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Search Results: 1 - 10 of 38820 matches for " Santiago Martínez-Jiménez "
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Imaging Manifestations of Mediastinal Fat Necrosis
Malay Y. Bhatt,Santiago Martínez-Jiménez,Melissa L. Rosado-de-Christenson,Kenneth R. Watson,Christopher M. Walker,Jeffrey R. Kunin
Case Reports in Radiology , 2013, DOI: 10.1155/2013/323579
Abstract: Mediastinal fat necrosis (MFN) or epipericardial fat necrosis, as it is commonly referred to in the literature, is a rare self-limiting cause of chest pain of unclear etiology. MFN affects previously healthy individuals who present with acute pleuritic chest pain. Characteristic computed tomography (CT) findings include a fat attenuation lesion with intrinsic and surrounding increased attenuation stranding. There is often associated thickening of the adjacent pericardium and/or pleural effusions. We present two cases of MFN manifesting as ovoid fat attenuation lesions demarcated by a soft tissue attenuation rim with intrinsic and surrounding soft tissue attenuation stranding and review the clinical and pathologic features of these lesions. Knowledge of the clinical presentation of patients with MFN and familiarity with the characteristic imaging findings of these lesions should allow radiologists to prospectively establish the correct diagnosis and suggest conservative management and follow-up. 1. Introduction Mediastinal fat necrosis (MFN) is a rare self-limiting cause of chest pain, with the first reported cases dating back to 1957 [1]. In the current literature, “epipericardial” or “epicardial” fat necrosis is the term used to identify this condition [2–4]. However, as the juxtapericardial mediastinal fat is characteristically affected, we propose that the term MFN is more appropriate given the anatomical location of the disease process. MFN classically affects previously healthy individuals who present with acute pleuritic chest pain that raises concern for an acute cardiopulmonary process including pulmonary thromboembolic and coronary artery diseases [1–12]. We present two cases of MFN and discuss their clinical, pathologic, and imaging findings. In both cases, the affected patients presented with severe chest pain and no associated physical examination findings or specific laboratory abnormalities. The presentation of acute pleuritic chest pain in association with CT findings of an ovoid juxtapericardial fat attenuation lesion with intrinsic and surrounding increased attenuation stranding, thickening of the adjacent pericardium, and resolution on follow-up imaging can be collectively used to establish the diagnosis [2]. Making the correct diagnosis prospectively mitigates unnecessary testing in favor of conservative management. 2. Case Reports Case 1. A 51-year-old man presented with dyspnea and left pleuritic chest pain that radiated to his back. His physical exam and laboratory tests were normal. PA and lateral chest radiographs showed a small
Comparative Study between D2EHPA and Cyanex 272 as Extractants of Mn(II) from a Leached Liquor Produced by Reductive Leaching of a Pyrolusite Ore with SO2  [PDF]
R. Pérez-Garibay, J. Martínez-Jiménez, A. Uribe-Salas, A. Martínez-Luévanos
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.49067
Abstract: This paper compares the efficiency of D2EHPA and Cyanex 272 to extract the divalent manganese cation from an actual leaching solution obtained by reductive leaching of a low-grade pyrolusite ore, using SO2 gas. The studied variables were the extractant concentration in the organic phase, the pH of the leached liquor and the volume ratio between organic phase and leached liquor. It was observed that D2EHPA is a better extractant than Cyanex272. Therefore, with the best experimental conditions found, both extractants reach a manganese recovery around 95% with five extraction stages conducted under the following conditions: 25?C, O/A = 2, 10% volume of extractant concentration in the organic phase, pH of the leached liquor before the mixing between 8 and 8.5, and one minute of mixing time for each extraction stage.
The Mexican Environmental Flow Standard: Scope, Application and Implementation  [PDF]
María Antonieta Gómez-Balandra, María del Pilar Salda?a-Fabela, Maricela Martínez-Jiménez
Journal of Environmental Protection (JEP) , 2014, DOI: 10.4236/jep.2014.51010
Abstract:

With the implementation of the Official Mexican Standard NOM-011-CONAGUA-2000 [1], the water balance of 730 basins has been calculated and its water availability agreement is published. This rule points out to allocate water for the environment only as an annual volume since methods for estimating environmental flows were not standardized in the country. For this reason, The Water Agency (CONAGUA) issued the standard NMX-AA-159-SCFI-2012 [2], to assess environmental flows needed both, at the strategic level in Integrated Water Resources Management (IWRM), or as part of the Environmental Impact Assessment (EIA) of large hydraulic projects. For over ten years, this standard was developed and finally published in September 2012 [3]. It explains different methods from hydrological to holistic approaches, with examples for the country. Its application will cover the urgent need to preserve water for ecosystems in watersheds with high ecological importance and low stress for water use. In this paper, an analysis of the environmental flow standard and examples of the suggested hydrological methods are presented. For its implementation, some steps are taking place, mainly establishing environmental water reserves and building capacities. In addition, environmental allocations are becoming a common practice for all water projects, as well as setting limits to hydrological alterations by hydroelectric dams. The standard promotes the use of technical integration tools to analyze the responses of ecosystems to changes in the flow regime and adaptive management under different scenarios of water use. Although the main steps have been taken, its implementation as mandatory rule will take time.

Cronobiología en anestesia epidural Obstétrica: Efecto de la noche sobre el índice de complicaciones
Martínez-Jiménez,F.; Guasch,E.; Blas,M. de; Gilsanz,F.;
Revista de la Sociedad Espa?ola del Dolor , 2006,
Abstract: introduction: sleep deprivation effects in vigilance, performance and complications have been previously studied in general population and in medical tasks too. results from these studies weren?t definitive. aim: our objective is to compare the number of complications during the epidural puncture itself, (haematic, paresthesias, accidental dural puncture and others) during the analgesia period (lateral, incomplete or imperfect analgesia, inefficacious, repuncture tax) and 24 hours after delivery, looking for late complications and to evaluate differences between day and night. we defined day from 9:00 to 21:59 h and night between 22:00 and 8:59h. patients and methods: we performed a computered data-base analysis on regional blocks for labour analgesia in a level 4 universitary hospital with a 24 hours epidural analgesia unit during 2 months. results: we have studied 1097 patients that resulted homogeneous in demographic and obstetric variables when we compared day versus night. the number of patients demanding analgesia didn?t show differences between day and night. we couldn?t find differences in the incidence of complications neither during the block performance nor in the incidence of incomplete, lateral analgesia or block failure. conclusions: it looks that workload or sleep deprivation don?t have so much influence over the complications taxes in a 24 hours labour analgesia unit. it could be due to the interest and stress of the medical activity.
Cronobiología en anestesia epidural Obstétrica: Efecto de la noche sobre el índice de complicaciones Cronobiology in obstetric epidural anesthesia: consequences of the sleep deprivation among anestresiologist in the complications rate
F. Martínez-Jiménez,E. Guasch,M. de Blas,F. Gilsanz
Revista de la Sociedad Espa?ola del Dolor , 2006,
Abstract: Introducción: Los efectos del trabajo continuado y nocturno sobre la atención y la incidencia de complicaciones en desarrollo habitual de las labores del médico han sido previamente estudiados, aunque con resultados poco concluyentes. Objetivo: Comparar la incidencia de complicaciones, durante la punción, en el curso del bloqueo, como consecuencia de una analgesia incompleta y evaluar las diferencias que existen entre el día y la noche definiendo día como el periodo entre 9:00 y 21:59 h y noche: de 22:00 a 8:59 h. Material y métodos: Hemos realizado un estudio de los bloqueos recogidos en nuestra base de datos informatizada de pacientes a quienes se practicó algún bloqueo central para analgesia del parto realizados en un hospital universitario de grado 4, con atención durante las 24 horas, durante un periodo de 2 meses. Resultados: Se ha estudiado un total de 1097 pacientes, homogéneas en su distribución (variables demográficas y obstétricas), entre el día y la noche. El número de pacientes a las que se les practica un bloqueo analgésico para trabajo de parto no muestra diferencias entre el día y la noche. No hemos encontrado diferencias en la incidencia de complicaciones en la punción ni de analgesia incompleta, deficiente o necesidad de re-punción. Conclusiones: Parece que el cansancio o la falta de sue o no influyen en la incidencia de complicaciones en la analgesia para el trabajo de parto en una unidad de atención las 24 horas. Probablemente, los médicos se ven incentivados por la realización de una tarea interesante. Introduction: Sleep deprivation effects in vigilance, performance and complications have been previously studied in general population and in medical tasks too. Results from these studies weren’t definitive. Aim: Our objective is to compare the number of complications during the epidural puncture itself, (haematic, paresthesias, accidental dural puncture and others) during the analgesia period (lateral, incomplete or imperfect analgesia, inefficacious, repuncture tax) and 24 hours after delivery, looking for late complications and to evaluate differences between day and night. We defined day from 9:00 to 21:59 h and night between 22:00 and 8:59h. Patients and methods: We performed a computered data-base analysis on regional blocks for labour analgesia in a level 4 universitary hospital with a 24 hours epidural analgesia unit during 2 months. Results: We have studied 1097 patients that resulted homogeneous in demographic and obstetric variables when we compared day versus night. The number of patients demanding analgesia didn’t show di
Identificación de un vehículo aéreo no tripulado
Boris Luis Martínez-Jiménez,Luis Mariano Pineda Bombino,Diamir De-Avila Rodríguez
Ingenier?-a Electr?3nica, Autom??tica y Comunicaciones , 2012, DOI: 10.1234/rielac.v33i1.101
Abstract: El desarrollo de los vehículos aéreos ha influido considerablemente en la vida del hombre. Una tendencia actual es la investigación y desarrollo de vehículos aéreos no tripulados (Unmanned Aerial Vehicles, UAV), pues estos brindan grandes ventajas en disímiles tareas como el acceso a lugares remotos, reconocimiento, supervisión y vigilancia. Durante la confección de un autopiloto para estos vehículos, la obtención del modelo matemático es una tarea primordial, pues se requiere representar fielmente la dinámica del UAV para realizar un control eficiente sobre el mismo. Aunque se realizan muchos trabajos relacionados con el modelado analítico de los aviones no tripulados, la identificación del modelo a partir de datos es un método muy utilizado debido a que es muy difícil tener en consideración todas las interacciones y fenómenos físicos presentes en estos sistemas. En este trabajo se presenta diferentes modelos dinámicos de un avión autónomo de peque o porte obtenidos aplicando varias técnicas de modelado e identificación de sistemas. En específico, se obtienen cuatro modelos con diferentes características: un modelo analítico, un modelo obtenido mediante una técnica de identificación clásica, un modelo nuero-borroso y un modelo borroso evolutivo. Finalmente, se expresan los resultados de los distintos modelos así como consideraciones sobre las utilidades de los mismos.
Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma
Carmen Martínez, José A Molina, Hortensia Alonso-Navarro, Félix J Jiménez-Jiménez, José AG Agúndez, Elena García-Martín
BMC Neurology , 2010, DOI: 10.1186/1471-2377-10-71
Abstract: Seventy one consecutive patients with brain tumors (43 with astrocytoma grade II/III and 28 with meningioma) with ages ranging 21 to 76 years, and 220 healthy controls subjects were analyzed for the frequency of the nonsynonymous PON1 genotypes L55M rs854560 and Q192R rs662. All participants were adult Caucasian individuals recruited in the central area of Spain.The frequencies of the PON1 genotypes and allelic variants of the polymorphisms PON1 L55M and PON1 Q192R did not differ significantly between patients with astrocytoma and meningioma and controls. The minor allele frequencies were as follows: PON1 55L, 0.398, 0.328 and 0.286 for patients with astrocytoma, meningioma and control individuals, respectively; PON1 192R, 0.341, 0.362 and 0.302 for patients with astrocytoma, meningioma and control individuals, respectively. Correction for age, gender, or education, made no difference in odds ratios and the p values remained non-significant. Haplotype association analyses did not identify any significant association with the risk of developing astrocytoma or meningioma.Common nonsynonymous PON1 polymorphisms are not related with the risk of developing astrocytoma and meningioma.Primary cancers of the brain and nervous system globally account for nearly 200,000 new cases per year, the highest rates being observed in developed areas [1]. The two most common histologic types of brain tumors in adults are gliomas and meningiomas, and data suggest that gliomas are more common in men, while meningiomas occur more often in women [2].The etiology of brain tumors is still poorly understood. Despite some studies suggested a possible relationship between the risk for brain tumors and several occupational and environmental exposures, including farming [3-5] and pesticides and/or herbicides [2,5-10], others failed to show this association [11-13]. A recent multicenter case-control study examining incident glioma and meningioma risk associated with occupational exposure to insect
Hemoptisis amenazante y estenosis de venas pulmonares tras ablación por fibrilación auricular Threatening hemoptysis and pulmonary vein stenosis after ablation due to atrial fibrillation
M. Aguilar-Cabello,R. Martín-Bermúdez,J. Jiménez-Jiménez,J.J. Egea-Guerrero
Medicina Intensiva , 2012,
Abstract:
Identificación de un vehículo aéreo no tripulado
Martínez-Jiménez,Boris L.; Pineda-Bombino,Luis M.; Martínez-Carmenate,Miguel E.; De-ávila-Rodríguez,Diamir; Hernández-Santana,Luis;
Ingenier?-a Electr?3nica, Autom??tica y Comunicaciones , 2012,
Abstract: the aerial vehicles development has significantly influenced in human life. the research and development of unmanned aerial vehicles (uavs) is a current trend, due to they offer great advantages in dissimilar tasks such as remote access, reconnaissance, surveillance and monitoring. during autopilot construction for these vehicles, to obtain a mathematical model is a primary task, because it is required to accurately represent the uav's dynamics to perform an efficient control over it. although many works related to analytical modeling of unmanned aircraft are doing, model identification from data is a widely used method because it is very difficult to take into account all interactions and physical phenomena present in these systems. in this paper, dynamic models of a small-sized autonomous plane obtained by applying various techniques of modeling and system identification are presented. specifically, four models with different features are obtained: an analytical model, a model obtained by classical identification technique, a nuero-fuzzy model and an evolving fuzzy model. finally, comparison results among obtained models are expressed as well as profit considerations about them.
Target Prediction for an Open Access Set of Compounds Active against Mycobacterium tuberculosis
Francisco Martínez-Jiménez,George Papadatos,Lun Yang,Iain M. Wallace,Vinod Kumar,Ursula Pieper,Andrej Sali,James R. Brown ,John P. Overington ,Marc A. Marti-Renom
PLOS Computational Biology , 2013, DOI: 10.1371/journal.pcbi.1003253
Abstract: Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects an estimated two billion people worldwide and is the leading cause of mortality due to infectious disease. The development of new anti-TB therapeutics is required, because of the emergence of multi-drug resistance strains as well as co-infection with other pathogens, especially HIV. Recently, the pharmaceutical company GlaxoSmithKline published the results of a high-throughput screen (HTS) of their two million compound library for anti-mycobacterial phenotypes. The screen revealed 776 compounds with significant activity against the M. tuberculosis H37Rv strain, including a subset of 177 prioritized compounds with high potency and low in vitro cytotoxicity. The next major challenge is the identification of the target proteins. Here, we use a computational approach that integrates historical bioassay data, chemical properties and structural comparisons of selected compounds to propose their potential targets in M. tuberculosis. We predicted 139 target - compound links, providing a necessary basis for further studies to characterize the mode of action of these compounds. The results from our analysis, including the predicted structural models, are available to the wider scientific community in the open source mode, to encourage further development of novel TB therapeutics.
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