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Search Results: 1 - 10 of 2833 matches for " Saad Khaled "
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Relationship between Patient-Dependent Parameters and Radiation Dose Rates Measured around Patients Undergoing PET/CT Imaging Using 18F-FDG  [PDF]
Khaled Soliman, Saad Al Qahtani, Ahmed Alenezi
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2018, DOI: 10.4236/ijmpcero.2018.73033
Abstract: Objectives: Patients undergoing 18F-FDG PET/CT imaging are considered external radiation sources. Accurate dose rate estimates are important for conducting realistic risk assessments and performing dose reconstruction in cases of accidental exposures. The patient radiation self-attenuation factor is assumed to be a function of the patient’s body size metrics, but we can use these metrics to predict the dose rate around the patients with accuracy. The objective of this work was first to measure the patient attenuation factor by performing direct dose rate measurements from patients undergoing PET/CT imaging studies using 18F-FDG. The second objective was to study the possible correlation between the measured dose rate constant per unit activity from the patients and their body size metrics; five metrics were tested in this work. The last objective was to measure the patients’ voiding factor. Methods: We have measured dose rates at one meter from 57 patients and noted the patients height (H), weight (W) and calculated patient size metrics namely: Equivalent Cylindrical Diameter (ECD), Equivalent Spherical Diameter (ESD) and the Body Mass Index (BMI). Results: The measured average dose rate was 92.2 ± 14 μSv·h
Does closure of chronic pilonidal sinus still remain a matter of debate after bilateral rotation flap? (N-shaped closure technique)
Awad Mohamed,Saad Khaled
Indian Journal of Plastic Surgery , 2006,
Abstract: Background: Controversy still exists about the exact cause of pilonidal sinus either acquired or congenital, and also about what is the best surgical technique for the treatment of the disease. We successfully treated chronic pilonidal sinus with a new flap technique {N-shaped bilateral rotation flap} for closure of the defect. Materials and Methods: Thirty-two patients (30 men and two women) were treated by eccentric elliptical excision of the diseased tissues down to the postsacral fascia and closure of the defect with our flap [which is a random pattern flap], then a closed suction drain was placed at the base of the wound, with its tip being brought out in the gluteal region at least 5 cm lateral to the lower end of the suture line. Results: All our patients healed completely without recurrence during a period of average follow-up of two years. Mean hospital stay was 1.5 days (range 1-5 days). Mean time to complete healing was 11.9 days (range 6-18 days). Mean time off work was 13.7 days (range 10-21 days). Two patients had wound infection and one patient a partial breakdown. The recurrence rate was 0%. Conclusions: A tension-free suture via bilateral rotation flaps with a good suction at the button of the wound for drainage of blood from the bottom of the wound is the key to the success of repair without recurrence.
Weight Loss in Animals and Humans Treated with “Weighlevel”, a Combination of Four Medicinal Plants Used in Traditional Arabic and Islamic Medicine
Omar Said,Bashar Saad,Stephen Fulder,Khaled Khalil,Eli Kassis
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nen067
Abstract: Weighlevel, a mixture of extract of four plants used in traditional Arabic and Islamic medicine as well as in European herbal medicine, was prepared and assessed for its safety and efficacy in weight loss. Leaves of Alchemilla vulgaris, Olea europaea and Mentha longifolia L., as well as seeds of Cuminum cyminum, were used. Cultured human fibroblasts treated with Weighlevel did not exhibit any sign of toxicity as evidenced by lactate dehydrogenase release. These results were confirmed in experimental studies on rats where an LD50 of 15.3?g?kg?1 was observed. Significant antioxidant properties were seen at very low concentrations of Weighlevel (10?μg?ml?1) as measured by the lipid peroxidation method. Progressive and significant weight loss was observed in chickens given this mixture weekly for 4 weeks compared with controls. Furthermore, a 3-fold increase in the thermogenesis was seen in rat interscapular brown adipose tissue following exposure to different concentrations of Weighlevel extract as determined by measurement of increased oxygen consumption. In addition, a clinical study was carried out among 80 human volunteers with a body mass index (BMI) of 30.67 ± 2.14?kg?m?2. All 80 subjects were asked to continue their usual diet but to eat only three main meals daily and to take one Weighlevel tablet 30?min before each meal. Fourteen subjects were excluded for not following the protocol, and 66 subjects were all evaluated for efficacy and tolerability of Weighlevel monthly for 3 months. Weighlevel was well tolerated by all subjects, and no side effects were reported. A progressive and significant weight loss was seen in these subjects during the whole study period. Higher levels of weight loss were seen in people with BMI of 25–30?kg?m?2 (overweight) compared to people with BMI >30?kg?m?2 (obese). The BMI was reduced after 3 months from 28.5 ± 1.2 and 32.1 ± 1.8?kg?m?2 to 24.5 ± 1.4 and 27.5 ± 2.2?kg?m?2 in overweight and obese group, respectively. Results indicate safety, tolerability and efficacy of Weighlevel. 1. Introduction Overweight is a major health challenge in the Western world with serious clinical complications such as type 2 diabetes mellitus, cerebrovascular and ischemic heart diseases. Available pharmacological therapy of obesity is limited to anorexic drugs such as amfepramon and sibutramine and one malabsorptive drug, orlistat. When added to a diet, such therapy is expected to yield weight loss of 0.2–0.4?kg?week?1, but only for few weeks due to tolerance and side effects [1]. Effective management of overweight seems to be of utmost
Multi-Wideband Compact Microstrip Patch Antenna Based on Slot Matching
Elsayed Esam Mohamed Khaled;Ayman Ayd Ramadan Saad
PIER C , 2008,
Abstract: This paper presents a new design of a compact patch antenna based on the slot matching concept. Switches are integrated with the previously inserted slots into the patch antenna to enhance the performance. The newly designed antenna is a multi-wideband antenna. It is able to achieve a return loss less than -9.54 dB and VSWR≤2 in more than four frequency bands in the range from 2 to 5GHz
A simple novel technique for closure of simple and complex pilonidal sinus with either simple (tongue-shaped) or bilobed rotation flap
Awad Mohamed,Saad Khaled,Tolba Adel,Gharib Osama
Indian Journal of Plastic Surgery , 2007,
Abstract: Background: Pilonidal sinus is a common disease in young adults that carries high postoperative morbidity and patients′ discomfort; controversy still exists regarding the best surgical technique for the treatment of the disease. We successfully treat it with a rotation flap technique (simple rotation and bilobed rotation flap). Materials and Methods: Sixty-two patients were randomized to receive surgical treatment in the form of either simple rotation or bilobed rotation flap by eccentric elliptical excision of the diseased tissues down to the sacral fascia and closure of the defect with the flap, then placing a closed suction drain at the base of the wound, with its tip being brought out in the gluteal region at least 5 cm laterally to the lower end of the suture. Results: All our patients healed completely without recurrence after a mean follow-up of about one year. Mean hospital stay 1.5 days (range 1-3) Mean time to complete healing 11.9 days (range 8-14). Mean time off work was 11.5 days (range 10-21), wound infection and breakdown, three (4.8%), recurrence (0%), and time to sitting on the toilet and walking without pain was 10-15 days. Conclusions: A tension-free suture and cleft left via the rotation flap, either the bilobed flap or monolobed, is the key to success without recurrence and low patient discomfort.
What is the best choice for repair of distal penile hypospadias: The tubularized incised plate urethroplasty or anterior urethral advancement technique?
Awad Mohamed,Tolba Adel,Saad Khaled,Zaghlol Mahmoud
Indian Journal of Plastic Surgery , 2007,
Abstract: Background and Aim: Numerous ingenious methods have been introduced to repair hypospadias with variable results. We tried to evaluate the two techniques, tubularized incised plate urethroplasty (TIP) and anterior urethral advancement (AUA) for repair of distal hypospadias and choose the best method to treat the distal type of penile hypospadias with the least complications. Materials and Methods : A total of 140 boys with distal penile hypospadias were divided into two groups. Group A (68 patients) was treated with TIP and Group B (72 patients) was treated with AUA. All the patients had an average age of three years (2-19) with variable meatal sites coronal (44) sub coronal (53) and anterior penile hypospadias (43). There was no significant difference between both groups with respect to the age and meatal sites. Results: The fistula rate in Group A was 8.8% versus 1.3% in Group B. There was no urethral stricture in both procedures. Wound dehiscence did not occur in Group A versus one case in Group B (1.3%). In Group A, 26 cases (38.3%) had mild glanular torsion and five (7.3%) had moderate glanular torsion versus none in Group B postoperatively. No postoperative chordee or binding in Group A, versus four patients (5.5%) in Group B. No significant difference was observed in both groups with respect to meatal stenosis (7.3% versus 5.5% respectively). There was a significant difference between both groups with regard to the operative time in favour of Group B. Good cosmetic appearance of the glans was achieved in both techniques. Conclusion: Both techniques can treat this anomaly with a high success rate but the modified AUA technique appears to be a good choice due to its simplicity, short operative time and less fistula rate with good cosmetic results.
Maintaining a Physiological Blood Glucose Level with ‘Glucolevel’, a Combination of Four Anti-Diabetes Plants Used in the Traditional Arab Herbal Medicine
Omar Said,Stephen Fulder,Khaled Khalil,Hassan Azaizeh,Eli Kassis,Bashar Saad
Evidence-Based Complementary and Alternative Medicine , 2008, DOI: 10.1093/ecam/nem047
Abstract: Safety and anti-diabetic effects of Glucolevel, a mixture of dry extract of leaves of the Juglans regia L, Olea europea L, Urtica dioica L and Atriplex halimus L were evaluated using in vivo and in vitro test systems. No sign of toxic effects (using LDH assay) were seen in cultured human fibroblasts treated with increasing concentrations of Glucolevel. Similar observations were seen in vivo studies using rats (LD50: 25 g/kg). Anti-diabetic effects were evidenced by the augmentation of glucose uptake by yeast cells (2-folds higher) and by inhibition of glucose intestinal absorption (∼49%) in a rat gut-segment. Furthermore, treatment with Glucolevel of Streptozotocin-induced diabetic rats for 2–3 weeks showed a significant reduction in glucose levels [above 400 ± 50 mg/dl to 210 ± 22 mg/dl (P < 0.001)] and significantly improved sugar uptake during the glucose tolerance test, compared with positive control. In addition, glucose levels were tested in sixteen human volunteers, with the recent onset of type 2 diabetes mellitus, who received Glucolevel tablets 1 × 3 daily for a period of 4 weeks. Within the first week of Glucolevel consumption, baseline glucose levels were significantly reduced from 290 ± 40 to 210 ± 20 mg/dl. At baseline, a subgroup of eleven of these subjects had glucose levels below 300 mg% and the other subgroup had levels ≥ 300 mg%. Clinically acceptable glucose levels were achieved during the 2–3 weeks of therapy in the former subgroup and during the 4th week of therapy in the latter subgroup. No side effect was reported. In addition, a significant reduction in hemoglobin A1C values (8.2 ± 1.03 to 6.9 ± 0.94) was found in six patients treated with Glucolevel. Results demonstrate safety, tolerability and efficacy of herbal combinations of four plants that seem to act differently but synergistically to regulate glucose-homeostasis.
A Proximity-FED Annular Slot Antenna with Different a Band-Notch Manipulations for Ultra-Wide Band Applications
Elsayed Esam Mohamed Khaled;Ayman Ayd Ramadan Saad;Deena A. Salem
PIER B , 2012, DOI: 10.2528/PIERB11103102
Abstract: A proximity-fed annular slot antenna for UWB applications with a band rejection using different techniques is presented. The proposed antenna provides an UWB performance in the frequency range of ≈2.84 to ≈8.2 GHz with relatively stable radiation parameters. Three different techniques to construct a resonant circuit for the proposed antenna are investigated to achieve the band-notch property in the band ≈5.11 to ≈5.69 GHz band which include the WLAN and HIPERLAN/2 services without degrading the UWB performance of the antenna. Three resonators are considered; a single complementary split ring resonator (CSRR), a complementary spiral loop resonator (CSLR) and a spurline slot. Furthermore, the band-notched resonance frequency and the bandwidth can be easily controlled by adjusting the dimensions of the resonator. The proposed antenna is simulated, fabricated and measured. The measured data show very good agreements with the simulated results. The proposed antenna provides almost omnidirectional patterns, relatively flat gain and high radiation efficiency over the entire UWB frequency excluding the rejected band.
A Perspective-Based Reading of Culture in English Language Teaching: From the Conventional Perspective to the Intercultural Language Teaching Perspective  [PDF]
Khaled Jebahi
Open Journal of Modern Linguistics (OJML) , 2013, DOI: 10.4236/ojml.2013.33029

This paper reviews culture as perceived in a number of language teaching perspectives. The term “culture” and its relation with language has been a center of interest in different fields of studies. Because the term “culture” is borrowed between disciplines, it is understood differently and altered in the process by the goals and traditions of the borrowers. As such culture remains an elusive concept for the language teacher. Here, I attempt to understand how culture has been understood in different English language teaching perspectives in the last fifty years. This reading helps understand how change in the teaching approach affects how culture is dealt with in class and in teaching materials.

Molecular Modeling, Docking and ADMET of Dimethylthiohydantoin Derivatives for Prostate Cancer Treatment  [PDF]
Khaled Lotfy
Journal of Biophysical Chemistry (JBPC) , 2015, DOI: 10.4236/jbpc.2015.64010
Abstract: In silico technique was applied to screen potential of 16 compounds of 5,5-dimethylthiohydantoin derivatives as androgen antagonist. The 3D structure of the protein was obtained from PDB database. Docking analysis of the compounds was performed using hex docking. Molecular modeling analysis exhibits relatively low LUMO-HOMO energy gap of the studied molecules, indicating that it would be kinetically stable. None of the compounds violated Lipinski’s parameters, making them potentially promising agents for biological activities. The title compounds exhibited the lowest docking energy of protein-ligand complex. Finally, the results indicate that these compounds are potentially as an androgen antagonist, and expected to be effective in prostate cancer treatment.
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