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Search Results: 1 - 10 of 447 matches for " SY Mudi "
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Naphthoquinolinone Derivative with Anti- Plasmodial Activity from Vitex doniana [Sweet] Stem Bark Extracts
SY Mudi
Bayero Journal of Pure and Applied Sciences , 2011,
Abstract: In an effort to identify promising phytotherapeutical substances from plants, the bark of Vitex doniana was collected, air dried and pounded. The powder was extracted with ethanol. The crude ethanol (VD1) was macerated sequentially. Four fractions obtained namely petroleum ether (VD1-01), ethyl acetate (VD1-02), chloroform (VD1-03) and methanol (VD1-04). These fractions were assayed at various concentrations (250Dg/ml, 500Dg/ml and 1000Dg/ml) for anti-malaria activity against Plasmodium falciparum and were also screened for the presence of secondary metabolites. The ethanol extract (VD1) and methanol soluble fraction (VD1-04) exhibited the highest activity against the test organism with 68.0% and 78.0% elimination at 500Dg/ml after 72 hours respectively. The VD1-04 was subjected to activity guided column chromatography that lead to isolation of pure compound VD1-04-198 named as 3-ethyl-3,4,4a,5,6,6a,10a,11,12,12a-decahydro-1H-naphtho[2,3,-g]quinolin-2-one. This was active against the malaria parasite with 89.0% elimination at 500Dg/ml after 48 hours. The phytochemical analysis showed that the plant contain flavonoids, tannins, alkaloid, reducing sugar and steroids.
Activity of Bryophyllum pinnatum S. Kurz extracts on respiratory tract pathogenic bacteria
SY Mudi, H Ibrahim
Bayero Journal of Pure and Applied Sciences , 2008,
Abstract: Ethanol extract of Bryophyllum pinnatum (commonly known as ‘Shuka halinka’ or ‘Karan masallachi’ in Hausa) (BP1) was partitioned into n-hexane, chloroform, ethyl acetate and aqueous methanol soluble fractions and labeled BP1–01, BP1–02, BP1–03 and BP1–04 respectively. These fractions were subjected to antibacterial testing against respiratory tract pathogenic bacteria. The n-hexane soluble fraction showed activity against the selected microorganism with highest on Staphylococcus aureus (12mm), Klebsiella pneumonia (11mm) and Salmonella typhi (08mm); ethyl acetate soluble fraction showed mild activity against Escherichia coli (06mm), Staphylococcus aureus (07mm) and Salmonella typhi (07mm), at 10mg/ml. The n-hexane soluble fraction was subjected to activity guided column chromatography. This leads to isolation of three bioactive compounds: BP1-01-01, BP1-01-33 and BP1-01-65. The activity of this plant’s extracts against the test bacteria coupled with the various phytochemical compounds present in the fractions is a pointer to the plant’s potential as a source of drugs that can be used against respiratory tract pathogens.
Anti-plasmodia activity of leaf extracts of Calotropis procera Linn
SY Mudi, A Bukar
Biokemistri , 2011,
Abstract: The leaves of Calotropis procera were air dried, grounded and soaked with ethanol. The extracts obtained (29.79g, CP1) was fractionated sequentially using aqueous methanol with petroleum ether, chloroform and ethyl acetate respectively. The residue of ethanol extract (marc) was extracted with 5M HCl, basified and extracted with chloroform. These were labeled as CP1-01 to CP1-05 for the plant. Each of these fractions was phytochemically screened to detect the class of secondary metabolite present. The fractions obtained from the plant were found to be selectively active against brine shrimp larvae. These fractions were also subjected to antimalaria parasites bioassay. Fractions CP1, CP1-04 and CP1-05 were found to be active against tested organisms, withCP1-04 being the most active. CP1-04 was further subjected to activity guided column chromatography that led to the isolation of two pure compounds CP1-04-1 and CP1-04-61. Compound CP1-04-61 was found to be active against the malaria parasite. This was further purified and subjected to qualitative and quantitative analysis.
Phytochemical Screening and Antimicrobial Activities of Terminalia catappa, Leaf Extracts
A Muhammad, Y Mudi
Biokemistri , 2011,
Abstract: The powdered leaf of Terminalia catappa was extracted using ethanol and partitioned into n-hexane, chloroform, ethyl acetate and aqueous methanol fractions. Test for the presence of secondary metabolites showed the presence of alkaloids, reducing sugars, saponins, tannins, resins and steroids in ethanol soluble fraction. The antimicrobial assay of n-hexane, chloroform and ethyl acetate fractions indicated a positive activity against the bacterial isolates tested. Chloroform fraction showed activity against Gram-negative Escherichia coli and Salmonella typhi at 500ìg/disc, while ethanol and aqueous methanol fractions were active only on Salmonella typhi at concentrations of 300 – 500ìg/disc. The present study revealed that the plant extracts contain phytochemicals responsible for the activity against Salmonella typhi.
Effect of the Berendsen thermostat on dynamical properties of water
Anirban Mudi,Charusita Chakravarty
Physics , 2004, DOI: 10.1080/00268970410001698937
Abstract: The effect of the Berendsen thermostat on the dynamical properties of bulk SPC/E water is tested by generating power spectra associated with fluctuations in various observables. The Berendsen thermostat is found to be very effective in preserving temporal correlations in fluctuations of tagged particle quantities over a very wide range of frequencies. Even correlations in fluctuations of global properties, such as the total potential energy, are well-preserved for time periods shorter than the thermostat time constant. Deviations in dynamical behaviour from the microcanonical limit do not, however, always decrease smoothly with increasing values of the thermostat time constant but may be somewhat larger for some intermediate values of $\tau_B$, specially in the supercooled regime, which are similar to time scales for slow relaxation processes in bulk water.
Advanced Deterioration Diagnosis Model for Building External Wall Tiles  [PDF]
Sy-Jye Guo
World Journal of Engineering and Technology (WJET) , 2018, DOI: 10.4236/wjet.2018.62B001
Abstract:
In 1981 Taiwan entered a period of intense construction, meaning that today many buildings are more than 30 years old. Lack of maintenance has led to frequent safety incidents involving external walls. This study focuses on a deterioration diagnostic model for external wall tiles of aged buildings, using both stage 1 and stage 2 diagnostic methods. The visual test results are categorized based on impact on public safety, and renovation strategies are proposed. Stage 1 diagnosis mainly adopted the DER visual inspection deterioration assessment method. For enhance the accuracy, this research adopted the Infrared Thermal Imaging detection method to double confirm the visual inspection results. After producing an external wall tile Condition Indicator (CI). For stage 1 diagnostic results that fall in a gray area, stage 2 diagnosis was carried out using a tap tone test, followed by fast Fourier transform and pattern recognition to analyze the tapping results. Finally, the study provides a deterioration evaluation criteria for external wall tiles replacement recommendations and a standard operating procedure for deterioration diagnosis. The study also recommends directions for future amendment of regulations, and provides a basis of reference for the government in determining urban renewal, renovation and maintenance strategies.
Modeling Off-Shore Wind Turbine Construction Project Subject to Impact of Wind Uncertainty  [PDF]
Sy-Jye Guo
World Journal of Engineering and Technology (WJET) , 2019, DOI: 10.4236/wjet.2019.72B005
Abstract:
Offshore wind farm is a key item in green energy and sustainable development. The Taiwan strait owns the world-class wind farm with average wind speed of 12 m/s and a potential for 3000 hours/year of power generation. Compared to wind turbines on land, the offshore wind turbine provide more stable power and less obstacles as well as less power loss. The potential and advantages of offshore wind farm development in the Taiwan strait has become the aims of the Taiwan government policy from now to 2025. This research will collect the historical climate data (wind and wave) of the Taiwan offshore wind farm in the Chan-hwa county. Combined the productivity loss respected to the installation of wind turbine due to different wind speed effect, as well as the productivity loss respected to the construction of pile foundation due to different wave height effect, this study will build up a total project duration forecast system based on the historical climate data of the offshore wind farm. Even the literature views from the experienced projects in North Europe including UK, Netherland and Spain, the climate uncertainty still plays a significant factor of the total construction duration for offshore wind farm. The results of this research can provide a more scientific and reliable duration forecast for future offshore wind farms construction in Taiwan.
Antimalaria activity of ethanolic extracts of leaves of Terminalia catappa. L. Combretaceae (indian almond)
S.Y Mudi, A Muhammad
Bayero Journal of Pure and Applied Sciences , 2009,
Abstract: The leaves of Terminalia catappa were air dried, grounded and soaked with ethanol. The extracts obtained (47.23g, TC1) was fractionated sequentially using aqueous methanol with petroleum ether, chloroform and ethyl acetate respectively. The residue of ethanol extract (marc) was extracted with 5M HCl, basified and extracted with chloroform. These were labeled as TC1-01–TC1-05 for the plant. Each of these fractions was phytochemically screened to detect the class of secondary metabolite present. The fractions obtained from the plant were found to be selectively active against brine shrimp larvae. These fractions were also subjected to antimalaria parasites bioassay. Fractions TC1, TC1-02 and TC1-05 were found to be active against tested organisms, with TC1-02 being the most active. TC1-02 was further subjected to activity guided column chromatography that led to the isolation of two pure compounds TC1-02-1 and TC1-02-64. Compound TC1-02-64 was found to be active against the malaria parasite. This was further purified and subjected to qualitative and quantitative analysis. Key Words: Fractionation, Antimalaria, Ethanol, Column Chromatography,Terminalia catappa.
Screening of barley cultivars against Helminthosporium sativum and the stability of disease reactions and yield
NITAI MUDI, SUNITA MAHAPATRA, SRIKANTA DAS*
Indian Phytopathology , 2011,
Abstract:
Spectral Signatures of the Diffusional Anomaly in Water
Anirban Mudi,Charusita Chakravarty,Ramakrishna Ramaswamy
Physics , 2004, DOI: 10.1063/1.1860555
Abstract: Analysis of power spectrum profiles for various tagged particle quantities in bulk SPC/E water is used to demonstrate that variations in mobility associated with the diffusional anomaly are mirrored in the exponent of the \onebyf\ region. Monitoring of \onebyf behaviour is shown to be a simple and direct method for linking phenomena on three distinctive length and time scales: the local molecular environment, hydrogen bond network reorganisations and the diffusivity. The results indicate that experimental studies of supercooled water to probe the density dependence of $1/f^\alpha$ spectral features, or equivalent stretched exponential behaviour in time-correlation functions, will be of interest.
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