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Search Results: 1 - 10 of 173 matches for " SONAWANE KD "
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QUANTUM CHEMICAL STUDY TO INVESTIGATE THE EFFECTS OF 5′-3′ DIPHOSPHATE BACKBONE ON THE CONFORMATION OF HYPERMODIFIED NUCLEOTIDE LYSIDINE (K2C) OCCUR AT WOBBLE (34TH) POSITION IN THE ANTICODON LOOP OF TRNAILE
SONAWANE KD,KUMBHAR BV,KUMBHAR NM,SAMBHARE SB
International Journal of Bioinformatics Research , 2011,
Abstract: Conformational preferences of hypermodified nucleotide ‘lysidine’ in the model diphosphate (Me-p-k2Cp-Me) segment of anticodon loop of tRNAIle have been studied by using quantum chemical perturbativeconfiguration interaction with localized orbitals (PCILO) method. The consequences of 5′-3′ diphosphate backboneon the conformation of zwitterionic, non-zwitterionic, neutral and tautomeric forms of lysidine have beeninvestigated and compared with diphosphate backbone of cytidine nucleotide. Automated geometry optimizationusing semi-empirical quantum chemical RM1, quantum mechanical Hartree-Fock (HF-SCF) and DensityFunctional Theory (B3LYP/6-31G**) calculations have also been made to compare the salient features. Theorientation of lysine moiety is found trans to the N(1) of cytidine in the predicted most stable conformations of allthe four forms of lysidine in the model 5′-3′ diphosphate anticodon loop segment. The lysine substituent folds backand form hydrogen bond with 2′-hydroxyl group of ribose sugar. Lysine substituent of various diphosphate lysidinenucleotides does not interact with 5′or 3′ diphosphate backbone. All forms of lysidine nucleotides retain anti (χ=3 )glycosyl (glycosidic) torsion angle. Diphosphate cytidine nucleotide prefers (χ=33 ), which could destabilize thec3′-endo sugar to the minor extent. The interaction between O(12b)----HO2′ of tautomer diphosphate nucleotidemay help in maintaining the c3′-endo sugar puckering at wobble (34th) position as compared to other lysidineforms and cytidine nucleotide. Hence, tautomeric form of lysidine along with suitable hydrogen bond donoracceptorgroups may also provide structural stability for the proper recognition of AUA codons instead of AUGcodons.
Enhancing Mobile Cloud Computing Security Using Steganography  [PDF]
Hassan Reza, Madhuri Sonawane
Journal of Information Security (JIS) , 2016, DOI: 10.4236/jis.2016.74020
Abstract: Cloud computing is an emerging and popular method of accessing shared and dynamically configurable resources via the computer network on demand. Cloud computing is excessively used by mobile applications to offload data over the network to the cloud. There are some security and privacy concerns using both mobile devices to offload data to the facilities provided by the cloud providers. One of the critical threats facing cloud users is the unauthorized access by the insiders (cloud administrators) or the justification of location where the cloud providers operating. Although, there exist variety of security mechanisms to prevent unauthorized access by unauthorized user by the cloud administration, but there is no security provision to prevent unauthorized access by the cloud administrators to the client data on the cloud computing. In this paper, we demonstrate how steganography, which is a secrecy method to hide information, can be used to enhance the security and privacy of data (images) maintained on the cloud by mobile applications. Our proposed model works with a key, which is embedded in the image along with the data, to provide an additional layer of security, namely, confidentiality of data. The practicality of the proposed method is represented via a simple case study.
Book Review: "Can NGOs make a difference? The challenge of development alternatives"
KD Helliker
African Sociological Review / Revue Africaine de Sociologie , 2008,
Abstract: Anthony J. Bebbington, Samuel Hickey and Diana C. Miltin, eds.,"Can NGOs Make a Difference? The Challenge of Development Alternatives". London, Zed Books, 2008. Reviewed by Kirk D. Helliker Department of Sociology Rhodes University Grahamstown South Africa
Analysis of Default Risk of Agricultural Loan by Some Selected Commercial Banks in Osogbo, Osun State, Nigeria
KD Adedapo
International Journal of Applied Agriculture and Apiculture Research , 2007,
Abstract: This study examines the default risk involved in agricultural loan and determines the effect it has on the level of loan given to farmers in Osogbo agricultural zone of Osun State. Relevant data were collected from selected commercial banks in the study area through the use of questionnaire. The data collected were analyzed using descriptive statistics, multiple regression as well as risk analytical techniques (default risk and default rate). It was discovered that both the default rate and default risk were high with an average of more than 50% and 1.3 respectively. This has led to the unwillingness of the banks to grant loan for agricultural purposes. It was therefore recommended that banks should give revolving loan to farmers cooperative societies to reduce default rate and loan diversions since members can serve as watch dog to each other. Banks should also prevent unnecessary delay in loan disbursement to allow for timely use of the loan. Banks should also explore the Agricultural credit guarantee scheme (ACGS) to offset part of the risk in case of default.
The in vitro antimicrobial activity of fruit and leaf crude extracts of Momordica charantia: A Tanzania medicinal plant
KD Mwambete
African Health Sciences , 2009,
Abstract: Objective: To evaluate the antimicrobial activity of Momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens. Method: Petroleum ether and methanolic crude extracts of fruits and leaves of the plant were evaluated for antimicrobial activity using the disk diffusion method on four reference microorganisms (Pseudomonas aeruginosa, Escherichia coli, Candida albicans and Staphylococcus aureus; and four clinical strains of Klebsiella pneumoniae, Proteus vulgaris, Salmonella typhi and Cryptococcus neoformans. Result: Antimicrobial activity was observed against all the tested microorganisms with exception to P. mirabilis and C. neoformans. Methanolic crude extracts exhibited relatively broader antimicrobial spectrum of activity than petroleum ether extracts with the as lower concentration as 0.075mg/μl. Methanolic fruit crude extract displayed the broadest antimicrobial spectrum by inhibiting majority (75%) of the tested microorganisms. Neither was there synergistic nor addition effect upon mixing leaf and fruit extracts of equal concentrations derived from the same solvent. Conclusion: Extracts of M.charantia demonstrated antimicrobial activity on tested microorganisms except on Proteus mirabilis and Cryptococcus neoformans. Fruit extracts showed higher antimicrobial activity than leaf extract. Further studies are recommended that will involve various parts of the plant, select different fractions of extracts and purify the active antimicrobial components
Traditional leadership factor in modern local government system in Ghana: policy Implementation, role conflict and marginalization
KD Kessey
Journal of Science and Technology (Ghana) , 2006,
Abstract: The search for appropriate institutional framework for local governance and development has been a difficult task in Africa. Although Traditional Authorities are authentic and time-tested institutions of governance, their role has been politically, administratively, and financially marginalized since the introduction of modern local government system. The focus of this paper is the discussion on the various local government structures, policies and their marginalization strategies. The discussions include indirect rule, establishment of town councils, introduction of public treasuries, the first and second republican local government models and the decentralized system of government with creation of District Assemblies. Some of the strengths and weaknesses of the systems were discussed. The issue of local taxation and the bias of the revenue distribution formula against Traditional Councils are also discussed. The Stool Land Revenue (SLR) shared among Traditional Authorities (TAs) is only 7 per cent of the District Assemblies Common Fund (Grants). The District Assemblies receive 55 per cent of the SLR plus DACF. The political structures, taxation authority, distribution of SLR, and Grants are used as tools to marginalize the traditional authorities. While the performance of some modern local government institutions, as agents of local development, is poor the development efforts of some Traditional Authorities at promoting education, health and environmental management, are highly commendable in Ghana. This indicates that Traditional Councils have potentials that are not fully harnessed due to marginalization. Modern local government stands to gain if Traditional Authorities become active partners and their potentials harnessed for development.
Maternal death review: A path to achieve the Millennium Development Goal of improving maternal health
KD Kassaye
Ethiopian Journal of Health Development , 2006,
Abstract:
The Design and Construction of a Portable Kerosene Pressure-Cooker
KD Moh
African Research Review , 2010,
Abstract: This paper dealt with the design and construction of a portable kerosene pressure-cooker. The existing cookers and the problems associated with them were analyzed. The need and importance of this work were also high highlighted. The design consists of three parts: the cylinder, the piping, and the frame. The R-12 refrigerant cylinder was redesigned to suit the kerosene cylinder, since it has the desirable features for that purpose. Using the principles of fluid dynamics, this work was able to establish that the power of the cooker is 179.922KW, and that under a constant pressure of IMPa the cooker will discharge and burn 1 litre of kerosene in 3.5 minutes giving out an enormous heat energy of 38.2MJ Key Words: Volumetric flow rate, mass flow rate, power, energy, pressure.
Politics and Constitutional Adjudication: A response to Prof F Venter
KD Chetty
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad , 2003,
Abstract: Colloquium presentation - no abstract available
DECISION SUPPORT SYSTEM FOR HEART DISEASE BASED ON SEQUENTIAL MINIMAL OPTIMIZATION IN SUPPORT VECTOR MACHINE
Deepti Vadicherla,Sheetal Sonawane
International Journal of Engineering Sciences and Emerging Technologies , 2013,
Abstract: Computer based medical decision support system (MDSS) can be useful for the physicians with its fast and accurate decision making process. Predicting the existence of heart disease accurately, results in saving life of patients followed by proper treatment. The main objective of our paper is to present a MDSS for heart disease classification based on sequential minimal optimization (SMO) technique in support vector machine (SVM). In this we illustrated the UCI machine learning repository data of Cleveland heart disease database; we trained SVM by using SMO technique. Training a SVM requires the solution of a very large QP optimization problem..SMO algorithm breaks this large optimization problem into small sub-problems. Both the training and testing phases give the accuracy on each record. The results proved that the MDSS is able to carry out heart disease diagnosis accurately in fast way and on a large dataset it shown good ability of prediction.
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