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Transperineal bulboprostatic anastomotic repair of pelvic fracture urethral distraction defect and role of ancillary maneuver: A retrospective study in 172 patients
Singh Santosh,Pawar Devendra,Khandelwal Atul,Jagmohan
Urology Annals , 2010,
Abstract: Objective: We present our experience with transperineal bulboprostatic anastomosis procedure and compare the results with age of patients, length of urethral stricture, effect of previous treatment and need for ancillary procedures. Materials and Methods: We retrospectively reviewed the outcome of 172 patients who underwent perineal urethroplasty procedure for traumatic stricture in our institute. Simple perineal anastomosis was done in 92 patients. Perineal anastomosis and corporal separation were done in 52 patients. Perineal anastomosis with inferior pubectomy was done in 25 patients. Perineal anastomosis with rerouting was done in three patients. Age, prior treatment, length of stricture, and ancillary techniques required during reconstruction were compiled. The clinical outcome was considered as failure when any postoperative instrumentation was needed. Results: Out of 172 cases that underwent transperineal urethroplasty procedure, 157 (91.28%) were successful. Simple perineal urethroplasty procedure showed a success rate of 93.4%, perineal anastomosis with separation of corporal bodies had a success rate of 90.4%, perineal anastomosis with inferior pubectomy had a success rate of 88% and perineal anastomosis with rerouting of urethra around the corpora had a success rate of 66.7%. Conclusion: The success rate of delayed progressive perineal urethroplasty procedure for post-traumatic stricture urethra is excellent and majority of the failures occurs in prepubescent boys and in those undergoing secondary repair.
Synthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1H-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives  [PDF]
Shrikrishna D. Tupare, Satish A. Dake, Santosh V. Nalage, Sidhanath V. Bhosale, Rajita D. Ingle, Rajendra P. Pawar
International Journal of Organic Chemistry (IJOC) , 2012, DOI: 10.4236/ijoc.2012.24051
Abstract: Pyrazoles are important nitrogen containing 5-membered heterocyclic compounds. Numerous pyrazoline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. Several 1,3,5-Triphenyl-1H-pyrazole containing 6-aminopyridazin-3(2H)-one derivatives has been synthesized. These new compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore biological screening of novel compounds has been also done.
Pawan P. Rathod,Santosh S. Pawar,Narendra A. Manwar
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: The objective of the present study is to explore the Diversity and Abundance of dragonflies and damselflies (Order – odonata, Class Insecta, phylum Arthopoda) in agro ecosystems around Amravati city in monsoon season (July 2012 to October 2012). Odonata fauna of agro ecosystem for present study was investigated, total 31 species belonging to six families of dragonflies and damselflies (order - odonata) were recorded, in which the most abundant family was Lebellulidae followed by Coenagrionidae, while Gomphidae, Lestidae Aeshnidae, Platycnemididae families were least abundant. Libellulidae family represents 17 species, coenagrionidae represents 9 species, gomphidae represents 2 while Aeshnidae, Platycnemididae and Lestidae were with one species each. We also calculated the Species diversity (H) and Evenness (E) which is 3.012 and 0.877 respectively. From above study we conclude that the present study area is rich in dragonflies and damselflies fauna in monsoon season
The efficacy of tamsulosin in lower ureteral calculi
Griwan M,Singh Santosh,Paul Himanshu,Pawar Devendra
Urology Annals , 2010,
Abstract: Context: There has been a paradigm shift in the management of ureteral calculi in the last decade with the introduction of new less invasive methods, such as ureterorenoscopy and extracorporeal shock wave lithotripsy (ESWL). Aims: Recent studies have reported excellent results with medical expulsive therapy (MET) for distal ureteral calculi, both in terms of stone expulsion and control of ureteral colic pain. Settings and Design: We conducted a comparative study in between watchful waiting and MET with tamsulosin. Materials and Methods: We conducted a comparative study in between watchful waiting (Group I) and MET with tamsulosin (Group II) in 60 patients, with a follow up of 28 days. Statistical Analysis: Independent ′t′ test and chi-square test. Results: Group II showed a statistically significant advantage in terms of the stone expulsion rate. The mean number of episodes of pain, mean days to stone expulsion and mean amount of analgesic dosage used were statistically significantly lower in Group II (P value is 0.007, 0.01 and 0.007, respectively) as compared to Group I. Conclusions: It is concluded that MET should be considered for uncomplicated distal ureteral calculi before ureteroscopy or extracorporeal lithotripsy. Tamsulosin has been found to increase and hasten stone expulsion rates, decrease acute attacks by acting as a spasmolytic, reduces mean days to stone expulsion and decreases analgesic dose usage.
Xanthogranulomatous cystitis: A rare clinical entity
Singh Santosh,Khandelwal Atul,Pawar Devendra,Sen Rajeev
Urology Annals , 2010,
Abstract: Xanthogranulomatous cystitis (XC) is a rare benign disease of unknown etiology. A case of XC in a 30-year-old male is presented due to sparcity of such case report in medical literature. Patient evaluation included clinical, biochemical and radiological studies before treatment. Histological study revealed the rare diagnosis. Patient was asymptomatic at eight weeks follow-up after treatment.
A Novel Idea of Using Digital Camera for Laparoscopy Training in Urology
Devendra S Pawar,Santosh K Singh,Shobha Benjwal,Indu Kumari
Urology Journal , 2010,
Fiber Bragg Grating Filter for Optical Communication: Applications and Overview
Santosh Pawar,Shubhada Kumbhaj,Pratima. Sen,Pranay Kumar Sen
International Journal of Advanced Electrical and Electronics Engineering , 2013,
Abstract: Recently, optical fiber Bragg grating have attracted a great deal of attention because of their importance in designing new devices to meet a need range of optical communication systems. An intense investigation of the possibility of using this optical device for all optical ultrafast applications is achieved by allowing their dielectric characteristics to be varied in such a way that a periodic perturbation of their refractive index along the length of the optical fiber will be formed. The coupled mode method, on the other hand, has been proven to be one of the most powerful analytical techniques that are usefully applied to a wide range of optical devices. In this paper, a coupled mode equations has been solved for fiber Bragg grating to analyze the grating structures that exhibit attractive optical properties that make them suitable for optical communication system as a wavelength filter. The paper also describes a simplified theoretical model to analyze the linear reflection characteristics of uniform fiber Bragg grating at low excitation intensity. The linear coupled mode theory has been adopted to calculate the reflectivity of the grating in the linear regime. We derived the solutions for both forward and backward propagating field amplitudes considering the propagation of a CW laser beam through the grating.
Pawar Prajakta,Deshpande Padmanabh,Gandhi Santosh,Bhavnani Vandana
International Research Journal of Pharmacy , 2012,
Abstract: A new simple high performance thin layer chromatography (HPTLC) method for determination of Cilnidipine and Telmisartan in combined dosage form has been developed and validated. The separation was carried out on Merck aluminium plates precoated with silica gel 60 F254 using Toluene: Methanol: Ethyl acetate (8: 2: 1, v/v/v) as the mobile phase, and detection was carried out at 260 nm. Results were linear in the range of 200-1200 ng/band for Cilnidipine and 800-4800 ng/band for Telmisartan. The method was successfully applied for the analysis of drugs in pharmaceutical formulation. Results of the analysis were validated statistically and by recovery studies.
Mr.Sohan S.Chitlange,Mr. Ajay S. Pawar,Mr.Hemant I. Pawar,Mr.Santosh S. Bhujbal
Pharmaceutical Reviews , 2006,
Abstract: Validation is establishing documented evidence, which provides high degreeassurance that a specific process will consistently produce a product meetingits predetermined specification and quality characteristics.Butvalidation itself does not improve process but assures that the process hasbeen properly developed and is under control.
Role of Tamsulosin in Clearance of Upper Ureteral Calculi After Extracorporeal Shock Wave Lithotripsy:A Randomized Controlled Trial
Santosh Kumar Singh,Devendra Singh Pawar,Mahavir Singh Griwan,Jag Mohan Indora
Urology Journal , 2011,
Abstract: PURPOSE: To evaluate the role of tamsulosin in stone clearance in patients with upper ureteral stone after extracorporeal shock wave lithotripsy (SWL). MATERIALS AND METHODS: This randomized controlled trial was performed on 117 patients with a single upper ureteral calculus undergoing SWL. The study group received 0.4 mg tamsulosin daily while the control group received hydration and analgesic on demand for a maximum of 3 months. Follow-up visits were performed at 1, 2, and 3 months after SWL. Efficiency of tamsulosin was evaluated in terms of success rate, time for expulsion of fragments, number of SWL sessions, incidence of steinstrasse, and pain intensity. RESULTS: The clearance rate after 1, 2, and 3 months were higher in tamsulosin group than the control group (85%, 89.8%, and 91.5% versus 70.6%, 79.3%, and 86.2%; P = .01, P = .11, and P = .34, respectively). The mean time for expulsion of the fragments was 26.78 ± 11.96 days and 31.28 ± 18.31 days in tamsulosin and control groups, respectively (P = .138). Steinstrasse developed in 8 patients in tamsulosin group and in 13 patients in control group (P = .167). Visual analogue scale pain score was 24.92 ± 7.57 in tamsulosin group and 41.81 ± 17.24 in control group (P = .000). CONCLUSION: Tamsulosin helps in clearance of upper ureteral stones after 1 month of SWL, particularly stones with size of 11 to 15 mm with lessrequirement of SWL sessions and analgesics.
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