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Search Results: 1 - 10 of 22509 matches for " Sang Cheol Kim "
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Empetrum nigrum var. japonicum Extract Suppresses Ultraviolet B-Induced Cell Damage via Absorption of Radiation and Inhibition of Oxidative Stress
Ki Cheon Kim,Daeshin Kim,Sang Cheol Kim,Eunsun Jung
Evidence-Based Complementary and Alternative Medicine , 2013, DOI: 10.1155/2013/983609
Abstract:
Nutrient Release during Residue Decomposition of Weeds Mown at Different Times in a Persimmon Orchard  [PDF]
Seong-Tae Choi, Seong-Cheol Kim, Gwang-Hwan Ahn, Doo-Sang Park, Eun-Seok Kim
Journal of Agricultural Chemistry and Environment (JACEN) , 2017, DOI: 10.4236/jacen.2017.64010
Abstract: Decomposition and nutrient release of the residue subsequent to mowing weeds remain poorly understood in persimmon orchards of South Korea. The litterbags including various weed residues were deposited on the soil surface under the tree canopy to simulate the fate of weeds mowed on 13 May, 13 July, and 13 September 2011 and 2012. Rate of decomposition and nutrient release of the residues depended on different mowing times. Residual dry mass (DM) of the 13 May weeds decreased by 17% - 21% of initial DM during 1 month and by 63% -71% until 2 months after litterbag deposition, and they?released 51% - 67% of nitrogen (N), 54% - 55% of phosphorus (P), and 92% - 94% of potassium (K) of respective initial amount until the first 2 months. The 13?July weeds rapidly decomposed during the first month, accounting for 51% - 64% of DM and released 49% - 67% of N, 27% - 54% of P, and 76% - 77% of K. When mowed on 13 September, the weed residue decomposed slower and?longer than the 13 May and 13 July weeds,
Incidence and Clinical Characteristics of Deep Vein Thrombosis (DVT) after Total Knee Arthroplasty (TKA) with DVT Chemoprophylaxis  [PDF]
Yong Sung Won, Mihyeong Kim, Kang Woong Jun, Woo Seok Nam, Sanghyun Ahn, Jeong-Kye Hwang, Sang-Dong Kim, Sun-Cheol Park, Sang Seob Yun, Won-Chul Lee, Jang-Sang Park, Jang Yong Kim
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.411064
Abstract: Objective: Deep vein thrombosis (DVT) after total knee arthroplasty (TKA) is very common and leading cause of death due to this procedure. The objective of this study was to investigate the incidence and clinical characteristics of DVT after TKA with DVT chemoprophylaxis. Methods: This is a prospective cohort study in single institution. The patients received postoperative DVT chemoprophylaxis (low molecular weight heparin (LMWH) or Fondaparinux), followed by duplex ultrasonography to check for DVT 1 - 2 weeks after TKA. The clinical characteristics were summarized and analysed by chi-square test and regression analysis. Results: Five hundred and thirty four patients were enrolled from January 2007 to December 2010. DVT chemoprophylaxis was administered in 524 (98.1%) of the 534 patients. DVT occurred in 9 subjects (1.69%); 8 subjects had DVT in the leg, and 1 subject had a pulmonary embolism. Among them, asymptomatic DVT was observed in 5 patients (0.94%). Univariate analysis showed that surgical methods (revision, P = 0.0007), body mass index (BMI) (>25, P = 0.0028), low platelet count (less than 150 × 103, P = 0.0219), time in the intensive care unit (ICU) (P < 0.0001), no administration of prophylactic LMWH (P = 0.0392), and a history of DVT (P < 0.0001) were significant risk factors of DVT. Conclusions: The incidence of DVT was 1.69% after TKA with prophylactic antithrombotic therapy. Revision surgery, BMI, low platelet count, time in ICU, absence of prophylactic LMWH and history of DVT were significant risk factors of DVT.
The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death
Hyun A Kim, Ki Byoung Lee, Sang-cheol Bae
Arthritis Research & Therapy , 2005, DOI: 10.1186/ar1705
Abstract: Articular cartilage consists of chondrocytes, the only cell type present, which are responsible for repairing tissue damage. Chondrocyte death and the pertinent signaling pathway involved have therefore been the focus of interest recently as pathogenetic factors leading to joint cartilage degradation in various forms of arthritides [1,2]. Several stimuli involved in the pathophysiology of arthritis, including nitric oxide (NO), Fas receptor ligation, and ceramide, have been reported to induce chondrocyte death in vitro [3-5].The pathogenetic involvement of NO in arthritis was first demonstrated when levels of nitrite, a stable end product of NO metabolism, were shown to be elevated in serum and synovial fluid samples of rheumatoid arthritis patients and osteoarthritis patients [6]. Moreover, because osteoarthritic cartilage produces large amounts of NO, it could serve as a powerful initiator of chondrocyte death. In addition to the negative effects of NO on cartilage matrix synthesis (i.e. the inhibition of cartilage matrix macromolecule neosynthesis), the enhancement of matrix metalloproteinase activity, and the reduction of IL-1 receptor antagonist synthesis, NO may be an important mediator of cartilage degradation. However, the precise role of NO in the induction of chondrocyte death is debatable. For example, treatment with NO donors consistently induces cell death in cultured chondrocytes [3,7], whereas the production of high levels of endogenous NO by the overexpression of inducible NO synthase in transfected chondrocytes was not found to cause cell death [8]. This discrepancy may be attributed to the use of chemical NO donors, which not only generate reactive nitrogen species but also produce various secondary reactions depending on the cellular milieu in vitro. A recent study that employed diazeniumdiolates, which have been shown to be reliable sources of NO, demonstrated that exogenous NO is not cytotoxic to cultured chondrocytes per se, and that NO can eve
A New Phenolic Amide from the Roots of Paris verticillata
Kyu Ha Lee,Min Cheol Yang,Ki Hyun Kim,Hak Cheol Kwon,Sang Un Choi,Kang Ro Lee
Molecules , 2008, DOI: 10.3390/molecules13010041
Abstract: A new phenolic amide 8, together with the nine known phenolic compounds 1-7,9 and 10 were isolated from the MeOH extract of the roots of Paris verticillata. Thestructure of the new compound 8 was determined to be 1-N-feruloylaminobutyl-4-ρ-hydroxybenzamide by spectroscopic methods. The isolated compounds were tested forcytotoxicity against four human tumor cell lines using the SRB assay.
A Study on Water Repellent Effectiveness of Natural Oil-Applied Soil as a Building Material  [PDF]
Jong-Kook Lee, Jee-Eun Lee, Seong-Cheol Park, Hee-Dong Cho, Hye-Woong Yoo, Young-Sang Kim, Seong-Ryong Ryu, Woo-Suk Kim, Dong-Joon Ahn
Open Journal of Civil Engineering (OJCE) , 2015, DOI: 10.4236/ojce.2015.51014
Abstract: This study was performed to investigate the water repellent effectiveness of natural oil-applied soil when it is used as a building material. Natural oil types such as olive oil, bean oil, perilla oil and linseed oil, which are being used for producing water repellent timber, are selected for the experiments. It is expected that perilla oil and in seed oil, which are drying oil types will have better water repellent effectiveness than the other types. For the evaluation of water repellence of natural oil-applied soil, a contact angle test was performed. A contact angle of water drop on various surface conditions were tested, and large differences were seen between the natural oil-applied soil and untreated soil. As a result, it is showed that all natural oil types have water repellent effectiveness. However, linseed oil, which is a drying oil type, shows an outstanding water repellent effectiveness value, while perila oil, which is also a drying oil type, shows the lowest value. Additionally, results show that there is no link between water repellent effectiveness and the number of applications of natural oil. Nevertheless, existing commercial water repellents show better performance than natural oil, and it is anticipated that the results of this study will provide essential information for further research to enhance the water repellent effectiveness of soil as a building material.
Genetic and Metabolic Characterization of Insomnia
Hyo-Jeong Ban,Sang Cheol Kim,Jungmin Seo,Ho-Bum Kang,Jung Kyoon Choi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0018455
Abstract: Insomnia is reported to chronically affect 10~15% of the adult population. However, very little is known about the genetics and metabolism of insomnia. Here we surveyed 10,038 Korean subjects whose genotypes have been previously profiled on a genome-wide scale. About 16.5% reported insomnia and displayed distinct metabolic changes reflecting an increase in insulin secretion, a higher risk of diabetes, and disrupted calcium signaling. Insomnia-associated genotypic differences were highly concentrated within genes involved in neural function. The most significant SNPs resided in ROR1 and PLCB1, genes known to be involved in bipolar disorder and schizophrenia, respectively. Putative enhancers, as indicated by the histone mark H3K4me1, were discovered within both genes near the significant SNPs. In neuronal cells, the enhancers were bound by PAX6, a neural transcription factor that is essential for central nervous system development. Open chromatin signatures were found on the enhancers in human pancreas, a tissue where PAX6 is known to play a role in insulin secretion. In PLCB1, CTCF was found to bind downstream of the enhancer and interact with PAX6, suggesting that it can probably inhibit gene activation by PAX6. PLCB4, a circadian gene that is closely located downstream of PLCB1, was identified as a candidate target gene. Hence, dysregulation of ROR1, PLCB1, or PLCB4 by PAX6 and CTCF may be one mechanism that links neural and pancreatic dysfunction not only in insomnia but also in the relevant psychiatric disorders that are accompanied with circadian rhythm disruption and metabolic syndrome.
Crystallographic plane-orientation dependent atomic force microscopy-based local oxidation of silicon carbide
Ahn Jung-Joon,Jo Yeong-Deuk,Kim Sang-Cheol,Lee Ji-Hoon
Nanoscale Research Letters , 2011,
Abstract: The effect of crystalline plane orientations of Silicon carbide (SiC) (a-, m-, and c-planes) on the local oxidation on 4H-SiC using atomic force microscopy (AFM) was investigated. It has been found that the AFM-based local oxidation (AFM-LO) rate on SiC is closely correlated to the atomic planar density values of different crystalline planes (a-plane, 7.45 cm-2; c-plane, 12.17 cm-2; and m-plane, 6.44 cm-2). Specifically, at room temperature and under about 40% humidity with a scan speed of 0.5 μm/s, the height of oxides on a- and m-planes 4H-SiC is 6.5 and 13 nm, respectively, whereas the height of oxides on the c-plane increased up to 30 nm. In addition, the results of AFM-LO with thermally grown oxides on the different plane orientations in SiC are compared.
Controller Design and Experiment for Tracking Mount of Movable SLR, ARGO-M
Cheol Hoon Park,Young Su Son,Sang Yong Ham,Byung In Kim
Journal of Systemics, Cybernetics and Informatics , 2012,
Abstract: Controller design procedure for prototype tracking mount of Movable SLR (Satellite Laser Ranging), ARGO-M is presented. Tracking mount of ARGO-M is altitude-azimuth type and it has two axes of elevation and azimuth to control its position. Controller consists of velocity and acceleration feed-forward controller, position controller at outer loop, velocity controller at inner loop. There are two kinds of position control modes. One is the pointing mode to move from one position to the other position as fast as possible and the other one is tracking mode to follow SLR trajectory as precise as possible. Because the requirement of tracking accuracy is less than 5 arcsec and it is very tight error budget, a sophisticated controller needs to be prepared to meet the accuracy. Especially, ARGO-M is using the cross-roller bearing at each axis to increase the mechanical accuracy, which requires add-on controller DOB (Disturbance observer) to suppress friction load and low frequency disturbances. The pointing and tracking performance of the designed controller is simulated and visualized using MATLAB/ Simulink and SimMechanics and the experimental results using test are presented as well.
Lagrangian Floer potential of orbifold spheres
Cheol-Hyun Cho,Hansol Hong,Sang-hyun Kim,Siu-Cheong Lau
Mathematics , 2014,
Abstract: For each sphere with three orbifold points, we construct an algorithm to compute the open Gromov-Witten potential, which serves as the quantum-corrected Landau-Ginzburg mirror and is an infinite series in general. This gives the first class of general-type geometries whose full potentials can be computed. As a consequence we obtain an enumerative meaning of mirror maps for elliptic curve quotients. Furthermore, we prove that the open Gromov-Witten potential is convergent, even in the general-type cases, and has an isolated singularity at the origin, which is an important ingredient of proving homological mirror symmetry.
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