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Search Results: 1 - 10 of 28154 matches for " Sanjeev Kumar Sharma "
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Nanoparticle Paclitaxel (Nanoxel) as a Safe and Cost-Effective Radio-Sensitizer in Locally Advanced Head and Neck Carcinoma  [PDF]
Akshay Nigam, Anupama Sharma, Sanjeev Kumar Singh
Journal of Cancer Therapy (JCT) , 2012, DOI: 10.4236/jct.2012.31006
Abstract: Squamous cell carcinoma of the head and neck (SCCHN) is a common malignancy. It is the 7th most common malignancy. Approximately 45,000 new cases are diagnosed each year in the USA. In present study 10 patients were selected of age group between 40 - 60 years from Gwalior-Chambal region, among them 3 were females and 7 were males. 3 patients were suffering from tonsilitis, 4 from Laryngeal carcinoma, 2 from carcinoma in maxillary antrum and 1 patient was suffering from carcinoma of whole tongue. The aim of present study is to evaluate the safety of nanoparticle paclitaxel (Nanoxel, a plant alkaloid) in combination with radiation in the treatment of locally advanced head and neck carcinoma. Further the patients were divided in 2 groups. The 1st group received nanoxel (plant alkaloid) administered concomitantly with radiation therapy. 2nd group received gemcitabine administered in combination with radiation therapy. 9 patients showed response for the therapy. The adverse effects in arm A, 2 patients showed anemia less than 8 gm of Hemoglobin, 2 patient showed leucopenia and 1 patient showed diarrhoea, Nausea/vomiting were shown by 4 patients, in arm B, 1 patient showed leucopenia, 1 patient showed anemia less than 9 gm hemoglobin and 5 patient showed sensory neuropathy. Nanoxel (plant alkaloid) showed best results in the case of head and neck carcinoma. The dose of 30 mg/kg b.w showed best safety with best clinical effect in term of less time of patient admission (hardly 30 mins) with less side effects with greater clinical effects in our study.
Error Probability of Different Modulation Schemes for OFDM based WLAN standard IEEE 802.11a
sanjeev kumar,Swati Sharma
International Journal of Engineering , 2010,
Abstract: Orthogonal Frequency Division Multiplexing (OFDM) is a key technique for achieving high data rates and spectral efficiency requirements for wireless communication systems. This paper presents a modeling and simulation of OFDM based on WLAN standard (IEEE 802.11a). Performance of OFDM is evaluated for different modulation schemes such as PSK, QAM, DQPSK, and OQPSK. The performance of OFDM is compared in terms of BER vs SNR for different modulation formats.
BER Performance Evaluation of FFT-OFDM and DWT-OFDM
Swati Sharma,Sanjeev Kumar
International Journal of Network and Mobile Technologies , 2011,
Abstract: Orthogonal frequency division multiplexing (OFDM) is a special form of multi carrier transmission which has found its application in a number of wireless and wireline systems. In an OFDM scheme, a large number of orthogonal, overlapping, narrow band sub-channels or subcarriers, transmitted in parallel, divide the availabletransmission bandwidth. The separation of the subcarriers is theoretically minimal such that there is a very compact spectral utilization. This paper presents the overview and then the performance evaluation results of an OFDM system by using Fast Fourier Transform (FFT) and Discrete Wavelet Transform (DWT). The results presented in the paper are based on computer simulations performed using Matlab; a highly efficient tool for different applications.
Implementation Ofwed Basedremote Grid Monitoring
Rishikesh Kumar,Sanjeev Kumar Sharma,Ravindra Kumar
International Journal of Electronics and Computer Science Engineering , 2012,
Abstract: Wireless Grid control is a monitoring & controlling system is used to collect and transfer the data from power generating stations to remote control unit. In this work, a method using Ethernet & AVR-ATMEGA Microcontroller based control unit. This is based on remote data transfer through Ethernet on internet. The system is compatible to access, monitoring of equipment parameters through the network and web browser in real time.
Vipin Kumar* , Sanjeev Sharma and Pankaj Kumar Modi
International Journal of Pharmaceutical Sciences and Research , 2013,
Abstract: Introduction: Solanum nigrum (S. nigrum) has been shown to be hepatoprotective by Ayurvedic physicians but has not been scientifically evaluated so far. So, the present study was undertaken to explore the hepatoprotective activity of S. nigrum against experimentally induced hepatotoxicity in albino rats.Aim of the study: To explore the hepatoprotective activity of S. nigrum.Materials and Methods: Albino Wistar rats weighing 150-200g of either sex were divided into six groups of six animals each. Group I was given normal saline (PO), group II Carbon tetrachloride (CCl4) (IP), group III Liv. 52 syrup for twenty days followed by carbon tetrachloride, group IV, V & VI received aqueous extract of Solanum nigrum ( 2ml/100g/day twice daily) orally for 10, 20 & 30 days respectively followed by CCl4. Blood was collected from anaesthetized animals & liver was dissected out. Alanine transaminase (ALT), alkaline phosphatase (ALP) & Total bilirubin were estimated and liver was subjected to histopathological examination.Results: ALT, ALP & Total bilirubin levels were significantly increased in CCl4 treated group but S. nigrum displayed significant limitation of rise in these parameters in group IV, V & VI. This hepatoprotection was also reflected in histologal changes. Conclusion: It can be concluded from the present study that S. nigrum extract is a potent hepatoprotective agent. It is assumed that this hepatoprotective effect of S. nigrum may be due to several reasons such as antioxidant, free radical scavenger and hepatic regeneration.
Survey of propagation Model in wireless Network
Hemant Kumar Sharma,Sanjeev Sharma,Krishna Kumar Pandey
International Journal of Computer Science Issues , 2011,
Abstract: To implementation of mobile ad hoc network wave propagation models are necessary to determine propagation characteristic through a medium. Wireless mobile ad hoc networks are self creating and self organizing entity. Propagation study provides an estimation of signal characteristics. Accurate prediction of radio propagation behaviour for MANET is becoming a difficult task. This paper presents investigation of propagation model. Radio wave propagation mechanisms are absorption, reflection, refraction, diffraction and scattering. This paper discuss free space model, two rays model, and cost 231 hata and its variants and fading model, and summarized the advantages and disadvantages of these model. This study would be helpful in choosing the correct propagation model.
Hepatitis B Virus: Inactive carriers
Sanjeev Kumar Sharma, Nitin Saini, Yogesh Chwla
Virology Journal , 2005, DOI: 10.1186/1743-422x-2-82
Abstract: Hepatitis B virus (HBV) infection and its sequelae are major global health problems [1]. It is estimated that 400 million people worldwide are HBV carriers [2]. The natural history of hepatitis B is complex and is influenced by many factors, including age at infection, viral factors (HBV genotype, viral mutations, level of HBV replication), host factors (gender, age, and immune status), and exogenous factors such as concurrent infection with other hepatotropic viruses or alcohol. The clinical spectrum of HBV infection ranges from subclinical to acute symptomatic hepatitis or, rarely, fulminant hepatitis during the acute phase and from the inactive hepatitis B surface antigen (HBsAg) carrier state to chronic hepatitis, cirrhosis, and its complications during the chronic phase [3,4]. Approximately 15 to 40% of people who develop chronic HBV infection are expected to progress to cirrhosis and end-stage liver disease [1]. Difficulties in defining the natural history of chronic hepatitis B include the indolent course of the disease, the lack of symptoms during the early stages, and the heterogeneity of the disease. Understanding the natural history and prognosis of hepatitis B is the basis for disease management and for designing better therapeutic strategies.HBV belongs to the family hepdnaviruses. The HBV genome is a relaxed circular, partially double stranded DNA of approximately 3,200 base pairs. There are four partially overlapping open reading frames encoding the envelope (pre-S/S), core (precore/core), polymerase, and X proteins [5]. The pre-S/S open reading frame encodes the large, middle, and small surface glycoproteins. The precore/core open reading frame is translated into precore polypeptide which is modified in to a soluble protein, the hepatitis B e antigen (HBeAg), and the nucleocapsid core protein hepatitis B core antigen (HBc Ag) [5]. The polymerase protein functions as reverse transcriptase as well as DNA polymerase. The X protein is a potent transactiv
To Investigate the Effect of Pressure on the DC Resistance of the Aloe-vera (Aloe Barbadensis Miller) Leaves
Sanjeev Kumar Sharma,Randhir Singh,Parveen Lehana
International Journal of Engineering and Advanced Technology , 2012,
Abstract: In nature, plants interact with many environmental factors such as winds, monsoon rains, touch, and herbivore attacks, in addition to many other ruthless mechanical perturbations that can menace plant survival. As a result, over many years of evolution, plants have developed very sensitive mechanisms through which they can identify and respond to even slight stimuli such as touch. Some plants respond behaviorally to the touch stimulus within seconds, while others show morphogenetic alterations over long periods of time, ranging from days to weeks. Aloe-vera plant has been known and used for centuries for its health, beauty, medicinal, and skin care properties. The name Aloe Vera derives from the Arabic word “Alloeh” meaning “ shining bitter substance,” while “vera” in Latin means “true”. In this paper, investigations were carried out to study the effect of DC resistance of the Aloe-vera leaves. The resistance of the leaf measured shows a comparative change with the change in the apply pressure on the leaf. The resistance of the leaf tissue decreases with the corresponding increased in applies pressure between the electrodes due to increase in current path. A mechano-stimulus received at the cell wall may cause alterations in the intracellular pressure. This pressure stimulus may lead to the translocation of sub-cellular organelles, thus transducing the stimulus to a cellular alteration with the potential for downstream effects.
Modeling and Simulation of Heat Exchanger Used in Soda Recovery
Chhaya Sharma,Sanjeev Gupta,Vipin Kumar
Lecture Notes in Engineering and Computer Science , 2011,
Psoriasis with ichthyosis vulgaris
Handa Sanjeev,Sharma Rajeev,Kumar Bhushan
Indian Journal of Dermatology, Venereology and Leprology , 1990,
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