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Search Results: 1 - 10 of 31098 matches for " Safaee Naraghi Z "
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Alopecia-Areata Like Alopecia in Mycosis Fungoides, a Case Report
F. Farnaghi,Z. Safaee Naraghi,S. Mohit
Tehran University Medical Journal , 1998,
Abstract: Mycosis Fungoides (MF) is a cutaneous T-cell lymphoma (2,5). Alopecia is rarely seen in this disease, and the reported cases are in the form of follicular mucinosis (1,2,4). In this case report a patient is presented whose lesions all showed alopecia without mucinosis. Furthermore there was a patch of alopecia without any epidermal changes, which was clinicaly identical with alopecia areata, and histologically identical with MF. After six months of treatment there is regrowth of almost normal hair on all of the lesions
Demographic and pathologic findings of squamous cell carcinoma of skin and lip in pathology department of Razi Hospital
Safaee Naraghi Z,Mortazavi MR,Omid A
Tehran University Medical Journal , 2001,
Abstract: Squamous cell carcinoma, a cancer of keratinocytes origin, mostly involves sun-exposed areas of the skin. To study the pathologic and demographic features of this disease, records of 395 patients of squamous cell carcinoma of skin and lip were reviewed. Most of the patients (83%) aged 40 years or more at the time of diagnosis. Respectively, 74.4% and 75.8% of cases with skin and lower lip carcinoma were men, but in upper lip cases frequencies of both sexes were equal. The number of patients referred from western and north-western provinces were much more than those of other provinces of the country. The most frequent histologic stage was grade I (53% and 58.8% in skin and lip carcinoma, respectively), showing that most patients visit physicians early enough, and are diagnosed in early stages of the disease.
Histiocytic syndromes and a review of medical literatures
Safaei Naraghi Z
Tehran University Medical Journal , 1994,
Abstract: Histiocytic syndromes have been studied and investigated in these recent years for their cell origin, morphology, pathology, histochemical, immuno-phenotype characteristic, and their nomenclature, but the results of all these studies are confusingly, vague and not acceptable for all scientists and pathologists. Histiocytes very in the morphology, duty and their immunological behaviour. In different lesion these cells are in the form of mononuclear, foamy cell, macrophages like plasma cell and giant cell with many nuclei. When considering malignant Histiocyte cells and benign reactive histiocytes are both present in malignant histiocytic lesion, one can recognize the diagnostic problems of the pathologist. Markers for recognizing histiocytes are numerous and are increasing rapidly, in spite of that monoclonal antibody investigation, and genetic molecular method, the results as yet are not satisfactory. We have to accept that the new method are not at all sufficient and we have to look for a better method which is more sensitive to histiocyte for diagnosis of numerous histiocytic syndromes. In this paper, we discuss the difficulties on encountered in the diagnosis, and problem in defining and nomenclature of these syndromes and, some efforts are made to present the most acceptable classification for them
Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model
SE Eskandari,A Azimzadeh,M Bahar,Z Safai Naraghi
Iranian Journal of Public Health , 2012,
Abstract: Background: Cutaneous leishmaniasis caused by L. major is an important public health problem in endemic areas. The aim of this study was to explore the therapeutic effect of microwave and or infrared radiation in the treatment of lesion induced in BALB/c mice by L. major inoculation.Methods: The footpad lesion was induced in BALB/c mice by inoculation of L. major promastigotes subcutaneously. The lesion was treated with 600 watts power, 2.450 GHz frequency and/or infrared device with 150 watts and a wave length of 890 nanometres. The size of the lesion was recorded by footpad swelling measurement every 10 days. Results: The lesion growth was significantly hampered in treated mice compared with the untreated control group (P<0.05). Infrared radiation was more effective than microwave in inhibiting ulcer enlargement.Conclusion: Infrared radiation and microwave significantly hampered L. major lesion growth in BALB/c mice. This therapeutic effect was more in infrared radiation treated mice than microwave treated mice.
An epidemiologic clinical and pathological study of basal cell epithelioma (BCE) in Razi Dermatological Hospital
Akhyani M,Ghaninezhad Ahary H,Safaie Naraghi Z,Rezaie A
Tehran University Medical Journal , 1998,
Abstract: Our purpose was demographic clinical and pathological aspect of BCE in patients seen in Razi Hospital, during a six-month period (75.8.12 to 76.2.12). Results: From the total 20000 patients, 103 cases of BCE were detected. (0.5%). The male female ratio was 1.71 BCE was more frequent in sixth decade. 40.8% of patients were fair skin (Type II), 54.4% tawny (Type III) and 4.9% brown (Type IV, V). 15.5% of patients had a past history of freckles and history of radiotherapy in childhood was present in 41.7% 89.3% had no history of acne and seborrhea. The scalp was the most common site of BCE. The most common clinical type was nodular BCE and solid BCE was the dominant histological feature. Conclusion: BCE was more common in male and fair skin patients with dry skin. In those having history of radiotherapy of the scalp, lesions were seen mostly on the scalp, forehead and neck: pigmented BCE was predominant in this group.
Z. Naraghi,H. Ghaninejad,M. Akhyani,D. Akbari
Acta Medica Iranica , 2005,
Abstract: Basal cell carcinoma (BCC) is the most common cancer of the skin. Definite diagnosis usually requires histological examination but recently it has been suggested that cytological examination of skin smear can be used as an alternative. To evaluate sensitivity and specificity of cytological examination, a total of 125 skin lesions, clinically suspected to be BCC were studied. Cytological samples were taken by scraping a scalpel blade over the lesion and smearing the cells on to a glass slide. The specimens were air- dried and stained with May-Grünwald-Giemsa. An incision biopsy was performed for histopathological study. The cytological results were compared with the histopathological results of the lesions. Histopathology revealed BCC in 102 lesions (81.6%), squamous cell carcinoma (SCC) in 11 lesions (8.8%), seborrheic keratosis in 6 lesions (4.8%), actinic keratosis in 5 lesions (4%) and keratoacanthoma in 1 lesion (0.8%). Cytological examination reported BCC in 90(72%), SCC in 13 ( 10.4%) and seborrheic keratosis in 6 lesions (4.8%) and was non-diagnostic in 16 lesions (12.8%). The sensitivity and specificity of the cytology in identifying all of the BCC types were 87.3% and 95.3%, respectively. In conclusion, cytological examination is easy to perform, saves time, requires a minimum of equipments and can be considered a reliable method in the diagnosis of suspected cutaneous BCC.
Mehregan,D.R.,Naraghi,Z. Mehregan A.H.
Acta Medica Iranica , 1996,
Abstract: We are reporting on a patient with a large linear syringocystadenoma papiliferum present at birth over the anterior surface of the left leg. Histologic findings and the results of immitnohlstochcmicat staining with monoclonal antihotlies CEA and IKH-4 suggest derivation from eccrinc glands.
Z. Safaii Naraghi.,P. Mansouri M.R. Mortazavi
Acta Medica Iranica , 1996,
Abstract: Scleromyxedema is a rare, chronic, progressive, fibromucinous disorder of unknown etiology, characterized by lichenoid waxy papules and firm induration of skin of trunk, face, forearm and hands; fibroblast proliferation and mucin deposition in the upper dermis. Cutaneous involvement is characteristic but there are several associated systemic manifestations: We observed a case of scleromyxedema with multiple systemic manifestations including endocrinopathy and hypothyroidism. Scleromyxedema is a multisystem disorder associated with multiple organ involvement including liver, muscle, kidney and could be associated with endocrinopathies including hypothyroidism.
D. Akbari,Z. Naraghi,N. Emadi H. Ghaninejad
Acta Medica Iranica , 2005,
Abstract: Sebaceous carcinoma is a relatively rare cutaneous tumor that is most commonly derived from the sebaceous glands located in periorbital area. The extraocular occurrence of this tumor is very rare. We report a case of an 85 years old woman who presented with a slowly enlarging mass on the right temporal region. Histological examination of the lesion revealed a malignant sebaceous carcinoma occurring in conjunction with nevus sebaceous. The lesion was surgically excised completely.
Endonasal endoscopic Laser-assisted Dacryocystorhinostomy
"Naraghi M,Tabatabaee Mohammadi SZ,Zolfkhani Z,Kashfi A "
Acta Medica Iranica , 2002,
Abstract: Endonasal endoscopic laser-assisted dacryocystorhinostomy has many advantages over conventional external dacryocystorhinostomy. This technique avoids a cutaneous scar and causes less surgical trauma and bleeding than that seen in conventional lacrimal surgery. A total of 20 endoscopic laser-assisted dacryocystorhinostomy in 16 patients were performed between 1998 and 1999. the procedure was successful in 90% of cases, with no major complications. This success rate is comparable with external dacryocystorhinostomy. Silicone tubing was applied in 11 cases. The difference of success rates between the two groups (with and without silicone tubing) was not significant. It seems that creading a patent rhinostomy plays a more important role to achieve desirable results. Endonasal endoscopic laser-assisted dacryocystor-hinostomy provides a simple, bloodless, and incisionless alternative to external dacryocytorhinostomy in the majority of the patients suffering from symptoms of lacrimal obstruction.
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