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SKIN CARE IN AYURVEDA: A LITERARY REVIEW
Kumar Sarvesh,Palbag Satadru,Maurya Santosh Kumar,Kumar Dileep
International Research Journal of Pharmacy , 2013, DOI: 10.7897/2230-8407.04301
Abstract: Ayurvedic cosmeceuticals dates back to the Indus valley civilization and is being used in human society from ancient time. It is now gaining importance in the beautification and to cure the skin ailments. In last 3-4 decades the use of cosmetics has increased exponentially not only among female but also in male population and play an important role in the FMCG sector. In the ancient classical texts of Ayurveda there are several references of numerous medicinal plants and mode of applications of their processed formulation for enhancing complexion, treating acne, treating dark patches, curing boils and carbuncles, etc. Consideration in this field can be helpful in making the herbs more acceptable, precious, life saving and economy promoter for the mankind. This review made a humble effort to make a monograph of ayurvedic plants that were mentioned by ayurvedic luminaries in the field of skincare.
QUALITATIVE EVALUATION OF MARKETED AYURVEDIC RED TOOTH POWDER BY NAMBURI PHASED SPOT TEST
Satadru Palbag,Varun Kumar Singh,Narendra Kumar Singh,D.N.S. Gautam
International Research Journal of Pharmacy , 2013, DOI: 10.7897/2230-8407.04324
Abstract: Simple and precise quality control analysis of consumer goods is the goal of rising FMCG sector. Ayurvedic red tooth powders are one of the most popular FMCG products in today’s market. The main ingredient (≥80%) of these red tooth powders is Swarna gairik (Red Hematite), thus the qualitative evaluation of red tooth powder can be performed by analysis of Swarna gairik. Objective of present study is to develop a simple yet precise method for the quality evaluation of Ayurvedic red tooth powders. Three marketed samples of red tooth powders S-1, S-2 and S-3 were evaluated by Namburi phased spot test against a control sample C. The variation of color and pattern of the spots were carefully evaluated at three distinct time phases. There were marked differences among the color and pattern of the spots for all the three samples when compared with the control, C. Study revealed that S-1 contains standard Swarna gairik whereas S-2 and S-3 contains spurious Swarna gairik. We concluded that the NST is a simple and dependable technique for the evaluation of Ayurvedic red tooth powder.
Numb chin syndrome as a manifestation of metastatic squamous cell carcinoma of esophagus
Narendra H,Ray Satadru
Journal of Cancer Research and Therapeutics , 2009,
Abstract: Numb chin syndrome (NCS) is a sensory neuropathy presenting with numbness of the chin in the distribution of the mental nerve and the branches of the mandibular division of the trigeminal nerve. Though it can be caused by a benign process, NCS should be regarded as being due to malignancy until proven otherwise. Among the malignancies that cause NCS the most common are breast cancer, prostate cancer, and lymphoreticular malignancy. In squamous cell carcinoma (SCC) of the esophagus, spread to the mandible is a rare and often late event. An often overlooked clinical sign in mandibular metastases is hypoesthesia or paresthesia over the peripheral distribution of the inferior alveolar nerve/mental nerve; this sign has been referred to in the literature as NCS or numb lip syndrome or mental nerve neuropathy. Rarely, this may be the first presentation of a disseminated malignancy. Prognosis is usually poor. The discovery of this symptom should alert the clinician to the possibility of disseminated disease. In this article we report a rare case of metastatic SCC of the esophagus in a 40-year-old male patient who presented with NCS. We also review the mechanism, causes, and evaluation of NCS.
Malignant extrarenal rhabdoid tumor of the vulva in an adult
Narendra H,Ray Satadru,Rao Lakshmi,Geetha V
Journal of Cancer Research and Therapeutics , 2010,
Abstract: Sarcomas of the vulva account for only 1-3% of all vulvar malignancies. Most common vulvar sarcomas are leiomyosarcomas, malignant fibrohistiocytomas, and aggressive angiomyxomas. Malignant rhabdoid tumor (MRT) of the kidney is a distinctive clinicopathological entity that is recognized as a highly aggressive renal tumor of childhood. Extrarenal malignant rhabdoid tumors have been proposed to exist at several sites, including soft parts. MRT of the vulva is a rare and very aggressive neoplasm. Median survival reported in other studies is 9 months. Only 10 cases have been reported thus far in the English literature. We are reporting the 11 th case who remains disease free 30 months following surgery and radiotherapy till the time of reporting.
Emergent Cosmology Revisited
Satadru Bag,Varun Sahni,Yuri Shtanov,Sanil Unnikrishnan
Physics , 2014, DOI: 10.1088/1475-7516/2014/07/034
Abstract: We explore the possibility of emergent cosmology using the effective potential formalism. We discover new models of emergent cosmology which satisfy the constraints posed by the cosmic microwave background (CMB). We demonstrate that, within the framework of modified gravity, the emergent scenario can arise in a universe which is spatially open/closed. By contrast, in general relativity (GR) emergent cosmology arises from a spatially closed past-eternal Einstein Static Universe (ESU). In GR the ESU is unstable, which creates fine tuning problems for emergent cosmology. However, modified gravity models including Braneworld models, Loop Quantum Cosmology (LQC) and Asymptotically Free Gravity result in a stable ESU. Consequently, in these models emergent cosmology arises from a larger class of initial conditions including those in which the universe eternally oscillates about the ESU fixed point. We demonstrate that such an oscillating universe is necessarily accompanied by graviton production. For a large region in parameter space graviton production is enhanced through a parametric resonance, casting serious doubts as to whether this emergent scenario can be past-eternal.
High-Fidelity Tissue Engineering of Patient-Specific Auricles for Reconstruction of Pediatric Microtia and Other Auricular Deformities
Alyssa J. Reiffel, Concepcion Kafka, Karina A. Hernandez, Samantha Popa, Justin L. Perez, Sherry Zhou, Satadru Pramanik, Bryan N. Brown, Won Seuk Ryu, Lawrence J. Bonassar, Jason A. Spector
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0056506
Abstract: Introduction Autologous techniques for the reconstruction of pediatric microtia often result in suboptimal aesthetic outcomes and morbidity at the costal cartilage donor site. We therefore sought to combine digital photogrammetry with CAD/CAM techniques to develop collagen type I hydrogel scaffolds and their respective molds that would precisely mimic the normal anatomy of the patient-specific external ear as well as recapitulate the complex biomechanical properties of native auricular elastic cartilage while avoiding the morbidity of traditional autologous reconstructions. Methods Three-dimensional structures of normal pediatric ears were digitized and converted to virtual solids for mold design. Image-based synthetic reconstructions of these ears were fabricated from collagen type I hydrogels. Half were seeded with bovine auricular chondrocytes. Cellular and acellular constructs were implanted subcutaneously in the dorsa of nude rats and harvested after 1 and 3 months. Results Gross inspection revealed that acellular implants had significantly decreased in size by 1 month. Cellular constructs retained their contour/projection from the animals' dorsa, even after 3 months. Post-harvest weight of cellular constructs was significantly greater than that of acellular constructs after 1 and 3 months. Safranin O-staining revealed that cellular constructs demonstrated evidence of a self-assembled perichondrial layer and copious neocartilage deposition. Verhoeff staining of 1 month cellular constructs revealed de novo elastic cartilage deposition, which was even more extensive and robust after 3 months. The equilibrium modulus and hydraulic permeability of cellular constructs were not significantly different from native bovine auricular cartilage after 3 months. Conclusions We have developed high-fidelity, biocompatible, patient-specific tissue-engineered constructs for auricular reconstruction which largely mimic the native auricle both biomechanically and histologically, even after an extended period of implantation. This strategy holds immense potential for durable patient-specific tissue-engineered anatomically proper auricular reconstructions in the future.
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