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Search Results: 1 - 10 of 772 matches for " Sahin Onder "
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Presence of interferon regulatory factor-1 in aggressive and nonaggressive histological variants of basal cell carcinoma specimens
Turhan-Haktanir Nurten,Dilek F,Demir Yavuz,Sahin Onder
Journal of Cutaneous and Aesthetic Surgery , 2010,
Abstract: Background : Expression of Interferon regulatory factor-1 (IRF-1) has been demonstrated in a variety of cancers previously. To the best of our knowledge, there is only one report about the IRF-1 expression in basal cell carcinoma (BCC) specimens, which has demonstrated increased expression of the IRF-1 gene in BCC versus normal skin. Furthermore, IRF-1 expression has not been compared between aggressive and nonaggressive subtypes of BCC before. Aims : Our aim is to examine the relation between IRF-1 staining patterns of aggressive and nonaggressive histological subtypes of BCC. Materials and Methods : Thirty-seven archival tissue specimens from 33 BCC patients were stained for cytoplasmic and nuclear IRF-1. Twenty-five tumors were grouped as nonaggressive and 12 were grouped as aggressive histological variants, according to the established criteria. Results : IRF-1 was not only expressed in tumor cells, but also in some surrounding inflammatory cells. There was no significant difference between the groups for cytoplasmic or nuclear IRF-1 staining. Aggressive or nonaggressive histological subtypes did not show any statistical difference for gender, relapse, treatment method, or localization. When staining was compared with gender, relapse, treatment method, localization, and tumor grades, no significant difference was found. Conclusions : Interferon seems to be expressed in BCCs with both aggressive and non aggressive histology. Further studies are needed to elaborate the precise diagnostic and prognostic roles and utility of interferon in the treatment of BCC.
A rare cutaneous tumor of the axilla: Apocrine adenocarcinoma
Karaca Semsettin,Kulac Mustafa,Sahin Onder,Esme Hidir
Indian Journal of Dermatology , 2007,
Abstract: Sweat gland neoplasms are rare with approximately 200 cases of eccrine sweat gland and less than 50 cases of apocrine gland carcinoma being reported in the worldwide literature. More than half of the reported cases with apocrine adenocarcinoma had lymph node metastases at the time of diagnosis. We report a case of a 56-year-old man, presented with a left axillary slow-growing seven year old painless nodule. Histopathological examination revealed an invasive apocrine adenocarcinoma with lymph node metastases. The patient successfully treated with total excision and radiotherapy. Apocrine adenocarcinoma is a rare malignancy with high metastatic potential that occurs mostly in the axilla. Physicians should be aware of this entity while differentiating cutaneous tumor located on the axillary region.
Expression of cyclooxygenase-1 and 2 in chronic tonsillitis
Dilek Fatma,Sahin Onder,Tokyol Cigdem,Mazlum Mustafa
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Objectives: Prostaglandins are critical mediators of inflammation and affect both humoral and cell-mediated immune responses. Recent findings show that T and B cells express COX-2 upon activation. The purpose of this study is to investigate the potential occurrence of COX-1 and COX-2 immunoreactivity in cases of chronic tonsillitis and to determine the sites of their expression. In addition, their expression in adult patients is compared with that in child patients. Materials and Methods: Immunohistochemical techniques were used to evaluate the expression of the enzymes COX-1 and COX-2, in chronic tonsillitis tissue specimens from adults (n = 15) and children (n = 15). Results: There was no staining in surface epithelium or reticulated crypt epithelium. COX-1 and COX-2 expressions were observed mainly in the intraepithelial lymphoid cells in reticulated crypt epithelium and subepithelial cells. Also, COX-1 and COX-2 stained cells were found in the germinal center. There was no difference of the expressions of COX-1 and COX-2 among adults and children. The only significant difference noted between the adults and children was that, the adults had rich subepithelial plasma cells. Conclusion: Activated B and T cells express COX-1 and COX-2 in paraffin-embedded tissue sections of chronic tonsillitis. Further studies need to be performed to elucidate expression of COX enzymes and their immunologic role in tonsil diseases. They will play an important role in the treatment of chronic tonsillitis. Additional studies are warranted to study the effects of NSAIDs and selective COX-2 inhibitors in chronic tonsillitis
Power System Analysis of an Aero-Engine  [PDF]
Onder Turan, Hakan Aydin
Journal of Power and Energy Engineering (JPEE) , 2015, DOI: 10.4236/jpee.2015.34060

The aim of this study is analyzed in detail for better understanding of energy and power of an aero-engine. In this regard, this study presents energy equations were applied to the turbofan engine components. The engine has a thrust range of 82 to 109 kN. It consists of fan, axial low pressure compressor (LPC), axial high pressure compressor (HPC), an annular combustion chamber, high-pressure turbine (HPT) and low pressure turbine (LPT). The results show that power of the engine flow approaches a maximum value to be 82.85 MW in the combustor outlet, while minimum power is observed at LPC inlet with the value of 1.37 MW. Furthermore, important parameters of the engine are also analyzed from reverse-engineering method. It is expected that results of this study will be beneficial of power, cogeneration and aero-propulsive generation systems in similar environment.

The Kinetic Energy Formula for the Closed Planar Homothetic Inverse Motions in Complex Plane  [PDF]
Onder Sener, Ayhan Tutar
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.35068
Abstract: In this paper, the kinetic energy formula was expressed during one-parameter closed planar homothetic inverse motions in complex plane. Then the relation between the kinetic energy formula and the Steiner formula was given. As an example the sagittal motion of a telescopic crane was considered. This motion was described by a double hinge consisting of the fixed control panel of telescopic crane and the moving arm of telescopic crane. The results were applied to experimentally measured motion.
On the Kinematics for the Closed Planar Homothetic Inverse Motions in Complex Plane  [PDF]
Onder Sener, Ayhan Tutar
Journal of Applied Mathematics and Physics (JAMP) , 2017, DOI: 10.4236/jamp.2017.55099
Abstract: In this paper, the Steiner area formula and the polar moment of inertia were expressed during one-parameter closed planar homothetic inverse motions in complex plane. The Steiner point was defined when the rotation number was different zero and it was called the Steiner normal when the rotation number was equal to zero. The fixed pole point was given with its components and its relation between Steiner point or Steiner normal was explained. The sagittal motion of a telescopic crane was considered as an example. This motion was described by a double hinge consisting of the fixed control panel of the telescopic crane and the moving arm of the telescopic crane. The theoretical concepts and results were applied for this motion.
Gender Equity in Education  [PDF]
Elmas Sahin
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.21007
Abstract: Numerous studies show that society often treats boys and girls differently. Although gender inequalities in education have changed much in recent decades thanks to the fight for womens rights, inequity between the sexes continues to flourish nowadays. This article focuses on how and why education is the key to gender equality, and the importance of gender equity in education system in order to create a better environment for girls under traditional pressures. It will also query whether a philosophy of education offering the same opportunities to young women and men, teaching the same things at the same time, in the same place, with the same methods, and under the same system is necessary or not.
Meta-Herpetic Keratitis and Therapeutic Approach: Case Report  [PDF]
Ozlem Sahin
Open Journal of Ophthalmology (OJOph) , 2014, DOI: 10.4236/ojoph.2014.43012

The purpose of this study is to disclose the steps in the therapeutic approach for meta-herpetic corneal ulcer. Report of a case with anterior segment photography was used. The 6 months of follow-up results of the case were disclosed. The efficacy of the therapeutic approach for meta-herpetic corneal ulcer was discussed.

Women Travel Writings: A Comparative Journey  [PDF]
Elmas Sahin
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.31008
Abstract: Since the 18th century, Turkey increasingly played a significant role for women travel writers such as Lady Marry Montague, Elizabeth Craven, Julia Pardoe, Hester Donaldson Jenkins, Eliza Cheney Abbott Schneider, Mary Mills Patrick, Grace Ellison, who were in curiosity to discover the other: their cultures, customs, literatures, social, political and historical backgrounds and improvements, emancipation movements, sexualities and so on. Whereas some women writers including Zeyneb Hanim, Melek Hanim, Demetre Vaka and Halide Edib Adivar penned impressions about both European and Turkey. In this study, the works named An Englishwoman in a Turkish Harem by Grace Ellison and A Turkish Woman’s European Impressions by Zeynep Hanim will be evaluated in regard to comparative literature and cultural studies. Additionally, I argue that comparative literature accepted as a most advantageous approach for literary and cultural studies can probably contribute much more than the other disciplines to cultural studies and cultural history, even feminist cultural history, comparative cultural perspectives to literature; and or cultural studies open a large umbrella for international cultures and literatures in the light of these two works focused on literary writings, experiments, representations of occidental and oriental women, and occidental and oriental perceptions.
Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy
Oya Topaloglu,Bekir Ucan,Taner Demirci,Muyesser Sayki Arslan,Guleser Saylam,Evrim Onder,Sinan Gultekin,Alper Dilli,Mustafa Sahin,Erman Cakal,Mustafa Ozbek,Tuncay Delibasi
Case Reports in Endocrinology , 2013, DOI: 10.1155/2013/805745
Abstract: A 68-year-old man had a rapidly growing, painless neck mass, thought to be nodular goiter. Ultrasonography showed a giant, heterogeneous mass occupying the middle and superior poles and protruding outside of the left thyroid lobe. The results of the thyroid function tests were normal. Thyroid scintigraphy revealed a large hypoactive nodule in the left thyroid lobe. Complete surgical removal of tumor was performed and macroscopically demonstrated a well-demarked lesion outside the thyroid gland. Microscopically, the lesion was composed of fibroblast-like spindle cells in a patternless architecture and extensive stromal hyalinization. Immunohistochemistry showed positive reaction for CD34 in spindle cells and diffuse bcl-2 staining. The pathology was confirmed as solitary fibrous tumor. In the follow-up period after surgery, thyroid scintigraphy showed normal left thyroid lobe. Solitary fibrous tumor originated from or associated with thyroid gland is extremely rare. According to our knowledge, this is the first reported solitary fibrous tumor presenting like a cold thyroid nodule. This pathology must be considered for differential diagnosis of neck masses in the thyroid region. 1. Introduction Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm of mesenchymal origin that was first described in the pleura [1]. Since then, SFT has been recognized in various sites other than the pleura, such as mediastinum, pericardium, and peritoneum [2–4]. Head and neck SFTs are exceedingly rare, and they were firstly described as a case report in 1991 [5]. They were presented as asymptomatic slow-growing massess or with local symptoms due to compression. In most cases, complete surgical resection is the only appropriate treatment [6]. Diagnosis is often difficult and not definite until morphologic or immunohistochemical evaluation. SFT arising from the thyroid gland is also uncommon. It was first described by Taccagni et al. in 1993 [7]. Up to date and to the best of our knowledge, 23 cases of SFT in the thyroid gland have been reported in the literature, approximately all of them with benign characteristics [8–10], only 2 of them with malignant clinical features like local recurrence and metastasis [11]. Here, we present the first reported SFT mimicking hypoactive thyroid nodule in thyroid scintigraphy. 2. Case Report A 68-year-old man presented with a 2-month history of a rapidly growing mass in the left neck on the thyroid gland region. He did not have any history of thyroid disease. He did not describe any symptoms like hoarseness, dyspnea, local pain, or
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