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Search Results: 1 - 10 of 23382 matches for " SHI Gaojun "
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E-Selectin Gene Polymorphisms and Essential Hypertension in Asian Population: An Updated Meta-Analysis
Gaojun Cai, Bifeng Zhang, Weijin Weng, Ganwei Shi, Sheliang Xue, Yanbin Song, Chunyan Ma
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0102058
Abstract: Objective Epidemiological studies have shown that E-selectin gene polymorphisms (A561C and C1839T) may be associated with essential hypertension (EH), but the results are conflicting in different ethnic populations. Thus, we performed this meta-analysis to investigate a more authentic association between E-selectin gene polymorphisms and the risk of EH. Methods We searched the relevant studies for the present meta-analysis from the following electronic databases: PubMed, Embase, Cochrane Library, Google Scholar, Web of Science, Wanfang Data, and China National Knowledge Infrastructure (CNKI). Odds ratios (OR) with 95% confidence interval (CI) were used to evaluate the strength of the association between E-selectin gene polymorphisms and EH susceptibility. The pooled ORs were performed for dominant model, allelic model and recessive model. The publication bias was examined by Begg’s funnel plots and Egger’s test. Results A total of eleven studies met the inclusion criteria. All studies came from Asians. Ten studies (12 cohorts) evaluated the A561C polymorphism and EH risk, including 2,813 cases and 2,817 controls. The pooled OR was 2.280 (95%CI: 1.893–2.748, P<0.001) in dominant model, 5.284 (95%CI: 2.679–10.420, P<0.001) in recessive model and 2.359 (95%CI: 1.981–2.808, P = 0.001) in allelic model. Four studies (six cohorts) evaluated C1839T polymorphism and EH risk, including 1,700 cases and 1,681 controls. The pooled OR was 0.785 (95%CI: 0.627–0.983, P = 0.035) in dominant model, 1.250 (95%CI: 0.336–4.652, P = 0.739) in recessive model and 0.805 (95%CI: 0.649–0.999, P = 0.049) in allelic model. Conclusion The current meta-analysis concludes that the C allele of E-selectin A561C gene polymorphism might increase the EH risk in Asian population, whereas the T allele of E-selectin C1839T gene polymorphism might decrease the EH risk.
Analysis of major components in water based stamp pad inks and their imprints by ultra high performance liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry
超高效液相色谱-质谱联用法与气相色谱-质谱联用法分析水性印油印记的主要成分

ZHANG Qing,ZOU Jixin,SHI Gaojun,ZHANG Lijuan,
章晴
,邹积鑫,石高军,张丽娟

色谱 , 2010,
Abstract: Ultra high performance liquid chromatography-mass spectrometry (UHPLC-MS) technology and gas chromatography-mass spectrometry (GC-MS) technology were used to qualitatively analyze the major components in water based stamp pad inks including major colorants and volatile components. After the samples were supersonically extracted and then centrifuged, UHPLC-MS was used to separate and identify the major colorants. A ZORBAX Eclipse Plus Phenyl-Hexyl (50 mm×4.6 mm, 1.8 μm) column and 15 mmol/L ammonium acetate-acetonitrile were utilized for the separation and negative selected ion monitoring mode (SIM) was set for the MS analysis. An HP-INNOWAX (30 m×0.25 mm, 0.25 μm) column was employed in the GC-MS analysis with the full-scan mode to determine the volatiles. This study demonstrated that the major colorants in the inks and their imprints were Acid Red R, Eosin Y and Pigment Red 112| and the major volatiles were glycerol, 1,2-propanediol, etc. The method is rapid and accurate. It also demonstrates that the method can meet the requirements for imprint determination in material evidence identification. The work provides a reliable tool for the categorization research in the forensic sciences.
Coverage Problem in Wireless Sensor Network: A Survey
Gaojun Fan,Shiyao Jin
Journal of Networks , 2010, DOI: 10.4304/jnw.5.9.1033-1040
Abstract: Wireless sensor networks constitute the platform of a broad range of applications related to national security, surveillance, military, health care, and environmental monitoring. The coverage of WSN has answered the questions about quality of service (surveillance) which can be provided by WSN. Therefore, maximizing coverage using the resource constrained nodes is a non-trivial problem. The coverage problem for wireless sensor network (WSN) has been studied extensively in recent years, especially when combined with connectivity and energy efficiency. In this paper we present a survey of coverage problem. And besides some basic design considerations in coverage of WSN we describe two challenges, namely, maximizing network lifetime and network connectivity. We also provide a brief summary and comparison of existing coverage schemes.
Atypical CT and MRI Features of Focal Nodular Hyperplasia of Liver: A Study with Radiologic-Pathologic Correlation  [PDF]
Narendra Darai, Rongbao Shu, Rajkumar Gurung, Xiaojuan Zhang, Gaojun Teng
Open Journal of Radiology (OJRad) , 2015, DOI: 10.4236/ojrad.2015.53020
Abstract: Focal Nodular Hyperplasia (FNH) is the second most hepatic tumor next to hemangioma predominantly affecting women. It is a benign regenerative nodule having an unencapsulated well-defined mass with fibrovascular septae and proliferating bile ductules. Gadoxetic acid is a hepatocyte specific MR contrast agent which is known to be specific for the identifying FNH. Congenital vascular malformation and enlargement due to hormone stimulation is being considered as the main cause of FNH. The central stellate fibrovascular scar is a typical diagnostic imaging feature of FNH and the atypical pathological findings of FNH include large lesions multiple in number, internal necrosis, haemorrhagic foci and fatty infiltration. The atypical imaging features include non-enhancement of the central scar, calcification of the lesion, nonvisualized central scar and pseudocapsular enhancement on delayed imaging. For the accurate diagnosis of FNH, study of atypical radiologic features of FNH in correlation with pathological findings is the most essential. The macroscopic and the microscopic pathognomic changes should be taken as helpful points in the diagnosis of FNH. The main objective of this study is to recognize and understand the typical and atypical imaging patterns observed in CT and MR imaging of FNH with pathological correlation which avoids the necessity of biopsy and further investigations.
Comparison with Surgical Findings for the Accuracy of Routine MRI in Rotator Cuff Tears  [PDF]
Narendra Darai, Suvash Pokhrel, Rongbao Shu, Xiaojuan Zhang, Jiacheng Liu, Gaojun Teng
Open Journal of Radiology (OJRad) , 2016, DOI: 10.4236/ojrad.2016.62011
Abstract: Objective: To evaluate the diagnostic efficacy of magnetic resonance imaging (MRI) for the detection of partial-thickness rotator cuff tears (PTT) and full-thickness rotator cuff tears(FTT) by comparing its findings with surgical findings as the gold standard and to improve the previous MRI accuracy in diagnosing rotator cuff tears (RCT) considering more variables. Methods: In 45 months, 804 patients underwent MRI shoulder joint. Among them, only 95 cases had undergone both MRI imaging and surgery accordingly. The patient records were evaluated retrospectively if MRI and surgery were performed within 40 days of MRI. MRI findings were categorized into PTT, FTT and no tears which were further divided into different types according to four main nominal data as variables viz. site, size, shape and muscle involvement in RCT and were correlated with surgical findings for statistical calculation by using Kappa coefficient and McNemar Bowker test. Results: 81 patients (86 RCTs) underwent surgery within 40 days. On the basis of site as variable, MRI correctly depicted 100% of full thickness tears(FTT), 85% of bursal partial thickness tears(PTT), 80.4% of articular partial thickness tears(PTT). The consistency in diagnosis of RCT between MRI and surgery was moderate (Kappa coefficient 0.645). Overall sensitivity, specificity and accuracy of MRI for diagnosing PTT was 87.3%, 53.3% and 81.3%; and that for FTT was 100%, 98.7% and 98.8% respectively. Likewise on the basis of size, shape and muscles involved, the consistency between MRI and surgery was poor for size and shape and moderate for muscles involved; and the difference in diagnosing RCT by MRI and surgery was significant for shape (P = 0.002) only, but not significant for size (P = 0.16) and for muscles involved (P = 0.206) respectively. The agreement between MRI and surgery in diagnosing calcific tendinitis and shoulder joint hematoma with Kappa coefficient is (0.577) and (0.556) respectively. Conclusion: MRI has better accuracy for detecting FTT and has high sensitivity and positive predictive value in diagnosing both PTT and FTT. Combining more others variables in addition to RCT, MRI offers a great value in diagnosing RCT.
Sr-Nd isotope geochemistry of eolian dust of the arid-semiarid areas in China: Implications for loess provenance and monsoon evolution
Wenbo Rao,Jiedong Yang,Jun Chen,Gaojun Li
Chinese Science Bulletin , 2006, DOI: 10.1007/s11434-006-2008-1
Abstract: Minerals and rocks have distinct 87Sr/86Sr and 143Nd/144Nd ratios, depending on their geological origin and ages, and these isotope ratios are less altered than elemental composition during transport in the atmosphere or after deposition as sediments, thus stable isotopes of Sr and Nd have great potential as tracers for provenance and transport of materials. During the hypergene process, Sr isotope ratios of sediments are controlled by their parent rocks, particle sizes and chemical weathering. In general, the higher the Sr isotope ratios of parent rocks, and/or the more the fine-grained fractions, and/or the stronger the chemical weathering, thus the higher the Sr isotope ratios of sediments. On the contrary, there are lower Sr isotope ratios of sediments. Nd isotope ratios of sediments, independent of their particle sizes and chemical weathering, are only associated with parent rocks. For the provenance of the Chinese Loess Plateau, different reseachers drew discordant and even contradictory conclusions by using the method of Sr-Nd isotopic tracing. From the previous Nd isotope data, it is considered that the Tarim Basin, deserts in the central and west parts of Inner Mongolia and the Tibetan Plateau are the main sources of the Chinese Loess Plateau, and are also manufacturers for eolian dust of the Far East regions, together with the Chinese Loess Plateau. Sr isotope ratios of eolian dust are solely affected by wind sorting and weathering-pedogenesis due to its homogeneous composition in the Chinese Loess Plateau. Wind sorting is related to the East Asian winter monsoon but weathering-pedogenesis is mainly associated with the East Asian summer monsoon. Studies on Sr isotopic compositions of the loess-paleosol sequence suggest that 87Sr/86Sr ratios in acid-soluble materials are an index for chemical weathering intensity of the Chinese Loess Plateau, indicating the East Asian summer monsoon variations, whereas 87Sr/86Sr ratios in acid-insoluble materials are significantly controlled by particle sizes, and can be used as a proxy indicator reflecting the East Asian winter monsoon variations. Variations of 87Sr/86Sr ratios in acid-insoluble materials in the past 2.6Ma further demonstrate that the East Asian winter monsoon gradually strengthened since the beginning of the Quaternary period. This result agrees with the prior conclusion that climate gradually cooled since the onset of the Quaternary Ice Age.
An improved hierarchical generic object recognition algorithm based on neural sparse coding
一种融合神经稀疏编码机制的层次目标识别算法

qianlele,gaojun,xiezhao,
钱乐乐
,高隽,谢昭

中国图象图形学报 , 2010,
Abstract: 针对基本层次化目标识别计算模型缺乏明确学习概念和有效学习方法的问题,利用神经稀疏编码的学习规则,生成原型向量集合。通过模拟复杂细胞的感受野特性,实现层次化的稀疏编码过程,提出基于神经稀疏编码的层次目标特征提取算法。并利用简化的分类器设计,完成复杂场景下的广义目标识别问题。在Caltech101数据库上进行实验对比,结果表明本文算法相对Serre计算模型在识别正确率上有较大提高,时间复杂度增加并不明显,且更加符合生物视觉机理。
Effect of low-intensity pulsed ultrasound on biocompatibility and cellular uptake of chitosan-TPP nanoparticles
Junyi Wu,Gaojun Liu,Yi-Xian Qin,Yizhi Meng
Quantitative Biology , 2014,
Abstract: Using low molecular weight chitosan nanoparticles (CNPs) prepared by an ionic gelation method, we report the effect of low-intensity pulsed ultrasound (US) on cell viability and nanoparticle uptake in cultured murine pre-osteoblasts. Particle size and zeta potential are measured using Dynamic Light Scattering (DLS), and cell viability is evaluated using the MTS assay. Results show that 30 min delivery of CNPs at 0.5 mg/mL is able to prevent loss of cell viability due to either serum starvation or subsequent exposure to US (1 W/cm2 or 2 W/cm2, up to 1 min). Additionally, flow cytometry data suggest that there is a close association between cellular membrane integrity and the presence of CNPs when US at 2 W/cm2 is administered.
Discrimination for minimal hepatic encephalopathybased on Bayesian modeling of default mode network
Jiao Yun, Wang Xunheng, Tang Tianyu, Zhu Xiqi, Teng Gaojun
- , 2015, DOI: 10.3969/j.issn.1003-7985.2015.04.026
Abstract: In order to classify the minimal hepatic encephalopathy(MHE)patients from healthy controls, the independent component analysis(ICA)is used to generate the default mode network(DMN)from resting-state functional magnetic resonance imaging(fMRI). Then a Bayesian voxel-wised method, graphical-model-based multivariate analysis(GAMMA), is used to explore the associations between abnormal functional integration within DMN and clinical variable. Without any prior knowledge, five machine learning methods, namely, support vector machines(SVMs), classification and regression trees(CART), logistic regression, the Bayesian network, and C4.5, are applied to the classification. The functional integration patterns were alternative within DMN, which have the power to predict MHE with an accuracy of 98%. The GAMMA method generating functional integration patterns within DMN can become a simple, objective, and common imaging biomarker for detecting MHE and can serve as a supplement to the existing diagnostic methods.
Novel On-Line North-Seeking Method Based on a Three-Axis MEMS Gyroscope
Novel On-Line North-Seeking Method Based on a Three-Axis MEMS Gyroscope

Yu Liu,Gaojun Xiang,Junqi Guo,Min Zhou,Hongzhi Liu
- , 2018, DOI: 10.15918/j.jbit1004-0579.17128
Abstract: A novel on-line north-seeking method based on a three-axis micro-electro-mechanical system (MEMS) gyroscope is designed. This system processes data by using a Kalman filter to calibrate the installation error of the three-axis MEMS gyroscope in complex environment. The attitude angle updating for quaternion, based on which the attitude instrument will be rotated in real-time and the true north will be found. Our experimental platform constitutes the dual-axis electric rotary table and the attitude instrument, which is developed independently by our scientific research team. The experimental results show that the accuracy of north-seeking is higher than 1°, while the maximum root mean square error and the maximum mean absolute error are 0.906 7 and 0.910 0, respectively. The accuracy of north-seeking is much higher than the traditional method.
A novel on-line north-seeking method based on a three-axis micro-electro-mechanical system (MEMS) gyroscope is designed. This system processes data by using a Kalman filter to calibrate the installation error of the three-axis MEMS gyroscope in complex environment. The attitude angle updating for quaternion, based on which the attitude instrument will be rotated in real-time and the true north will be found. Our experimental platform constitutes the dual-axis electric rotary table and the attitude instrument, which is developed independently by our scientific research team. The experimental results show that the accuracy of north-seeking is higher than 1°, while the maximum root mean square error and the maximum mean absolute error are 0.906 7 and 0.910 0, respectively. The accuracy of north-seeking is much higher than the traditional method.
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