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Search Results: 1 - 10 of 217255 matches for " Sandra L. Hanson "
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Trends in U.S. Voting Attitudes with a Consideration of Variation by Gender and Race/Ethnicity  [PDF]
Sandra L. Hanson
Open Journal of Political Science (OJPS) , 2016, DOI: 10.4236/ojps.2016.64038
Abstract: Low turnout rates and discussions of disaffected voters are receiving considerable attention as we approach the 2016 U.S. presidential elections. Do trends in American’s attitudes about voting and correlates of these attitudes (political involvement, efficacy, and social connectedness) confirm the pessimistic assessments and do voters across gender and race/ethnic groups think similarly? Data from the American National Election Studies (ANES) provide some reason for optimism. Trends over the past few presidential election periods show a majority of Americans intend to vote and this majority is increasing. Trends show increases or stability on numerous correlates of voting attitudes including political involvement and social connectedness. Trends in voting attitudes by gender and race/ethnicity show considerable variation. Women and race/ethnic minorities (especially African Americans) are an important element of the positive trends shown here. Findings on external efficacy are an exception to the generally optimistic trends with data showing a majority of respondents don’t believe public officials care what people like the respondent think. However, trends do not show an increase in negative attitudes about public officials. Implications of the findings are considered.
The Human Lung Adenocarcinoma Cell Line EKVX Produces an Infectious Xenotropic Murine Leukemia Virus
Joan L. Cmarik,Jami A. Troxler,Charlotte A. Hanson,Xiang Zhang,Sandra K. Ruscetti
Viruses , 2011, DOI: 10.3390/v3122442
Abstract: The cell lines of the NCI-60 panel represent different cancer types and have been widely utilized for drug screening and molecular target identification. Screening these cell lines for envelope proteins or gene sequences related to xenotropic murine leukemia viruses (X-MLVs) revealed that one cell line, EKVX, was a candidate for production of an infectious gammaretrovirus. The presence of a retrovirus infectious to human cells was confirmed by the cell-free transmission of infection to the human prostate cancer cell line LNCaP. Amplification and sequencing of additional proviral sequences from EKVX confirmed a high degree of similarity to X-MLV. The cell line EKVX was established following passage of the original tumor cells through nude mice, providing a possible source of the X-MLV found in the EKVX cells.
Early Children’s Literature and Aging  [PDF]
Sandra L. McGuire
Creative Education (CE) , 2016, DOI: 10.4236/ce.2016.717245
Abstract: Increased longevity is a worldwide phenomenon placing emphasis on the need for preparation for life’s later years and for maximizing the potentials of these years. Today’s children will be the older adults of tomorrow. A resource that can help to educate them about aging and prepare them for the long life ahead is early children’s literature (Preschool-Primary). This literature can provide children with a holistic view of aging, teach them about aging and the aging process, promote positive attitudes about aging, and promote positive aging. Selecting early children’s literature for aging content, resources for finding early children’s literature to promote positive aging, and examples of early children’s literature to promote positive aging are presented.
Aging Education: A Worldwide Imperative  [PDF]
Sandra L. McGuire
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.812128
Abstract: Life expectancy is increasing worldwide. Unfortunately, people are generally not prepared for this long life ahead and have ageist attitudes that inhibit maximizing the “longevity dividend” they have been given. Aging education can prepare people for life’s later years and combat ageism. It can reimage aging as a time of continued growth, development?and?fulfillment. Unfortunately, aging education is not a common occurrence. This education needs to begin with children and continue throughout life. This article discusses why we need to teach about aging?and?aging education content, suggests a conceptual framework for aging education, and presents aging education resources. The concept of ageism is discussed and suggestions for combating ageism are proposed.
Learning about Vegetarian Diets in School: Curricular Representations of Food and Nutrients in Elementary Health Education  [PDF]
Clara Hanson
Advances in Applied Sociology (AASoci) , 2012, DOI: 10.4236/aasoci.2012.21010
Abstract: This paper examines the way non-meat and plant based diets are discussed in four elementary curricula. The author used an open coding technique of grounded theory to understand the way food, nutrition and vegetarianism was discussed. The curricula relied heavily upon the USDA Food Pyramid and a related concept of “balance” for nutritional information. The curricula also discussed nutrition in terms of food and food groups, rather than in terms of nutrients. Although some of the curricula included information about the benefits of vegetarian diets, the high level of use of the Food Pyramid often overwhelmed the low level of information about vegetarianism.
Female Presence and Estrous State Influence Mouse Ultrasonic Courtship Vocalizations
Jessica L. Hanson, Laura M. Hurley
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040782
Abstract: The laboratory mouse is an emerging model for context-dependent vocal signaling and reception. Mouse ultrasonic vocalizations are robustly produced in social contexts. In adults, male vocalization during courtship has become a model of interest for signal-receiver interactions. These vocalizations can be grouped into syllable types that are consistently produced by different subspecies and strains of mice. Vocalizations are unique to individuals, vary across development, and depend on social housing conditions. The behavioral significance of different syllable types, including the contexts in which different vocalizations are made and the responses listeners have to different types of vocalizations, is not well understood. We examined the effect of female presence and estrous state on male vocalizations by exploring the use of syllable types and the parameters of syllables during courtship. We also explored correlations between vocalizations and other behaviors. These experimental manipulations produced four main findings: 1) vocalizations varied among males, 2) the production of USVs and an increase in the use of a specific syllable type were temporally related to mounting behavior, 3) the frequency (kHz), bandwidth, and duration of syllables produced by males were influenced by the estrous phase of female partners, and 4) syllable types changed when females were removed. These findings show that mouse ultrasonic courtship vocalizations are sensitive to changes in female phase and presence, further demonstrating the context-sensitivity of these calls.
An Alkali Activated Binder for High Chemical Resistant Self-Leveling Mortar  [PDF]
Henrik L. Funke, Sandra Gelbrich, Lothar Kroll
Open Journal of Composite Materials (OJCM) , 2016, DOI: 10.4236/ojcm.2016.64013
Abstract: This paper reports the development of an Alkali Activated Binder (AAB) with an emphasis on the performance and the durability of the AAB-matrix. For the development of the matrix, the reactive components granulated slag and coal fly ash were used, which were alkali activated with a mixture of sodium hydroxide (2 - 10 mol/l) and aqueous sodium silicate solution (SiO2/Na2O molar ratio: 2.1) at ambient temperature. A sodium hydroxide concentration of 5.5 mol/l revealed the best compromise between setting time and mechanical strengths of the AAB. With this sodium hydroxide concentration, the compressive and the 3-point bending tensile strength of the hardened AAB were 53.4 and 5.5 MPa respectively after 14 days. As a result of the investigation of the acid resistance, the AAB-matrix showed a very high acid resistance in comparison to ordinary Portland cement concrete. In addition, the AAB had a high frost resistance, which had been validated by the capillary suction, internal damage and freeze thaw test with a relative dynamic E-Modulus of 93% and a total amount of scaled material of 30 g/m2 after 28 freeze-thaw cycles (exposure class: XF3).
Function-Integrative Textile Reinforced Concrete Shells  [PDF]
Sandra Gelbrich, Henrik L. Funke, Lothar Kroll
Open Journal of Composite Materials (OJCM) , 2018, DOI: 10.4236/ojcm.2018.84013
This paper presents the development and technological implementation of textile reinforced concrete (TRC) shells with integrated functions, such as illumination and light control. In that regard the establishment of material, structural and technological foundations along the entire value chain are of central importance: From the light-weight design idea to the demonstrator and reference object, to the technological implementation for the transfer of the research results into practice. The development of the material included the requirement-oriented composition of a high-strength fine grained concrete with an integrated textile reinforcement, such as carbon knitted fabrics. Innovations in formwork solutions provide new possibilities for concrete constructions. So, a bionic optimized shape of the pavilion was developed, realized by four connected TRC-lightweight-shells. The thin-walled TRC-shells were manufactured with a formwork made of glass-fibre reinforced polymer (GFRP). An advantage of the GFRP-formwork is the freedom of design concerning the formwork shape. Moreover, an excellent concrete quality can be achieved, while the production of the precast concrete components is simple and efficient simultaneously. After the production the new TRC-shells were installed and assembled on the campus of TU-Chemnitz. A special feature of the research pavilions are the LED light strips integrated in the shell elements, providing homogeneous illumination.
3D Galactic dust extinction mapping with multi-band photometry
R. J. Hanson,C. A. L. Bailer-Jones
Physics , 2013, DOI: 10.1093/mnras/stt2401
Abstract: We present a method to simultaneously infer the interstellar extinction parameters $A_0$ and $R_0$, stellar effective temperature $T_{\rm eff}$, and distance modulus $\mu$ in a Bayesian framework. Using multi-band photometry from SDSS and UKIDSS, we train a forward model to emulate the colour-change due to physical properties of stars and the interstellar medium for temperatures from 4000 to 9000 K and extinctions from 0 to 5 mag. We introduce a Hertzsprung-Russel diagram prior to account for physical constraints on the distribution of stars in the temperature-absolute magnitude plane. This allows us to infer distances probabilistically. Influences of colour information, priors and model parameters are explored. Residual mean absolute errors (MAEs) on a set of objects for extinction and temperature are 0.2 mag and 300 K, respectively, for $R_0$ fixed to 3.1. For variable $R_0$, we obtain MAEs of 0.37 mag, 412.9 K and 0.74 for $A_0$, $T_{\rm eff}$ and $R_0$, respectively. Distance moduli are accurate to approximately 2 mag. Quantifying the precisions of individual parameter estimates with $68\%$ confidence interval of the posterior distribution, we obtain 0.05 mag, 66 K, 2 mag and 0.07 for $A_0$, $T_{\rm eff}$, $\mu$ and $R_0$, respectively, although we find that these underestimate the accuracy of the model. We produce two-dimensional maps in extinction and $R_0$ that are compared to previous work. Furthermore we incorporate the inferred distance information to compute fully probabilistic distance profiles for individual lines of sight. The individual stellar AP estimates, combined with inferred 3D information will make possible many Galactic science and modelling applications. Adapting our method to work with other surveys, such as Pan-STARRS and Gaia, will allow us to probe other regions of the Galaxy.
The ORF1 Protein Encoded by LINE-1: Structure and Function During L1 Retrotransposition
Sandra L. Martin
Journal of Biomedicine and Biotechnology , 2006, DOI: 10.1155/jbb/2006/45621
Abstract: LINE-1 or L1 is an autonomous non-LTR retrotransposon in mammals. Retrotransposition requires the function of the two L1-encoded polypeptides, ORF1p and ORF2p. Early recognition of regions of homology between the predicted amino acid sequence of ORF2 and known endonuclease and reverse transcriptase enzymes led to testable hypotheses regarding the function of ORF2p in retrotransposition. As predicted, ORF2p has been demonstrated to have both endonuclease and reverse transcriptase activities. In contrast, no homologs of known function have contributed to our understanding of the function of ORF1p during retrotransposition. Nevertheless, significant advances have been made such that we now know that ORF1p is a high-affinity RNA-binding protein that forms a ribonucleoprotein particle together with L1 RNA. Furthermore, ORF1p is a nucleic acid chaperone and this nucleic acid chaperone activity is required for L1 retrotransposition.
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