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Search Results: 1 - 10 of 50638 matches for " SILVA "
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Antitumor Activity of Disintegrin-Like Components from the Venom of Montivipera raddei  [PDF]
Silva Amiryan
Journal of Cancer Therapy (JCT) , 2011, DOI: 10.4236/jct.2011.25101
Abstract: Our findings represent the first report of the antitumor activity of the disintegrin-like components from the venom of Armenian viper (M. raddei). The venom of M. raddei was separated by reverse phase high-performance liquid chroma-tography (RP HPLC), and individual fractions were analyzed for disintegrin activity. Disintegrin-like components from the venom of M. raddei, by blocking integrins on breast cancer cells (MDA-MB-435), not only interferes with adhesion of breast cancer cells to the extracellular matrix, but also inhibits cellular mobility which is essential for cancer invasion. These effects seriously curtail the metastatic capability of the MDA-MB-435 cells.
Nutritional Quality and Health Benefits of Vegetables: A Review  [PDF]
Jo?o Silva Dias
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.310179
Abstract: Vegetables are considered essential for well-balanced diets since they supply vitamins, minerals, dietary fiber, and phytochemicals. Each vegetable group contains an unique combination and amount of these phytonutriceuticals, which distinguishes them from other groups and vegetables whithin their own group. In the daily diet vegetables have been strongly associated with improvement of gastrointestinal health, good vision, and reduced risk of heart disease, stroke, chronic diseases such as diabetes, and some forms of cancer. Some phytochemicals of vegetables are strong antioxidants and are thought to reduce the risk of chronic disease by protecting against free radical damage, by modifying metabolic activation and detoxification of carcinogens, or even by influencing processes that alter the course of tumor cells. All the vegetables may offer protection to humans against chronic diseases. Nutrition is both a quantity and a quality issue, and vegetables in all their many forms ensure an adequate intake of most vitamins and nutrients, dietary fibers, and phytochemicals which can bring a much-needed measure of balance back to diets contributing to solve many of these nutrition problems. The promotion of healthy vegetable products has coincided with a surging consumer interested in the healthy functionality of food. Because each vegetable contains a unique combination of phytonutriceuticals, a great diversity of vegetables should be eaten to ensure that individual’s diet includes a combination of phytonutriceuticals and to get all the health benefits. This article make a review and discusses the nutritional quality and health benefits of the major groups of vegetables. More interdisciplinary work is required that involves nutritional and food scientists as well as others from biomedical fields to ascertain the thrue function of specific phytonutriceuticals.
Anaphylatoxins: From Supposed Toxin Anaphylactics to Effective Mediators of the Early Events of Inflammation  [PDF]
Wilmar Dias da Silva
Open Journal of Veterinary Medicine (OJVM) , 2012, DOI: 10.4236/ojvm.2012.24043
Abstract: This review updates original data describing the experiments showing the complement origin of anaphylatoxins unexplainable submerged under the surface of the articles related to the subject. Next, recalls subsequent data describing the anaphylatoxins peptide nature and sequences, the cell receptors with which they interact and activate and the outcome of the cell responses. The review continues by highlighting the anaphylatoxin biological properties focusing on the unequivocal participation of these mediators in inflammation. The review concludes bringing data reinforcing the promising use of these peptides as molecular primers to create specific and efficient pharmacological antagonists.
Application of Laplace Transform for a Gas-Liquid-Solid Trickle Bed Reactor by Using the Tracer Technique  [PDF]
Jornandes Dias Silva
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.41A027

Experimental evaluation and dynamic modelling were presented for a liquid flow (H2O + NaOH tracer) on solid particles in a trickle bed reactor. One-dimensional dynamic mathematical model has been described to study the gas-liquid-solid process in which the liquid phase with the NaOH tracer is treated as a continuum. The physical model has been analyzed, including the formulation of initial and boundary conditions and the description of the solution methodology. An experimental setup to measure the concentrations of the NaOH tracer has been performed. The concentration measurements of this NaOH tracer have been performed in a fixed be reactor on trickling flow of the liquid phase for a range of operating conditions. The axial dispersion (Dax) of the liquid phase, liquid-solid mass transfer (kLS) coefficient and partial wetting efficiency (fe) were chosen as the hydrodynamic parameters of the proposed mathematical model. Such parameters have been optimized with experimental measurents of the NaOH tracer at the exit of the trickle-bed reactor. The optimized parameters (Dax, kLS, and fe) were calculated simultaneously by using the theoretical model with minimization of the objective function. Results of the proposed mathematical model have been presented and compared as of the two experimental cases. These hydrodynamic parameters were fitted by means of the empirical correlations.

Chiral Dirac Equation Derived From Quaternionic Maxwell’s Systems  [PDF]
Hector Torres-Silva
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2013, DOI: 10.4236/jemaa.2013.53017

In the present article we propose a simple equality involving the Dirac operator and the Maxwell operators under chiral approach. This equality establishes a direct connection between solutions of the two systems and moreover, we show that it is valid when the natural relation between the frequency of the electromagnetic wave and the energy of the Dirac particle is fulfilled if the electric field E is parallel to the magnetic field H. Our analysis is based on the quaternionic form of the Dirac equation and on the quaternionic form of the Maxwell equations. In both cases these reformulations are completely equivalent to the traditional form of the Dirac and Maxwell systems. This theory is a new quantum mechanics (QM) interpretation. The below research proves that the QM represents the electrodynamics of the curvilinear closed chiral waves. It is entirely according to the modern interpretation and explains the particularities and the results of the quantum field theory. Also this work may help to clarify the controversial relation between Maxwell and Dirac equations while presenting an original way to derive the Dirac equation from the chiral electrodynamics, leading, perhaps, to novel conception in interactions between matter and electromagnetic fields. This approach may give a reinterpretation of Majorana equation, neutrino mass, violation of Heinsenberg’s measurement-disturbation relationship and mass generation in systems like graphene devices.

Globalization, Cultural Change and Religion: The Case of Pentecostalism  [PDF]
Alberto da Silva Moreira
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.24043
Abstract: The challenges faced by this paper are two folds: to understanding how cultural changes brought about by globalization can influence religions and, conversely, how religions can influence broader cultural change. Globalization has spread powerful cultural forms, such as international popular consumer culture, media culture and the culture of the individual. These cultural forms or horizons interact with and transform local cultures which are often intertwined with traditional religions. Throughout this process, traditional religion can weaken its potential to express local cultures, but can also become a vehicle used to express strategies of identity affirmation. Many modalities of globalization-compatible religion, like Pentecostalism, are also consistently penetrated by consumer culture, media culture and individualism. When they interact with traditional religion, they often function as a critical dissolving factor. Therefore, Pentecostalism and similar religions have themselves become active factors in (global) cultural change processes.
Optimal Aggregate Production Plans via a Constrained LQG Model  [PDF]
Oscar S. Silva Filho
Engineering (ENG) , 2014, DOI: 10.4236/eng.2014.612075
Abstract: In this paper, a single product, multi-period, aggregate production planning problem is formulated as a linear-quadratic Gaussian (LQG) optimal control model with chance constraints on state and control variables. Such formulation is based on a classical production planning model developed in 1960 by Holt, Modigliani, Muth and Simon, and known, since then, as the HMMS model [1]. The proposed LQG model extends the HMMS model, taking into account both chance-constraints on the decision variables and data generating process, based on ARMA model, to represent the fluctuation of demand. Using the certainty-equivalence principle, the constrained LQG model can be transformed into an equivalent, but deterministic model, which is called here as Mean Value Problem (MVP). This problem preserves the main properties of the original model such as convexity and some statistical moments. Besides, it is easier to be implemented and solved numerically than its stochastic version. In addition, two very simple suboptimal procedures from stochastic control theory are briefly discussed. Finally, an illustrative example is introduced to show how the extended HMMS model can be used to develop plans and to generate production scenarios.
The Crisis of Religious Identity and Religious Landscape in Contemporary Brazil  [PDF]
Alberto da Silva Moreira
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.210003
Abstract: Inserted in the processes of economic, political and cultural globalization, there is a crisis within traditional meaning-producing and identity-creating institutions, such as the state, family, school and traditional religions, going on in Brazil and in other Latin American countries. If in the 1930s being Brazilian and Catholic were considered two sides of the same national religious identity coin, which could be applied, mutatis mutandis, to other countries in the region, today Brazil is rapidly becoming a multi-cultural and multi-religious country. It remains the largest Catholic country, but is also already the largest Pentecostal and the largest Spiritualist country in the world. In addition, other religious minorities, such as African-Brazilian religions, Buddhists, Muslims and Jews increasingly occupy the public sphere. Parallel to this shift, there is a significant effort being put forth by many Brazilian and South American religious communities to expand on a global level, such as the Pentecostals, charismatic Catholics, Spiritualists and Afro-Brazilian communities. This presentation analyzes the causes and the data related to this religious and identity change and highlights some trends for the future.
Interactive Digital Games for Geography Teaching and Understanding Geographical Space  [PDF]
Christian Nunes da Silva
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.67070
Abstract: This article aims to analyze and discuss the use of digital interactive games, such as learning tools to be used by educators in the classroom, as a resource for geography teaching-learning process in the early grades. This discussion arose from the analysis by geography course graduation students of the Federal University of Pará (UFPA), in the years 2013 and 2014, at which this tool has gained recognition of its potential by students. In this sense, the objective is a brief discussion, based on the analysis of some selected examples on how these digital games can become fundamental importance of resources for teaching Geography and how these should be used and applied in the classroom by educators in a critical way, which will allow students to have adequate learning about the geographic space.
Nutritional Quality and Effect on Disease Prevention of Vegetables  [PDF]
Jo?o Silva Dias
Food and Nutrition Sciences (FNS) , 2019, DOI: 10.4236/fns.2019.104029
Abstract: Vegetables have remarkable nutritional and health benefits. There are good reasons to include vegetables in human diet since they are enriched in bioactive compounds and by this reason they may help reduce the risk of some diseases. In this paper it was analyzed the nutrition quality and effect on disease prevention of vegetables. Each vegetable family and each vegetable contain a unique combination of bioactive compounds. The health benefit of vegetables should not be linked to one type of vegetable. It is presented some experimental research evidences that vegetables exert anti-oxidative, anti-carcinogenic, anti-diabetic and cardiovascular disease lowering effects. The mechanism by which vegetable bioactive compounds decrease the risk of some of these diseases is complex and sometimes unknown.
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