion of cases where infective or autoimmune causes are seen. Optic Neuritis Treatment Trial (ONTT) was the first major study that provided information on the natural history, role of steroids in treatment and risk of development of MS. Subsequently, numerous clinical trials have evaluated different modalities of management of optic neuritis and MS. The Controlled High-Risk Subjects Avonex Multiple Sclerosis Prevention Study (CHAMPS); the Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis (PRISMS) Trial; and, most recently, the Betaferon in Newly Emerging Multiple Sclerosis for Initial Treatment (BENEFIT) Study have provided large amount of information on the natural history of optic neuritis and management options available. However, due to the low prevalence of MS reported in Asian studies, high cost of therapy and indefinite time period of treatment, it may not be cost effective to start interferon therapy in most cases.
Profile of amblyopia in a hospital referral practice
Menon Vimla,Chaudhuri Zia,Saxena Rohit,Gill Kulwant
Indian Journal of Ophthalmology , 2005,
Abstract: Objective: Evaluation of the clinical profile and distribution of different sub-types of amblyopia in a referral eye hospital in India. Methods: This was a prospective hospital-based observational study, evaluating the clinical profile of patients with amblyopia presenting to a referral strabismology practice. The examination included assessment of the visual acuity, the refractive status, the fixation pattern, the grade of binocularity, and evaluation of the associated strabismus, if any before treatment was started. Results: The average age of the patients at presentation was 7.97±6.18 years with 81 out of 683 patients (11.8%) presenting above the age of 20 years. The best-corrected visual acuity (BCVA) was less than 6/60 in the amblyopic eye in 121 out of 733 eyes (16.5%). Strabismic amblyopia was the most common sub-type of amblyopia seen (274/733 eyes, 37.38%). Though patients with anisometropic amblyopia presented at a later age (average of 10.03±6.92 years), they had better visual acuity, binocular functions, and centricity of fixation at all ages, relative to other sub-types of amblyopia. The BCVA did not show any co-relation with the age of presentation [co-relation co-efficient (CF) of 0.074], refractive status of the amblyopic eye (CF of 0.078), the type of amblyopia (CF of 0.196), or the type of strabismus present (CF of 0.079). However, a very significant co-relation was seen between the BCVA and the fixation pattern of the amblyopic eye (CF of 0.817). Conclusions: Lack of knowledge and awareness about amblyopia and its appropriate timely management has been the main cause for the late presentations and significant visual impairment associated with the condition.
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